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Masao Omata
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Journal Articles

Abstract A85: The exploration of novel strategy for treatment of pancreactic ductal adenocarcinoma targeting tumor microenvironment.

Motohisa Tada, Masao Omata, Harold L. Moses, Osamu Yokosuka, Hideaki Ijichi, Koji Miyabayashi, Yoshinari Asaoka, Dai Mohri, Tsuneo Ikenoue, Rintarou Mikata, Takeshi Ishihara, Fumihiko Kanai
Journal: Cancer Research
Cancer Res (2012) 72 (14_Supplement): A85.
https://doi.org/10.1158/1538-7445.PANCA2012-A85
Published: 03 April 2014
View article titled, Abstract A85: The exploration of novel strategy for treatment of pancreactic ductal adenocarcinoma targeting tumor microenvironment.
Journal Articles

Abstract B27: Erlotinib prolongs survival in pancreatic cancer by blocking gemcitabine-induced mitogen-activated protein kinase signal.

Koji Miyabayashi, Hiroyuki Isayama, Masao Omata, Harold L. Moses, Kazuhiko Koike, Hideaki Ijichi, Dai Mohri, Motohisa Tada, Keisuke Yamamoto, Yoshinari Asaoka, Tsuneo Ikenoue, Keisuke Tateishi, Yousuke Nakai
Journal: Cancer Research
Cancer Res (2012) 72 (14_Supplement): B27.
https://doi.org/10.1158/1538-7445.PANCA2012-B27
Published: 03 April 2014
View article titled, Abstract B27: Erlotinib prolongs survival in pancreatic cancer by blocking gemcitabine-induced mitogen-activated protein kinase signal.
Journal Articles

Abstract A69: The novel strategy for treatment of pancreactic ductal adenocarcinoma targeting tumor microenvironment.

Motohisa Tada, Hideaki Ijichi, Koji Miyabayashi, Yoshinari Asaoka, Dai Mohri, Tsuneo Ikenoue, Rintarou Mikata, Takeshi Ishihara, Fumihiko Kanai, Masao Omata, Harold L. Moses, Osamu Yokosuka
Journal: Cancer Research
Cancer Res (2013) 73 (1_Supplement): A69.
https://doi.org/10.1158/1538-7445.TUMIMM2012-A69
Published: 02 April 2014
View article titled, Abstract A69: The novel strategy for treatment of pancreactic ductal adenocarcinoma targeting tumor microenvironment.
Journal Articles

Abstract 2982: Reduced expression of histone demethylase KDM6B promotes pancreatic cancer progression through downregulation of C/EBPα.

Keisuke Yamamoto, Keisuke Tateishi, Yotaro Kudo, Miwako Kakiuchi, Shinzo Yamamoto, Koji Miyabayashi, Yoshinari Asaoka, Hideaki Ijichi, Masao Omata, Kazuhiko Koike
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 2982.
https://doi.org/10.1158/1538-7445.AM2013-2982
Published: 15 April 2013
View article titled, Abstract 2982: Reduced expression of histone demethylase KDM6B promotes pancreatic cancer progression through downregulation of C/EBPα.
Journal Articles

Erlotinib Prolongs Survival in Pancreatic Cancer by Blocking Gemcitabine-Induced MAPK Signals

Koji Miyabayashi, Hideaki Ijichi, Dai Mohri, Motohisa Tada, Keisuke Yamamoto, Yoshinari Asaoka, Tsuneo Ikenoue, Keisuke Tateishi, Yousuke Nakai, Hiroyuki Isayama, Yasuyuki Morishita, Masao Omata, Harold L. Moses, Kazuhiko Koike
Journal: Cancer Research
Cancer Res (2013) 73 (7): 2221–2234.
https://doi.org/10.1158/0008-5472.CAN-12-1453
Published: 02 April 2013
View article titled, Erlotinib Prolongs Survival in Pancreatic Cancer by Blocking Gemcitabine-Induced MAPK Signals
Open the PDF for Erlotinib Prolongs Survival in Pancreatic Cancer by Blocking Gemcitabine-Induced MAPK Signals in another window
Includes: Supplementary data
Journal Articles

Abstract 851: Epidermal growth factor receptor inhibitor erlotinib prolongs survival in Kras-mutant pancreatic ductal adenocarcinoma by inhibiting gemcitabine-induced mitogen activated protein kinase signaling activation

Koji Miyabayashi, Hideaki Ijichi, Dai Mohri, Motohisa Tada, Keisuke Yamamoto, Yoshinari Asaoka, Tsuneo Ikenoue, Yousuke Nakai, Hiroyuki Isayama, Masao Omata, Harold Moses, Kazuhiko Koike
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 851.
https://doi.org/10.1158/1538-7445.AM2012-851
Published: 15 April 2012
View article titled, Abstract 851: Epidermal growth factor receptor inhibitor erlotinib prolongs survival in <em>Kras</em>-mutant pancreatic ductal adenocarcinoma by inhibiting gemcitabine-induced mitogen activated protein kinase signaling activation
Journal Articles

Abstract 4383: Targeting tumor microenvironment with gemcitabine is useful for the treatment of pancreatic ductal adenocarcinoma

Motohisa Tada, Hideaki Ijichi, Koji Miyabayashi, Yoshinari Asaoka, Dai Mohri, Tsuneo Ikenoue, Rintarou Mikata, Katsunobu Tawada, Takeshi Ishihara, Fumihiko Kanai, Fumio Imazeki, Masao Omata, Harold L. Moses, Osamu Yokosuka
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 4383.
https://doi.org/10.1158/1538-7445.AM2012-4383
Published: 15 April 2012
View article titled, Abstract 4383: Targeting tumor microenvironment with gemcitabine is useful for the treatment of pancreatic ductal adenocarcinoma
Journal Articles

Abstract 3978: DDX20, a suppressor of hepatocarcinogenesis, controls NF-κB activity through regulating the function of miRNA-22 and miRNA-140-3p targeting transcriptional coactivators

Akemi Takata, Motoyuki Otsuka, Kentaro Kojima, Takeshi Yoshikawa, Takahiro Kishikawa, Hideaki Ijichi, Yoshihiro Hirata, Keisuke Tateishi, Haruhiko Yoshida, Masao Omata, Kazuhiko Koike
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 3978.
https://doi.org/10.1158/1538-7445.AM2011-3978
Published: 15 April 2011
View article titled, Abstract 3978: DDX20, a suppressor of hepatocarcinogenesis, controls NF-κB activity through regulating the function of miRNA-22 and miRNA-140-3p targeting transcriptional coactivators
Journal Articles

Abstract 3133: Apoptosis signal-regulating kinase 1 and cyclin D1 compose a positive feedback loop contributing to tumor growth in gastric cancer

Yoku Hayakawa, Yoshihiro Hirata, Hayato Nakagawa, Kei Sakamoto, Wachiko Nakata, Hiroto Kinoshita, Ryota Takahashi, Kohsuke Sakitani, Yohko Hikiba, Ayako Yanai, Masao Akanuma, Kohsuke Takeda, Hidenori Ichijo, Masao Omata, Shin Maeda, Kazuhiko Koike
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 3133.
https://doi.org/10.1158/1538-7445.AM2011-3133
Published: 15 April 2011
View article titled, Abstract 3133: Apoptosis signal-regulating kinase 1 and cyclin D1 compose a positive feedback loop contributing to tumor growth in gastric cancer
Journal Articles

Abstract 3292: The exploration of novel strategy for treatment of pancreactic cancer using genetically engineered mice

Motohisa Tada, Hideaki Ijichi, Koji Miyabayashi, Dai Mohri, Yoshinari Asaoka, Tsuneo Ikenoue, Keisuke Tateishi, Rintarou Mikata, Takeshi Ishihara, Fumihiko Kanai, Fumio Imazeki, Harold L. Moses, Masao Omata, Osamu Yokosuka
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 3292.
https://doi.org/10.1158/1538-7445.AM2011-3292
Published: 15 April 2011
View article titled, Abstract 3292: The exploration of novel strategy for treatment of pancreactic cancer using genetically engineered mice
Journal Articles

Abstract 2381: Preclinical molecular targeting therapy of pancreatic cancer using a genetically engineered mouse model

Koji Miyabayashi, Hideaki Ijichi, Dai Mohri, Motohisa Tada, Yoshinari Asaoka, Tsuneo Ikenoue, Masao Omata, Harold L. Moses, Kazuhiko Koike
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 2381.
https://doi.org/10.1158/1538-7445.AM2011-2381
Published: 15 April 2011
View article titled, Abstract 2381: Preclinical molecular targeting therapy of pancreatic cancer using a genetically engineered mouse model
Journal Articles

Abstract 544: Blockade of CXC chemokines/CXCR2 axis in the tumor microenvironment as a potent therapeutic strategy for pancreatic ductal adenocarcinoma

Hideaki Ijichi, Motohisa Tada, Koji Miyabayashi, Dai Mohri, Yoshinari Asaoka, Keisuke Tateishi, Tsuneo Ikenoue, Masao Omata, Kazuhiko Koike, Harold L. Moses
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 544.
https://doi.org/10.1158/1538-7445.AM2011-544
Published: 15 April 2011
View article titled, Abstract 544: Blockade of CXC chemokines/CXCR2 axis in the tumor microenvironment as a potent therapeutic strategy for pancreatic ductal adenocarcinoma
Journal Articles

Abstract 2065: DDX20 deficiency enhances NF-κB by impairing NF-κB suppressive-microRNA function and leads to hepatocarcinogenesis

Akemi Takata, Motoyuki Otsuka, Yotaro Kudo, Kentaro Kojima, Shin Maeda, Keisuke Tateishi, Tsuneo Ikenoue, Hideaki Ijichi, Yoshihiro Hirata, Haruhiko Yoshida, Masao Omata, Kazuhiko Koike
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 2065.
https://doi.org/10.1158/1538-7445.AM10-2065
Published: 15 April 2010
View article titled, Abstract 2065: DDX20 deficiency enhances NF-κB by impairing NF-κB suppressive-microRNA function and leads to hepatocarcinogenesis
Journal Articles

Abstract 2259: Blockade of CXC chemokines/CXCR2 axis inhibits pancreatic ductal adenocarcinoma progression through anti-angiogenesis

Hideaki Ijichi, Motohisa Tada, Koji Miyabayashi, Mitsuho Imai, Dai Mohri, Yoshinari Asaoka, Tsuneo Ikenoue, Keisuke Tateishi, Masao Omata, Harold L. Moses
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 2259.
https://doi.org/10.1158/1538-7445.AM10-2259
Published: 15 April 2010
View article titled, Abstract 2259: Blockade of CXC chemokines/CXCR2 axis inhibits pancreatic ductal adenocarcinoma progression through anti-angiogenesis
Journal Articles

Abstract 1184: Prognostic significance of genetic alterations detected by high-density single nucleotide polymorphism (SNP) array in gastrointestinal cancer

Motohisa Tada, Fumihiko Kanai, Yoshinari Asaoka, Yasuo Tanaka, Keisuke Tateishi, Hideaki Ijichi, Miki Ohta, Motoko Seto, Masashi Sanada, Yasuhito Nannya, Fumio Imazeki, Osamu Yokosuka, Seishi Ogawa, Masao Omata
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 1184.
https://doi.org/10.1158/1538-7445.AM10-1184
Published: 15 April 2010
View article titled, Abstract 1184: Prognostic significance of genetic alterations detected by high-density single nucleotide polymorphism (SNP) array in gastrointestinal cancer
Journal Articles

Abstract #1090: Tumor-stromal interaction in pancreatic ductal adenocarcinoma in mice: As a possible therapeutic target for human pancreatic cancer

Hideaki Ijichi, Motohisa Tada, Christopher Wright, Harold Moses, Masao Omata
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 1090.
Published: 01 May 2009
View article titled, Abstract #1090: Tumor-stromal interaction in pancreatic ductal adenocarcinoma in mice: As a possible therapeutic target for human pancreatic cancer
Journal Articles

Abstract #1794: The angiogenesis inhibitor axitinib prolonged overall survival of genetically engineered mouse bearing pancreatic ductal adenocarcinoma

Motohisa Tada, Hideaki Ijichi, Fumihiko Kanai, Tsuneo Ikenoue, Yasuo Tanaka, Miki Ohta, Yoshinari Asaoka, Motoko Seto, Dai Mohri, Koji Miyabayashi, Osamu Yokosuka, Harold Moses, Masao Omata
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 1794.
Published: 01 May 2009
View article titled, Abstract #1794: The angiogenesis inhibitor axitinib prolonged overall survival of genetically engineered mouse bearing pancreatic ductal adenocarcinoma
Journal Articles

c-Jun NH2-Terminal Kinase 1 Is a Critical Regulator for the Development of Gastric Cancer in Mice

Wataru Shibata, Shin Maeda, Yohko Hikiba, Ayako Yanai, Kei Sakamoto, Hayato Nakagawa, Keiji Ogura, Michael Karin, Masao Omata
Journal: Cancer Research
Cancer Res (2008) 68 (13): 5031–5039.
https://doi.org/10.1158/0008-5472.CAN-07-6332
Published: 01 July 2008
View article titled, c-Jun NH<sub>2</sub>-Terminal Kinase 1 Is a Critical Regulator for the Development of Gastric Cancer in Mice
Open the PDF for c-Jun NH<sub>2</sub>-Terminal Kinase 1 Is a Critical Regulator for the Development of Gastric Cancer in Mice in another window
Includes: Supplementary data
Journal Articles

Comprehensive analysis of allelic imbalance by using high-density single nucleotide polymorphism (SNP) array in gastric cancer

Motohisa Tada, Fumihiko Kanai, Yasuo Tanaka, Keisuke Tateishi, Miki Ohta, Yoshinari Asaoka, Motoko Seto, Masashi Sanada, Yasuhito Nannya, Takao Kawabe, Osamu Yokosuka, Seishi Ogawa, Masao Omata
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 1803.
Published: 01 May 2008
View article titled, Comprehensive analysis of allelic imbalance by using high-density single nucleotide polymorphism (SNP) array in gastric cancer
Journal Articles

Genome-wide analysis of allelic imbalance by using high-density single nucleotide polymorphism (SNP) array in colorectal cancer

Motohisa Tada, Fumihiko Kanai, Yasuo Tanaka, Keisuke Tateishi, Miki Ohta, Yoshinari Asaoka, Motoko Seto, Masashi Sanada, Yasuhito Nannya, Takao Kawabe, Osamu Yokosuka, Seishi Ogawa, Masao Omata
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 5508.
Published: 01 May 2008
View article titled, Genome-wide analysis of allelic imbalance by using high-density single nucleotide polymorphism (SNP) array in colorectal cancer