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Martin Philpott
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Journal Articles

Abstract 4404: BRPF1 inhibition restores chemosensitivity in triple negative breast cancer via ribosomal pathway modulation

Free
Ozlem Yedier Bayram, Ahmet Cingöz, Ebru Yilmaz, Ali Cenk Aksu, Beril Esin, Nareg Pinarbaşi-Degirmenci, Ayşe Derya Cavga, Beyza Dedeoglu, Buse Cevatemre, Hamzah Syed, MArtin Philpott, Adam P. Cribbs, Udo Opperman, Nathan A. Lack, Ceyda Açılan Ayhan, Tamer T. Onder, Tugba Bagci Onder
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 4404.
https://doi.org/10.1158/1538-7445.AM2025-4404
Published: 21 April 2025
View articletitled, Abstract 4404: BRPF1 inhibition restores chemosensitivity in triple negative breast cancer via ribosomal pathway modulation
Journal Articles

Abstract 3025: PRMT5 inhibition reduces viability and stemness of pediatric high grade glioma

Free
Elizabeth J. Brown, Leire Balaguer-Lluna, Adam Cribbs, Martin Philpott, Ángel M. Carcaboso, Gillian Farnie, Alex N. Bullock
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 3025.
https://doi.org/10.1158/1538-7445.AM2021-3025
Published: 01 July 2021
View articletitled, Abstract 3025: PRMT5 inhibition reduces viability and stemness of pediatric high grade glioma
Journal Articles

Inhibition of Histone H3K27 Demethylases Inactivates Brachyury (TBXT) and Promotes Chordoma Cell Death

Available to Purchase
Lucia Cottone, Adam P. Cribbs, Garima Khandelwal, Graham Wells, Lorena Ligammari, Martin Philpott, Anthony Tumber, Patrick Lombard, Edward S. Hookway, Tamas Szommer, Catrine Johansson, Paul E. Brennan, Nischalan Pillay, Richard G. Jenner, Udo Oppermann, Adrienne M. Flanagan
Journal: Cancer Research
Cancer Res (2020) 80 (20): 4540–4551.
https://doi.org/10.1158/0008-5472.CAN-20-1387
Published: 15 October 2020
View articletitled, Inhibition of Histone H3K27 Demethylases Inactivates Brachyury (TBXT) and Promotes Chordoma Cell Death
Open the PDF for Inhibition of Histone H3K27 Demethylases Inactivates Brachyury (TBXT) and Promotes Chordoma Cell Death in another window
Includes: Supplementary data
Journal Articles

Generation of a Selective Small Molecule Inhibitor of the CBP/p300 Bromodomain for Leukemia Therapy

Free
Sarah Picaud, Oleg Fedorov, Angeliki Thanasopoulou, Katharina Leonards, Katherine Jones, Julia Meier, Heidi Olzscha, Octovia Monteiro, Sarah Martin, Martin Philpott, Anthony Tumber, Panagis Filippakopoulos, Clarence Yapp, Christopher Wells, Ka Hing Che, Andrew Bannister, Samuel Robson, Umesh Kumar, Nigel Parr, Kevin Lee, Dave Lugo, Philip Jeffrey, Simon Taylor, Matteo L. Vecellio, Chas Bountra, Paul E. Brennan, Alison O'Mahony, Sharlene Velichko, Susanne Müller, Duncan Hay, Danette L. Daniels, Marjeta Urh, Nicholas B. La Thangue, Tony Kouzarides, Rab Prinjha, Jürg Schwaller, Stefan Knapp
Journal: Cancer Research
Series: Author Choice
Cancer Res (2015) 75 (23): 5106–5119.
https://doi.org/10.1158/0008-5472.CAN-15-0236
Published: 30 November 2015
View articletitled, Generation of a Selective Small Molecule Inhibitor of the CBP/p300 Bromodomain for Leukemia Therapy
Open the PDF for Generation of a Selective Small Molecule Inhibitor of the CBP/p300 Bromodomain for Leukemia Therapy in another window
Includes: Supplementary data
Journal Articles

PFI-1, a Highly Selective Protein Interaction Inhibitor, Targeting BET Bromodomains

Free
Sarah Picaud, David Da Costa, Angeliki Thanasopoulou, Panagis Filippakopoulos, Paul V. Fish, Martin Philpott, Oleg Fedorov, Paul Brennan, Mark E. Bunnage, Dafydd R. Owen, James E. Bradner, Philippe Taniere, Brendan O'Sullivan, Susanne Müller, Juerg Schwaller, Tatjana Stankovic, Stefan Knapp
Journal: Cancer Research
Series: Author Choice
Cancer Res (2013) 73 (11): 3336–3346.
https://doi.org/10.1158/0008-5472.CAN-12-3292
Published: 30 May 2013
View articletitled, PFI-1, a Highly Selective Protein Interaction Inhibitor, Targeting BET Bromodomains
Open the PDF for PFI-1, a Highly Selective Protein Interaction Inhibitor, Targeting BET Bromodomains in another window
Includes: Supplementary data