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Journal Articles

Abstract 6248: Inhibiting β-catenin in AML by targeting DDX5

WEI NI, Swati Garg, Fen Zhu, Ellen L. Weisberg, Basudev Chowdhury, Martin Sattler, Amulya Jakkani, Suiyang Liu, Dana M. Sanchez, Lizi Wu, Richard M. Stone, Matthew S. Davids, James D. Griffin

Cancer Res (2023) 83 (7_Supplement): 6248.

https://doi.org/10.1158/1538-7445.AM2023-6248

Published: 04 April 2023

View article titled, Abstract 6248: Inhibiting β-catenin in AML by targeting DDX5

Journal Articles

Abstract 2912: The AP-1 transcription factor JunB promotes multiple myeloma cell proliferation, survival and drug resistance in the bone marrow microenvironment

Fengjuan Fan, Sonia Vallet, Muhammad Hasan Bashari, Mostafa Jarahian, Eugenio Morelli, Dirk Hose, Latifa Bakiri, Claudia Ball, Hanno Glimm, Martin Sattler, Hartmut Goldschmidt, Giovanni Tonon, Pierfrancesco Tassone, Erwin F. Wagner, Dirk Jäger, Klaus Podar

Cancer Res (2016) 76 (14_Supplement): 2912.

https://doi.org/10.1158/1538-7445.AM2016-2912

Published: 15 July 2016

View article titled, Abstract 2912: The AP-1 transcription factor JunB promotes multiple myeloma cell proliferation, survival and drug resistance in the bone marrow microenvironment

Journal Articles

Abstract 3383: JunB/AP-1 controls MM cell proliferation, survival and drug resistance in the bone marrow microenvironment

Fengjuan Fan, Sonia Vallet, Martin Sattler, Giovanni Tonon, Muhammad Hasan Bashari, Latifa Bakiri, Hartmut Goldschmidt, Erwin F. Wagner, Dirk Jaeger, Klaus Podar

Cancer Res (2014) 74 (19_Supplement): 3383.

https://doi.org/10.1158/1538-7445.AM2014-3383

Published: 01 October 2014

View article titled, Abstract 3383: JunB/AP-1 controls MM cell proliferation, survival and drug resistance in the bone marrow microenvironment

Journal Articles

Abstract 1734: Drug- induced generation of Mcl-1^128-350 fragment triggers apoptosis in multiple myeloma cells through upregulation of c-Jun.

Fengjuan Fan, Giovanni Tonon, Martin Sattler, Hartmut Goldschmidt, Joseph Opferman, Kenneth C. Anderson, Dirk Jäger, Klaus Podar

Cancer Res (2013) 73 (8_Supplement): 1734.

https://doi.org/10.1158/1538-7445.AM2013-1734

Published: 15 April 2013

View article titled, Abstract 1734: Drug- induced generation of Mcl-1128-350 fragment triggers apoptosis in multiple myeloma cells through upregulation of c-Jun.

Journal Articles

Targeting Angiogenesis via a c-Myc/Hypoxia-Inducible Factor-1α–Dependent Pathway in Multiple Myeloma

Jing Zhang, Martin Sattler, Giovanni Tonon, Clemens Grabher, Samir Lababidi, Alexander Zimmerhackl, Marc S. Raab, Sonia Vallet, Yiming Zhou, Marie-Astrid Cartron, Teru Hideshima, Yu-Tzu Tai, Dharminder Chauhan, Kenneth C. Anderson, Klaus Podar

Cancer Res (2009) 69 (12): 5082–5090.

https://doi.org/10.1158/0008-5472.CAN-08-4603

Published: 15 June 2009

View article titled, Targeting Angiogenesis via a c-Myc/Hypoxia-Inducible Factor-1α–Dependent Pathway in Multiple Myeloma

Includes: Supplementary data

Journal Articles

Abstract #LB-192: NADPH oxidases are not a major source of reactive oxygen species in myeloid leukemia cells transformed by oncogenic tyrosine kinases but are required for optimal cell growth

Mamatha Reddy, Margret Fernandes, James Griffin, Martin Sattler

Cancer Res (2009) 69 (9_Supplement): LB-192.

Published: 01 May 2009

View article titled, Abstract #LB-192: NADPH oxidases are not a major source of reactive oxygen species in myeloid leukemia cells transformed by oncogenic tyrosine kinases but are required for optimal cell growth

Journal Articles

Abstract #3185: Targeting angiogenesis via a c-Myc/ Hif-1\#945;- dependent pathway in MM

Klaus Podar, Jing Zhang, Giovanni Tonon, Martin Sattler, Clemens Grabher, Samir Lababidi, Alexander Zimmerhackl, Marc Raab, Sonia Vallet, Yiming Zhou, Marie-Astrid Cartron, Yu-Tzu Tai, Dharminder Chauhan, Kenneth Anderson

Cancer Res (2009) 69 (9_Supplement): 3185.

Published: 01 May 2009

View article titled, Abstract #3185: Targeting angiogenesis via a c-Myc/ Hif-1\#945;- dependent pathway in MM

Journal Articles

Abstract #5610: CRLF2 is a proto-oncogene in pre-B acute lymphoblastic leukemia with normal cytogenetics

Akinori Yoda, Michal Bar-Natan, Martin Sattler, Jerome Ritz, David Frank, David Weinstock

Cancer Res (2009) 69 (9_Supplement): 5610.

Published: 01 May 2009

View article titled, Abstract #5610: CRLF2 is a proto-oncogene in pre-B acute lymphoblastic leukemia with normal cytogenetics

Journal Articles

Tyrosine kinase oncogenes in leukemias and myeloproliferative disorders increase the activity of the mutagenic single-strand annealing DNA repair pathway

Margret Rodrigues, Mamatha Reddy, Jeffrey Gonneville, David Weinstock, James Griffin, Martin Sattler

Cancer Res (2008) 68 (9_Supplement): LB-270.

Published: 01 May 2008

View article titled, Tyrosine kinase oncogenes in leukemias and myeloproliferative disorders increase the activity of the mutagenic single-strand annealing DNA repair pathway

Journal Articles

The tyrophostin adaphostin (NSC680410) inhibits multiple myeloma bone marrow angiogenesis in in vitro and in vivo studies

Klaus Podar, Jing Zhang, Marc Raab, Sonia Vallet, Giovanni Tonon, Martin Sattler, Yutaka Ikeda, Teru Hideshima, Dharminder Chauhan, Kenneth Anderson

Cancer Res (2008) 68 (9_Supplement): 5529.

Published: 01 May 2008

View article titled, The tyrophostin adaphostin (NSC680410) inhibits multiple myeloma bone marrow angiogenesis in in vitro and in vivo studies

Journal Articles

Paxillin Is a Target for Somatic Mutations in Lung Cancer: Implications for Cell Growth and Invasion

Cancer Res (2008) 68 (1): 132–142.

https://doi.org/10.1158/0008-5472.CAN-07-1998

Published: 02 January 2008

View article titled, Paxillin Is a Target for Somatic Mutations in Lung Cancer: Implications for Cell Growth and Invasion

Includes: Supplementary data

Journal Articles

Upregulation of c-Jun inhibits proliferation and induces apoptosis via caspase-triggered c-Abl cleavage in human multiple myeloma and other malignancies

Klaus Podar, Marc Raab, Giovanni Tonon, Martin Sattler, Daniela Barila, Jing Zhang, Yu-Tzu Tai, Noopur Raje, Ronald DePinho, Teru Hideshima, Dharminder Chauhan, Kenneth Anderson

Cancer Res (2007) 67 (9_Supplement): 5143.

Published: 01 May 2007

View article titled, Upregulation of c-Jun inhibits proliferation and induces apoptosis via caspase-triggered c-Abl cleavage in human multiple myeloma and other malignancies

Journal Articles

Up-Regulation of c-Jun Inhibits Proliferation and Induces Apoptosis via Caspase-Triggered c-Abl Cleavage in Human Multiple Myeloma

Klaus Podar, Marc S. Raab, Giovanni Tonon, Martin Sattler, Daniela Barilà, Jing Zhang, Yu-Tzu Tai, Hiroshi Yasui, Noopur Raje, Ronald A. DePinho, Teru Hideshima, Dharminder Chauhan, Kenneth C. Anderson

Cancer Res (2007) 67 (4): 1680–1688.

https://doi.org/10.1158/0008-5472.CAN-06-1863

Published: 16 February 2007

View article titled, Up-Regulation of c-Jun Inhibits Proliferation and Induces Apoptosis via Caspase-Triggered c-Abl Cleavage in Human Multiple Myeloma

Includes: Supplementary data

Journal Articles

In vitro and in vivo activity of the VEGF receptor inhibitor PAZOPANIB (GW786034) in Multiple Myeloma: Therapeutic implications.

Klaus Podar, Giovanni Tonon, Dean Abtahi, Laurence P. Catley, Yu-Tzu Tai, Steven Legouill, Hiroshi Yasui, Martin Sattler, Rakesh Kumar, Lini N. Pandite, Teru Hideshima, Dharminder Chauhan, Kenneth C. Anderson

Cancer Res (2006) 66 (8_Supplement): 1330.

Published: 15 April 2006

View article titled, In vitro and in vivo activity of the VEGF receptor inhibitor PAZOPANIB (GW786034) in Multiple Myeloma: Therapeutic implications.

Journal Articles

A novel non-peptide and orally active proteasome inhibitor overcomes bortezomib-resistance in multiple myeloma (MM) cells

Dharminder Chauhan, Laurence Catley, Guilan Li, Martin Sattler, Klaus Podar, Teru Hideshima, Nikhil Munshi, Paul Richardson, Ta-Hsiang Chao, Saskia Neuteboom, Michael Palladino, Kenneth C. Andersn

Cancer Res (2005) 65 (9_Supplement): 1448.

Published: 01 May 2005

View article titled, A novel non-peptide and orally active proteasome inhibitor overcomes bortezomib-resistance in multiple myeloma (MM) cells

Journal Articles

Caveolin-1 Is Required for Vascular Endothelial Growth Factor-Triggered Multiple Myeloma Cell Migration and Is Targeted by Bortezomib

Klaus Podar, Reshma Shringarpure, Yu-Tzu Tai, Melissa Simoncini, Martin Sattler, Kenji Ishitsuka, Paul G. Richardson, Teru Hideshima, Dharminder Chauhan, Kenneth C. Anderson

Cancer Res (2004) 64 (20): 7500–7506.

https://doi.org/10.1158/0008-5472.CAN-04-0124

Published: 15 October 2004

View article titled, Caveolin-1 Is Required for Vascular Endothelial Growth Factor-Triggered Multiple Myeloma Cell Migration and Is Targeted by Bortezomib

Journal Articles

c-MET Mutational Analysis in Small Cell Lung Cancer: Novel Juxtamembrane Domain Mutations Regulating Cytoskeletal Functions

Patrick C. Ma, Takashi Kijima, Gautam Maulik, Edward A. Fox, Martin Sattler, James D. Griffin, Bruce E. Johnson, Ravi Salgia

Cancer Res (2003) 63 (19): 6272–6281.

Published: 14 October 2003

View article titled, c-MET Mutational Analysis in Small Cell Lung Cancer: <subtitle>Novel Juxtamembrane Domain Mutations Regulating Cytoskeletal Functions</subtitle>

Journal Articles

A Novel Small Molecule Met Inhibitor Induces Apoptosis in Cells Transformed by the Oncogenic TPR-MET Tyrosine Kinase

Martin Sattler, Yuri B. Pride, Patrick Ma, Jessica L. Gramlich, Stephanie C. Chu, Laura A. Quinnan, Sheri Shirazian, Congxin Liang, Klaus Podar, James G. Christensen, Ravi Salgia

Cancer Res (2003) 63 (17): 5462–5469.

Published: 18 September 2003

View article titled, A Novel Small Molecule Met Inhibitor Induces Apoptosis in Cells Transformed by the Oncogenic TPR-MET Tyrosine Kinase

Journal Articles

Regulation of Cellular Proliferation, Cytoskeletal Function, and Signal Transduction through CXCR4 and c-Kit in Small Cell Lung Cancer Cells

Takashi Kijima, Gautam Maulik, Patrick C. Ma, Elena V. Tibaldi, Ross E. Turner, Barrett Rollins, Martin Sattler, Bruce E. Johnson, Ravi Salgia

Cancer Res (2002) 62 (21): 6304–6311.

Published: 01 November 2002

View article titled, Regulation of Cellular Proliferation, Cytoskeletal Function, and Signal Transduction through CXCR4 and c-Kit in Small Cell Lung Cancer Cells

NARROW

Abstract 6248: Inhibiting β-catenin in AML by targeting DDX5

Abstract 2912: The AP-1 transcription factor JunB promotes multiple myeloma cell proliferation, survival and drug resistance in the bone marrow microenvironment

Abstract 3383: JunB/AP-1 controls MM cell proliferation, survival and drug resistance in the bone marrow microenvironment

Abstract 1734: Drug- induced generation of Mcl-1^128-350 fragment triggers apoptosis in multiple myeloma cells through upregulation of c-Jun.

Targeting Angiogenesis via a c-Myc/Hypoxia-Inducible Factor-1α–Dependent Pathway in Multiple Myeloma

Abstract #LB-192: NADPH oxidases are not a major source of reactive oxygen species in myeloid leukemia cells transformed by oncogenic tyrosine kinases but are required for optimal cell growth

Abstract #3185: Targeting angiogenesis via a c-Myc/ Hif-1\#945;- dependent pathway in MM

Abstract #5610: CRLF2 is a proto-oncogene in pre-B acute lymphoblastic leukemia with normal cytogenetics

Tyrosine kinase oncogenes in leukemias and myeloproliferative disorders increase the activity of the mutagenic single-strand annealing DNA repair pathway

The tyrophostin adaphostin (NSC680410) inhibits multiple myeloma bone marrow angiogenesis in in vitro and in vivo studies

Paxillin Is a Target for Somatic Mutations in Lung Cancer: Implications for Cell Growth and Invasion

Upregulation of c-Jun inhibits proliferation and induces apoptosis via caspase-triggered c-Abl cleavage in human multiple myeloma and other malignancies

Up-Regulation of c-Jun Inhibits Proliferation and Induces Apoptosis via Caspase-Triggered c-Abl Cleavage in Human Multiple Myeloma

In vitro and in vivo activity of the VEGF receptor inhibitor PAZOPANIB (GW786034) in Multiple Myeloma: Therapeutic implications.

A novel non-peptide and orally active proteasome inhibitor overcomes bortezomib-resistance in multiple myeloma (MM) cells

Caveolin-1 Is Required for Vascular Endothelial Growth Factor-Triggered Multiple Myeloma Cell Migration and Is Targeted by Bortezomib

c-MET Mutational Analysis in Small Cell Lung Cancer: Novel Juxtamembrane Domain Mutations Regulating Cytoskeletal Functions

A Novel Small Molecule Met Inhibitor Induces Apoptosis in Cells Transformed by the Oncogenic TPR-MET Tyrosine Kinase

Regulation of Cellular Proliferation, Cytoskeletal Function, and Signal Transduction through CXCR4 and c-Kit in Small Cell Lung Cancer Cells

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