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Journal Articles

Abstract P4-02-09: Evaluation of the Automated Liquid Biopsy-Breast Cancer Methylation (LBx-BCM) Cartridge Assay for Predicting Early Disease Progression and Survival: TBCRC-005 Prospective Trial

Kala Visvanathan, Leslie Cope, Mary Jo Fackler, Michael Considine, Lisa Carey, Andres Forero-Torres, James N. Ingle, Nancy U. Lin, Rita Nanda, Anna Maria Storniolo, Suzana Tulac, Natalie C. Wu, Sudhakar Marla, Neesha R. Venkatesan, Antonio C. Wolff, Saraswati Sukumar

Cancer Res (2023) 83 (5_Supplement): P4-02-09.

https://doi.org/10.1158/1538-7445.SABCS22-P4-02-09

Published: 01 March 2023

View article titled, Abstract P4-02-09: Evaluation of the Automated Liquid Biopsy-Breast Cancer Methylation (LBx-BCM) Cartridge Assay for Predicting Early Disease Progression and Survival: TBCRC-005 Prospective Trial

Journal Articles

Abstract PS4-03: An automated DNA methylation assay for monitoring treatment response in patients with metastatic breast cancer

Mary Jo Fackler, Suzana Tulac, Neesha Venkatesan, Adam J. Aslam, Leslie M. Cope, Jennifer Lehman, Rita Denbow, Jeffrey Reynolds, Morgan Buckley, Bradley M. Downs, Kala Visvanathan, Christopher B. Umbricht, Antonio C. Wolff, Vered Stearns, Edwin W. Lai, Saraswati Sukumar

Cancer Res (2021) 81 (4_Supplement): PS4-03.

https://doi.org/10.1158/1538-7445.SABCS20-PS4-03

Published: 15 February 2021

View article titled, Abstract PS4-03: An automated DNA methylation assay for monitoring treatment response in patients with metastatic breast cancer

Journal Articles

Abstract P4-02-06: Automated molecular diagnosis of suspicious axillary lymph nodes in breast cancer patients

Juanjuan Li, Bradley Downs, Leslie Cope, Xiuyun Zhang, Chuan-gui Song, Kejing Zhang, Yong Han, Mary Jo Fackler, Edwin Lai, Suzana Tulac, Neesha Venkatesan, Timothy Guzman, Chuang Chen, Jingping Yuan, Saraswati Sukumar

Cancer Res (2020) 80 (4_Supplement): P4-02-06.

https://doi.org/10.1158/1538-7445.SABCS19-P4-02-06

Published: 15 February 2020

View article titled, Abstract P4-02-06: Automated molecular diagnosis of suspicious axillary lymph nodes in breast cancer patients

Journal Articles

Abstract 1388: A novel Hyper-Methylation Outlier method for blood biomarker discovery

Bradley M. Downs, Juanjuan Li, Mary Jo Fackler, Antonio C. Wolff, Saraswati Sukumar, Chris B. Umbricht, Leslie M. Cope

Cancer Res (2019) 79 (13_Supplement): 1388.

https://doi.org/10.1158/1538-7445.AM2019-1388

Published: 01 July 2019

View article titled, Abstract 1388: A novel Hyper-Methylation Outlier method for blood biomarker discovery

Journal Articles

Abstract LB-220: An automated breast cancer detection assay for screening in the developing world

Bradley M. Downs, Mary Jo Fackler, Claudia Mercado-Rodriguez, Ashley Cimino-Mathews, Chuang Chen, Jing-Ping Yuan, Eunice van den Berg, Leslie M. Cope, Susan C. Harvey, Syed Z. Ali, Suzana Tulac, Kriszten J. Kocmond, Edwin W. Lai, Brian Rhees, Mike Bates, Saraswati Sukumar

Cancer Res (2018) 78 (13_Supplement): LB-220.

https://doi.org/10.1158/1538-7445.AM2018-LB-220

Published: 01 July 2018

View article titled, Abstract LB-220: An automated breast cancer detection assay for screening in the developing world

Journal Articles

Novel Methylated Biomarkers and a Robust Assay to Detect Circulating Tumor DNA in Metastatic Breast Cancer

Cancer Res (2014) 74 (8): 2160–2170.

https://doi.org/10.1158/0008-5472.CAN-13-3392

Published: 15 April 2014

View article titled, Novel Methylated Biomarkers and a Robust Assay to Detect Circulating Tumor DNA in Metastatic Breast Cancer

Includes: Supplementary data

Journal Articles

Abstract 4797: Global phosphotyrosine survey reveals the evidence of activation of multiple tyrosine kinase signaling pathways in basal-like breast cancer cells

Xinyan Wu, Santosh Renuse, Lily Chen, Raghothama Chaerkady, Min-Sik Kim, Saddiq Zahari, Nandini Sahasrabuddhe, Jun Zhong, Yi Yang, Manoj Kashyap, Arivusudar Marimuthu, Min Ling, Mary Jo Fackler, Vanessa Merino, Zhen Zhang, Saraswati Sukumar, Akhilesh Pandey

Cancer Res (2012) 72 (8_Supplement): 4797.

https://doi.org/10.1158/1538-7445.AM2012-4797

Published: 15 April 2012

View article titled, Abstract 4797: Global phosphotyrosine survey reveals the evidence of activation of multiple tyrosine kinase signaling pathways in basal-like breast cancer cells

Journal Articles

Genome-wide Methylation Analysis Identifies Genes Specific to Breast Cancer Hormone Receptor Status and Risk of Recurrence

Mary Jo Fackler, Christopher B. Umbricht, Danielle Williams, Pedram Argani, Leigh-Ann Cruz, Vanessa F. Merino, Wei Wen Teo, Zhe Zhang, Peng Huang, Kala Visvananthan, Jeffrey Marks, Stephen Ethier, Joe W. Gray, Antonio C. Wolff, Leslie M. Cope, Saraswati Sukumar

Cancer Res (2011) 71 (19): 6195–6207.

https://doi.org/10.1158/0008-5472.CAN-11-1630

Published: 29 September 2011

View article titled, Genome-wide Methylation Analysis Identifies Genes Specific to Breast Cancer Hormone Receptor Status and Risk of Recurrence

Includes: Supplementary data

Journal Articles

Abstract LB-178: Analysis of restored FFPE samples on Infinium methylation arrays

Jennie Le, Dmitry Pokholok, Wei Wen Teo, Brett Barnes, Frank Steemers, Mark Hansen, Jian-Bing Fan, Mostafa Ronaghi, Richard Shen, Alex Helm, Mary Jo Fackler, Chris Umbricht, Marina Bibikova, Saraswati Sukumar, Kevin L. Gunderson

Cancer Res (2011) 71 (8_Supplement): LB-178.

https://doi.org/10.1158/1538-7445.AM2011-LB-178

Published: 15 April 2011

View article titled, Abstract LB-178: Analysis of restored FFPE samples on Infinium methylation arrays

Journal Articles

Epigenetic Inactivation of the Potential Tumor Suppressor Gene FOXF1 in Breast Cancer

Pang-Kuo Lo, Ji Shin Lee, Xiaohui Liang, Liangfeng Han, Tsuyoshi Mori, Mary Jo Fackler, Helen Sadik, Pedram Argani, Tej K. Pandita, Saraswati Sukumar

Cancer Res (2010) 70 (14): 6047–6058.

https://doi.org/10.1158/0008-5472.CAN-10-1576

Published: 14 July 2010

View article titled, Epigenetic Inactivation of the Potential Tumor Suppressor Gene FOXF1 in Breast Cancer

Includes: Supplementary data

Journal Articles

Abstract 4916: MAL, a frequently methylated gene marker for early detection of breast cancer

Yolanda M.N. Hillocks, Pang-Kuo Lo, Wei Wen Teo, Mary Jo Fackler, Saraswati Sukumar

Cancer Res (2010) 70 (8_Supplement): 4916.

https://doi.org/10.1158/1538-7445.AM10-4916

Published: 15 April 2010

View article titled, Abstract 4916: MAL, a frequently methylated gene marker for early detection of breast cancer

Journal Articles

Abstract #507: Forkhead box-F (FOXF) genes that function as novel negative regulators of DNA replication are frequently epigenetically silenced in breast cancer

Pang-Kuo Lo, Ji Shin Lee, Xiaohui Liang, Tsuyoshi Mori, Jyoti Mehrotra, Mary Jo Fackler, Pedram Argani, Saraswati Sukumar

Cancer Res (2009) 69 (9_Supplement): 507.

Published: 01 May 2009

View article titled, Abstract #507: Forkhead box-F (FOXF) genes that function as novel negative regulators of DNA replication are frequently epigenetically silenced in breast cancer

Journal Articles

Methylated genes in breast cancer: Associations with clinical and histopathological features in a high risk cohort

Theresa Swift-Scanlan, Russell Vang, Amanda Blackford, Mary Jo Fackler, Victoria Mock, Saraswati Sukumar

Cancer Res (2008) 68 (9_Supplement): 2650.

Published: 01 May 2008

View article titled, Methylated genes in breast cancer: Associations with clinical and histopathological features in a high risk cohort

Journal Articles

Consistency of quantitative multiplexed - methylation specific PCR (QM-MSP) performed on breast epithelial cells acquired by random periareolar fine needle aspiration (RPFNA) of women at high risk for development of breast cancer.

Bruce Kimler, Mary Jo Fackler, Trina Metheny, Teresa Phillips, Saraswati Sukumar, Carol Fabian

Cancer Res (2007) 67 (9_Supplement): 1683.

Published: 01 May 2007

View article titled, Consistency of quantitative multiplexed - methylation specific PCR (QM-MSP) performed on breast epithelial cells acquired by random periareolar fine needle aspiration (RPFNA) of women at high risk for development of breast cancer.

Journal Articles

In situ analysis of telomere lengths in primary breast tumors and corresponding metastases obtained via rapid autopsy

Alan Meeker, Yuko Konishi, Mary Jo Fackler, Saraswati Sukumar, Pedram Argani

Cancer Res (2007) 67 (9_Supplement): 1222.

Published: 01 May 2007

View article titled, In situ analysis of telomere lengths in primary breast tumors and corresponding metastases obtained via rapid autopsy

Journal Articles

Gene expression and proteomic analysis of fibroblasts from normal and malignant human breast tissues

Jyoti Mehrotra, Dario Kalume, Amanda Blackford, Jeanne Kowalski, Martha Stampfer, Mary Jo Fackler, Akhilesh Pandey, Saraswati Sukumar

Cancer Res (2005) 65 (9_Supplement): 872.

Published: 01 May 2005

View article titled, Gene expression and proteomic analysis of fibroblasts from normal and malignant human breast tissues

Journal Articles

Accurate quantitation of methylation of two genes in one well during QM-MSP via simultaneous use of multiple real-time reporter dyes

Theresa Swift-Scanlan, Mary Jo Fackler, Saraswati Sukumar

Cancer Res (2005) 65 (9_Supplement): 205–206.

Published: 01 May 2005

View article titled, Accurate quantitation of methylation of two genes in one well during QM-MSP via simultaneous use of multiple real-time reporter dyes

Journal Articles

Quantitative Multiplex Methylation-Specific PCR Assay for the Detection of Promoter Hypermethylation in Multiple Genes in Breast Cancer

Mary Jo Fackler, Megan McVeigh, Jyoti Mehrotra, Marissa A. Blum, Julie Lange, Amanda Lapides, Elizabeth Garrett, Pedram Argani, Saraswati Sukumar

Cancer Res (2004) 64 (13): 4442–4452.

https://doi.org/10.1158/0008-5472.CAN-03-3341

Published: 01 July 2004

View article titled, Quantitative Multiplex Methylation-Specific PCR Assay for the Detection of Promoter Hypermethylation in Multiple Genes in Breast Cancer

Journal Articles

Development of quantitative multiplex methylation-specific PCR to sensitively detect cumulative promoter hypermethylation

Mary Jo Fackler, Megan McVeigh, Jyoti Mehrotra, Marissa Blum, Julie Lange, Amanda Lapides, Elizabeth Garrett-Mayer, Pedram Argani, Saraswati Sukumar

Cancer Res (2004) 64 (7_Supplement): 205.

Published: 01 April 2004

View article titled, Development of quantitative multiplex methylation-specific PCR to sensitively detect cumulative promoter hypermethylation

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Abstract P4-02-09: Evaluation of the Automated Liquid Biopsy-Breast Cancer Methylation (LBx-BCM) Cartridge Assay for Predicting Early Disease Progression and Survival: TBCRC-005 Prospective Trial

Abstract PS4-03: An automated DNA methylation assay for monitoring treatment response in patients with metastatic breast cancer

Abstract P4-02-06: Automated molecular diagnosis of suspicious axillary lymph nodes in breast cancer patients

Abstract 1388: A novel Hyper-Methylation Outlier method for blood biomarker discovery

Abstract LB-220: An automated breast cancer detection assay for screening in the developing world

Novel Methylated Biomarkers and a Robust Assay to Detect Circulating Tumor DNA in Metastatic Breast Cancer

Abstract 4797: Global phosphotyrosine survey reveals the evidence of activation of multiple tyrosine kinase signaling pathways in basal-like breast cancer cells

Genome-wide Methylation Analysis Identifies Genes Specific to Breast Cancer Hormone Receptor Status and Risk of Recurrence

Abstract LB-178: Analysis of restored FFPE samples on Infinium methylation arrays

Epigenetic Inactivation of the Potential Tumor Suppressor Gene FOXF1 in Breast Cancer

Abstract 4916: MAL, a frequently methylated gene marker for early detection of breast cancer

Abstract #507: Forkhead box-F (FOXF) genes that function as novel negative regulators of DNA replication are frequently epigenetically silenced in breast cancer

Methylated genes in breast cancer: Associations with clinical and histopathological features in a high risk cohort

Consistency of quantitative multiplexed - methylation specific PCR (QM-MSP) performed on breast epithelial cells acquired by random periareolar fine needle aspiration (RPFNA) of women at high risk for development of breast cancer.

In situ analysis of telomere lengths in primary breast tumors and corresponding metastases obtained via rapid autopsy

Gene expression and proteomic analysis of fibroblasts from normal and malignant human breast tissues

Accurate quantitation of methylation of two genes in one well during QM-MSP via simultaneous use of multiple real-time reporter dyes

Quantitative Multiplex Methylation-Specific PCR Assay for the Detection of Promoter Hypermethylation in Multiple Genes in Breast Cancer

Development of quantitative multiplex methylation-specific PCR to sensitively detect cumulative promoter hypermethylation

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