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Maria Teresa Landi
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Journal Articles

Abstract 865: Genomic and evolutionary classification of lung cancer in never smokers from the Sherlock-Lung study

Tongwu Zhang, Ludmil B. Alexandrov, Wei Zhao, Jian Sang, Jianxin Shi, Bin Zhu, Dmitry A. Gordenin, Montserrat Garcia-Closas, Qing Lan, Nathaniel Rothman, Stephen J. Chanock, David C. Wedge, Maria Teresa Landi
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 865.
DOI: https://doi.org/10.1158/1538-7445.AM2021-865
Published: 01 July 2021
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Abstract 211: Integrative mutational signature portal (mSigPortal) for cancer genomic study

Tongwu Zhang, Jian Sang, Phyllip Cho, Kevin Jiang, Maria Teresa Landi
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 211.
DOI: https://doi.org/10.1158/1538-7445.AM2021-211
Published: 01 July 2021
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Assessing Lung Cancer Absolute Risk Trajectory Based on a Polygenic Risk Model

Rayjean J. Hung, Matthew T. Warkentin, Yonathan Brhane, Nilanjan Chatterjee, David C. Christiani, Maria Teresa Landi, Neil E. Caporaso, Geoffrey Liu, Mattias Johansson, Demetrius Albanes, Loic Le Marchand, Adonina Tardon, Gad Rennert, Stig E. Bojesen, Chu Chen, John K. Field, Lambertus A. Kiemeney, Philip Lazarus, Shanbeth Zienolddiny, Stephen Lam, Angeline S. Andrew, Susanne M. Arnold, Melinda C. Aldrich, Heike Bickeböller, Angela Risch, Matthew B. Schabath, James D. McKay, Paul Brennan, Christopher I. Amos
Journal: Cancer Research
Cancer Res (2021) 81 (6): 1607–1615.
DOI: https://doi.org/10.1158/0008-5472.CAN-20-1237
Published: 15 March 2021
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Includes: Supplementary data
Journal Articles

Abstract 1601: Genetic and epigenetic intratumor heterogeneity of lung adenocarcinoma

Wei Zhao, Xing Hua, Tongwu Zhang, Dario Consonni, Angela Cecilia Pesatori, Jianxin Shi, Maria Teresa Landi
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 1601.
DOI: https://doi.org/10.1158/1538-7445.AM2019-1601
Published: 01 July 2019
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Journal Articles

Abstract SY26-02: Sherlock-Lung: Tracing lung cancer mutational processes in never smokers

Maria Teresa Landi, Tongwu Zhang, Montserrat Garcia-Closas, Yohan Bossé, Jianxin Shi, Bin Zhu, Qing Lan, Nathaniel Rothman, Jiyeon Choi, Neil E. Caporaso, Wei Zhao, Chongyi Chen, Eytan Ruppin, Jennifer Rosenbaum, Dmitry Gordenin, Sai Yendamuri, Chris Amos, Paul Brennan, David C. Christiani, Geoff Liu, Bonnie Gould Rothberg, Matthew Schabath, Han Liang, Ludmil Alexandrov, David Wedge, Stephen Chanock
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): SY26-02.
DOI: https://doi.org/10.1158/1538-7445.AM2019-SY26-02
Published: 01 July 2019
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Abstract 1187: Comparison of intra-tumor heterogeneity and clonal evolution across lung cancer subtypes by multi-region whole genome sequencing

Tongwu Zhang, Joshua Sampson, Pier Alberto Bertazzi, Angela Pesatori, Dario Consonni, Bin Zhu, Belynda Hicks, Xing Hua, Jianxin Shi, Kevin Brown, Stephen Chanock, Maria Teresa Landi
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 1187.
DOI: https://doi.org/10.1158/1538-7445.AM2018-1187
Published: 01 July 2018
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Abstract 228: Association analysis across different populations identifies 26 new cutaneous melanoma risk loci

Cristina Pellegrini, Matthew Law, Mark Iles, Mitch Machiela, Alex Stratigos, Tongwu Zhang, Kevin Brown, Julia Newton-Bishop, Nick Hayward, Nick Martin, Alisa Goldstein, Rose Yang, Stephen Chanock, Florence Demenais, Susana Puig, Eduardo Nagore, Jianxin Shi, Tim Bishop, Stuart McGregor, Maria Teresa Landi, GenoMEL Consortium, MelaNostrum Consortium
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 228.
DOI: https://doi.org/10.1158/1538-7445.AM2018-228
Published: 01 July 2018
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Abstract 2185: Multiple region whole-genome sequencing reveals intratumor heterogeneity and branching clonal architecture of non-clear-cell renal cell carcinoma

Bin Zhu*, Luana Poeta*, Manuela Costantini*, Tongwu Zhang*, Steno Sentinelli, Jianxin Shi, Kevin Brown, Xing Hua, Meredith Yeager, Mingyi Wang, Belynda Hicks, Stephen Chanock*, Michele Gallucci*, Vito Fazio*, Maria Teresa Landi*
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 2185.
DOI: https://doi.org/10.1158/1538-7445.AM2018-2185
Published: 01 July 2018
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Abstract 2248: Common TDP1 polymorphisms in relation to survival among small cell lung cancer patients in a multicenter study from the International Lung Cancer Consortium

Pawadee Lohavanichbutr, Lori C. Sakoda, Christopher I. Amos, Susanne M. Arnold, David C. Christiani, Michael P. Davies, John K. Field, Eric B. Haura, Rayjean J. Hung, Takashi Kohno, Maria Teresa Landi, Geoffrey Liu, Yi Liu, Michael W. Marcus, Grainne M. O'Kane, Matthew B. Schabath, Kouya Shiraishi, Stacey A. Slone, Adonina Tardón, Ping Yang, Kazushi Yoshida, Ruyang Zhang, Xuchen Zong, Noel S. Weiss, Chu Chen
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 2248.
DOI: https://doi.org/10.1158/1538-7445.AM2017-2248
Published: 01 July 2017
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Abstract 2292: Lung function and lung cancer risk: a Mendelian randomization study of UK Biobank cohort and the International Lung Cancer Consortium

Linda Kachuri, Mattias Johansson, Paul Brennan, Phillip Haycock, Geoffrey Liu, Maria Teresa Landi, David C. Christiani, Neil E. Caporaso, Xifeng Wu, Melinda C. Aldrich, Demetrius Albanes, Adonina Tardón, Gad Rennert, Chu Chen, Gary E. Goodman, Jennifer A. Doherty, Heike Bickeböller, Dawn Teare, Lambertus A. Kiemeney, Stig E. Bojesen, John K. Field, Aage Haugen, Stephen Lam, Loic Le Marchand, Matthew B. Schabath, Angeline S. Andrew, Jonas Manjer, Philip Lazarus, Susanne M. Arnold, Valérie Gaborieau, Richard Martin, Caroline Relton, George Davey Smith, Christopher I. Amos, James D. McKay, Rayjean J. Hung
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 2292.
DOI: https://doi.org/10.1158/1538-7445.AM2017-2292
Published: 01 July 2017
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Journal Articles

Novel Association of Genetic Markers Affecting CYP2A6 Activity and Lung Cancer Risk

Yesha M. Patel, Sunghim L. Park, Younghun Han, Lynne R. Wilkens, Heike Bickeböller, Albert Rosenberger, Neil Caporaso, Maria Teresa Landi, Irene Brüske, Angela Risch, Yongyue Wei, David C. Christiani, Paul Brennan, Richard Houlston, James McKay, John McLaughlin, Rayjean Hung, Sharon Murphy, Daniel O. Stram, Christopher Amos, Loïc Le Marchand
Journal: Cancer Research
Cancer Res (2016) 76 (19): 5768–5776.
DOI: https://doi.org/10.1158/0008-5472.CAN-16-0446
Published: 02 October 2016
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Includes: Supplementary data
Journal Articles

Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations

Gordon Fehringer, Peter Kraft, Paul D. Pharoah, Rosalind A. Eeles, Nilanjan Chatterjee, Fredrick R. Schumacher, Joellen M. Schildkraut, Sara Lindström, Paul Brennan, Heike Bickeböller, Richard S. Houlston, Maria Teresa Landi, Neil Caporaso, Angela Risch, Ali Amin Al Olama, Sonja I. Berndt, Edward L. Giovannucci, Henrik Grönberg, Zsofia Kote-Jarai, Jing Ma, Kenneth Muir, Meir J. Stampfer, Victoria L. Stevens, Fredrik Wiklund, Walter C. Willett, Ellen L. Goode, Jennifer B. Permuth, Harvey A. Risch, Brett M. Reid, Stephane Bezieau, Hermann Brenner, Andrew T. Chan, Jenny Chang-Claude, Thomas J. Hudson, Jonathan K. Kocarnik, Polly A. Newcomb, Robert E. Schoen, Martha L. Slattery, Emily White, Muriel A. Adank, Habibul Ahsan, Kristiina Aittomäki, Laura Baglietto, Carl Blomquist, Federico Canzian, Kamila Czene, Isabel dos-Santos-Silva, A. Heather Eliassen, Jonine D. Figueroa, Dieter Flesch-Janys, Olivia Fletcher, Montserrat Garcia-Closas, Mia M. Gaudet, Nichola Johnson, Per Hall, Aditi Hazra, Rebecca Hein, Albert Hofman, John L. Hopper, Astrid Irwanto, Mattias Johansson, Rudolf Kaaks, Muhammad G. Kibriya, Peter Lichtner, Jianjun Liu, Eiliv Lund, Enes Makalic, Alfons Meindl, Bertram Müller-Myhsok, Taru A. Muranen, Heli Nevanlinna, Petra H. Peeters, Julian Peto, Ross L. Prentice, Nazneen Rahman, Maria Jose Sanchez, Daniel F. Schmidt, Rita K. Schmutzler, Melissa C. Southey, Rulla Tamimi, Ruth C. Travis, Clare Turnbull, Andre G. Uitterlinden, Zhaoming Wang, Alice S. Whittemore, Xiaohong R. Yang, Wei Zheng, Daniel D. Buchanan, Graham Casey, David V. Conti, Christopher K. Edlund, Steven Gallinger, Robert W. Haile, Mark Jenkins, Loïc Le Marchand, Li Li, Noralene M. Lindor, Stephanie L. Schmit, Stephen N. Thibodeau, Michael O. Woods, Thorunn Rafnar, Julius Gudmundsson, Simon N. Stacey, Kari Stefansson, Patrick Sulem, Y. Ann Chen, Jonathan P. Tyrer, David C. Christiani, Yongyue Wei, Hongbing Shen, Zhibin Hu, Xiao-Ou Shu, Kouya Shiraishi, Atsushi Takahashi, Yohan Bossé, Ma'en Obeidat, David Nickle, Wim Timens, Matthew L. Freedman, Qiyuan Li, Daniela Seminara, Stephen J. Chanock, Jian Gong, Ulrike Peters, Stephen B. Gruber, Christopher I. Amos, Thomas A. Sellers, Douglas F. Easton, David J. Hunter, Christopher A. Haiman, Brian E. Henderson, Rayjean J. Hung
Journal: Cancer Research
Cancer Res (2016) 76 (17): 5103–5114.
DOI: https://doi.org/10.1158/0008-5472.CAN-15-2980
Published: 31 August 2016
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Includes: Supplementary data
Journal Articles

Abstract 2569: A genome wide association study of lung cancer identifies 11 novel susceptibility loci

James Dowling Mckay, Yafang Li, Younghun Han, Xiangjun Xioa, John Field, Xuchen Zong, Heike Bickeböller, David C. Christiani, Paul Brennan, Maria-Teresa Landi, Rayjean Hung, Christopher I. Amos, on behalf of the OncoArray Lung Cancer Group
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 2569.
DOI: https://doi.org/10.1158/1538-7445.AM2016-2569
Published: 15 July 2016
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Abstract 817: Mendelian randomization and mediation analysis of 5p15.33, telomere length and lung cancer risk

Linda Kachuri, George Davey Smith, Geoffrey Liu, Maria Teresa Landi, David C. Christiani, Neil E. Caporaso, James D. McKay, Xifeng Wu, Melinda C. Aldrich, Gad Rennert, Dawn Teare, Chu Chen, Gary E. Goodman, Jennifer A. Doherty, John K. Field, Lambertus A. Kiemeney, Adonina Tardón, Aage Haugen, Stephen Lam, Loic Le Marchand, Matthew B. Schabath, Angeline S. Andrew, Mattias Johansson, Jonas Manjer, Philip Lazarus, Susanne Arnold, Gordon Fehringer, Xuchen Zong, Paul Brennan, Stig E. Bojesen, Christopher I. Amos, Rayjean J. Hung
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 817.
DOI: https://doi.org/10.1158/1538-7445.AM2016-817
Published: 15 July 2016
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Abstract 4597: A novel variant in DNA repair gene GTF2H4 is associated with lung cancer risk: A reanalysis of GWAS datasets from the TRICL consortium

Qingyi Wei, Hongliang Liu, Zhensheng Liu, Christopher I. Amos, Jennifer A. Doherty, Heike Bickeboller, Rayjean J. Hung, Paul Brennan, Richard Houlston, Maria Teresa Landi, Neil E. Caporaso, David Christiani
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 4597.
DOI: https://doi.org/10.1158/1538-7445.AM2015-4597
Published: 01 August 2015
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Abstract 287: Characterizing the genetic basis of methylome diversity in histologically normal human lung tissue

Jianxin Shi, Crystal Marconett, Jubao Duan, Paula Hyland, Peng Li, Zhaoming Wang, William Wheeler, Mihaela Campan, Jing Huang, Weiyin Zhou, Tim Triche, Laufey Amundadottir, Amy Hutchinson, Po-Han Chen, Beiyun Zhou, Brian Chung, Pier Alberto Bertazzi, Andrew W. Bergen, Mathew Freedman, Diane Lee, Kim Siegmund, Andrew Clay Warner, Ben Berman, Angela C. Pesatori, Zea Borok, Dario Consonni, Nilanjan Chatterjee, Margaret Tucker, Neil Caporaso, Stephen J. Chanock, Ite A. Laird-Offringa, Maria Teresa Landi
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 287.
DOI: https://doi.org/10.1158/1538-7445.AM2014-287
Published: 01 October 2014
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Abstract 286: Epigenome-wide association study of normal lung tissues identifies hypomethylation of multiple CpG sites associated with cigarette smoking

Wen-Qing Li, Jianxin Shi, William Wheeler, Neil Caporaso, Ite Laird-Offspringa, Maria Teresa Landi
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 286.
DOI: https://doi.org/10.1158/1538-7445.AM2014-286
Published: 01 October 2014
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Abstract 2157: Causal effects of delaying smoking initiation on subsequent lung cancer risk

Orestis A. Panagiotou, Fangyi Gu, Carolyn Reyes-Guzman, Maria-Teresa Landi, Michele Bloch, Neil E. Caporaso, Sholom Wacholder
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 2157.
DOI: https://doi.org/10.1158/1538-7445.AM2014-2157
Published: 01 October 2014
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Abstract 2251: nrf2-keap1 axis molecular profile in small cell lung cancer cell lines

Lucia Anna Muscarella, Annamaria la Torre, Angelo Sparaneo, Orazio Palumbo, Clelia Tiziana Storlazzi, Teresa Balsamo, Domenico Trombetta, Fabio Pellegrini, Raffaela Barbano, Barbara Pasculli, Paolo Graziano, Montse Sanchez-cespedes, Maria Teresa Landi, Paola Parrella, Vito Michele Fazio
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 2251.
DOI: https://doi.org/10.1158/1538-7445.AM2014-2251
Published: 01 October 2014
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Abstract 942: Imputation from The 1000 Genomes Project identifies rare large effect variants of BRCA2-K3326X and CHEK2-I157T as risk factors for lung cancer; a study from the TRICL consortium

Maria Teresa Landi, Yufei Wang, James D. Mckay, Thorunn Rafnar, Zhaoming Wang, Maria Timofeeva, Peter Broderick, Kari Stefansson, Angela Risch, Stephen J. Chanock, David C. Christiani, Rayjean J. Hung, Paul Brennan, Richard S. Houlston, Christopher I. Amos
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 942.
DOI: https://doi.org/10.1158/1538-7445.AM2014-942
Published: 01 October 2014
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