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Marie Evangelista
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Journal Articles

Abstract 3601: Discovery of novel dual-acting KRASG12C inhibitors that target both the active and inactive forms of the protein

Philamer Calses, Sam Clark, Jacob Corpuz, Susan Fong, Phil Gerkin, Mohammad Hekmatnejad, Evan McMahon, Megan Murray, Truc Nguyen, Tony Phan, Allison Roberts, Phillip Schwartz, Mikayla Shanafelt, Hiroko Tanaka, Jennifer Tomczyk, John Widen, Monika Williams, John Eksterowicz, Daniel Erlanson, Marie Evangelista, Johannes Hermann, Richard M. Neve, Snahel Patel, Kevin R. Webster
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 3601.
DOI: https://doi.org/10.1158/1538-7445.AM2022-3601
Published: 15 June 2022
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Journal Articles

Abstract 3327: Discovery and characterization of the potent, allosteric SHP2 inhibitor GDC-1971 for the treatment of RTK/RAS driven tumors

Bret Williams, Alexander Taylor, Olivia Orozco, Christopher Owen, Elizabeth Kelley, Andre Lescarbeau, Kelley Shortsleeves, Randy Kipp, Vy Nguyen, Erin Brophy, Jeremy Wilbur, Yong Tang, David Lanzetta, Nigel Waters, Sherri Smith, Fabrizio Giordanetto, Paul Maragakis, Jack Greismann, Lindsay Willmore, Eric Therrien, Yang Xiao, Marie Evangelista, Luca Gerosa, Eva Lin, Mark Merchant, Alfonso Arrazate, Emily Chan, Pablo Sáenz-López Larrocha, Stefan Chun, Thomas Hunsaker, Gauri Deshmukh, Christine M. Bowman, David E. Shaw, Mark Murcko, Mahesh Padval, W Patrick Walters, James Watters, Donald A. Bergstrom
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 3327.
DOI: https://doi.org/10.1158/1538-7445.AM2022-3327
Published: 15 June 2022
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Journal Articles

Abstract 2917: High complexity molecular indexing reveals that time-dependent cell plasticity underpins response to EGFR targeted therapy

Aaron Boudreau, Richard Bourgon, Marie Evangelista
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 2917.
DOI: https://doi.org/10.1158/1538-7445.AM2017-2917
Published: 01 July 2017
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Journal Articles

Abstract CT139: Phase I study of GDC-0425, a checkpoint kinase 1 inhibitor, in combination with gemcitabine in patients with refractory solid tumors

Jeffrey R. Infante, Antoine Hollebecque, Sophie Postel-Vinay, Todd Bauer, Beth Blackwood, Marie Evangelista, Sami Mahrus, Frank Peale, Xuyang Lu, Srikumar Sahasranaman, Rui Zhu, Yuan Chen, Xiao Ding, Elaine Murray, Jennifer Schutzman, Jennifer Lauchle, Jean-Charles Soria, Patricia LoRusso
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): CT139.
DOI: https://doi.org/10.1158/1538-7445.AM2015-CT139
Published: 01 August 2015
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Journal Articles

Abstract 944: Development of predictive and pharmacodynamic biomarker strategies for GDC-0425, a checkpoint kinase 1 inhibitor, in combination with gemcitabine

Sami Mahrus, Kelly DuPree, Kaska Kowanetz, Jenille Tan, Jarrod Tremayne, Diana Jakubiak, Peter Haverty, Yuda Zhu, Franklin Peale, Elizabeth Blackwood, Richard Bourgon, Robert Yauch, Mark Lackner, Marie Evangelista
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 944.
DOI: https://doi.org/10.1158/1538-7445.AM2015-944
Published: 01 August 2015
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Journal Articles

Abstract 964: Inhibiting glycolysis with an LDHA inhibitor: A new solution to an old problem

Thomas O'Brien, Hans Purkey, Anna Hitz, Dave Peterson, Aaron Boudreau, Christopher Delnagro, Mandy Kwong, Rebecca Hong, Min Gao, Jodi Pang, Alex Vanderbilt, Simon Williams, Laurent Salphati, Deepak Sampath, Georgia Hatzivassiliou, Marie Evangelista
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 964.
DOI: https://doi.org/10.1158/1538-7445.AM2014-964
Published: 01 October 2014
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Journal Articles

Abstract 1423: Resistance to LDHA inhibitors requires signaling through the AMPK/mTOR/S6K pathway leading to increased oxidative phosphorylation

Aaron Boudreau, David Peterson, John Moffat, Bonnie Liu, Mandy Kwong, Min Gao, Hans Purkey, Thomas O'Brien, Georgia Hatzivassiliou, Anneleen Daemen, Marie Evangelista
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 1423.
DOI: https://doi.org/10.1158/1538-7445.AM2014-1423
Published: 01 October 2014
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Journal Articles

The Cancer Stem Cell Marker Aldehyde Dehydrogenase Is Required to Maintain a Drug-Tolerant Tumor Cell Subpopulation

Debasish Raha, Timothy R. Wilson, Jing Peng, David Peterson, Peng Yue, Marie Evangelista, Catherine Wilson, Mark Merchant, Jeff Settleman
Journal: Cancer Research
Cancer Res (2014) 74 (13): 3579–3590.
DOI: https://doi.org/10.1158/0008-5472.CAN-13-3456
Published: 30 June 2014
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Includes: Supplementary data
Journal Articles

Abstract 4618: Elucidating the role of distinct glutaminase isoforms in cancer.

Bonnie Liu, Kyung Song, Mandy Kwong, Min Gao, Rebecca Hong, Michelle Nannini, Deepak Sampath, Marcia Belvin, David Peterson, Marie Evangelista, Anneleen Daemen, Ron Firestein, Georgia Hatzivassiliou
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 4618.
DOI: https://doi.org/10.1158/1538-7445.AM2013-4618
Published: 15 April 2013
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Journal Articles

Abstract 943: RRM2: a key contributor in tamoxifen resistance in breast cancer.

Khyati Niral Shah, David Peterson, Marie Evangelista, Jesika Faridi
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 943.
DOI: https://doi.org/10.1158/1538-7445.AM2013-943
Published: 15 April 2013
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Journal Articles

An Integrated Genomic Screen Identifies LDHB as an Essential Gene for Triple-Negative Breast Cancer

Mark L. McCleland, Adam S. Adler, Yonglei Shang, Thomas Hunsaker, Tom Truong, David Peterson, Eric Torres, Li Li, Benjamin Haley, Jean-Philippe Stephan, Marcia Belvin, Georgia Hatzivassiliou, Elizabeth M. Blackwood, Laura Corson, Marie Evangelista, Jiping Zha, Ron Firestein
Journal: Cancer Research
Cancer Res (2012) 72 (22): 5812–5823.
DOI: https://doi.org/10.1158/0008-5472.CAN-12-1098
Published: 14 November 2012
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Includes: Supplementary data