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Journal Articles

Abstract 1284: The tumor scaffold protein SQSTM1 at the crossroads of DNA damage and immunotherapy responses in solid tumors

Free
Iris Grosjean, Grégoire D’Andréa, Nathalie Yazbeck, Amine Belaid, Barnabé Roméo, Marie Angela Domdom, Nicolas Guillot, Eric Gilson, Emmanuel Chamorey, Gérard Milano, Véronique Hofman, Marius Ilié, Isabelle Benard-Thiery, Simon Heeke, Patrick Brest, François Ghiringhelli, Paul Hofman, Baharia Mograbi
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 1284.
https://doi.org/10.1158/1538-7445.AM2022-1284
Published: 15 June 2022
View articletitled, Abstract 1284: The tumor scaffold protein SQSTM1 at the crossroads of DNA damage and immunotherapy responses in solid tumors
Journal Articles

Abstract 1265: Identification of a predictive circulating immunological signature of response to immune checkpoint inhibitors in non-small cell lung cancer

Free
Wassila Khatir, Olivier Humbert, Jaap Neels, Léa Berland, Jonathan Benzaquen, Fabian Andrés Gallardo Rivera, Maryline Allegra, Myriam Salah, Virginie Tanga, Olivier Bordone, Julien Fayada, Virginie Lespinet-Fabre, Elodie Long-Mira, Sandra Lassalle, Patrick Brest, Valérie Vouret, Charlotte Maniel, Jacques Boutros, Simon Heeke, Véronique Hofman, Charles-Hugo Marquette, Paul Hofman, Marius Ilie
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 1265.
https://doi.org/10.1158/1538-7445.AM2022-1265
Published: 15 June 2022
View articletitled, Abstract 1265: Identification of a predictive circulating immunological signature of response to immune checkpoint inhibitors in non-small cell lung cancer
Journal Articles

Abstract 461: Mixed supervision to improve the classification and localization: Coherence of tumors in histological slides

Free
Paul Tourniaire, Marius Ilie, Paul Hofman, Nicholas Ayache, Hervé Delingette
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 461.
https://doi.org/10.1158/1538-7445.AM2022-461
Published: 15 June 2022
View articletitled, Abstract 461: Mixed supervision to improve the classification and localization: Coherence of tumors in histological slides
Journal Articles

Abstract 5299: Detection of ALK fusion transcripts in plasma of non-small cell lung cancer patients using a novel RT-PCR based assay

Free
Simon Heeke, Marius Ilié, Maryline Allegra, Audrey Vallée, Carole Salacroup, Virginie Tanga, Véronique Hofman, Jaya Rajamani, Michael Lee, Ellen Ordinario, Marc G. Denis, Paul Hofman
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 5299.
https://doi.org/10.1158/1538-7445.AM2020-5299
Published: 15 August 2020
View articletitled, Abstract 5299: Detection of ALK fusion transcripts in plasma of non-small cell lung cancer patients using a novel RT-PCR based assay
Journal Articles

Abstract 4889: Comparison of tumor mutational burden using the Ion Oncomine™ TML and FoundationOne™ assays with routine clinical FFPE tissue samples to predict durable clinical benefit in lung cancer and melanoma patients - a multivariate analysis integrating PD-L1 and CD8+ evaluation

Free
Simon Heeke, Jonathan Benzaquen, Elodie Long-Mira, Benoit Audelan, Virginie Lespinet, Olivier Bordone, Salomé Lalvé, Katia Zahaf, Michel Poudenx, Pierre-Michel Dugourd, Madleen Chassang, Thierry Passeron, Hervé Delingette, Charles-Hugo Marquette, Véronique Hofman, Marius Ilié, Paul Hofman
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 4889.
https://doi.org/10.1158/1538-7445.AM2019-4889
Published: 01 July 2019
View articletitled, Abstract 4889: Comparison of tumor mutational burden using the Ion Oncomine™ TML and FoundationOne™ assays with routine clinical FFPE tissue samples to predict durable clinical benefit in lung cancer and melanoma patients - a multivariate analysis integrating PD-L1 and CD8+ evaluation
Journal Articles

Abstract 3127: Multicenter study evaluating the ROS1 status in lung adenocarcinoma using the novel SP384 immunohistochemistry clone. Towards a new algorithm for ROS1 status assessment in routine

Free
Véronique Hofman, Isabelle Rouquette, Sandra Lassalle, Simon Heeke, Jean-Christophe Sabourin, Nicolas Piton, Julien Mazières, Jean-Michel Vignaud, Clémence Yguel, Anne Laure Lepage, Frédéric Bibeau, Elodie Long-Mira, Katia Zahaf, Hugues Begueret, Jonathan Benzaquen, Michel Poudenx, Charles-Hugo Marquette, Marius Ilie, Paul Hofman
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 3127.
https://doi.org/10.1158/1538-7445.AM2019-3127
Published: 01 July 2019
View articletitled, Abstract 3127: Multicenter study evaluating the ROS1 status in lung adenocarcinoma using the novel SP384 immunohistochemistry clone. Towards a new algorithm for ROS1 status assessment in routine
Journal Articles

Matrix Stiffening and EGFR Cooperate to Promote the Collective Invasion of Cancer Cells

Free
Eloise M. Grasset, Thomas Bertero, Alexandre Bozec, Jonas Friard, Isabelle Bourget, Sabrina Pisano, Margaux Lecacheur, Majdi Maiel, Caroline Bailleux, Alexander Emelyanov, Marius Ilie, Paul Hofman, Guerrino Meneguzzi, Christophe Duranton, Dmitry V. Bulavin, Cedric Gaggioli
Journal: Cancer Research
Cancer Res (2018) 78 (18): 5229–5242.
https://doi.org/10.1158/0008-5472.CAN-18-0601
Published: 14 September 2018
View articletitled, Matrix Stiffening and EGFR Cooperate to Promote the Collective Invasion of Cancer Cells
Open the PDF for Matrix Stiffening and EGFR Cooperate to Promote the Collective Invasion of Cancer Cells in another window
Includes: Supplementary data
Journal Articles

Abstract 5529: PD-L1 and CD8 IHC dual assessment in NSCLC using the Halioseek® assay: A multicentric study

Free
Luciana Batista, Nicolas Brandone, Stéphane Garcia, Yanis Boumber, Essel Dulaimi, Philippe Tanière, Paul Hofman, Marius Ilié, Julien Adam, Jérôme Galon, Catherine Gerbon, Jacques Fieschi
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 5529.
https://doi.org/10.1158/1538-7445.AM2018-5529
Published: 01 July 2018
View articletitled, Abstract 5529: PD-L1 and CD8 IHC dual assessment in NSCLC using the Halioseek® assay: A multicentric study
Journal Articles

Abstract 3044: Rapid decay of engulfed extracellular miRNA by XRN1 exonuclease promotes transient epithelial-mesenchymal transition

Free
Joséphine Zangari, Marius Ilie, Florian Rouaud, Laurie Signetti, Mickaël Ohanna, Robin Didier, Barnabé Roméo, Dana Goldoni, Nicolas Nottet, Cathy Staedel, Jocelyn Gal, Bernard Mari, Baharia Mograbi, Paul Hofman, Patrick Brest
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 3044.
https://doi.org/10.1158/1538-7445.AM2017-3044
Published: 01 July 2017
View articletitled, Abstract 3044: Rapid decay of engulfed extracellular miRNA by XRN1 exonuclease promotes transient epithelial-mesenchymal transition
Journal Articles

Abstract 867: Circulating lung tumor cells capture extracellular vesicles conferring resistance phenotype by the occurrence of epithelial-mesenchymal transition reprogramming

Free
Josephine Zangari, Marius Ilie, Simon Heeke, Véronique Hofman, Baharia Mograbi, Sophie Raynaud, Salome Lalvee, Nathalie Yazbeck, Charles-Hugo Marquette, Sylvie Leroy, Patrick Brest, Paul Hofman
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 867.
https://doi.org/10.1158/1538-7445.AM2017-867
Published: 01 July 2017
View articletitled, Abstract 867: Circulating lung tumor cells capture extracellular vesicles conferring resistance phenotype by the occurrence of epithelial-mesenchymal transition reprogramming
Journal Articles

Abstract 2218: Distribution and prognostic relevance of PD-1/PD-L1 immune checkpoints and tumor-infiltrating lymphocytes in early-stage pulmonary basaloid squamous cell carcinoma

Free
Marius Ilie, Catherine Butori, Véronique Hofman, Christelle Bonnetaud, Sandra Lassalle, Elodie Long, Salomé Lalvée, Nicolas Vénissac, Jérôme Mouroux, Charles Hugo Marquette, Paul Hofman
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 2218.
https://doi.org/10.1158/1538-7445.AM2016-2218
Published: 15 July 2016
View articletitled, Abstract 2218: Distribution and prognostic relevance of PD-1/PD-L1 immune checkpoints and tumor-infiltrating lymphocytes in early-stage pulmonary basaloid squamous cell carcinoma
Journal Articles

Abstract 3230: The role of TRF2 on tumor progression in non-small cell lung cancer: potential modulating effect on myeloid cells

Free
Linda Bouhlel, Marius Ilie, Laurie Signetti, Julien Cherfils-Vicini, Eric Selva, Patrick Brest, Charles Hugo Marquette, Eric Gilson, Paul Hofman
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 3230.
https://doi.org/10.1158/1538-7445.AM2016-3230
Published: 15 July 2016
View articletitled, Abstract 3230: The role of TRF2 on tumor progression in non-small cell lung cancer: potential modulating effect on myeloid cells
Journal Articles

Abstract 2220: PD-L1 expression in primary tumor and circulating tumor cells in patients with small cell lung carcinomas

Free
Marius Ilie, Véronique Hofman, Elodie Long, Catherine Butori, Salomé Lalvée, Eric Selva, Nicolas Vénissac, Jérôme Mouroux, Charles Hugo Marquette, Paul Hofman
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 2220.
https://doi.org/10.1158/1538-7445.AM2016-2220
Published: 15 July 2016
View articletitled, Abstract 2220: PD-L1 expression in primary tumor and circulating tumor cells in patients with small cell lung carcinomas
Journal Articles

Abstract 4025: Impact of Kras mutant subtypes on PD-L1 expression in lung adenocarcinoma

Free
Marius Ilie, Laetitia Fazzalari, Nicolas Guibert, Nathalie Yazbeck, Laurie Signetti, Véronique Hofman, Elodie Long, Katia Zahaf, Julien Fayada, Virginie Lespinet, Olivier Bordone, Virginie Tanga, Kevin Washetine, Nicolas Vénissac, Jérôme Mouroux, Charles Hugo Marquette, Patrick Brest, Paul Hofman
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 4025.
https://doi.org/10.1158/1538-7445.AM2016-4025
Published: 15 July 2016
View articletitled, Abstract 4025: Impact of Kras mutant subtypes on PD-L1 expression in lung adenocarcinoma
Journal Articles

Abstract 1580: MET expression in circulating tumor cells (CTCs) isolated on the ISET platform correlates with MET expression in matched tumor tissue in advanced NSCLC patients

Free
Marius Ilie, Edith Szafer-Glusman, Veronique Hofman, Rebecca Suttman, Walter Darbonne, Charles-Hugo Marquette, David S. Shames, Elizabeth Punnoose, Paul Hofman
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 1580.
https://doi.org/10.1158/1538-7445.AM2015-1580
Published: 01 August 2015
View articletitled, Abstract 1580: MET expression in circulating tumor cells (CTCs) isolated on the ISET platform correlates with MET expression in matched tumor tissue in advanced NSCLC patients
Journal Articles

Genetic and Pharmacological Inactivation of the Purinergic P2RX7 Receptor Dampens Inflammation but Increases Tumor Incidence in a Mouse Model of Colitis-Associated Cancer

Free
Paul Hofman, Julien Cherfils-Vicini, Marie Bazin, Marius Ilie, Thierry Juhel, Xavier Hébuterne, Eric Gilson, Annie Schmid-Alliana, Olivier Boyer, Sahil Adriouch, Valérie Vouret-Craviari
Journal: Cancer Research
Cancer Res (2015) 75 (5): 835–845.
https://doi.org/10.1158/0008-5472.CAN-14-1778
Published: 01 March 2015
View articletitled, Genetic and Pharmacological Inactivation of the Purinergic P2RX7 Receptor Dampens Inflammation but Increases Tumor Incidence in a Mouse Model of Colitis-Associated Cancer
Open the PDF for Genetic and Pharmacological Inactivation of the Purinergic P2RX7 Receptor Dampens Inflammation but Increases Tumor Incidence in a Mouse Model of Colitis-Associated Cancer in another window
Includes: Supplementary data
Journal Articles

Autophagy Plays a Critical Role in the Degradation of Active RHOA, the Control of Cell Cytokinesis, and Genomic Stability

Free
Amine Belaid, Michaël Cerezo, Abderrahman Chargui, Elisabeth Corcelle–Termeau, Florence Pedeutour, Sandy Giuliano, Marius Ilie, Isabelle Rubera, Michel Tauc, Sophie Barale, Corinne Bertolotto, Patrick Brest, Valérie Vouret-Craviari, Daniel J. Klionsky, Georges F. Carle, Paul Hofman, Baharia Mograbi
Journal: Cancer Research
Cancer Res (2013) 73 (14): 4311–4322.
https://doi.org/10.1158/0008-5472.CAN-12-4142
Published: 15 July 2013
View articletitled, Autophagy Plays a Critical Role in the Degradation of Active RHOA, the Control of Cell Cytokinesis, and Genomic Stability
Open the PDF for Autophagy Plays a Critical Role in the Degradation of Active RHOA, the Control of Cell Cytokinesis, and Genomic Stability in another window
Includes: Multimedia, Supplementary data
Journal Articles

Expression of a Truncated Active Form of VDAC1 in Lung Cancer Associates with Hypoxic Cell Survival and Correlates with Progression to Chemotherapy Resistance

Free
M. Christiane Brahimi-Horn, Danya Ben-Hail, Marius Ilie, Pierre Gounon, Matthieu Rouleau, Véronique Hofman, Jérôme Doyen, Bernard Mari, Varda Shoshan-Barmatz, Paul Hofman, Jacques Pouysségur, Nathalie M. Mazure
Journal: Cancer Research
Cancer Res (2012) 72 (8): 2140–2150.
https://doi.org/10.1158/0008-5472.CAN-11-3940
Published: 16 April 2012
View articletitled, Expression of a Truncated Active Form of VDAC1 in Lung Cancer Associates with Hypoxic Cell Survival and Correlates with Progression to Chemotherapy Resistance
Open the PDF for Expression of a Truncated Active Form of VDAC1 in Lung Cancer Associates with Hypoxic Cell Survival and Correlates with Progression to Chemotherapy Resistance in another window
Includes: Supplementary data