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Martin Philpott
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Journal Articles

Abstract 3025: PRMT5 inhibition reduces viability and stemness of pediatric high grade glioma

Elizabeth J. Brown, Leire Balaguer-Lluna, Adam Cribbs, Martin Philpott, Ángel M. Carcaboso, Gillian Farnie, Alex N. Bullock
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 3025.
DOI: https://doi.org/10.1158/1538-7445.AM2021-3025
Published: 01 July 2021
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Journal Articles

Inhibition of Histone H3K27 Demethylases Inactivates Brachyury (TBXT) and Promotes Chordoma Cell Death

Lucia Cottone, Adam P. Cribbs, Garima Khandelwal, Graham Wells, Lorena Ligammari, Martin Philpott, Anthony Tumber, Patrick Lombard, Edward S. Hookway, Tamas Szommer, Catrine Johansson, Paul E. Brennan, Nischalan Pillay, Richard G. Jenner, Udo Oppermann, Adrienne M. Flanagan
Journal: Cancer Research
Cancer Res (2020) 80 (20): 4540–4551.
DOI: https://doi.org/10.1158/0008-5472.CAN-20-1387
Published: 15 October 2020
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Includes: Supplementary data
Journal Articles

Generation of a Selective Small Molecule Inhibitor of the CBP/p300 Bromodomain for Leukemia Therapy

Sarah Picaud, Oleg Fedorov, Angeliki Thanasopoulou, Katharina Leonards, Katherine Jones, Julia Meier, Heidi Olzscha, Octovia Monteiro, Sarah Martin, Martin Philpott, Anthony Tumber, Panagis Filippakopoulos, Clarence Yapp, Christopher Wells, Ka Hing Che, Andrew Bannister, Samuel Robson, Umesh Kumar, Nigel Parr, Kevin Lee, Dave Lugo, Philip Jeffrey, Simon Taylor, Matteo L. Vecellio, Chas Bountra, Paul E. Brennan, Alison O'Mahony, Sharlene Velichko, Susanne Müller, Duncan Hay, Danette L. Daniels, Marjeta Urh, Nicholas B. La Thangue, Tony Kouzarides, Rab Prinjha, Jürg Schwaller, Stefan Knapp
Journal: Cancer Research
Series: Author Choice
Cancer Res (2015) 75 (23): 5106–5119.
DOI: https://doi.org/10.1158/0008-5472.CAN-15-0236
Published: 30 November 2015
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Includes: Supplementary data
Journal Articles

PFI-1, a Highly Selective Protein Interaction Inhibitor, Targeting BET Bromodomains

Sarah Picaud, David Da Costa, Angeliki Thanasopoulou, Panagis Filippakopoulos, Paul V. Fish, Martin Philpott, Oleg Fedorov, Paul Brennan, Mark E. Bunnage, Dafydd R. Owen, James E. Bradner, Philippe Taniere, Brendan O'Sullivan, Susanne Müller, Juerg Schwaller, Tatjana Stankovic, Stefan Knapp
Journal: Cancer Research
Series: Author Choice
Cancer Res (2013) 73 (11): 3336–3346.
DOI: https://doi.org/10.1158/0008-5472.CAN-12-3292
Published: 30 May 2013
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Includes: Supplementary data