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Journal Articles

Abstract 2736: Genetic deletion of the prkar1a in the endocrine pancreas promotes neuroendocrine carcinogenesis.

Emmanouil Saloustros, Maria Tsokos, Paraskevi Salpea, Matthew Starost, Sisi Liu, Li Guang, Maria Nesterova, Eva Szarek, Mehboob A. Hussain, Constantine A. Stratakis
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 2736.
https://doi.org/10.1158/1538-7445.AM2013-2736
Published: 15 April 2013
View article titled, Abstract 2736: Genetic deletion of the prkar1a in the endocrine pancreas promotes neuroendocrine carcinogenesis.
Journal Articles

Abstract 2963: Succinate dehydrogenase mutation underlies global epigenomic divergence in gastrointestinal stromal tumor.

Paul S. Meltzer, J. Keith Killian, Su Young Kim, Markku Miettinen, Carly Smith, Maria Tsokos, Martha Quezado, William I. Smith, Mona S. Jahromi, Robert L. Walker, Jerzy Lasota, Brandy Klotzle, Zengfeng Wang, Laura Jones, Yuelin Zhu, Yonghong Wang, Joshua J. Waterfall, Marina Bibikova, Maureen J. O'Sullivan, Constantine A. Stratakis, Joshua D. Schiffman, Jian-Bing Fan, Lee Helman
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 2963.
https://doi.org/10.1158/1538-7445.AM2013-2963
Published: 15 April 2013
View article titled, Abstract 2963: Succinate dehydrogenase mutation underlies global epigenomic divergence in gastrointestinal stromal tumor.
Journal Articles

Abstract 3551: CD44 expression in Ewing sarcoma is associated with reduced chemosensitivity in vitro.

Nikolina Dioufa, Guang Li, Maria Tsokos
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 3551.
https://doi.org/10.1158/1538-7445.AM2013-3551
Published: 15 April 2013
View article titled, Abstract 3551: CD44 expression in Ewing sarcoma is associated with reduced chemosensitivity in vitro.
Journal Articles

Abstract 960: Ceramide-dependent release of nanovesicles is a class effect oflipid-based Akt inhibitors

Joell J. Gills, Chunyu Zhang, Mones S. Abu-Asab, S. Sianna Castillo, Caleb Marceau, Alan Kozikowski, Maria Tsokos, Tzipora Goldkorn, Phillip A. Dennis
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 960.
https://doi.org/10.1158/1538-7445.AM2011-960
Published: 15 April 2011
View article titled, Abstract 960: Ceramide-dependent release of nanovesicles is a class effect oflipid-based Akt inhibitors
Journal Articles

Thrombospondin 1 Promotes Tumor Macrophage Recruitment and Enhances Tumor Cell Cytotoxicity of Differentiated U937 Cells

Gema Martin-Manso, Susana Galli, Lisa A. Ridnour, Maria Tsokos, David A. Wink, David D. Roberts
Journal: Cancer Research
Cancer Res (2008) 68 (17): 7090–7099.
https://doi.org/10.1158/0008-5472.CAN-08-0643
Published: 28 August 2008
View article titled, Thrombospondin 1 Promotes Tumor Macrophage Recruitment and Enhances Tumor Cell Cytotoxicity of Differentiated U937 Cells
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Journal Articles

Lipid-based Akt inhibitors cause secretion of active Akt, EGFR and IGF-IR in tetraspanin-enriched nanovesicles

Joell Gills, Mones Abu-Asab, Jaclyn LoPiccolo, Maria Tsokos, Alice Crane, Phillip Dennis
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 1466.
Published: 01 May 2008
View article titled, Lipid-based Akt inhibitors cause secretion of active Akt, EGFR and IGF-IR in tetraspanin-enriched nanovesicles
Journal Articles

XIAP silencing with RNA interference does not enhance sensitivity of Ewing sarcoma cell lines to TNF-related apoptotic inducing ligand (TRAIL).

Maria-Teresa Demarco, Susana Galli, Guang Li, Maria Tsokos
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 829.
Published: 01 May 2008
View article titled, XIAP silencing with RNA interference does not enhance sensitivity of Ewing sarcoma cell lines to TNF-related apoptotic inducing ligand (TRAIL).
Journal Articles

Survivin overexpression contributes to TRAIL resistance of Ewing Sarcoma Family Tumor (ESFT) cells with low caspase 8 expression.

Guang Li, Yan Ren, Susana Galli, Maria Tsokos
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 3376.
Published: 01 May 2008
View article titled, Survivin overexpression contributes to TRAIL resistance of Ewing Sarcoma Family Tumor (ESFT) cells with low caspase 8 expression.
Journal Articles

Targeting of EWS/FLi-1 by siRNA inhibits survivin expression and sensitizes ESFT cells to TRAIL

Guang Li, Maria Tsokos
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 522.
Published: 01 May 2007
View article titled, Targeting of EWS/FLi-1 by siRNA inhibits survivin expression and sensitizes ESFT cells to TRAIL
Journal Articles

Phosphoprotein Pathway Mapping: Akt/Mammalian Target of Rapamycin Activation Is Negatively Associated with Childhood Rhabdomyosarcoma Survival

Emanuel F. Petricoin, III, Virginia Espina, Robyn P. Araujo, Brieanne Midura, Choh Yeung, Xiaolin Wan, Gabriel S. Eichler, Donald J. Johann, Jr., Stephen Qualman, Maria Tsokos, Kartik Krishnan, Lee J. Helman, Lance A. Liotta
Journal: Cancer Research
Cancer Res (2007) 67 (7): 3431–3440.
https://doi.org/10.1158/0008-5472.CAN-06-1344
Published: 04 April 2007
View article titled, Phosphoprotein Pathway Mapping: Akt/Mammalian Target of Rapamycin Activation Is Negatively Associated with Childhood Rhabdomyosarcoma Survival
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Includes: Supplementary data
Journal Articles

Phosphoproteomic profiling identifies 4EBP1 and phosphorylated eIF4E as prognostic indicators as well as new drug targets in therapy resistant childhood Rhabdomyosarcoma

Virginia A. Espina, Choh Yeung, Gabriel Eichler, Kartik Krishnan, Brieanne Midura, Maria Tsokos, Stephen J. Qualman, William H. Meyer, Emanuel F. Petricoin, III, Lee J. Helman, Lance A. Liotta
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 1025.
Published: 01 May 2005
View article titled, Phosphoproteomic profiling identifies 4EBP1 and phosphorylated eIF4E as prognostic indicators as well as new drug targets in therapy resistant childhood Rhabdomyosarcoma
Journal Articles

Interferon γ Enhances the Effectiveness of Tumor Necrosis Factor-Related Apoptosis–Inducing Ligand Receptor Agonists in a Xenograft Model of Ewing’s Sarcoma

Melinda S. Merchant, Xuezhong Yang, Fraia Melchionda, Maria Romero, Ruth Klein, Carol J. Thiele, Maria Tsokos, H. Udo Kontny, Crystal L. Mackall
Journal: Cancer Research
Cancer Res (2004) 64 (22): 8349–8356.
https://doi.org/10.1158/0008-5472.CAN-04-1705
Published: 17 November 2004
View article titled, Interferon γ Enhances the Effectiveness of Tumor Necrosis Factor-Related Apoptosis–Inducing Ligand Receptor Agonists in a Xenograft Model of Ewing’s Sarcoma
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Journal Articles

Downregulation of the bifunctional apoptosis regulator (BAR) reverses TRAIL resistance in neuroblastoma cells

Maria E. Romero, Wen-Shuz Yeow, Maria Tsokos
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 1287.
Published: 01 April 2004
View article titled, Downregulation of the bifunctional apoptosis regulator (BAR) reverses TRAIL resistance in neuroblastoma cells
Journal Articles

Anti-metastatic effects of a TRAIL receptor agonist and interferon gamma in an orthotopic xenograft model of Ewing’s sarcoma

Melinda S. Merchant, Maria Romero, Fraia Melchionda, Maria Tsokos, Crystal L. Mackall
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 1076.
Published: 01 April 2004
View article titled, Anti-metastatic effects of a TRAIL receptor agonist and interferon gamma in an orthotopic xenograft model of Ewing’s sarcoma
Journal Articles

Induction of Caspase 8 by Interferon γ Renders Some Neuroblastoma (NB) Cells Sensitive to Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL) but Reveals That a Lack of Membrane TR1/TR2 Also Contributes to TRAIL Resistance in NB

Xuezhong Yang, Melinda S. Merchant, Maria E. Romero, Maria Tsokos, Leonard H. Wexler, Udo Kontny, Crystal L. Mackall, Carol J. Thiele
Journal: Cancer Research
Cancer Res (2003) 63 (5): 1122–1129.
Published: 01 March 2003
View article titled, Induction of Caspase 8 by Interferon γ Renders Some Neuroblastoma (NB) Cells Sensitive to Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL) but Reveals That a Lack of Membrane TR1/TR2 Also Contributes to TRAIL Resistance in NB
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Journal Articles

Fas-mediated Apoptosis in Neuroblastoma Requires Mitochondrial Activation and Is Inhibited by FLICE Inhibitor Protein and bcl-2

Vassiliki Poulaki, Nicholas Mitsiades, Maria E. Romero, Maria Tsokos
Journal: Cancer Research
Cancer Res (2001) 61 (12): 4864–4872.
Published: 01 June 2001
View article titled, Fas-mediated Apoptosis in Neuroblastoma Requires Mitochondrial Activation and Is Inhibited by FLICE Inhibitor Protein and bcl-2
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Journal Articles

Ewing’s Sarcoma Family Tumors Are Sensitive to Tumor Necrosis Factor-related Apoptosis-inducing Ligand and Express Death Receptor 4 and Death Receptor 5

Nicholas Mitsiades, Vassiliki Poulaki, Constantine Mitsiades, Maria Tsokos
Journal: Cancer Research
Cancer Res (2001) 61 (6): 2704–2712.
Published: 03 March 2001
View article titled, Ewing’s Sarcoma Family Tumors Are Sensitive to Tumor Necrosis Factor-related Apoptosis-inducing Ligand and Express Death Receptor 4 and Death Receptor 5
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Journal Articles

Matrix Metalloproteinase-7-mediated Cleavage of Fas Ligand Protects Tumor Cells from Chemotherapeutic Drug Cytotoxicity

Nicholas Mitsiades, Wei-hsuan Yu, Vassiliki Poulaki, Maria Tsokos, Ivan Stamenkovic
Journal: Cancer Research
Cancer Res (2001) 61 (2): 577–581.
Published: 01 January 2001
View article titled, Matrix Metalloproteinase-7-mediated Cleavage of Fas Ligand Protects Tumor Cells from Chemotherapeutic Drug Cytotoxicity
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Journal Articles

Pluripotent Tumor Cells in Benign Pituitary Adenomas Associated with Multiple Endocrine Neoplasia Type 1

Robert J. Weil, Steve Huang, Svetlana Pack, Alexander O. Vortmeyer, Maria Tsokos, Irina A. Lubensky, Edward H. Oldfield, Zhengping Zhuang
Journal: Cancer Research
Cancer Res (1998) 58 (20): 4715–4720.
Published: 01 October 1998
View article titled, Pluripotent Tumor Cells in Benign Pituitary Adenomas Associated with Multiple Endocrine Neoplasia Type 1
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Journal Articles

Stimulation of Tumor Growth by Recombinant Human Insulin-like Growth Factor-I (IGF-I) Is Dependent on the Dose and the Level of IGF-I Receptor Expression

Andrew A. Butler, Vicky A. Blakesley, Maria Tsokos, Vasiliki Pouliki, Teresa L. Wood, Derek LeRoith
Journal: Cancer Research
Cancer Res (1998) 58 (14): 3021–3027.
Published: 01 July 1998
View article titled, Stimulation of Tumor Growth by Recombinant Human Insulin-like Growth Factor-I (IGF-I) Is Dependent on the Dose and the Level of IGF-I Receptor Expression
Open the PDF for Stimulation of Tumor Growth by Recombinant Human Insulin-like Growth Factor-I (IGF-I) Is Dependent on the Dose and the Level of IGF-I Receptor Expression in another window