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Journal Articles

Structural Basis for Induction of Peripheral Neuropathy by Microtubule-Targeting Cancer Drugs

Jennifer A. Smith, Barbara S. Slusher, Krystyna M. Wozniak, Mohamed H. Farah, Gregoriy Smiyun, Leslie Wilson, Stuart Feinstein, Mary Ann Jordan

Cancer Res (2016) 76 (17): 5115–5123.

https://doi.org/10.1158/0008-5472.CAN-15-3116

Published: 31 August 2016

View articletitled, Structural Basis for Induction of Peripheral Neuropathy by Microtubule-Targeting Cancer Drugs

Journal Articles

Abstract 1666: Increased sensitivity of βIII tubulin-containing microtubules to cabazitaxel compared with docetaxel: A possible role of βIII tubulin in specifying good efficacy of cabazitaxel for docetaxel-resistant tumors

Leslie Wilson, Olga Azarenko, Gregoriy Smiyun, Herbert Miller, Mary Ann Jordan

Cancer Res (2015) 75 (15_Supplement): 1666.

https://doi.org/10.1158/1538-7445.AM2015-1666

Published: 01 August 2015

View articletitled, Abstract 1666: Increased sensitivity of βIII tubulin-containing microtubules to cabazitaxel compared with docetaxel: A possible role of βIII tubulin in specifying good efficacy of cabazitaxel for docetaxel-resistant tumors

Journal Articles

Abstract 5503: Microtubule-targeting agents induce differential myelinated axon degeneration in a mouse model of peripheral neuropathy

Brett M. Cook, Sarah J. Benbow, Krystyna M. Wozniak, Barbara S. Slusher, Bruce A. Littlefield, Leslie Wilson, Stuart C. Feinstein, Mary Ann Jordan

Cancer Res (2014) 74 (19_Supplement): 5503.

https://doi.org/10.1158/1538-7445.AM2014-5503

Published: 01 October 2014

View articletitled, Abstract 5503: Microtubule-targeting agents induce differential myelinated axon degeneration in a mouse model of peripheral neuropathy

Journal Articles

Abstract 5294: Inhibition of mitochondrial transport in neuronal cells by microtubule-targeting drugs eribulin, ixabepilone, paclitaxel, and vincristine

Jennifer A. Smith, Gregoriy Smiyun, Leslie Wilson, Stuart Feinstein, Mary Ann Jordan

Cancer Res (2014) 74 (19_Supplement): 5294.

https://doi.org/10.1158/1538-7445.AM2014-5294

Published: 01 October 2014

View articletitled, Abstract 5294: Inhibition of mitochondrial transport in neuronal cells by microtubule-targeting drugs eribulin, ixabepilone, paclitaxel, and vincristine

Journal Articles

Abstract 772: Effects of natural products on proliferation of human breast cancer cells induced by estrogen or PhIP, a heterocyclic amine compound derived from cooked meat

Choong Jae Lee, Mi Nam Lee, Hyun Jae Lee, Su Yel Lee, Jeong Ho Seok, Mary Ann Jordan, Leslie Wilson

Cancer Res (2010) 70 (8_Supplement): 772.

https://doi.org/10.1158/1538-7445.AM10-772

Published: 15 April 2010

View articletitled, Abstract 772: Effects of natural products on proliferation of human breast cancer cells induced by estrogen or PhIP, a heterocyclic amine compound derived from cooked meat

Journal Articles

Abstract #2701: Effects of paeoniflorin, baicalein, hesperidin and oleanolic acid on human breast and prostate cancer cells

Choong Jae Lee, Mary Ann Jordan, Leslie Wilson, Su Yel Lee, Mi Nam Lee

Cancer Res (2009) 69 (9_Supplement): 2701.

Published: 01 May 2009

View articletitled, Abstract #2701: Effects of paeoniflorin, baicalein, hesperidin and oleanolic acid on human breast and prostate cancer cells

Journal Articles

Abstract #5560: Differential effects of \#946;III-tubulin on drug-induced microtubule dynamics and mitotic arrest

Pei Pei Gan, Kathy Kamath, Mary Ann Jordan, Maria Kavallaris

Cancer Res (2009) 69 (9_Supplement): 5560.

Published: 01 May 2009

View articletitled, Abstract #5560: Differential effects of \#946;III-tubulin on drug-induced microtubule dynamics and mitotic arrest

Journal Articles

Antibody-maytansinoid conjugates affect microtubule morphology and suppress microtubule dynamics in live cells

Emin Oroudjev, Manu Lopus, Leslie Wilson, Charlene Audette, Carmela Provenzano, Hans Erickson, Yelena Kovtun, Ravi Chari, Mary Ann Jordan

Cancer Res (2008) 68 (9_Supplement): 1403.

Published: 01 May 2008

View articletitled, Antibody-maytansinoid conjugates affect microtubule morphology and suppress microtubule dynamics in live cells

Journal Articles

Eribulin (E7389) binds to 13 saturable sites at microtubule ends to inhibit microtubule dynamics

Jennifer Smith, Leslie Wilson, Xiaojie Zhu, Bryan Lewis, Bruce Littlefield, Mary Ann Jordan

Cancer Res (2008) 68 (9_Supplement): 1408.

Published: 01 May 2008

View articletitled, Eribulin (E7389) binds to 13 saturable sites at microtubule ends to inhibit microtubule dynamics

Journal Articles

Maytansine derivatives and metabolites of antibody-maytansinoid conjugates inhibit microtubule polymerization and strongly suppress microtubule dynamics

Manu Lopus, Emin Oroudjev, Leslie Wilson, Sharon Wilhelm, Wayne Widdison, Ravi Chari, Mary Ann Jordan

Cancer Res (2008) 68 (9_Supplement): 1406.

Published: 01 May 2008

View articletitled, Maytansine derivatives and metabolites of antibody-maytansinoid conjugates inhibit microtubule polymerization and strongly suppress microtubule dynamics

Journal Articles

Effects of Tetramethoxystilbene on Hormone-Resistant Breast Cancer Cells: Biological and Biochemical Mechanisms of Action

Hoyong Park, Sarah E. Aiyar, Ping Fan, Jiping Wang, Wei Yue, Tatiana Okouneva, Corey Cox, Mary Ann Jordan, Laurence Demers, Hyungjun Cho, Sanghee Kim, Robert X.-D. Song, Richard J. Santen

Cancer Res (2007) 67 (12): 5717–5726.

https://doi.org/10.1158/0008-5472.CAN-07-0056

Published: 15 June 2007

View articletitled, Effects of Tetramethoxystilbene on Hormone-Resistant Breast Cancer Cells: Biological and Biochemical Mechanisms of Action

Includes: Supplementary data

Journal Articles

Mechanism of Action of the Microtubule-Targeted Antimitotic Depsipeptide Tasidotin (Formerly ILX651) and Its Major Metabolite Tasidotin C-Carboxylate

Anasuya Ray, Tatiana Okouneva, Tapas Manna, Herbert P. Miller, Steven Schmid, Larry Arthaud, Richard Luduena, Mary Ann Jordan, Leslie Wilson

Cancer Res (2007) 67 (8): 3767–3776.

https://doi.org/10.1158/0008-5472.CAN-06-3065

Published: 17 April 2007

View articletitled, Mechanism of Action of the Microtubule-Targeted Antimitotic Depsipeptide Tasidotin (Formerly ILX651) and Its Major Metabolite Tasidotin C-Carboxylate

Journal Articles

Effects of stably altered stathmin expression on microtubule dynamic instability in breast cancer cells

Chitose Nakao, Elizabeth Alli, William N. Hait, Leslie Wilson, Mary Ann Jordan

Cancer Res (2006) 66 (8_Supplement): 756.

Published: 15 April 2006

View articletitled, Effects of stably altered stathmin expression on microtubule dynamic instability in breast cancer cells

Journal Articles

Impaired taxane- and epothilone-driven tubulin polymerization in a non-MDR1 taxane-resistant MCF-7 breast cancer variant with reduced MAP4 and elevated MAP Tau content

George E. Duran, Mary Ann Jordan, Branimir I. Sikic

Cancer Res (2006) 66 (8_Supplement): 883.

Published: 15 April 2006

View articletitled, Impaired taxane- and epothilone-driven tubulin polymerization in a non-MDR1 taxane-resistant MCF-7 breast cancer variant with reduced MAP4 and elevated MAP Tau content

Journal Articles

βIII tubulin confers paclitaxel resistance by reducing paclitaxel’s effects on microtubule dynamics

Kathryn V. L. Kamath, Leslie Wilson, Fernando Cabral, Mary Ann Jordan

Cancer Res (2005) 65 (9_Supplement): 775.

Published: 01 May 2005

View articletitled, βIII tubulin confers paclitaxel resistance by reducing paclitaxel’s effects on microtubule dynamics

Journal Articles

NPI-2358, a novel tumor vascular disrupting agent

Benjamin Nicholson, Jamie Bishop, Yoshio Hayashi, Mary Ann Jordan, Leslie Wilson, Yoshiaki Kiso, Per Borgström, Michael A. Palladino, Saskia T. C. Neuteboom, G. Kenneth Lloyd

Cancer Res (2005) 65 (9_Supplement): 808.

Published: 01 May 2005

View articletitled, NPI-2358, a novel tumor vascular disrupting agent

Journal Articles

Antiangiogenic Concentrations of Paclitaxel Induce an Increase in Microtubule Dynamics in Endothelial Cells but Not in Cancer Cells

Eddy Pasquier, Stéphane Honore, Bertrand Pourroy, Mary Ann Jordan, Maxime Lehmann, Claudette Briand, Diane Braguer

Cancer Res (2005) 65 (6): 2433–2440.

https://doi.org/10.1158/0008-5472.CAN-04-2624

Published: 21 March 2005

View articletitled, Antiangiogenic Concentrations of Paclitaxel Induce an Increase in Microtubule Dynamics in Endothelial Cells but Not in Cancer Cells

Journal Articles

Synergistic Suppression of Microtubule Dynamics by Discodermolide and Paclitaxel in Non-Small Cell Lung Carcinoma Cells

Stéphane Honore, Kathy Kamath, Diane Braguer, Susan Band Horwitz, Leslie Wilson, Claudette Briand, Mary Ann Jordan

Cancer Res (2004) 64 (14): 4957–4964.

https://doi.org/10.1158/0008-5472.CAN-04-0693

Published: 15 July 2004

View articletitled, Synergistic Suppression of Microtubule Dynamics by Discodermolide and Paclitaxel in Non-Small Cell Lung Carcinoma Cells

Includes: Supplementary data

Journal Articles

E7389 and ER-076349, synthetic halichondrin B analogs, suppress centromere dynamics in concert with mitotic block

Tatiana Okouneva, Leslie Wilson, Bruce A. Littlefield, Mary Ann Jordan

Cancer Res (2004) 64 (7_Supplement): 1255.

Published: 01 April 2004

View articletitled, E7389 and ER-076349, synthetic halichondrin B analogs, suppress centromere dynamics in concert with mitotic block

Journal Articles

The unusual mechanism of action of the microtubule targeted drug curacin A

Amy L. Shertzer, Horacio Vall, Mary Ann Jordan, William Gerwick, Leslie Wilson

Cancer Res (2004) 64 (7_Supplement): 1249.

Published: 01 April 2004

View articletitled, The unusual mechanism of action of the microtubule targeted drug curacin A

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Structural Basis for Induction of Peripheral Neuropathy by Microtubule-Targeting Cancer Drugs

Abstract 1666: Increased sensitivity of βIII tubulin-containing microtubules to cabazitaxel compared with docetaxel: A possible role of βIII tubulin in specifying good efficacy of cabazitaxel for docetaxel-resistant tumors

Abstract 5503: Microtubule-targeting agents induce differential myelinated axon degeneration in a mouse model of peripheral neuropathy

Abstract 5294: Inhibition of mitochondrial transport in neuronal cells by microtubule-targeting drugs eribulin, ixabepilone, paclitaxel, and vincristine

Abstract 772: Effects of natural products on proliferation of human breast cancer cells induced by estrogen or PhIP, a heterocyclic amine compound derived from cooked meat

Abstract #2701: Effects of paeoniflorin, baicalein, hesperidin and oleanolic acid on human breast and prostate cancer cells

Abstract #5560: Differential effects of \#946;III-tubulin on drug-induced microtubule dynamics and mitotic arrest

Antibody-maytansinoid conjugates affect microtubule morphology and suppress microtubule dynamics in live cells

Eribulin (E7389) binds to 13 saturable sites at microtubule ends to inhibit microtubule dynamics

Maytansine derivatives and metabolites of antibody-maytansinoid conjugates inhibit microtubule polymerization and strongly suppress microtubule dynamics

Effects of Tetramethoxystilbene on Hormone-Resistant Breast Cancer Cells: Biological and Biochemical Mechanisms of Action

Mechanism of Action of the Microtubule-Targeted Antimitotic Depsipeptide Tasidotin (Formerly ILX651) and Its Major Metabolite Tasidotin C-Carboxylate

Effects of stably altered stathmin expression on microtubule dynamic instability in breast cancer cells

Impaired taxane- and epothilone-driven tubulin polymerization in a non-MDR1 taxane-resistant MCF-7 breast cancer variant with reduced MAP4 and elevated MAP Tau content

βIII tubulin confers paclitaxel resistance by reducing paclitaxel’s effects on microtubule dynamics

NPI-2358, a novel tumor vascular disrupting agent

Antiangiogenic Concentrations of Paclitaxel Induce an Increase in Microtubule Dynamics in Endothelial Cells but Not in Cancer Cells

Synergistic Suppression of Microtubule Dynamics by Discodermolide and Paclitaxel in Non-Small Cell Lung Carcinoma Cells

E7389 and ER-076349, synthetic halichondrin B analogs, suppress centromere dynamics in concert with mitotic block

The unusual mechanism of action of the microtubule targeted drug curacin A

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