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Marta M. Alonso
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Journal Articles

Abstract 4659: Depicting ONC201/Delta-24-RGD combination for the treatment of pHGGs and DMGs reveals a therapeutic benefit and a proinflammatory tumor microenvironment remodelation

Daniel de la Nava, Virginia Laspidea, Iker Ausejo-Mauleón, Marc García-Moure, Sabine Mueller, Javad Nazarian, Joshua E. Allen, Oren Becher, Juan Fueyo, Candelaria Gomez-Manzano, Ana Patiño-Garcia, Carl Koschmann, Marta M. Alonso
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 4659.
https://doi.org/10.1158/1538-7445.AM2023-4659
Published: 04 April 2023
View article titled, Abstract 4659: Depicting ONC201/Delta-24-RGD combination for the treatment of pHGGs and DMGs reveals a therapeutic benefit and a proinflammatory tumor microenvironment remodelation
Journal Articles

Abstract 5117: Combined treatment with the epigenetic drug CM272 and an anti-BCL-XL proapoptotic drug sensitizes solid tumors to immune checkpoint blockade

Yaiza Senent, Vicente Fresquet, Victoria Jimenez, Karmele Valencia, Ana Remirez, Francisco Exposito, Marisol Gonzalez-Huarriz, Borja Ruiz-Fernandez de Cordoba, Haritz Moreno, Daniel Ajona, Marta M Alonso, Fernando Lecanda, Antonio Pineda-Lucena, Felipe Prosper, Alfonso Calvo, Jose Angel Martinez-Climent, Ruben Pio
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 5117.
https://doi.org/10.1158/1538-7445.AM2023-5117
Published: 04 April 2023
View article titled, Abstract 5117: Combined treatment with the epigenetic drug CM272 and an anti-BCL-XL proapoptotic drug sensitizes solid tumors to immune checkpoint blockade
Journal Articles

Abstract 6369: Modulation of tumor microenvironment with TIM-3 blockade improves survival in diffuse midline glioma models

Iker Ausejo-Mauleon, Sara Labiano, Virginia Laspidea, Daniel de la Nava, Oren Becher, Mariella G Filbin, Fernando Pastor, Marta M Alonso
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 6369.
https://doi.org/10.1158/1538-7445.AM2023-6369
Published: 04 April 2023
View article titled, Abstract 6369: Modulation of tumor microenvironment with TIM-3 blockade improves survival in diffuse midline glioma models
Journal Articles

Abstract 3263: Implications for cancer viroimmunotherapy: a new adenovirus capsid sensor

Andrew Gregg Gillard, Dong Ho Shin, Virginia Laspidea, Hong Jiang, Fan Xuejun, Yanhua Yi, Marta M. Alonso, Juan Fueyo, Candelaria Gomez-Manzano
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 3263.
https://doi.org/10.1158/1538-7445.AM2023-3263
Published: 04 April 2023
View article titled, Abstract 3263: Implications for cancer viroimmunotherapy: a new adenovirus capsid sensor
Journal Articles

Abstract 3569: Combining oncolytic adenovirus Delta-24-RGDOX with adoptive T cell therapy in localized treatment induces sustainable regression of disseminated solid tumors through antigen spreading

Hong Jiang, Dong Ho Shin, Yanhua Yi, Xuejun Fan, Joy Gumin, Marta M. Alonso, Frederick F. Lang, Candelaria Gomez-Manzano, Juan Fueyo
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 3569.
https://doi.org/10.1158/1538-7445.AM2022-3569
Published: 15 June 2022
View article titled, Abstract 3569: Combining oncolytic adenovirus Delta-24-RGDOX with adoptive T cell therapy in localized treatment induces sustainable regression of disseminated solid tumors through antigen spreading
Journal Articles

Abstract 3565: Viroimmunotherapy for solid tumors results in local and abscopal anti-cancer effects and the remodeling of tumor microenvironment

Arie C. Van Wieren, Sagar Sahoni, Teresa Nguyen, Ashley Ossimetha, Yisel Rivera-Molina, Hong Jiang, Dong Ho Shin, Debora Kim, Xuejun Fan, Yanhua Yi, Natalie M. Melendez-Vazquez, Filipa Godoy-Vitorino, Joy Gumin, Frederick F. Lang, Marta M. Alonso, Juan Fueyo, Candelaria Gomez-Manzano
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 3565.
https://doi.org/10.1158/1538-7445.AM2022-3565
Published: 15 June 2022
View article titled, Abstract 3565: Viroimmunotherapy for solid tumors results in local and abscopal anti-cancer effects and the remodeling of tumor microenvironment
Journal Articles

Abstract 4184: RNA-seq analyses reveal remodeling of tumor microenvironment and reversal of glioma resistance to oncolytic viruses by targeting immunometabolism

Teresa T. Nguyen, Dong Ho Shin, Sagar Sohoni, Sanjay K. Singh, Yisel Rivera-Molina, Hong Jiang, Xuejun Fan, Joy Gumin, Frederick F. Lang, Christopher Alvarez-Breckenridge, Marta M. Alonso, Filipa Godoy-Vitorino, Lijie Zhai, Erik Ladomersky, Kristen L. Lauing, Derek A. Wainwright, Juan Fueyo, Candelaria Gomez-Manzano
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 4184.
https://doi.org/10.1158/1538-7445.AM2022-4184
Published: 15 June 2022
View article titled, Abstract 4184: RNA-seq analyses reveal remodeling of tumor microenvironment and reversal of glioma resistance to oncolytic viruses by targeting immunometabolism
Journal Articles

Abstract 2001: Delta-24-RGDOX oncolytic adenovirus improves the survival by modulating the immune system in DMG models

Virginia Laspidea, Sara Labiano, Sumit Gupta, Hong Jiang, Iker Ausejo-Mauleon, Daniel de la Nava, Marc García-Moure, Javier Marco-Sanz, Reyes Hernández-Osuna, Oren J Becher, Juan Fueyo, Ana Patiño-García, Candelaria Gomez-Manzano, Marta M Alonso
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 2001.
https://doi.org/10.1158/1538-7445.AM2022-2001
Published: 15 June 2022
View article titled, Abstract 2001: Delta-24-RGDOX oncolytic adenovirus improves the survival by modulating the immune system in DMG models
Journal Articles

Abstract 2000: The adenovirus Delta-24-RGD in combination with ONC201 provides a therapeutic benefit and a proinflammatory recruitment in preclinical models of pHGGs and DMGs

Daniel de la Nava, Javier Marco-Sanz, Virginia Laspidea, Sara Labiano, Iker Ausejo-Mauleon, Reyes Hernandez-Osuna, Sabine Mueller, Javad Nazarian, Joshua E. Allen, Oren Becher, Juan Fueyo, Candelaria Gomez-Manzano, Ana Patiño-Garcia, Marta M. Alonso
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 2000.
https://doi.org/10.1158/1538-7445.AM2022-2000
Published: 15 June 2022
View article titled, Abstract 2000: The adenovirus Delta-24-RGD in combination with ONC201 provides a therapeutic benefit and a proinflammatory recruitment in preclinical models of pHGGs and DMGs
Journal Articles

Abstract 3053: Armed oncolytic virus for treatment of pediatric diffuse intrinsic pontine glioma

Sumit Gupta, Virginia Laspidea, Juan Fueyo, Oren Becher, Teresa Nguyen, Dong Ho Shin, Hong Jiang, Sagar Sohoni, Xuejun Fan, Yanhua Yi, Joy Gumin, Frederick Lang, Candelaria Gomez-Manzano, Marta M. Alonso
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 3053.
https://doi.org/10.1158/1538-7445.AM2021-3053
Published: 01 July 2021
View article titled, Abstract 3053: Armed oncolytic virus for treatment of pediatric diffuse intrinsic pontine glioma
Journal Articles

Abstract 3117: Delta-24-RGD/DNX-2401: Oncolytic virotherapy for pediatric high grade glioma and DIPG

Naiara Martinez-Velez, Marc Garcia-Moure, Virginia Laspidea, Maider Varela, Oren Becher, Candelaria Gomez-Manzano, Juan Fueyo, Ana Patiño, Ricardo Diez-Valle, Sonia Tejada-Solis, Marta M. Alonso
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 3117.
https://doi.org/10.1158/1538-7445.AM2019-3117
Published: 01 July 2019
View article titled, Abstract 3117: Delta-24-RGD/DNX-2401: Oncolytic virotherapy for pediatric high grade glioma and DIPG
Journal Articles

Abstract 3192: Aptamers, antibodies and radiotherapy for the treatment of DIPG

Naiara Martinez-Velez, Miguel Marigil, Javier Aristu, Luis Ramos, Fernando Pastor, Ana Patiño-García, Marc García-Moure, Juan Fueyo, Candelaria Gomez-Manzano, Ricardo Diez-Valle, Sonia Tejada, Marta M. Alonso
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 3192.
https://doi.org/10.1158/1538-7445.AM2018-3192
Published: 01 July 2018
View article titled, Abstract 3192: Aptamers, antibodies and radiotherapy for the treatment of DIPG
Journal Articles

Abstract CT027: Oncolytic virus DNX-2401 with a short course of temozolomide for glioblastoma at first recurrence: Clinical data and prognostic biomarkers

Marta M. Alonso, Marc García-Moure, Marisol Gonzalez-Huarriz, Miguel Marigil, Ruben Hernandez-Alcoceba, María Buñales, Sandra Hervás, Jaime Gallego, Candelaria Gomez-Manzano, Juan Fueyo, Frederick Lang, Joanna Peterkin, Ricardo Diez-Valle, Sonia Tejada
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): CT027.
https://doi.org/10.1158/1538-7445.AM2017-CT027
Published: 01 July 2017
View article titled, Abstract CT027: Oncolytic virus DNX-2401 with a short course of temozolomide for glioblastoma at first recurrence: Clinical data and prognostic biomarkers
Journal Articles

Abstract 704: Therapeutic potential of Delta24-ACT, a novel immunostimulatory oncolytic adenovirus, for the treatment of pediatric solid tumors: Initial study in pHGG, DIPG and osteosarcoma

Marc Garcia Moure, Naiara Martínez-Vélez, Enric Xipell, Marisol González-Huarriz, Ana Patiño, Oren J. Becher, Cande Gómez-Manzano, Juan Fueyo, Marta M. Alonso
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 704.
https://doi.org/10.1158/1538-7445.AM2017-704
Published: 01 July 2017
View article titled, Abstract 704: Therapeutic potential of Delta24-ACT, a novel immunostimulatory oncolytic adenovirus, for the treatment of pediatric solid tumors: Initial study in pHGG, DIPG and osteosarcoma
Journal Articles

Abstract 3271: Novel orthotopic pediatric high grade glioma xenografts evaluated with magnetic resonance imaging mimic human disease

Jessica K.R. Boult, Kathryn R. Taylor, Maria Vinci, Sergey Popov, Alexa Jury, Valeria Molinari, Marta M. Alonso, Wendy Ingram, Angel M. Caraboso, Michelle Monje, Suzanne A. Eccles, Chris Jones, Simon P. Robinson
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 3271.
https://doi.org/10.1158/1538-7445.AM2015-3271
Published: 01 August 2015
View article titled, Abstract 3271: Novel orthotopic pediatric high grade glioma xenografts evaluated with magnetic resonance imaging mimic human disease
Journal Articles

Abstract 5402: Enhancing autophagy as a novel approach to target osteosarcoma: combination of Oncolytic adenovirus and chemotherapy

Leire Urquiza, Marta Zalacain, Lucia Marrodan, Maria Dolores Odero, Fernando Lecanda, Candelaria Gomez-Manzano, Juan Fueyo, Luis Sierrasesumaga, Ana Patiño-Garcia, Marta M. Alonso
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 5402.
https://doi.org/10.1158/1538-7445.AM2011-5402
Published: 15 April 2011
View article titled, Abstract 5402: Enhancing autophagy as a novel approach to target osteosarcoma: combination of Oncolytic adenovirus and chemotherapy
Journal Articles

Abstract 3307: The multitasking of Sox2: Maintaining the stemness and inducing the malignant phenotype of gliomas

Marta M. Alonso, Lorea Manterola, Ricardo Diez-Valle, Nahir Cortes-Santiago, Dan Liu, Angel Rubio, Jesus Garcia-Foncillas, Miguel Angel Idoate, Juan Fueyo, Candelaria Gomez-Manzano
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 3307.
https://doi.org/10.1158/1538-7445.AM2011-3307
Published: 15 April 2011
View article titled, Abstract 3307: The multitasking of Sox2: Maintaining the stemness and inducing the malignant phenotype of gliomas
Journal Articles

Abstract 3340: Salinomycin displays more potent anticancer effect against brain tumor stem cells than temozolomide

Marta M. Alonso, Candelaria Gomez-Manzano, Brian Vaillant, Jing Xu, Dan Liu, Hong Jiang, Erin J. White, Howard Colman, Juan Fueyo
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 3340.
https://doi.org/10.1158/1538-7445.AM10-3340
Published: 15 April 2010
View article titled, Abstract 3340: Salinomycin displays more potent anticancer effect against brain tumor stem cells than temozolomide
Journal Articles

Adenovirus-Based Strategies Overcome Temozolomide Resistance by Silencing the O6-Methylguanine-DNA Methyltransferase Promoter

Marta M. Alonso, Candelaria Gomez-Manzano, B. Nebiyou Bekele, W.K. Alfred Yung, Juan Fueyo
Journal: Cancer Research
Cancer Res (2007) 67 (24): 11499–11504.
https://doi.org/10.1158/0008-5472.CAN-07-5312
Published: 18 December 2007
View article titled, Adenovirus-Based Strategies Overcome Temozolomide Resistance by Silencing the O<sup>6</sup>-Methylguanine-DNA Methyltransferase Promoter
Open the PDF for Adenovirus-Based Strategies Overcome Temozolomide Resistance by Silencing the O<sup>6</sup>-Methylguanine-DNA Methyltransferase Promoter in another window
Journal Articles

Cell Cycle–Dependent Nuclear Export of Phosphatase and Tensin Homologue Tumor Suppressor Is Regulated by the Phosphoinositide-3-Kinase Signaling Cascade

Juinn-Lin Liu, Zhenyu Mao, Tiffany A. LaFortune, Marta M. Alonso, Gary E. Gallick, Juan Fueyo, W.K. Alfred Yung
Journal: Cancer Research
Cancer Res (2007) 67 (22): 11054–11063.
https://doi.org/10.1158/0008-5472.CAN-07-1263
Published: 15 November 2007
View article titled, Cell Cycle–Dependent Nuclear Export of Phosphatase and Tensin Homologue Tumor Suppressor Is Regulated by the Phosphoinositide-3-Kinase Signaling Cascade
Open the PDF for Cell Cycle–Dependent Nuclear Export of Phosphatase and Tensin Homologue Tumor Suppressor Is Regulated by the Phosphoinositide-3-Kinase Signaling Cascade in another window