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Journal Articles

Sensitization to the Lysosomal Cell Death Pathway by Oncogene-Induced Down-regulation of Lysosome-Associated Membrane Proteins 1 and 2

Nicole Fehrenbacher, Lone Bastholm, Thomas Kirkegaard-Sørensen, Bo Rafn, Trine Bøttzauw, Christina Nielsen, Ekkehard Weber, Senji Shirasawa, Tuula Kallunki, Marja Jäättelä

Cancer Res (2008) 68 (16): 6623–6633.

https://doi.org/10.1158/0008-5472.CAN-08-0463

Published: 12 August 2008

View article titled, Sensitization to the Lysosomal Cell Death Pathway by Oncogene-Induced Down-regulation of Lysosome-Associated Membrane Proteins 1 and 2

Includes: Supplementary data

Journal Articles

Lens Epithelium-Derived Growth Factor Is an Hsp70-2 Regulated Guardian of Lysosomal Stability in Human Cancer

Mads Daugaard, Thomas Kirkegaard-Sørensen, Marie Stampe Ostenfeld, Mads Aaboe, Maria Høyer-Hansen, Torben Falck Ørntoft, Mikkel Rohde, Marja Jäättelä

Cancer Res (2007) 67 (6): 2559–2567.

https://doi.org/10.1158/0008-5472.CAN-06-4121

Published: 15 March 2007

View article titled, Lens Epithelium-Derived Growth Factor Is an Hsp70-2 Regulated Guardian of Lysosomal Stability in Human Cancer

Journal Articles

Vincristine Induces Dramatic Lysosomal Changes and Sensitizes Cancer Cells to Lysosome-Destabilizing Siramesine

Line Groth-Pedersen, Marie Stampe Ostenfeld, Maria Høyer-Hansen, Jesper Nylandsted, Marja Jäättelä

Cancer Res (2007) 67 (5): 2217–2225.

https://doi.org/10.1158/0008-5472.CAN-06-3520

Published: 01 March 2007

View article titled, Vincristine Induces Dramatic Lysosomal Changes and Sensitizes Cancer Cells to Lysosome-Destabilizing Siramesine

Journal Articles

c-Jun NH₂-Terminal Kinase 2 Is Required for Ras Transformation Independently of Activator Protein 1

Christina Nielsen, Jacob Thastrup, Trine Bøttzauw, Marja Jäättelä, Tuula Kallunki

Cancer Res (2007) 67 (1): 178–185.

https://doi.org/10.1158/0008-5472.CAN-06-2801

Published: 08 January 2007

View article titled, c-Jun NH<sub>2</sub>-Terminal Kinase 2 Is Required for Ras Transformation Independently of Activator Protein 1

Journal Articles

Effective Tumor Cell Death by σ-2 Receptor Ligand Siramesine Involves Lysosomal Leakage and Oxidative Stress

Marie Stampe Ostenfeld, Nicole Fehrenbacher, Maria Høyer-Hansen, Christian Thomsen, Thomas Farkas, Marja Jäättelä

Cancer Res (2005) 65 (19): 8975–8983.

https://doi.org/10.1158/0008-5472.CAN-05-0269

Published: 03 October 2005

View article titled, Effective Tumor Cell Death by σ-2 Receptor Ligand Siramesine Involves Lysosomal Leakage and Oxidative Stress

Journal Articles

Lysosomes as Targets for Cancer Therapy

Nicole Fehrenbacher, Marja Jäättelä

Cancer Res (2005) 65 (8): 2993–2995.

https://doi.org/10.1158/0008-5472.CAN-05-0476

Published: 15 April 2005

View article titled, Lysosomes as Targets for Cancer Therapy

Journal Articles

Sensitization to the Lysosomal Cell Death Pathway upon Immortalization and Transformation

Nicole Fehrenbacher, Mads Gyrd-Hansen, Birgit Poulsen, Ute Felbor, Tuula Kallunki, Marianne Boes, Ekkehard Weber, Marcel Leist, Marja Jäättelä

Cancer Res (2004) 64 (15): 5301–5310.

https://doi.org/10.1158/0008-5472.CAN-04-1427

Published: 02 August 2004

View article titled, Sensitization to the Lysosomal Cell Death Pathway upon Immortalization and Transformation

Journal Articles

Chemosensitization by a Non-apoptogenic Heat Shock Protein 70-Binding Apoptosis-Inducing Factor Mutant

Elise Schmitt, Arnaud Parcellier, Sandeep Gurbuxani, Celine Cande, Arlette Hammann, Maria Celia Morales, Clayton R. Hunt, David J. Dix, Romano T. Kroemer, Fabrizio Giordanetto, Marja Jäättelä, Josef M. Penninger, Alena Pance, Guido Kroemer, Carmen Garrido

Cancer Res (2003) 63 (23): 8233–8240.

Published: 16 December 2003

View article titled, Chemosensitization by a Non-apoptogenic Heat Shock Protein 70-Binding Apoptosis-Inducing Factor Mutant

Journal Articles

Eradication of Glioblastoma, and Breast and Colon Carcinoma Xenografts by Hsp70 Depletion

Jesper Nylandsted, Wolfgang Wick, Ulrich A. Hirt, Karsten Brand, Mikkel Rohde, Marcel Leist, Michael Weller, Marja Jäättelä

Cancer Res (2002) 62 (24): 7139–7142.

Published: 15 December 2002

View article titled, Eradication of Glioblastoma, and Breast and Colon Carcinoma Xenografts by Hsp70 Depletion

Journal Articles

Vascular Endothelial Growth Factor C Promotes Tumor Lymphangiogenesis and Intralymphatic Tumor Growth

Terhi Karpanen, Mikala Egeblad, Marika J. Karkkainen, Hajime Kubo, Seppo Ylä-Herttuala, Marja Jäättelä, Kari Alitalo

Cancer Res (2001) 61 (5): 1786–1790.

Published: 01 March 2001

View article titled, Vascular Endothelial Growth Factor C Promotes Tumor Lymphangiogenesis and Intralymphatic Tumor Growth

Journal Articles

Apoptosis Induced by Vitamin D Compounds in Breast Cancer Cells Is Inhibited by Bcl-2 but Does Not Involve Known Caspases or p53

Ida Stenfeldt Mathiasen, Ulrikm Lademann, Marja Jäättelä

Cancer Res (1999) 59 (19): 4848–4856.

Published: 01 October 1999

View article titled, Apoptosis Induced by Vitamin D Compounds in Breast Cancer Cells Is Inhibited by Bcl-2 but Does Not Involve Known Caspases or p53

NARROW

Sensitization to the Lysosomal Cell Death Pathway by Oncogene-Induced Down-regulation of Lysosome-Associated Membrane Proteins 1 and 2

Lens Epithelium-Derived Growth Factor Is an Hsp70-2 Regulated Guardian of Lysosomal Stability in Human Cancer

Vincristine Induces Dramatic Lysosomal Changes and Sensitizes Cancer Cells to Lysosome-Destabilizing Siramesine

c-Jun NH₂-Terminal Kinase 2 Is Required for Ras Transformation Independently of Activator Protein 1

Effective Tumor Cell Death by σ-2 Receptor Ligand Siramesine Involves Lysosomal Leakage and Oxidative Stress

Lysosomes as Targets for Cancer Therapy

Sensitization to the Lysosomal Cell Death Pathway upon Immortalization and Transformation

Chemosensitization by a Non-apoptogenic Heat Shock Protein 70-Binding Apoptosis-Inducing Factor Mutant

Eradication of Glioblastoma, and Breast and Colon Carcinoma Xenografts by Hsp70 Depletion

Vascular Endothelial Growth Factor C Promotes Tumor Lymphangiogenesis and Intralymphatic Tumor Growth

Apoptosis Induced by Vitamin D Compounds in Breast Cancer Cells Is Inhibited by Bcl-2 but Does Not Involve Known Caspases or p53

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