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Journal Articles

Abstract NG14: Dissecting immune microenvironment of T-cell acute lymphoblastic leukemia

Mark Gower, Minerva Fernandez, Andrea Aruda, Mark Minden, Johann Hitzler, Anastasia Tikhonova

Cancer Res (2023) 83 (7_Supplement): NG14.

https://doi.org/10.1158/1538-7445.AM2023-NG14

Published: 04 April 2023

View article titled, Abstract NG14: Dissecting immune microenvironment of T-cell acute lymphoblastic leukemia

Journal Articles

Abstract 3099: The metabolic enzyme hexokinase 2 localizes to the nucleus in AML and normal hematopoietic stem/progenitor cells to maintain stemness

Cancer Res (2021) 81 (13_Supplement): 3099.

https://doi.org/10.1158/1538-7445.AM2021-3099

Published: 01 July 2021

View article titled, Abstract 3099: The metabolic enzyme hexokinase 2 localizes to the nucleus in AML and normal hematopoietic stem/progenitor cells to maintain stemness

Journal Articles

Abstract 4437: Down-modulation of ADAR1-mediated GLI1 editing alters extracellular and immune response genes in multiple myeloma

Leslie A. Crews, Elisa Lazzari, Phoebe K. Mondala, Nathaniel Delos Santos, Amber Miller, Gabriel Pineda, Qingfei Jiang, Anusha-Preethi Ganesan, Christina Wu, Caitlin Costello, Mark Minden, Raffaella Chiaramonte, A. Keith Stewart, Catriona H. M. Jamieson

Cancer Res (2018) 78 (13_Supplement): 4437.

https://doi.org/10.1158/1538-7445.AM2018-4437

Published: 01 July 2018

View article titled, Abstract 4437: Down-modulation of ADAR1-mediated GLI1 editing alters extracellular and immune response genes in multiple myeloma

Journal Articles

Abstract 5173: Genetic profiling of central nervous system dissemination of B-acute lymphoblastic leukemia reveals clonal selection and therapeutic vulnerability

Robert J. Vanner, Stephanie M. Dobson, Ildiko Grandal, Olga Gan, Jessica McLeod, James Kennedy, Veroniqu Voisin, Abdellatif Daghrach, Erwin M. Schoof, Cynthia Guidos, Jayne Danska, Esme Waanders, Mark Minden, Charles G. Mullighan, John E. Dick

Cancer Res (2018) 78 (13_Supplement): 5173.

https://doi.org/10.1158/1538-7445.AM2018-5173

Published: 01 July 2018

View article titled, Abstract 5173: Genetic profiling of central nervous system dissemination of B-acute lymphoblastic leukemia reveals clonal selection and therapeutic vulnerability

Journal Articles

Abstract 3351: Aberrant RNA editing of GLI1 promotes malignant regeneration in multiple myeloma

Elisa Lazzari, Nathaniel Delos Santos, Christina Wu, Heather Leu, Gabriel Pineda, Shawn Ali, Caitlin Costello, Mark Minden, Raffaella Chiaramonte, Leslie Crews, Catriona Jamieson

Cancer Res (2017) 77 (13_Supplement): 3351.

https://doi.org/10.1158/1538-7445.AM2017-3351

Published: 01 July 2017

View article titled, Abstract 3351: Aberrant RNA editing of GLI1 promotes malignant regeneration in multiple myeloma

Journal Articles

Abstract 2414: ADAR1-dependent RNA editing is a mechanism of therapeutic resistance in human plasma cell malignancies

Elisa Lazzari, Leslie A. Crews, Christina Wu, Heather Leu, Shawn Ali, Raffaella Chiaramonte, Mark Minden, Caitlin Costello, Catriona H.M. Jamieson

Cancer Res (2016) 76 (14_Supplement): 2414.

https://doi.org/10.1158/1538-7445.AM2016-2414

Published: 15 July 2016

View article titled, Abstract 2414: ADAR1-dependent RNA editing is a mechanism of therapeutic resistance in human plasma cell malignancies

Journal Articles

Abstract CT147: Phase I studies of AZD1208, a PIM kinase inhibitor, in patients with recurrent or refractory acute myelogenous leukemia or advanced solid tumors

Jorge Cortes, Kenji Tamura, Daniel J. DeAngelo, Johann de Bono, David Lorente, Mark Minden, Geoffrey L. Uy, Hagop Kantarjian, Karen Keating, Kristen McEachern, Karthick Vishwanathan, Robert E. Godin, Janet Elizabeth Pease, Emma Dean

Cancer Res (2016) 76 (14_Supplement): CT147.

https://doi.org/10.1158/1538-7445.AM2016-CT147

Published: 15 July 2016

View article titled, Abstract CT147: Phase I studies of AZD1208, a PIM kinase inhibitor, in patients with recurrent or refractory acute myelogenous leukemia or advanced solid tumors

Journal Articles

Abstract 4260: Clinical testing and implementation of the TruSight Myeloid Next Generation Sequencing (NGS) panel for identification of clinically relevant variants in hematological malignancies

Mariam Thomas, Mahadeo Sukhai, Tong Zhang, Djamel Harbi, Justin De Souza, Katherine MacDonald, Trevor Pugh, Mark Minden, Andre Schuh, Tracy L. Stockley, Suzanne Kamel-Reid

Cancer Res (2015) 75 (15_Supplement): 4260.

https://doi.org/10.1158/1538-7445.AM2015-4260

Published: 01 August 2015

View article titled, Abstract 4260: Clinical testing and implementation of the TruSight Myeloid Next Generation Sequencing (NGS) panel for identification of clinically relevant variants in hematological malignancies

Journal Articles

Targeting Mitochondria with Avocatin B Induces Selective Leukemia Cell Death

Cancer Res (2015) 75 (12): 2478–2488.

https://doi.org/10.1158/0008-5472.CAN-14-2676

Published: 14 June 2015

View article titled, Targeting Mitochondria with Avocatin B Induces Selective Leukemia Cell Death

Includes: Supplementary data

Journal Articles

Abstract 3604: Investigation of the role of CSF-1 and its receptor in the bone marrow stroma microenvironment in acute myeloid leukemia

Ayesha Rashid, Mohammed Fateen, Rhe Juan, Rob C. Laister, Mark Minden

Cancer Res (2014) 74 (19_Supplement): 3604.

https://doi.org/10.1158/1538-7445.AM2014-3604

Published: 01 October 2014

View article titled, Abstract 3604: Investigation of the role of CSF-1 and its receptor in the bone marrow stroma microenvironment in acute myeloid leukemia

Journal Articles

Abstract 247: ADAR1 promotes malignant progenitor reprogramming in chronic myeloid leukemia.

Qingfei Jiang, Leslie A. Crews, Christian L. Barrett, Angela Court-Recart, Daniel Goff, Anil Sadarangani, Jessica Rusert, Sheldon Morris, Lawrence Goldstein, Hye-Jung Chun, Marco Marra, Kelly Fraser, Kim-Hien Dao, Mark Minden, Catriona Jamieson

Cancer Res (2013) 73 (8_Supplement): 247.

https://doi.org/10.1158/1538-7445.AM2013-247

Published: 15 April 2013

View article titled, Abstract 247: ADAR1 promotes malignant progenitor reprogramming in chronic myeloid leukemia.

Journal Articles

Abstract 907: Efficacy of SAR302503, a JAK2 inhibitor, in primary human acute myeloid leukemia xenografts.

Weihsu C. Chen, Andreea C. Popescu, Yan Xing, Gitte Gerhard, Julie Yuan, Mark Minden, Cynthia Guidos, Donna E. Hogge, John E. Dick, Jean CY Wang

Cancer Res (2013) 73 (8_Supplement): 907.

https://doi.org/10.1158/1538-7445.AM2013-907

Published: 15 April 2013

View article titled, Abstract 907: Efficacy of SAR302503, a JAK2 inhibitor, in primary human acute myeloid leukemia xenografts.

Journal Articles

Abstract 2292: Enforced expression of miR-125b promotes the in vivo expansion of human Lin- CB multi-lymphoid progenitors (MLP) and AML leukemia stem cells.

Eric R. Lechman, Karin G. Hermans, Stephanie Dobson, Kolja Eppert, Mark Minden, John E. Dick

Cancer Res (2013) 73 (8_Supplement): 2292.

https://doi.org/10.1158/1538-7445.AM2013-2292

Published: 15 April 2013

View article titled, Abstract 2292: Enforced expression of miR-125b promotes the in vivo expansion of human Lin- CB multi-lymphoid progenitors (MLP) and AML leukemia stem cells.

Journal Articles

Abstract 4123: Investigation of growth factor signaling through macrophage colony stimulating factor (CSF-1) and its receptor (FMS) in the bone marrow stromal microenvironment in acute myeloid leukemia (AML).

Ayesha Rashid, Mohamed Fateen, Aaron Schimmer, Mark Minden

Cancer Res (2013) 73 (8_Supplement): 4123.

https://doi.org/10.1158/1538-7445.AM2013-4123

Published: 15 April 2013

View article titled, Abstract 4123: Investigation of growth factor signaling through macrophage colony stimulating factor (CSF-1) and its receptor (FMS) in the bone marrow stromal microenvironment in acute myeloid leukemia (AML).

Journal Articles

Abstract 1013: Enriched miR-126 bioactivity marks the primitive compartment in human AML and regulates leukemia stem cell numbers

Eric R. Lechman, Bernhard Gentner, Peter van Galen, Kolja Eppert, Katsuto Takenaka, Mark Minden, Luigi Naldini, John E. Dick

Cancer Res (2012) 72 (8_Supplement): 1013.

https://doi.org/10.1158/1538-7445.AM2012-1013

Published: 15 April 2012

View article titled, Abstract 1013: Enriched miR-126 bioactivity marks the primitive compartment in human AML and regulates leukemia stem cell numbers

Journal Articles

Abstract 1123: AML cells have low reserve capacity in their respiratory chain complexes leading to increased sensitivity to palmitate-induced cell death

Shrivani Sriskanthadevan, Marko Skrtic, Bozhena Jhas, Yulia Jitkova, Rose Hurren, Marcela Gronda, Xiaoming Wang, Mahadeo A. Sukhai, Mark Minden, Aaron Schimmer

Cancer Res (2012) 72 (8_Supplement): 1123.

https://doi.org/10.1158/1538-7445.AM2012-1123

Published: 15 April 2012

View article titled, Abstract 1123: AML cells have low reserve capacity in their respiratory chain complexes leading to increased sensitivity to palmitate-induced cell death

Journal Articles

Abstract 1240: Functional deregulation of NF-kB and abnormal TNFa response in acute promyelocytic leukemia

Mariam Thomas, Mahadeo Sukhai, Nicholas Schuh, Yali Xuan, Mark Minden, Suzanne Kamel-Reid

Cancer Res (2010) 70 (8_Supplement): 1240.

https://doi.org/10.1158/1538-7445.AM10-1240

Published: 15 April 2010

View article titled, Abstract 1240: Functional deregulation of NF-kB and abnormal TNFa response in acute promyelocytic leukemia

Journal Articles

Abstract 5010: Nucleophosmin (NPM) is univerally deregulated in acute promyelocytic leukemia

Mahadeo A. Sukhai, Mariam Thomas, Yali Xuan, Shevani Mahindra, Tong Zhang, Patricia Pintor dos Reis, Mark Minden, Suzanne Kamel-Reid

Cancer Res (2010) 70 (8_Supplement): 5010.

https://doi.org/10.1158/1538-7445.AM10-5010

Published: 15 April 2010

View article titled, Abstract 5010: Nucleophosmin (NPM) is univerally deregulated in acute promyelocytic leukemia

Journal Articles

Local Radiotherapy Induces Homing of Hematopoietic Stem Cells to the Irradiated Bone Marrow

Carlo Bastianutto, Asim Mian, Julie Symes, Joseph Mocanu, Nehad Alajez, Gillian Sleep, Wei Shi, Armand Keating, Michael Crump, Mary Gospodarowicz, Jeff Medin, Mark Minden, Fei-Fei Liu

Cancer Res (2007) 67 (21): 10112–10116.

https://doi.org/10.1158/0008-5472.CAN-07-2192

Published: 01 November 2007

View article titled, Local Radiotherapy Induces Homing of Hematopoietic Stem Cells to the Irradiated Bone Marrow

Includes: Supplementary data

Journal Articles

MKC-1 is a novel agent that induces cell cycle arrest and disrupts multiple survival pathways in hematologic cancers

Trisha Denny, Xiaoru Chen, Cassandra Waters, Patricia Burke, Graham Fletcher, Richard Brokx, John Xu, Carolyn Sidor, Mark Minden, Theresa LaVallee, Mark Bray

Cancer Res (2007) 67 (9_Supplement): 5611.

Published: 01 May 2007

View article titled, MKC-1 is a novel agent that induces cell cycle arrest and disrupts multiple survival pathways in hematologic cancers

NARROW

Abstract NG14: Dissecting immune microenvironment of T-cell acute lymphoblastic leukemia

Abstract 3099: The metabolic enzyme hexokinase 2 localizes to the nucleus in AML and normal hematopoietic stem/progenitor cells to maintain stemness

Abstract 4437: Down-modulation of ADAR1-mediated GLI1 editing alters extracellular and immune response genes in multiple myeloma

Abstract 5173: Genetic profiling of central nervous system dissemination of B-acute lymphoblastic leukemia reveals clonal selection and therapeutic vulnerability

Abstract 3351: Aberrant RNA editing of GLI1 promotes malignant regeneration in multiple myeloma

Abstract 2414: ADAR1-dependent RNA editing is a mechanism of therapeutic resistance in human plasma cell malignancies

Abstract CT147: Phase I studies of AZD1208, a PIM kinase inhibitor, in patients with recurrent or refractory acute myelogenous leukemia or advanced solid tumors

Abstract 4260: Clinical testing and implementation of the TruSight Myeloid Next Generation Sequencing (NGS) panel for identification of clinically relevant variants in hematological malignancies

Targeting Mitochondria with Avocatin B Induces Selective Leukemia Cell Death

Abstract 3604: Investigation of the role of CSF-1 and its receptor in the bone marrow stroma microenvironment in acute myeloid leukemia

Abstract 247: ADAR1 promotes malignant progenitor reprogramming in chronic myeloid leukemia.

Abstract 907: Efficacy of SAR302503, a JAK2 inhibitor, in primary human acute myeloid leukemia xenografts.

Abstract 2292: Enforced expression of miR-125b promotes the in vivo expansion of human Lin- CB multi-lymphoid progenitors (MLP) and AML leukemia stem cells.

Abstract 4123: Investigation of growth factor signaling through macrophage colony stimulating factor (CSF-1) and its receptor (FMS) in the bone marrow stromal microenvironment in acute myeloid leukemia (AML).

Abstract 1013: Enriched miR-126 bioactivity marks the primitive compartment in human AML and regulates leukemia stem cell numbers

Abstract 1123: AML cells have low reserve capacity in their respiratory chain complexes leading to increased sensitivity to palmitate-induced cell death

Abstract 1240: Functional deregulation of NF-kB and abnormal TNFa response in acute promyelocytic leukemia

Abstract 5010: Nucleophosmin (NPM) is univerally deregulated in acute promyelocytic leukemia

Local Radiotherapy Induces Homing of Hematopoietic Stem Cells to the Irradiated Bone Marrow

MKC-1 is a novel agent that induces cell cycle arrest and disrupts multiple survival pathways in hematologic cancers

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