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Masato Okamoto
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Journal Articles

Abstract LB-219: Interleukin-8 promotes generation of M2 macrophages and arginase-producing granulocytes: Prognostic significance of interleukin-8 and infiltration of immune cells positive for CD163 and CD66b in tumor tissues in patients with oral squamous cell carcinoma

Masato Okamoto, Yohei Fujita, Hiroyuki Goda, Koh-ichi Nakashiro, Hiroyuki Hamakawa
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): LB-219.
https://doi.org/10.1158/1538-7445.AM2015-LB-219
Published: 01 August 2015
View articletitled, Abstract LB-219: Interleukin-8 promotes generation of M2 macrophages and arginase-producing granulocytes: Prognostic significance of interleukin-8 and infiltration of immune cells positive for CD163 and CD66b in tumor tissues in patients with oral squamous cell carcinoma
Journal Articles

Abstract 1685: HER2 upregulation induced by gemcitabine treatment augments antitumor effect of trastuzumab emtansine against pancreatic cancer

Shin Kan, Shigeo Koido, Masato Okamoto, Kazumi Hayashi, Masaki Ito, Yuko Kamata, Hideo Komita, Eijiro Nagasaki, Sadamu Homma
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 1685.
https://doi.org/10.1158/1538-7445.AM2014-1685
Published: 01 October 2014
View articletitled, Abstract 1685: HER2 upregulation induced by gemcitabine treatment augments antitumor effect of trastuzumab emtansine against pancreatic cancer
Journal Articles

Abstract 2813: Survival benefit of an add-on dendritic cell vaccine for patients with inoperable pancreatic cancer receiving chemotherapy: a multicenter study

Masanori Kobayashi, Shimodaira Shigetaka, Kazuhiro Nagai, Masahiro Ogasawara, Hidenori Takahashi, Hirofumi Abe, Mitsugu Tanii, Masato Okamoto, Shun-ichi Tsujitani, Masaki Nagaya, Yoshikazu Yonemitsu, The DC vaccine study group of Japan Society of Innovative Cell Therapy (J-SICT)
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 2813.
https://doi.org/10.1158/1538-7445.AM2014-2813
Published: 01 October 2014
View articletitled, Abstract 2813: Survival benefit of an add-on dendritic cell vaccine for patients with inoperable pancreatic cancer receiving chemotherapy: a multicenter study
Journal Articles

Abstract 5033: Down-regulation of PD-1 ligands by chemotherapeutic agents via inhibition of STAT3 activity enhances T cell-stimulating ability of dendritic cell

Masato Okamoto, Tomoyuki Tano, Hiroyuki Goda, Yohei Fujita, Koh-ichi Nakashiro, Hiroyuki Hamakawa
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 5033.
https://doi.org/10.1158/1538-7445.AM2014-5033
Published: 01 October 2014
View articletitled, Abstract 5033: Down-regulation of PD-1 ligands by chemotherapeutic agents via inhibition of STAT3 activity enhances T cell-stimulating ability of dendritic cell
Journal Articles

Abstract CT223: Dendritic cells pulsed with Wilms′ tumor gene 1 (WT1)-specific and MHC class I and II-restricted epitopes with gemcitabine induce antitumor immune responses in patients with advanced pancreatic cancer

Shigeo Koido, Sadamu Homma, Masato Okamoto, Masako Mori, Shinji Yoshizaki, Kazuki Takakura, Kazumi Hayashi, Shin Kan, Takafumi Ishidao, Sei-ichi Yusa, Shigetaka Shimodaira, Kan Uchiyama, Mikio Kajihara, Hiroo Imazu, Hiroshi Arakawa, Toshifumi Ohkusa, Hisao Tajiri
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): CT223.
https://doi.org/10.1158/1538-7445.AM2014-CT223
Published: 01 October 2014
View articletitled, Abstract CT223: Dendritic cells pulsed with Wilms′ tumor gene 1 (WT1)-specific and MHC class I and II-restricted epitopes with gemcitabine induce antitumor immune responses in patients with advanced pancreatic cancer
Journal Articles

Abstract 4722: Enhancement of the T cell-stimulating ability of dendritic cells by 5-FU via regulation of the expression of ligands for programed cell death 1.

Tomoyuki Tano, Masato Okamoto, Hiroyuki Goda, Yohei Fujita, Koh-ichi Nakashiro, Hiroyuki Hamakawa
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 4722.
https://doi.org/10.1158/1538-7445.AM2013-4722
Published: 15 April 2013
View articletitled, Abstract 4722: Enhancement of the T cell-stimulating ability of dendritic cells by 5-FU via regulation of the expression of ligands for programed cell death 1.
Journal Articles

Abstract 2840: Dendritic cell-based immunotherapy targeting WT1 and MUC1 for advanced biliary tract cancer.

Masanori Kobayashi, Tomoyo Sakabe, Mitsugu Tanii, Hirofumi Abe, Hedenori Takahashi, Shun-ichi Tsujitani, Shigetaka Shimodaira, Yoshikazu Yonemitsu, Masato Okamoto, Masaki Nagaya
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 2840.
https://doi.org/10.1158/1538-7445.AM2013-2840
Published: 15 April 2013
View articletitled, Abstract 2840: Dendritic cell-based immunotherapy targeting WT1 and MUC1 for advanced biliary tract cancer.
Journal Articles

Abstract 5372: Dendritic-cell based vaccine for advanced pancreatic cancer: A report of 39 cases treated in Seren Clinic Nagoya

Masanori Kobayashi, Tomoyo Sakabe, Shigehiro Kure, Masato Okamoto, Kiyoshi Yokokawa
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 5372.
https://doi.org/10.1158/1538-7445.AM2012-5372
Published: 15 April 2012
View articletitled, Abstract 5372: Dendritic-cell based vaccine for advanced pancreatic cancer: A report of 39 cases treated in Seren Clinic Nagoya
Journal Articles

Abstract 1804: Immuno-chemoradiotherapy for oral cancer: Augmentation of OK-432-induced anti-tumor immunity by tegafur and radiation

Masato Okamoto, Tomoyuki Tano, Kan Shin, Sato Mitsunobu
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 1804.
https://doi.org/10.1158/1538-7445.AM2011-1804
Published: 15 April 2011
View articletitled, Abstract 1804: Immuno-chemoradiotherapy for oral cancer: Augmentation of OK-432-induced anti-tumor immunity by tegafur and radiation
Journal Articles

Abstract 4753: Anti-tumor effect of dendritic cell-based immunotherapy in combination with chemotherapy in the patients with advanced colorectal cancer

Shinichiro Akiyama, Jun Tsukada, Takeshi Tomoda, Hiroyuki Abe, Masato Okamoto
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 4753.
https://doi.org/10.1158/1538-7445.AM10-4753
Published: 15 April 2010
View articletitled, Abstract 4753: Anti-tumor effect of dendritic cell-based immunotherapy in combination with chemotherapy in the patients with advanced colorectal cancer
Journal Articles

Abstract #737: Anti-tumor effect of dendritic cell-based immunotherapy in combination with gemcitabine/S-1 in the patients with advanced pancreatic cancer

Masato Okamoto
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 737.
Published: 01 May 2009
View articletitled, Abstract #737: Anti-tumor effect of dendritic cell-based immunotherapy in combination with gemcitabine/S-1 in the patients with advanced pancreatic cancer
Journal Articles

Induction of helper T-cell 1-dominant state by an immunotherapeutic agent OK-432, 5-fluorouracil and radiation via suppressor of cytokine signaling -1 and -3

Tetsuya Oshikawa, Jun Tsukada, Yuichiro Yazaki, Masato Okamoto
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 953.
Published: 01 May 2007
View articletitled, Induction of helper T-cell 1-dominant state by an immunotherapeutic agent OK-432, 5-fluorouracil and radiation via suppressor of cytokine signaling -1 and -3
Journal Articles

Anti-tumor effect of local administration of dendritic cells in combination with stereotactic radiotherapy against advanced colorectal cancer

Masato Okamoto, Jun Tsukada, Tetsuya Oshikawa, Yuichiro Yazaki
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 1851.
Published: 01 May 2007
View articletitled, Anti-tumor effect of local administration of dendritic cells in combination with stereotactic radiotherapy against advanced colorectal cancer
Journal Articles

Induction of helper T-cell 1-dominant state by an immunotherapeutic agent OK-432, 5-fluorouracil and radiation: Involvement of suppressor of cytokine signaling −1 and −3.

Masato Okamoto, Tetsuya Oshikawa, Tomoyuki Tano, Sharif U. Ahmed, Akiko Sasai, Shin Kan, Mitsunobu Sato
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 1308.
Published: 15 April 2006
View articletitled, Induction of helper T-cell 1-dominant state by an immunotherapeutic agent OK-432, 5-fluorouracil and radiation: Involvement of suppressor of cytokine signaling −1 and −3.
Journal Articles

Expression of Toll-Like Receptor 4 on Dendritic Cells Is Significant for Anticancer Effect of Dendritic Cell-Based Immunotherapy in Combination with an Active Component of OK-432, a Streptococcal Preparation

Masato Okamoto, Sachiko Furuichi, Yasuhiko Nishioka, Tetsuya Oshikawa, Tomoyuki Tano, Sharif Uddin Ahmed, Kiyoshi Takeda, Shizuo Akira, Yoshiki Ryoma, Yoichiro Moriya, Motoo Saito, Saburo Sone, Mitsunobu Sato
Journal: Cancer Research
Cancer Res (2004) 64 (15): 5461–5470.
https://doi.org/10.1158/0008-5472.CAN-03-4005
Published: 02 August 2004
View articletitled, Expression of Toll-Like Receptor 4 on Dendritic Cells Is Significant for Anticancer Effect of Dendritic Cell-Based Immunotherapy in Combination with an Active Component of OK-432, a Streptococcal Preparation
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Journal Articles

Therapeutic effect of streptococcal agent OK-432 via toll-like receptor (TLR)4/MD-2 in the therapy for oral squamous cell carcinoma by UFT and OK-432 in combination with radiotherapy.

Mitsunobu Sato, Masato Okamoto, Takashi Bando, Koji Harada, Hideo Yoshida, Tomoyuki Tano, Sachiko Furuichi, Tetsuya Oshikawa, Sharif U. Ahmed, Yoichiro Moriya, Yoshiki Ryoma, Motoo Saito
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 506.
Published: 01 April 2004
View articletitled, Therapeutic effect of streptococcal agent OK-432 via toll-like receptor (TLR)4/MD-2 in the therapy for oral squamous cell carcinoma by UFT and OK-432 in combination with radiotherapy.
Journal Articles

Involvement of Toll-like receptor 4 in the anti-tumor effect of intratumoral administration of dendritic cells followed by an active component of a streptococcal agent OK-432 against tumor-bearing mice

Masato Okamoto, Sachiko Furuichi, Tetsuya Oshikawa, Tomoyuki Tano, Sharif U. Ahmed, Yoichiro Moriya, Yoshiki Ryoma, Motoo Saito, Mitsunobu Sato
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 1089–1090.
Published: 01 April 2004
View articletitled, Involvement of Toll-like receptor 4 in the anti-tumor effect of intratumoral administration of dendritic cells followed by an active component of a streptococcal agent OK-432 against tumor-bearing mice
Journal Articles

Interleukin-6 as a Paracrine and Autocrine Growth Factor in Human Prostatic Carcinoma Cells in Vitro

Masato Okamoto, Chung Lee, Ryoichi Oyasu
Journal: Cancer Research
Cancer Res (1997) 57 (1): 141–146.
Published: 01 January 1997
View articletitled, Interleukin-6 as a Paracrine and Autocrine Growth Factor in Human Prostatic Carcinoma Cells in Vitro
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Journal Articles

Transformation in Vitro of a Nontumorigenic Rat Urothelial Cell Line by Hydrogen Peroxide

Masato Okamoto, Koji Kawai, Catherine A. Reznikoff, Ryoichi Oyasu
Journal: Cancer Research
Cancer Res (1996) 56 (20): 4649–4653.
Published: 01 October 1996
View articletitled, Transformation in Vitro of a Nontumorigenic Rat Urothelial Cell Line by Hydrogen Peroxide
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Journal Articles

Enhancement of Transformation in Vitro of a Nontumorigenic Rat Urothelial Cell Line by Interleukin 6

Masato Okamoto, Hitoshi Kawamata, Koji Kawai, Ryoichi Oyasu
Journal: Cancer Research
Cancer Res (1995) 55 (20): 4581–4585.
Published: 01 October 1995
View articletitled, Enhancement of Transformation in Vitro of a Nontumorigenic Rat Urothelial Cell Line by Interleukin 6
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