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Journal Articles

Abstract 692: Patient-derived co-cultures of TRACERx lung cancer organoids and autologous T-cells reveal heterogeneity in immune evasion between cancer subclones

Cancer Res (2022) 82 (12_Supplement): 692.

DOI: https://doi.org/10.1158/1538-7445.AM2022-692

Published: 15 June 2022

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Journal Articles

Abstract SY39-03: Lung cancer evolution and its prognostic impact

Mariam Jamal-Hanjani

Cancer Res (2022) 82 (12_Supplement): SY39-03.

DOI: https://doi.org/10.1158/1538-7445.AM2022-SY39-03

Published: 15 June 2022

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Journal Articles

Abstract 3096: Multi-region patient-derived xenograft models from non-small cell lung cancer patients enrolled in lung TRACERx

Robert E. Hynds, David R. Pearce, Ayse U. Akarca, Sophia Ward, Ariana Huebner, Oriol Pich, Gareth A. Wilson, Kate H. Gowers, Rebecca Towns, Assma Ben Aissa, Selvaraju Veeriah, Sergio A. Quezada, Mariam Jamal-Hanjani, Sam M. Janes, Nicholas McGranahan, David A. Moore, Teresa Marafioti, Charles Swanton

Cancer Res (2022) 82 (12_Supplement): 3096.

DOI: https://doi.org/10.1158/1538-7445.AM2022-3096

Published: 15 June 2022

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Journal Articles

Abstract 3792: TRACERx: Mapping the evolution of metastases in non-small cell lung cancer

Cancer Res (2022) 82 (12_Supplement): 3792.

DOI: https://doi.org/10.1158/1538-7445.AM2022-3792

Published: 15 June 2022

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Journal Articles

Abstract 5818: Features of cancer cachexia in non-small cell lung cancer: Insights from the prospective TRACERx study

Othman Al-Sawaf, Marcin Skrzypski, Jakob Weiss, Takahiro Karasaki, Nicolai Juul Birkbak, Francisco Zambrana, Alexander Frankell, Thomas B. Watkins, Carlos Martinez Ruiz, Selvaraju Veeriah, Cristina Naceur-Lombardelli, TRACERx Consortium, Nicholas McGranahan, Hugo Aerts, Charles Swanton, Mariam Jamal-Hanjani

Cancer Res (2022) 82 (12_Supplement): 5818.

DOI: https://doi.org/10.1158/1538-7445.AM2022-5818

Published: 15 June 2022

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Journal Articles

Abstract 645: Heterogeneity of immunotherapy biomarkers in the TRACERx non-small cell lung cancer multi-region lung cancer cohort study

Cancer Res (2022) 82 (12_Supplement): 645.

DOI: https://doi.org/10.1158/1538-7445.AM2022-645

Published: 15 June 2022

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Journal Articles

Abstract LB064: B cells synergize with T cell regulation at immune hotspots in lung squamous cell carcinoma

Hanyun Zhang, Khalid AbdulJabbar, David A. Moore, Ayse Akarca, Katey Enfield, Mariam Jamal-Hanjani, Shan E Ahmed Raza, Selvaraju Veeriah, Dhruva Biswas, Roberto Salgado, Nicholas McGranahan, TRACERx Consortium, John Le Quesne, Charles Swanton, Teresa Marafioti, Yinyin Yuan

Cancer Res (2022) 82 (12_Supplement): LB064.

DOI: https://doi.org/10.1158/1538-7445.AM2022-LB064

Published: 15 June 2022

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Journal Articles

Abstract 204: Notch2NL is a novel regulator of radiation sensitivity in non-small cell lung cancer and a positive regulator of MYC activity

Simranpreet Kaur Summan, Barbara Chow, Rhona Millar, Su Kit Chew, Philip East, Robert Hynds, Carlos Martinez Ruiz, Eva Gronroos, Mariam Jamal-Hanjani, Kevin Litchfield, Nicholas McGranahan, Nnennaya Kanu, Charles Swanton, Crispin Thomas Hiley

Cancer Res (2022) 82 (12_Supplement): 204.

DOI: https://doi.org/10.1158/1538-7445.AM2022-204

Published: 15 June 2022

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Journal Articles

Abstract 3626: Genomic evolutionary patterns in matched pre-invasive and invasive lung disease in TRACERx

Haoran Zhai, Clare Puttick, David A. Moore, Michelle Dietzen, Sophia Ward, Maise Al Bakir, Thomas Watkins, Andrew Rowan, Selvaraju Veeriah, Robert Hynds, Oriol Pich, Nnennaya Kanu, TRACERx Consortium, Nicholas McGranahan, Charles Swanton, Mariam Jamal-Hanjani

Cancer Res (2022) 82 (12_Supplement): 3626.

DOI: https://doi.org/10.1158/1538-7445.AM2022-3626

Published: 15 June 2022

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Journal Articles

Abstract 5636: V-delta-1 T cells are resident in the human lung and associate with survival in patients with non-small cell lung cancer in the TRACERx Study

Yin Wu, Dhruva Biswas, Ieva Usaite, Angelova Mihaela, Stefan Boeing, Takahiro Karasaki, Selvaraju Veeriah, Justyna Czyzewska-Khan, James Reading, Andrew Georgiou, Maise Al-Bakir, Nicholas McGranahan, Mariam Jamal-Hanjani, Allan Hackshaw, TRACERx Consortium, Sergio Quezada, Adrian Hayday, Charles Swanton

Cancer Res (2022) 82 (12_Supplement): 5636.

DOI: https://doi.org/10.1158/1538-7445.AM2022-5636

Published: 15 June 2022

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Journal Articles

Abstract 6080: The heterogeneity and evolution of lung neuroendocrine tumors within TRACERx

Robert Bentham, David A. Moore, Lorelle Brownlee, Raju Veeriah, Lizi Manzano, Fiona Blackhall, Colin R. Lindsay, TRACERx Consortium, Nicholas McGranahan, Charles Swanton, Mariam Jamal-Hanjani

Cancer Res (2022) 82 (12_Supplement): 6080.

DOI: https://doi.org/10.1158/1538-7445.AM2022-6080

Published: 15 June 2022

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Journal Articles

Abstract 6091: Evolutionary characterisation of lung adenocarcinoma pathological subtypes in TRACERx

Cancer Res (2022) 82 (12_Supplement): 6091.

DOI: https://doi.org/10.1158/1538-7445.AM2022-6091

Published: 15 June 2022

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Journal Articles

Abstract 1603: Genomic transcriptomic evolution in TRACERx lung cancer and metastasis

Cancer Res (2022) 82 (12_Supplement): 1603.

DOI: https://doi.org/10.1158/1538-7445.AM2022-1603

Published: 15 June 2022

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Journal Articles

Abstract 1926: Machine learning-enhanced image and spatial analytic pipelines for imaging mass cytometry applied to the TRACERx non-small cell lung cancer study

Alastair Magness, Katey Enfield, Mihaela Angelova, Emma Colliver, Emer Daly, Kristiana Grigoriadis, Claudia Lee, Oriol Pich, Philip Hobson, Dina Levi, Takahiro Karasaki, David Moore, Julian Downward, Erik Sahai, Mariam Jamal-Hanjani, Charles Swanton, TRACERx Consortium

Cancer Res (2022) 82 (12_Supplement): 1926.

DOI: https://doi.org/10.1158/1538-7445.AM2022-1926

Published: 15 June 2022

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Journal Articles

Abstract 3609: Defining extrinsic and intrinsic mechanisms of immune evasion in TRACERx using imaging mass cytometry

Cancer Res (2022) 82 (12_Supplement): 3609.

DOI: https://doi.org/10.1158/1538-7445.AM2022-3609

Published: 15 June 2022

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Journal Articles

Abstract 2144: Holistic sampling of clonal dynamics using cfDNA in lung TRACERx

Cancer Res (2022) 82 (12_Supplement): 2144.

DOI: https://doi.org/10.1158/1538-7445.AM2022-2144

Published: 15 June 2022

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Journal Articles

Abstract 1394: Pervasive allele specific transcriptional repression of the class I and II HLA genes in TRACERx non-small cell lung cancer

Cancer Res (2022) 82 (12_Supplement): 1394.

DOI: https://doi.org/10.1158/1538-7445.AM2022-1394

Published: 15 June 2022

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Journal Articles

Abstract A012: Advanced melanoma exhibits a diversity of evolutionary routes to lethality

Cancer Res (2022) 82 (10_Supplement): A012.

DOI: https://doi.org/10.1158/1538-7445.EVODYN22-A012

Published: 15 May 2022

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Journal Articles

Abstract PR002: Advanced melanoma exhibits a diversity of evolutionary routes to lethality

Cancer Res (2022) 82 (10_Supplement): PR002.

DOI: https://doi.org/10.1158/1538-7445.EVODYN22-PR002

Published: 15 May 2022

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Journal Articles

Abstract 1508: Characterization of a novel clonal neoantigen reactive T cell (cNeT) product through a comprehensive translational research program

Cancer Res (2021) 81 (13_Supplement): 1508.

DOI: https://doi.org/10.1158/1538-7445.AM2021-1508

Published: 01 July 2021

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NARROW

Abstract 692: Patient-derived co-cultures of TRACERx lung cancer organoids and autologous T-cells reveal heterogeneity in immune evasion between cancer subclones

Abstract SY39-03: Lung cancer evolution and its prognostic impact

Abstract 3096: Multi-region patient-derived xenograft models from non-small cell lung cancer patients enrolled in lung TRACERx

Abstract 3792: TRACERx: Mapping the evolution of metastases in non-small cell lung cancer

Abstract 5818: Features of cancer cachexia in non-small cell lung cancer: Insights from the prospective TRACERx study

Abstract 645: Heterogeneity of immunotherapy biomarkers in the TRACERx non-small cell lung cancer multi-region lung cancer cohort study

Abstract LB064: B cells synergize with T cell regulation at immune hotspots in lung squamous cell carcinoma

Abstract 204: Notch2NL is a novel regulator of radiation sensitivity in non-small cell lung cancer and a positive regulator of MYC activity

Abstract 3626: Genomic evolutionary patterns in matched pre-invasive and invasive lung disease in TRACERx

Abstract 5636: V-delta-1 T cells are resident in the human lung and associate with survival in patients with non-small cell lung cancer in the TRACERx Study

Abstract 6080: The heterogeneity and evolution of lung neuroendocrine tumors within TRACERx

Abstract 6091: Evolutionary characterisation of lung adenocarcinoma pathological subtypes in TRACERx

Abstract 1603: Genomic transcriptomic evolution in TRACERx lung cancer and metastasis

Abstract 1926: Machine learning-enhanced image and spatial analytic pipelines for imaging mass cytometry applied to the TRACERx non-small cell lung cancer study

Abstract 3609: Defining extrinsic and intrinsic mechanisms of immune evasion in TRACERx using imaging mass cytometry

Abstract 2144: Holistic sampling of clonal dynamics using cfDNA in lung TRACERx

Abstract 1394: Pervasive allele specific transcriptional repression of the class I and II HLA genes in TRACERx non-small cell lung cancer

Abstract A012: Advanced melanoma exhibits a diversity of evolutionary routes to lethality

Abstract PR002: Advanced melanoma exhibits a diversity of evolutionary routes to lethality

Abstract 1508: Characterization of a novel clonal neoantigen reactive T cell (cNeT) product through a comprehensive translational research program

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