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Journal Articles

Abstract 1431: ADO contributes to tumour initiating phenotypes

Sandy Che-Eun Serena Lee, Andrea Hye An Pyo, Marianne Koritzinsky

Cancer Res (2022) 82 (12_Supplement): 1431.

DOI: https://doi.org/10.1158/1538-7445.AM2022-1431

Published: 15 June 2022

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Journal Articles

Abstract 117: Therapeutic targeting of hypoxia tolerance and oxygen consumption in pancreatic cancer

Ji Zhang, Dan Cojocari, Pedro Boasquevisque, Mark Zaidi, Trevor McKee, Nikolina Radulovich, Ming-Sound Tsao, David Hedley, Marianne Koritzinsky, Bradley Wouters

Cancer Res (2022) 82 (12_Supplement): 117.

DOI: https://doi.org/10.1158/1538-7445.AM2022-117

Published: 15 June 2022

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Journal Articles

Abstract 124: PRDX4 links ER-specific redox vulnerability to innate immunity in pancreatic cancer

Lucie Malbeteau, Pallavi Jain, Shane Harding, Bradley Wouters, Marianne Koritzinsky

Cancer Res (2022) 82 (12_Supplement): 124.

DOI: https://doi.org/10.1158/1538-7445.AM2022-124

Published: 15 June 2022

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Journal Articles

Abstract 978: The potential role of microbiome in metastatic HNSCC

Maria Kondratyev, Aleksandra Pesic, Anna Dvorkin-Sheva, Marianne Koritzinsky, Bradly G. Wouters

Cancer Res (2022) 82 (12_Supplement): 978.

DOI: https://doi.org/10.1158/1538-7445.AM2022-978

Published: 15 June 2022

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Journal Articles

Abstract 2311: Identification of therapeutic targets in HNSCC

Maria Kondratyev, Aleksandra Pesic, Anna Dvorkin-Sheva, Troy Ketela, Natalie Stickle, Laurie Aiiles, Reidar Grenman, Marianne Koritzinsky, Brad Wouters

Cancer Res (2021) 81 (13_Supplement): 2311.

DOI: https://doi.org/10.1158/1538-7445.AM2021-2311

Published: 01 July 2021

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Journal Articles

Abstract 3559: Protein secretion rates of VEGF and CA9 in normoxia and hypoxia

Sandy Che-Eun Serena Lee, Fiana Levitin, Stephanie Hulme, Ryan Rumantir, Jenna Sykes, Marianne Koritzinsky

Cancer Res (2020) 80 (16_Supplement): 3559.

DOI: https://doi.org/10.1158/1538-7445.AM2020-3559

Published: 15 August 2020

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Journal Articles

Abstract 507: Repurposing of FDA approved drugs for treatment of metastatic HNSCC

Maria Kondratyev, Aleksandra Pesic, Anna Dvorkin-Sheva, Troy Ketela, Jason Moffat, Marianne Koritzinsky, Brad Wouters

Cancer Res (2020) 80 (16_Supplement): 507.

DOI: https://doi.org/10.1158/1538-7445.AM2020-507

Published: 15 August 2020

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Journal Articles

Abstract B10: Antibacterial defense and metastatic progression—lessons from head and neck cancer

Maria Kondratyev, Aleksandra Pesic, Carl Virtanen, Marianne Koritzinsky, Brad Wouters

Cancer Res (2020) 80 (8_Supplement): B10.

DOI: https://doi.org/10.1158/1538-7445.MVC2020-B10

Published: 15 April 2020

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Journal Articles

Modeling Cellular Response in Large-Scale Radiogenomic Databases to Advance Precision Radiotherapy

Venkata SK. Manem, Meghan Lambie, Ian Smith, Petr Smirnov, Victor Kofia, Mark Freeman, Marianne Koritzinsky, Mohamed E. Abazeed, Benjamin Haibe-Kains, Scott V. Bratman

Cancer Res (2019) 79 (24): 6227–6237.

DOI: https://doi.org/10.1158/0008-5472.CAN-19-0179

Published: 13 December 2019

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Includes: Supplementary data

Journal Articles

Abstract 883: PRDX4 as a novel target for pancreatic cancer

Pallavi Jain, Azin Sayad, Erik Mollen, Michael Xie, Kevin Brown, Jason Moffat, David Hedley, Paul Boutros, Bradley Wouters, Marianne Koritzinsky

Cancer Res (2019) 79 (13_Supplement): 883.

DOI: https://doi.org/10.1158/1538-7445.AM2019-883

Published: 01 July 2019

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Journal Articles

Abstract 3054: Cell surface targets in head and neck cancer

Maria Kondratyev, Aleksandra Pesic, Azin Sayad, Troy Ketela, Natalie Stickle, Carl Virtanen, Jason Moffat, Laurie Ailles, Marianne Koritzinsky, Brad Wouters

Cancer Res (2019) 79 (13_Supplement): 3054.

DOI: https://doi.org/10.1158/1538-7445.AM2019-3054

Published: 01 July 2019

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Journal Articles

Abstract 5476: Inhibiting lactate transporters MCT-1 and MCT-4 target hypoxic HNSCC cells and sensitize them to metformin

Pedro H. Boasquevisque, Verena Schoeneberger, Laura Caporiccio, Ravi Vellanki, Marianne Koritzinsky, Bradly G. Wouters

Cancer Res (2018) 78 (13_Supplement): 5476.

DOI: https://doi.org/10.1158/1538-7445.AM2018-5476

Published: 01 July 2018

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Journal Articles

Abstract 2443: Oxygen metabolism and hypoxia tolerance in organoid models of pancreatic ductal adenocarcinoma

Ji Zhang, Qingquan Liu, Dan Cojocari, Mark Zaidi, Trevor McKee, Nikolina Radulovich, Ming-Sound Tsao, David Hedley, Marianne Koritzinsky, Bradly G. Wouters

Cancer Res (2018) 78 (13_Supplement): 2443.

DOI: https://doi.org/10.1158/1538-7445.AM2018-2443

Published: 01 July 2018

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Journal Articles

Abstract 3020: Novel therapeutic targets in head and neck cancer

Maria Kondratyev, Aleksandra Pesic, Troy Ketela, Azin Sayad, Stephano Marastoni, Carl Virtanen, Laurie Ailles, Soroush Samadian, Mikhail Bashkurov, Marianne Koritzinsky, Brad Wouters

Cancer Res (2017) 77 (13_Supplement): 3020.

DOI: https://doi.org/10.1158/1538-7445.AM2017-3020

Published: 01 July 2017

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Journal Articles

Abstract 4499: The oncometabolite fumarate prevents hypoxia-induced ER stress by enhancing the pentose phosphate pathway

Luana Schito, Sergio Rey, Bradly G. Wouters, Marianne Koritzinsky

Cancer Res (2017) 77 (13_Supplement): 4499.

DOI: https://doi.org/10.1158/1538-7445.AM2017-4499

Published: 01 July 2017

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Journal Articles

Abstract 4510: ADP- dependent glucokinase controls hypoxic gradients, ex vivo avascular and in vivo tumor growth through modulation of HIF-1α/mTOR signaling

Sergio Rey, Luana Schito, Marianne Koritzinsky, Bradly G. Wouters

Cancer Res (2017) 77 (13_Supplement): 4510.

DOI: https://doi.org/10.1158/1538-7445.AM2017-4510

Published: 01 July 2017

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Journal Articles

Abstract 1031: Fumarate hydratase deficiency redirects glucose metabolism of hypoxic cancer cells into the pentose phosphate pathway

Luana Schito, Sergio Rey, Judy Pawling, James W. Dennis, Bradly G. Wouters, Marianne Koritzinsky

Cancer Res (2016) 76 (14_Supplement): 1031.

DOI: https://doi.org/10.1158/1538-7445.AM2016-1031

Published: 15 July 2016

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Journal Articles

Abstract 2793: ADP- dependent glucokinase enhances hypoxia- inducible factor-α target gene transactivation through modulation of ROS levels in hypoxic human cancer cells

Sergio Rey, Luana Schito, Marianne Koritzinsky, Bradly G. Wouters

Cancer Res (2016) 76 (14_Supplement): 2793.

DOI: https://doi.org/10.1158/1538-7445.AM2016-2793

Published: 15 July 2016

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Journal Articles

Abstract 3794: Novel therapeutic targets in head and neck cancer

Maria Kondratyev, Aleksandra Pesic, Stephano Marastoni, Troy Ketela, Jason Moffat, Carl Virtanen, Azin Sayad, Mikhail Bashkurov, Alessandro Dati, Laurie Ailles, Reidar Grenman, Marianne Koritzinsky, Brad Wouters

Cancer Res (2016) 76 (14_Supplement): 3794.

DOI: https://doi.org/10.1158/1538-7445.AM2016-3794

Published: 15 July 2016

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Journal Articles

Identification of P450 Oxidoreductase as a Major Determinant of Sensitivity to Hypoxia-Activated Prodrugs

Francis W. Hunter, Richard J. Young, Zvi Shalev, Ravi N. Vellanki, Jingli Wang, Yongchuan Gu, Naveen Joshi, Sreevalsan Sreebhavan, Ilan Weinreb, David P. Goldstein, Jason Moffat, Troy Ketela, Kevin R. Brown, Marianne Koritzinsky, Benjamin Solomon, Danny Rischin, William R. Wilson, Bradly G. Wouters

Cancer Res (2015) 75 (19): 4211–4223.

DOI: https://doi.org/10.1158/0008-5472.CAN-15-1107

Published: 30 September 2015

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Includes: Supplementary data

NARROW

Abstract 1431: ADO contributes to tumour initiating phenotypes

Abstract 117: Therapeutic targeting of hypoxia tolerance and oxygen consumption in pancreatic cancer

Abstract 124: PRDX4 links ER-specific redox vulnerability to innate immunity in pancreatic cancer

Abstract 978: The potential role of microbiome in metastatic HNSCC

Abstract 2311: Identification of therapeutic targets in HNSCC

Abstract 3559: Protein secretion rates of VEGF and CA9 in normoxia and hypoxia

Abstract 507: Repurposing of FDA approved drugs for treatment of metastatic HNSCC

Abstract B10: Antibacterial defense and metastatic progression—lessons from head and neck cancer

Modeling Cellular Response in Large-Scale Radiogenomic Databases to Advance Precision Radiotherapy

Abstract 883: PRDX4 as a novel target for pancreatic cancer

Abstract 3054: Cell surface targets in head and neck cancer

Abstract 5476: Inhibiting lactate transporters MCT-1 and MCT-4 target hypoxic HNSCC cells and sensitize them to metformin

Abstract 2443: Oxygen metabolism and hypoxia tolerance in organoid models of pancreatic ductal adenocarcinoma

Abstract 3020: Novel therapeutic targets in head and neck cancer

Abstract 4499: The oncometabolite fumarate prevents hypoxia-induced ER stress by enhancing the pentose phosphate pathway

Abstract 4510: ADP- dependent glucokinase controls hypoxic gradients, ex vivo avascular and in vivo tumor growth through modulation of HIF-1α/mTOR signaling

Abstract 1031: Fumarate hydratase deficiency redirects glucose metabolism of hypoxic cancer cells into the pentose phosphate pathway

Abstract 2793: ADP- dependent glucokinase enhances hypoxia- inducible factor-α target gene transactivation through modulation of ROS levels in hypoxic human cancer cells

Abstract 3794: Novel therapeutic targets in head and neck cancer

Identification of P450 Oxidoreductase as a Major Determinant of Sensitivity to Hypoxia-Activated Prodrugs

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