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Mark Landers
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Journal Articles

Morphology-Predicted Large-Scale Transition Number in Circulating Tumor Cells Identifies a Chromosomal Instability Biomarker Associated with Poor Outcome in Castration-Resistant Prostate Cancer

Joseph D. Schonhoft, Jimmy L. Zhao, Adam Jendrisak, Emily A. Carbone, Ethan S. Barnett, Melanie A. Hullings, Audrey Gill, Ramsay Sutton, Jerry Lee, Angel E. Dago, Mark Landers, Samuel F. Bakhoum, Yipeng Wang, Mithat Gonen, Ryan Dittamore, Howard I. Scher
Journal: Cancer Research
Cancer Res (2020) 80 (22): 4892–4903.
https://doi.org/10.1158/0008-5472.CAN-20-1216
Published: 13 November 2020
View article titled, Morphology-Predicted Large-Scale Transition Number in Circulating Tumor Cells Identifies a Chromosomal Instability Biomarker Associated with Poor Outcome in Castration-Resistant Prostate Cancer
Open the PDF for Morphology-Predicted Large-Scale Transition Number in Circulating Tumor Cells Identifies a Chromosomal Instability Biomarker Associated with Poor Outcome in Castration-Resistant Prostate Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract 457: HER2, AR protein expression and chromosomal instability in circulating tumor cells (CTCs) of metastatic breast cancer (MBC) patients (pts)

Priscilla Ontiveros, Connie Landaverde, Maren K. Levin, Sarah Hippely, Mark Landers, Yipeng Wang, Ryan Dittamore, Joyce A. O'Shaughnessy
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 457.
https://doi.org/10.1158/1538-7445.AM2019-457
Published: 01 July 2019
View article titled, Abstract 457: HER2, AR protein expression and chromosomal instability in circulating tumor cells (CTCs) of metastatic breast cancer (MBC) patients (pts)
Journal Articles

Abstract 4039: Simultaneous quantification of activated immune cells and PD-L1 expressing circulating tumor cells (CTCs) in peripheral blood of cancer patients receiving checkpoint inhibitor therapy

Rachel Krupa, Robin Richardson, Priscilla Ontiveros, Joseph Schonhoft, Jiyun Byun, David Lu, Sean Nisperos, Yipeng Wang, Mark Landers, Ryan Dittamore
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 4039.
https://doi.org/10.1158/1538-7445.AM2019-4039
Published: 01 July 2019
View article titled, Abstract 4039: Simultaneous quantification of activated immune cells and PD-L1 expressing circulating tumor cells (CTCs) in peripheral blood of cancer patients receiving checkpoint inhibitor therapy
Journal Articles

Abstract 1348: Characterization of SLFN11 protein expression in circulating tumor cells (CTCs) of patients with metastatic castration resistant prostate cancer (mCRPC) prior to platinum based chemotherapy

Luisa Fernandez, John Poirier, Angel Rodriguez, Melanie Hulling, Robin Richardson, Ramsay Sutton, Rhett Jiles, Joseph Schonhoft, Jerry Lee, Nadia Ebrahim, Emily Carbone, Ethan Barnett, Mark Landers, Yipeng Wang, Ryan Dittamore, Charles Rudin, Howard Scher
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 1348.
https://doi.org/10.1158/1538-7445.AM2019-1348
Published: 01 July 2019
View article titled, Abstract 1348: Characterization of SLFN11 protein expression in circulating tumor cells (CTCs) of patients with metastatic castration resistant prostate cancer (mCRPC) prior to platinum based chemotherapy
Journal Articles

Abstract 3885: Evaluation of pharmacokinetics of proxalutamide, a novel androgen receptor antagonist, in treatment for mCRPC patients via CTC enumeration and AR biomarker analysis

Lincy Chu, Phoebe Zhang, Amanda Anderson, Mark Landers, Yipeng Wang, Karl Zhou
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 3885.
https://doi.org/10.1158/1538-7445.AM2019-3885
Published: 01 July 2019
View article titled, Abstract 3885: Evaluation of pharmacokinetics of proxalutamide, a novel androgen receptor antagonist, in treatment for mCRPC patients via CTC enumeration and AR biomarker analysis
Journal Articles

Abstract 2228: Comparison of the Epic CTC HRD assay vs. tumor DDR mutations in metastatic castration-resistant prostate cancer (mCRPC) patients (pts)

Joseph Schonhoft, Adam Jendrisak, Jerry Lee, Angel Rodriguez, Ramsay Sutton, Yipeng Wang, Ryan Dittamore, Mark Landers
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 2228.
https://doi.org/10.1158/1538-7445.AM2019-2228
Published: 01 July 2019
View article titled, Abstract 2228: Comparison of the Epic CTC HRD assay vs. tumor DDR mutations in metastatic castration-resistant prostate cancer (mCRPC) patients (pts)
Journal Articles

Abstract 3616: Low-pass whole-genome sequencing of single circulating tumor cells for detection of tumor mutation burden and chromosomal instability across multiple cancer types

Angel Rodriguez, Jerry Lee, Ramsay Sutton, Rhett Jiles, Gordon Vansant, Yipeng Wang, Mark Landers, Ryan Dittamore
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 3616.
https://doi.org/10.1158/1538-7445.AM2018-3616
Published: 01 July 2018
View article titled, Abstract 3616: Low-pass whole-genome sequencing of single circulating tumor cells for detection of tumor mutation burden and chromosomal instability across multiple cancer types
Journal Articles

Abstract 5536: Simultaneous characterization and quantification of immune cell subpopulations and PD-L1 expressing CTCs in peripheral blood of cancer patients

Rachel Krupa, David Lu, Adam Jendrisak, Angel Rodriguez, Nadia Ebrahim, Robin Richardson, Sean Nisperos, Ryon Graf, Jiyun Byun, Yipeng Wang, Mark Landers, Ryan Dittamore
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 5536.
https://doi.org/10.1158/1538-7445.AM2018-5536
Published: 01 July 2018
View article titled, Abstract 5536: Simultaneous characterization and quantification of immune cell subpopulations and PD-L1 expressing CTCs in peripheral blood of cancer patients
Journal Articles

Abstract 575: Prediction of genomic instability in triple-negative breast cancer patients utilizing a CTC phenotype classifier

Adam Jendrisak, Nadia Ebrahim, Angel Rodriguez, Jerry Lee, Ramsay Sutton, Yipeng Wang, Mark Landers, Ryan Dittamore
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 575.
https://doi.org/10.1158/1538-7445.AM2018-575
Published: 01 July 2018
View article titled, Abstract 575: Prediction of genomic instability in triple-negative breast cancer patients utilizing a CTC phenotype classifier
Journal Articles

Phenotypic Heterogeneity of Circulating Tumor Cells Informs Clinical Decisions between AR Signaling Inhibitors and Taxanes in Metastatic Prostate Cancer

Howard I. Scher, Ryon P. Graf, Nicole A. Schreiber, Brigit McLaughlin, Adam Jendrisak, Yipeng Wang, Jerry Lee, Stephanie Greene, Rachel Krupa, David Lu, Pascal Bamford, Jessica E. Louw, Lyndsey Dugan, Hebert A. Vargas, Martin Fleisher, Mark Landers, Glenn Heller, Ryan Dittamore
Journal: Cancer Research
Series: Author Choice
Cancer Res (2017) 77 (20): 5687–5698.
https://doi.org/10.1158/0008-5472.CAN-17-1353
Published: 15 October 2017
View article titled, Phenotypic Heterogeneity of Circulating Tumor Cells Informs Clinical Decisions between AR Signaling Inhibitors and Taxanes in Metastatic Prostate Cancer
Open the PDF for Phenotypic Heterogeneity of Circulating Tumor Cells Informs Clinical Decisions between AR Signaling Inhibitors and Taxanes in Metastatic Prostate Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract 1740: Phenotypic, genomic, and clinical associations of Circulating Tumor Cells (CTCs) lacking epithelial biomarkers in metastatic Castration Resistant Prostate Cancer (mCRPC)

Ryon P. Graf, Yipeng Wang, Nicole Schreiber, Brigit McLaughlin, Stephanie Greene, Angel Rodriguez, Adam Jendrisak, Jerry Lee, Mark Landers, Ryan Dittamore, Howard I. Scher
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1740.
https://doi.org/10.1158/1538-7445.AM2017-1740
Published: 01 July 2017
View article titled, Abstract 1740: Phenotypic, genomic, and clinical associations of Circulating Tumor Cells (CTCs) lacking epithelial biomarkers in metastatic Castration Resistant Prostate Cancer (mCRPC)
Journal Articles

Abstract 683: Quantification of rare PD-L1 expressing leukocytes and CTCs in peripheral blood of cancer patients

Adam Jendrisak, Jiyun Byun, Mahipal Suraneni, David Lu, Rachel Krupa, Sarah Orr, Ryon Graf, Yipeng Wang, Mark Landers, Ryan Dittamore
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 683.
https://doi.org/10.1158/1538-7445.AM2017-683
Published: 01 July 2017
View article titled, Abstract 683: Quantification of rare PD-L1 expressing leukocytes and CTCs in peripheral blood of cancer patients
Journal Articles

Abstract 1584: Analytical and clinical validation of the Epic Circulating Tumor Cell (CTC) Platform: enrichment-free CTC detection and biomarker characterization

Ryon P. Graf, David T. Valenta, Mark Landers, Bryan Taggart, Stephanie Greene, Shannon L. Werner, Ryan Dittamore, Dena Marrinucci
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 1584.
https://doi.org/10.1158/1538-7445.AM2015-1584
Published: 01 August 2015
View article titled, Abstract 1584: Analytical and clinical validation of the Epic Circulating Tumor Cell (CTC) Platform: enrichment-free CTC detection and biomarker characterization
Journal Articles

Abstract 4843: A next generation sequencing (NGS) genome wide copy number variation (CNV) assay for comparison of circulating tumor cell (CTC) heterogeneity

Stephanie Green, Mark Landers, Jessica Louw, Adam Jendrisak, Ryan Dittamore, Dena Marrinucci
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 4843.
https://doi.org/10.1158/1538-7445.AM2015-4843
Published: 01 August 2015
View article titled, Abstract 4843: A next generation sequencing (NGS) genome wide copy number variation (CNV) assay for comparison of circulating tumor cell (CTC) heterogeneity
Journal Articles

Abstract 1588: Single cell analysis of AR N terminal, AR C terminal and the ARv7 splice variant in the CTCs of metastatic castration resistant prostate cancer (mCRPC) patients

James Kelvin, David Lu, Davin Packer, Richard Bambury, Dana Rathkopf, Nicole Schreiber, Zaina Arslan, Natalie Prigozhina, David Brown, Rachel Krupa, Edward Swangren, Mark Landers, Florence Lee, Dena Marrinucci, Ryan Dittamore, Howard I. Scher
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 1588.
https://doi.org/10.1158/1538-7445.AM2015-1588
Published: 01 August 2015
View article titled, Abstract 1588: Single cell analysis of AR N terminal, AR C terminal and the ARv7 splice variant in the CTCs of metastatic castration resistant prostate cancer (mCRPC) patients
Journal Articles

Abstract 1586: Recovery and characterization of circulating tumor cells (CTCs) in cryopreserved metastatic castrate-resistant prostate cancer (mCRPC) patient samples

David Lu, Melissa Harvey, Ravi Madan, Christopher Heery, Jennifer Marte, Sharon Beasley, Mark Landers, Rachel Krupa, Jessica Louw, Justin Wahl, Natalee Bales, Dena Marrinucci, Jeffrey Schlom, James Gulley, Ryan Dittamore
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 1586.
https://doi.org/10.1158/1538-7445.AM2015-1586
Published: 01 August 2015
View article titled, Abstract 1586: Recovery and characterization of circulating tumor cells (CTCs) in cryopreserved metastatic castrate-resistant prostate cancer (mCRPC) patient samples
Journal Articles

Abstract 4143: Targeted RNA sequencing for expression analysis of breast cancer patient samples using a biomarker gene panel.

Kahuku Oades, Lien Vo, Jerry Lee, Mark Landers, Yipeng Wang, Byung-In Lee, Joseph Monforte
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 4143.
https://doi.org/10.1158/1538-7445.AM2013-4143
Published: 15 April 2013
View article titled, Abstract 4143: Targeted RNA sequencing for expression analysis of breast cancer patient samples using a biomarker gene panel.
Journal Articles

Abstract #1394: MicroRNA expression profiles predict HER-2/neu oncoprotein and EGF receptor status of human breast cancer

James Wittliff, D. Alan Kerr, Mason Brooks, Daniel Krissinger, Mark Landers, Christopher Adams
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 1394.
Published: 01 May 2009
View article titled, Abstract #1394: MicroRNA expression profiles predict HER-2/neu oncoprotein and EGF receptor status of human breast cancer
Journal Articles

NCodeTM miRNA analysis platform identifies differentially expressed novel microRNAs in adenocarcinoma using clinical human tissue samples provided by BioServe.

Mason Brooks, Daniel Krissinger, Mark Landers, Kristin Wiederholt, Christopher Adams, Mike Seddon, Vipin Adhlahka
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): LB-287.
Published: 01 May 2008
View article titled, NCode<sup>TM</sup> miRNA analysis platform identifies differentially expressed novel microRNAs in adenocarcinoma using clinical human tissue samples provided by BioServe.
Journal Articles

Validating microRNA targeting of downregulated breast cancer biomarkers

Lisa Wenrich, Mark Landers, Xiquan Liang, Brad Love, Marshall Pope, Christopher Adams
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): LB-50.
Published: 01 May 2007
View article titled, Validating microRNA targeting of downregulated breast cancer biomarkers