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Journal Articles

Abstract 3005: Low-density lipoprotein receptor-related protein 1B (LRP1B) depletion promotes tumorigenicity by modulating fibroblasts in the tumor microenvironment in esophageal squamous cell carcinoma

KaiYan Xu, Josephine Mun-yee KO, Valen Zhuo you Yu, Maria Li LUNG
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 3005.
https://doi.org/10.1158/1538-7445.AM2024-3005
Published: 22 March 2024
View article titled, Abstract 3005: <em>Low-density lipoprotein receptor-related protein 1B</em> (<em>LRP1B</em>) depletion promotes tumorigenicity by modulating fibroblasts in the tumor microenvironment in esophageal squamous cell carcinoma
Journal Articles

Abstract 2611: p63 constrains cancer cell transposable element expressions and viral mimicry response to sustain esophageal cancer development and indicates therapeutic vulnerability

Valen Zhuoyou Yu, Shan Shan So, Bryan Chee-Chad Lung, Carissa Wing-Yan Wong, Ian Yu-Hong Wong, Claudia Lai-Yin Wong, Desmond Kwan-Kit Chan, Fion Siu-Yin Chan, Betty Tsz-Ting Law, Ka-On Lam, Anthony Wing-Ip Lo, Josephine Mum-Yee Ko, Wei Dai, Alfred King-Yin Lam, Dora Lai-Wan Kwong, Simon Law, Maria Li Lung
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 2611.
https://doi.org/10.1158/1538-7445.AM2023-2611
Published: 04 April 2023
View article titled, Abstract 2611: p63 constrains cancer cell transposable element expressions and viral mimicry response to sustain esophageal cancer development and indicates therapeutic vulnerability
Journal Articles

Abstract 6705: Molecular detection of circulating cancer cells with cancer stem cell or mesenchymal characteristics in esophageal squamous cell carcinoma

Zhen Tan, Josephine Mun-Yee Ko, Valen Zhuoyou Yu, Hoi Yan Ng, Simon Law, Maria Li Lung
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 6705.
https://doi.org/10.1158/1538-7445.AM2023-6705
Published: 04 April 2023
View article titled, Abstract 6705: Molecular detection of circulating cancer cells with cancer stem cell or mesenchymal characteristics in esophageal squamous cell carcinoma
Journal Articles

Abstract 1359: Characterisation of heterogeneity of esophageal squamous cell carcinoma ecosystem by single-cell transcriptomics analysis

Carissa Wing-Yan Wong, Josephine Mun-Yee Ko, Hoi Yan Ng, Valen Zhuoyou Yu, Simon Law, Maria Li Lung
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 1359.
https://doi.org/10.1158/1538-7445.AM2023-1359
Published: 04 April 2023
View article titled, Abstract 1359: Characterisation of heterogeneity of esophageal squamous cell carcinoma ecosystem by single-cell transcriptomics analysis
Journal Articles

Abstract 4734: Nasopharyngeal carcinoma molecular subgroups for somatic copy number alterations (SCNAs)

Wei Dai, Dittman Lai-Shun Chung, Larry Ka-Yue Chow, Merrin Man-Long Leong, Candy King-Chi Chan, Josephine Mun-Yee Ko, Maria Li Lung
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 4734.
https://doi.org/10.1158/1538-7445.AM2020-4734
Published: 15 August 2020
View article titled, Abstract 4734: Nasopharyngeal carcinoma molecular subgroups for somatic copy number alterations (SCNAs)
Journal Articles

Abstract 3665: A unique CpG-island methylator phenotype associated with Epstein-Barr virus (EBV) and CCCTC-binding factor (CTCF) in nasopharyngeal carcinoma

Ka Yue Larry Chow, Wei Dai, Maria Li Lung
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 3665.
https://doi.org/10.1158/1538-7445.AM2020-3665
Published: 15 August 2020
View article titled, Abstract 3665: A unique CpG-island methylator phenotype associated with Epstein-Barr virus (EBV) and CCCTC-binding factor (CTCF) in nasopharyngeal carcinoma
Journal Articles

Epstein–Barr Virus miRNA BART2-5p Promotes Metastasis of Nasopharyngeal Carcinoma by Suppressing RND3

Chen Jiang, Lei Li, Yan-Qun Xiang, Maria Li Lung, Tingting Zeng, Jiabin Lu, Sai Wah Tsao, Mu-Sheng Zeng, Jing-Ping Yun, Dora L.W. Kwong, Xin-Yuan Guan
Journal: Cancer Research
Cancer Res (2020) 80 (10): 1957–1969.
https://doi.org/10.1158/0008-5472.CAN-19-0334
Published: 15 May 2020
View article titled, Epstein–Barr Virus miRNA BART2-5p Promotes Metastasis of Nasopharyngeal Carcinoma by Suppressing RND3
Open the PDF for Epstein–Barr Virus miRNA BART2-5p Promotes Metastasis of Nasopharyngeal Carcinoma by Suppressing RND3 in another window
Includes: Supplementary data
Journal Articles

Abstract 3465: FANCD2 depletion suppresses tumor growth in esophageal squamous cell carcinoma

Chan Lei, Zhuoyou Yu, Lvwen Ning, Mun-Yee Ko, Lidong Wang, Maria Li Lung
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 3465.
https://doi.org/10.1158/1538-7445.AM2019-3465
Published: 01 July 2019
View article titled, Abstract 3465: FANCD2 depletion suppresses tumor growth in esophageal squamous cell carcinoma
Journal Articles

Abstract 5192: EBV-associated histone modifications regulate DNA damage repair pathway and associate with cisplatin resistance in nasopharyngeal epithelial malignancy

Merrin Man Long Leong, Arthur Kwok Leung Cheung, Wei Dai, Sai Wah Tsao, Maria Li Lung
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 5192.
https://doi.org/10.1158/1538-7445.AM2019-5192
Published: 01 July 2019
View article titled, Abstract 5192: EBV-associated histone modifications regulate DNA damage repair pathway and associate with cisplatin resistance in nasopharyngeal epithelial malignancy
Journal Articles

Abstract 56: Establishment and characterization of new tumor xenografts and cancer cell lines from EBV positive nasopharyngeal carcinoma

Weitao Lin, Yim Ling Yip, Lin Jia, Wen Deng, Kwok Wai Lo, Chin Man Tsang, Maria Li Lung, George Sai Tsao
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 56.
https://doi.org/10.1158/1538-7445.AM2019-56
Published: 01 July 2019
View article titled, Abstract 56: Establishment and characterization of new tumor xenografts and cancer cell lines from EBV positive nasopharyngeal carcinoma
Journal Articles

Abstract 3419: Genomic characterization of mutation hotspots related to chemotherapy responses in esophageal squamous-cell carcinoma with archived formalin-fixed paraffin-embedded tissues

Chen Guo, Josephine Ko, Wei Dai, Lihua Tao, Simon Law, Anthony Wing Ip Lo, Maria Li Lung
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 3419.
https://doi.org/10.1158/1538-7445.AM2018-3419
Published: 01 July 2018
View article titled, Abstract 3419: Genomic characterization of mutation hotspots related to chemotherapy responses in esophageal squamous-cell carcinoma with archived formalin-fixed paraffin-embedded tissues
Journal Articles

Abstract 1357: Functional characterization of FANCD2 in esophageal squamous cell carcinoma

Lisa Chan Lei, Valen Zhuoyou Yu, Lvwen Ning, Josephine Mun-Yee Ko, Li Dong Wang, Maria Li Lung
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 1357.
https://doi.org/10.1158/1538-7445.AM2018-1357
Published: 01 July 2018
View article titled, Abstract 1357: Functional characterization of FANCD2 in esophageal squamous cell carcinoma
Journal Articles

Abstract 327: Functional characterization of RAD50 germline deleterious variants identified from deep targeted sequencing study of familial esophageal squamous cell carcinoma

Shiu Yeung Lam, Lvwen Ning, Hoi Yan Ng, Maria Li Lung, Josephine Mun-Yee Ko
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 327.
https://doi.org/10.1158/1538-7445.AM2018-327
Published: 01 July 2018
View article titled, Abstract 327: Functional characterization of <em>RAD50</em> germline deleterious variants identified from deep targeted sequencing study of familial esophageal squamous cell carcinoma
Journal Articles

Abstract 439: Elucidation of genetic susceptibility in nasopharyngeal carcinoma (NPC) by next-generation sequencing

Wei Dai, Josephine Mun Yee Ko, Bianca Hoi Yan Ng, Hong Zheng, Maria Li Lung
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 439.
https://doi.org/10.1158/1538-7445.AM2018-439
Published: 01 July 2018
View article titled, Abstract 439: Elucidation of genetic susceptibility in nasopharyngeal carcinoma (NPC) by next-generation sequencing
Journal Articles

Abstract 423: Investigating the germline deleterious rare variants for genetic susceptibility of esophagus squamous cell carcinomas by target sequencing

Lvwen Ning, Josephine Mun Yee Ko, Lisa Chan Lei, Li Dong Wang, Maria Li Lung
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 423.
https://doi.org/10.1158/1538-7445.AM2018-423
Published: 01 July 2018
View article titled, Abstract 423: Investigating the germline deleterious rare variants for genetic susceptibility of esophagus squamous cell carcinomas by target sequencing
Journal Articles

Abstract 5521: Functional characterization of a candidate tumor suppressor gene, Mirror image polydactyly 1, in nasopharyngeal carcinoma

Merrin Man Long Leong, Arthur Kwok Leung Cheung, Tommy Chin Tung Kwok, Maria Li Lung
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 5521.
https://doi.org/10.1158/1538-7445.AM2018-5521
Published: 01 July 2018
View article titled, Abstract 5521: Functional characterization of a candidate tumor suppressor gene, <em>Mirror image polydactyly 1</em>, in nasopharyngeal carcinoma
Journal Articles

Abstract 1158: Differential expression and functional impact of the alternatively spliced transcripts of Extracellular matrix protein 1 in esophageal squamous cell carcinoma

Valen Zhuoyou YU, Josephine Mun-Yee Ko, Simon Law, Li Dong Wang, Maria Li Lung
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 1158.
https://doi.org/10.1158/1538-7445.AM2016-1158
Published: 15 July 2016
View article titled, Abstract 1158: Differential expression and functional impact of the alternatively spliced transcripts of Extracellular matrix protein 1 in esophageal squamous cell carcinoma
Journal Articles

Abstract 5234: Rare deleterious germline mutations of candidate genes associated with risk of familial esophageal squamous cell carcinoma (ESCC) by targeted sequencing

Josephine Mun Yee Ko, Lu wen Ni, Sheyne, Sta Ana Choi, Lisa Chan Lei, Li Dong Wang, Maria Li Lung
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 5234.
https://doi.org/10.1158/1538-7445.AM2016-5234
Published: 15 July 2016
View article titled, Abstract 5234: Rare deleterious germline mutations of candidate genes associated with risk of familial esophageal squamous cell carcinoma (ESCC) by targeted sequencing
Journal Articles

Abstract 4773: Aberrant methylation at chromosome 6p as novel biomarkers for diagnosis and prognosis of nasopharyngeal carcinoma

Wei Dai, Arthur Kwok Leung Cheung, Josephine Mun Yee Ko, Hong Zheng, Yue Cheng, Roger Kai Cheong Ngan, Wai Tong Ng, Anne Wing Mui Lee, Chun Chung Yau, Victor Ho Fu Lee, Maria Li Lung
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 4773.
https://doi.org/10.1158/1538-7445.AM2015-4773
Published: 01 August 2015
View article titled, Abstract 4773: Aberrant methylation at chromosome 6p as novel biomarkers for diagnosis and prognosis of nasopharyngeal carcinoma
Journal Articles

Abstract 1921: Unraveling the genetic basis of nasopharyngeal carcinoma using next-generation sequencing approaches

Hong Zheng, Wei Dai, Clara Tang, Arthur Cheung, Josephine Ko, Pak Sham, Maria Li Lung
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 1921.
https://doi.org/10.1158/1538-7445.AM2015-1921
Published: 01 August 2015
View article titled, Abstract 1921: Unraveling the genetic basis of nasopharyngeal carcinoma using next-generation sequencing approaches