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Marios Giannakis
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Journal Articles

Abstract 684: Body mass index throughout adulthood and incidence of colorectal cancer subclassified by T cell, macrophage, and myeloid cell infiltrates in cancer tissue

Tomotaka Ugai, Juha P. Väyrynen, Yasutoshi Takashima, Seyed Mostafa Mousavi Kahaki, Benjamin Langworthy, Koichiro Haruki, Naohiko Akimoto, Mai Chan Lau, Rong Zhong, Sara A. Väyrynen, Melissa Zhao, Andressa Dias Costa, Jennifer Borowsky, Jennifer L. Guerriero, Xuehong Zhang, Andrew T. Chan, Molin Wang, Marios Giannakis, Jeffrey A. Meyerhardt, Edward L. Giovannucci, Jonathan A. Nowak, Shuji Ogino
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 684.
DOI: https://doi.org/10.1158/1538-7445.AM2022-684
Published: 15 June 2022
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Journal Articles

Abstract CT129: ARC-3: Updated results of etrumadenant (AB928) + modified FOLFOX-6 (mFOLFOX-6) in metastatic colorectal cancer (mCRC) patients

Michael Cecchini, Cheng Quah, Shiyao Liu, Rachel Woloski, Akshata Udyavar, Marios Giannakis
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): CT129.
DOI: https://doi.org/10.1158/1538-7445.AM2021-CT129
Published: 01 July 2021
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Journal Articles

Abstract LB090: Associations of somatically mutated genes and pathways with colorectal cancer specific survival in 4,500 colorectal cancer patients

Tabitha A. Harrison, Syed H. Zaidi, Conghui Qu, Amanda I. Phipps, Robert S. Steinfelder, Quang M. Trinh, Sonja I. Berndt, Daniel D. Buchanan, Peter T. Campbell, Andrew T. Chan, Kim F. Doheny, David A. Drew, Jane C. Figueiredo, Steven J. Gallinger, Marios Giannakis, Andrea Gsur, Marc J. Gunter, Michael Hoffmeister, Wen-Yi Huang, Paul J. Limburg, Victor Moreno, Polly A. Newcomb, Shuji Ogino, Ross L. Prentice, Tameka Shelford, Wei Sun, Stephen N. Thibodeau, Li Hsu, Ulrike Peters
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): LB090.
DOI: https://doi.org/10.1158/1538-7445.AM2021-LB090
Published: 01 July 2021
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Journal Articles

Abstract 960: RNF43 G659fs is an oncogenic mutation in colorectal cancer and sensitizes tumor cells to PI3K/mTOR inhibition

Lishan Fang, Dane Ford-Roshon, Max Russo, Casey O'Brien, Carino Gurjao, Maximilien Grandclaudon, Steven M. Corsello, Srivatsan Raghavan, Namrata Udeshi, James Berstler, Ewa Sicinska, Kimmie Ng, Marios Giannakis
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 960.
DOI: https://doi.org/10.1158/1538-7445.AM2021-960
Published: 01 July 2021
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Journal Articles

Abstract 2733: Smoking and colorectal cancer Iincidence by tumor microenvironment in cancer tissue

Tomotaka Ugai, Juha P. Väyrynen, Koichiro Haruki, Naohiko Akimoto, Mai Chan Lau, Rong Zhong, Sara A. Väyrynen, Melissa Zhao, Andressa Dias Costa, Jennifer Borowsky, Jennifer L. Guerriero, Charles S. Fuchs, Xuehong Zhang, Molin Wang, Marios Giannakis, Jeffrey A. Meyerhardt, Jonathan A. Nowak, Shuji Ogino
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2733.
DOI: https://doi.org/10.1158/1538-7445.AM2021-2733
Published: 01 July 2021
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Journal Articles

Intake of Dietary Fruit, Vegetables, and Fiber and Risk of Colorectal Cancer According to Molecular Subtypes: A Pooled Analysis of 9 Studies

Akihisa Hidaka, Tabitha A. Harrison, Yin Cao, Lori C. Sakoda, Richard Barfield, Marios Giannakis, Mingyang Song, Amanda I. Phipps, Jane C. Figueiredo, Syed H. Zaidi, Amanda E. Toland, Efrat L. Amitay, Sonja I. Berndt, Ivan Borozan, Andrew T. Chan, Steven Gallinger, Marc J. Gunter, Mark A. Guinter, Sophia Harlid, Heather Hampel, Mark A. Jenkins, Yi Lin, Victor Moreno, Polly A. Newcomb, Reiko Nishihara, Shuji Ogino, Mireia Obón-Santacana, Patrick S. Parfrey, John D. Potter, Martha L. Slattery, Robert S. Steinfelder, Caroline Y. Um, Xiaoliang Wang, Michael O. Woods, Bethany Van Guelpen, Stephen N. Thibodeau, Michael Hoffmeister, Wei Sun, Li Hsu, Daniel D. Buchanan, Peter T. Campbell, Ulrike Peters
Journal: Cancer Research
Cancer Res (2020) 80 (20): 4578–4590.
DOI: https://doi.org/10.1158/0008-5472.CAN-20-0168
Published: 15 October 2020
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Includes: Supplementary data
Journal Articles

Abstract CT034: Phase I study of WNT974 + spartalizumab in patients (pts) with advanced solid tumors

Filip Janku, Filip de Vos, Maria de Miguel, Patrick Forde, Antoni Ribas, Misako Nagasaka, Guillem Argiles, Ana Maria Arance, Aitano Calvo, Marios Giannakis, Maritza Melendez, Jiachang Gong, Sebastian Szpakowski, Rebecca Kan, Susan E. Moody, Maja De Jonge
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): CT034.
DOI: https://doi.org/10.1158/1538-7445.AM2020-CT034
Published: 15 August 2020
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Journal Articles

Abstract NG13: Metabolomic adaptations and correlates of survival to immune checkpoint blockade

Haoxin Li, Kevin Bullock, Carino Gurjao, David Braun, Sachet A. Shukla, Dominick Bosse, Aly-Khan A. Lalani, Shuba Gopal, Chelsea Jin, Christine Horak, Megan Wind-Rotolo, Sabina Signoretti, David F. McDermott, Gordon J. Freeman, Eliezer M. Van Allen, Stuart L. Schreiber, Frank Stephen Hodi, William R. Sellers, Levi A. Garraway, Clary B. Clish, Toni K. Choueiri, Marios Giannakis
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): NG13.
DOI: https://doi.org/10.1158/1538-7445.AM2020-NG13
Published: 15 August 2020
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Journal Articles

Abstract 1598: Deep targeted sequencing of colorectal cancer cases to study associations of molecular subtypes with clinical, genetic, and lifestyle risk factors

Syed H. Zaidi, Amanda I. Phipps, Tabitha A. Harrison, Robert S. Steinfelder, Quang Trinh, Barbara L. Banbury, Adilya Rafikova, Megan Van Tassel, Emma Reid, Stefanie Brezina, Marios Giannakis, Charles S. Fuchs, Li Hsu, Andrea Gsur, Shuji Ogino, Steven Gallinger, Polly A. Newcomb, Peter T. Campbell, Wei Sun, Thomas J. Hudson, Ulrike Peters
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 1598.
DOI: https://doi.org/10.1158/1538-7445.AM2019-1598
Published: 01 July 2019
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Journal Articles

Abstract 1224: Deep targeted tumor sequencing of colorectal cancer cases to study associations of molecular subtypes with clinical, genetic, and lifestyle risk factors

Syed Zaidi, Amanda Phipps, Tabitha Harrison, Catherine Grasso, Robert Steinfelder, Quang Trinh, Charles Connolly, Barbara Banbury, Adilya Rafikova, Philipp Hofer, Stefanie Brezina, Marios Giannakis, Xinmeng Jasmine Mu, Michael Quist, Charles Fuchs, Levi Garraway, Li Hsu, Lincoln Stein, Andrea Gsur, Shuji Ogino, Steven Gallinger, Polly Newcomb, Peter Campbell, Wei Sun, Thomas Hudson, Ulrike Peters
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 1224.
DOI: https://doi.org/10.1158/1538-7445.AM2018-1224
Published: 01 July 2018
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Journal Articles

Abstract 1228: Comparative genomic analysis of young-onset and late-onset colorectal cancer

Jingqin Luo, Marios Giannakis, Graham Colditz, Jean Wang, William Chapman, Adetunji T. Toriola, Yoshiko Mito, Reiko Nishihara, Jonathan Nowak, Charles Fuchs, Edward Giovannucci, Andrew T. Chan, Adam Bass, Shuji Ogino, Ryan Fields, Yin Cao
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 1228.
DOI: https://doi.org/10.1158/1538-7445.AM2018-1228
Published: 01 July 2018
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Journal Articles

Abstract CT175: Biomarker analyses from a phase I study of WNT974, a first-in-class Porcupine inhibitor, in patients (pts) with advanced solid tumors

Jordi Rodon, Guillem Argilés, Roisin M. Connolly, Ulka Vaishampayan, Maja de Jonge, Elena Garralda, Marios Giannakis, David C. Smith, Jason R. Dobson, Margaret McLaughlin, Abdelkader Seroutou, Yan Ji, Sinead Dolan, Jennifer Morawiak, Susan Moody, Filip Janku
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): CT175.
DOI: https://doi.org/10.1158/1538-7445.AM2018-CT175
Published: 01 July 2018
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Journal Articles

Abstract 693: Calcium intake and risk of colorectal cancer according to tumor-infiltrating T cells: Results from two large U.S. prospective cohorts

Wanshui Yang, Li Liu, NaNa Keum, Zhi Rong Qian, Jonathan A. Nowak, Tsuyoshi Hamada, Mingyang Song, Yin Cao, Katsuhiko Nosho, Stephanie A. Smith-Warner, Shui Zhang, Yohei Masugi, Kimmie Ng, Keisuke Kosumi, Yanan Ma, Wendy S. Garrett, Molin Wang, Hongmei Nan, Marios Giannakis, Jeffrey A. Meyerhardt, Andrew T. Chan, Charles S. Fuchs, Reiko Nishihara, Kana Wu, Edward L. Giovannucci, Shuji Ogino, Xuehong Zhang
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 693.
DOI: https://doi.org/10.1158/1538-7445.AM2018-693
Published: 01 July 2018
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Journal Articles

Abstract 1286: Targeted deep sequencing of colorectal tumor tissues to study associations of tumor subtypes with germline genetic, lifestyle, and environmental risk factors

Syed H. Zaidi, Wei Sun, Jeroen Huyghe, Catherine S. Grasso, Quang Trinh, Charles Connolly, Amy French, Jasmine Mu, Marios Giannakis, Eve Shinbrot, Ivan Borozan, Michael J. Quist, Hermann Brenner, Daniel Buchanan, Peter Campbell, Andrew Chan, Jenny Chang-Claude, Vincent Ferretti, Charles Fuchs, Andrea Gsur, Marc Gunter, Tabitha Harrison, Michael Hoffmeister, Wen-Yi Huang, Paul Krzyzanowski, Stephen Lee, Mathieu Lemire, Jessica Miller, Danielle Pasternack, Cherie Teney, Elaine Mardis, Polly Newcomb, Lincoln Stein, Lee Timms, David Wheeler, Christina Yung, Niha Zubair, Levi Garraway, Shuji Ogino, Li Hsu, Steven Gallinger, Stephen Thibodeau, Thomas Hudson, Ulrike Peters
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1286.
DOI: https://doi.org/10.1158/1538-7445.AM2017-1286
Published: 01 July 2017
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Journal Articles

Abstract 4560: Fusobacterium nucleatum and tumor immunity status according to microsatellite instability in colorectal cancer

Kosuke Mima, Tsuyoshi Hamada, Reiko Nishihara, Jonathan Nowak, Zhi Rong Qian, Keisuke Kosumi, Marios Giannakis, Susan Bullman, Hideo Baba, Curtis Huttenhower, Wendy Garrett, Andrew Chan, Matthew Meyerson, Charles Fuchs, Shuji Ogino
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 4560.
DOI: https://doi.org/10.1158/1538-7445.AM2017-4560
Published: 01 July 2017
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Journal Articles

Precancer Atlas to Drive Precision Prevention Trials

Avrum Spira, Matthew B. Yurgelun, Ludmil Alexandrov, Anjana Rao, Rafael Bejar, Kornelia Polyak, Marios Giannakis, Ali Shilatifard, Olivera J. Finn, Madhav Dhodapkar, Neil E. Kay, Esteban Braggio, Eduardo Vilar, Sarah A. Mazzilli, Timothy R. Rebbeck, Judy E. Garber, Victor E. Velculescu, Mary L. Disis, Douglas C. Wallace, Scott M. Lippman
Journal: Cancer Research
Cancer Res (2017) 77 (7): 1510–1541.
DOI: https://doi.org/10.1158/0008-5472.CAN-16-2346
Published: 02 April 2017
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Journal Articles

Abstract PR01: Fusobacterium nucleatum and mutational landscape of colorectal cancer in whole-exome sequencing analysis

Reiko Nishihara, Andrew T. Chan, Jasmine Xinmeng Mu, Marios Giannakis, Kosuke Mima, Zhi Rong Qian, Susan Bullman, Aleksandar D. Kostic, Curtis Huttenhower, Wendy Garrett, Edward L. Giovannucci, Matthew Meyerson, Levi A. Garraway, Charles S. Fuchs, Shuji Ogino
Journal: Cancer Research
Cancer Res (2017) 77 (3_Supplement): PR01.
DOI: https://doi.org/10.1158/1538-7445.CRC16-PR01
Published: 31 January 2017
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Journal Articles

Abstract 136: Refining the molecular profile of colorectal tumors to expand prevention and treatment opportunities

Catherine S. Grasso, Eve Shinbrot, Ming Yu, Max Liesersen, Mark Chaisson, Andrew Chan, Charles Connolly, James Dai, Margaret Du, Charles Fuchs, Levi Garraway, Marios Giannakis, Tabitha Harrison, Li Hsu, Jeroen Huyghe, Jasmine Mu, Shuji Ogino, Colin Pritchard, Stephen Salipante, Wei Sun, Syed H. Zaidi, Ni Zhao, William Grady, Ben Raphael, Thomas Hudson, David Wheeler, Ulrike Peters
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 136.
DOI: https://doi.org/10.1158/1538-7445.AM2016-136
Published: 15 July 2016
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Abstract 5221: Linking the molecular profile of colorectal tumors to germline genetic and environmental risk factors

Syed H. Zaidi, Catie Grasso, Jasmine Mu, Eve Shinbrot, Marios Giannakis, Charles Connolly, Ivan Borozan, Hermann Brenner, Peter Campbell, Andrew Chan, Jenny Chang-Claude, Mengmeng Du, Vincent Ferretti, Amy French, Charles Fuchs, Steven Gallinger, Levi Garraway, Andrea Gsur, Marc Gunter, Tabitha Harrison, Michael Hoffmeister, Li Hsu, Wen-Yi Huang, Jeroen Huyghe, Mathieu Lemire, Elaine Mardis, John McPherson, Polly Newcomb, Lincoln Stein, Wei Sun, Lee Timms, Quang Trinh, David Wheeler, Christina Yung, Niha Zubair, Shuji Ogino, Stephen Thibodeau, Ulrike Peters, Thomas Hudson
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 5221.
DOI: https://doi.org/10.1158/1538-7445.AM2016-5221
Published: 15 July 2016
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