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Margaret E. McLaughlin
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Journal Articles

A Proof of Concept for Biomarker-Guided Targeted Therapy against Ovarian Cancer Based on Patient-Derived Tumor Xenografts

Adam C. Palmer, Deborah Plana, Hui Gao, Joshua M. Korn, Guizhi Yang, John Green, Xiamei Zhang, Roberto Velazquez, Margaret E. McLaughlin, David A. Ruddy, Colleen Kowal, Julie Muszynski, Caroline Bullock, Stacy Rivera, Daniel P. Rakiec, GiNell Elliott, Paul Fordjour, Ronald Meyer, Alice Loo, Esther Kurth, Jeffrey A. Engelman, Hans Bitter, William R. Sellers, Juliet A. Williams, Peter K. Sorger
Journal: Cancer Research
Cancer Res (2020) 80 (19): 4278–4287.
https://doi.org/10.1158/0008-5472.CAN-19-3850
Published: 02 October 2020
View articletitled, A Proof of Concept for Biomarker-Guided Targeted Therapy against Ovarian Cancer Based on Patient-Derived Tumor Xenografts
Open the PDF for A Proof of Concept for Biomarker-Guided Targeted Therapy against Ovarian Cancer Based on Patient-Derived Tumor Xenografts in another window
Includes: Supplementary data
Journal Articles

Abstract 2140: Dual Wnt and EGFR-MAPK dependency of BRAFV600E-mutant colorectal cancer

Youzhen Wang, Michael Palmer, Savina Jaeger, Linda Bagdasarian, Shumei Qiu, Steve Woolfenden, Ronald Meyer, Guizhi Yang, John Green, Shifeng Pan, Jun Liu, Hui Gao, Z. Alexander Cao, Andrea Myers, Margaret E. McLaughlin
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 2140.
https://doi.org/10.1158/1538-7445.AM2015-2140
Published: 01 August 2015
View articletitled, Abstract 2140: Dual Wnt and EGFR-MAPK dependency of BRAFV600E-mutant colorectal cancer
Journal Articles

Endogenous Two-Photon Fluorescence Imaging Elucidates Metabolic Changes Related to Enhanced Glycolysis and Glutamine Consumption in Precancerous Epithelial Tissues

Antonio Varone, Joanna Xylas, Kyle P. Quinn, Dimitra Pouli, Gautham Sridharan, Margaret E. McLaughlin-Drubin, Carlo Alonzo, Kyongbum Lee, Karl Münger, Irene Georgakoudi
Journal: Cancer Research
Cancer Res (2014) 74 (11): 3067–3075.
https://doi.org/10.1158/0008-5472.CAN-13-2713
Published: 29 May 2014
View articletitled, Endogenous Two-Photon Fluorescence Imaging Elucidates Metabolic Changes Related to Enhanced Glycolysis and Glutamine Consumption in Precancerous Epithelial Tissues
Open the PDF for Endogenous Two-Photon Fluorescence Imaging Elucidates Metabolic Changes Related to Enhanced Glycolysis and Glutamine Consumption in Precancerous Epithelial Tissues in another window
Includes: Multimedia, Supplementary data
Journal Articles

Delocalization of the Microtubule Motor Dynein from Mitotic Spindles by the Human Papillomavirus E7 Oncoprotein Is Not Sufficient for Induction of Multipolar Mitoses

Christine L. Nguyen, Margaret E. McLaughlin-Drubin, Karl Münger
Journal: Cancer Research
Cancer Res (2008) 68 (21): 8715–8722.
https://doi.org/10.1158/0008-5472.CAN-08-1303
Published: 30 October 2008
View articletitled, Delocalization of the Microtubule Motor Dynein from Mitotic Spindles by the Human Papillomavirus E7 Oncoprotein Is Not Sufficient for Induction of Multipolar Mitoses
Open the PDF for Delocalization of the Microtubule Motor Dynein from Mitotic Spindles by the Human Papillomavirus E7 Oncoprotein Is Not Sufficient for Induction of Multipolar Mitoses in another window
Journal Articles

ROS Fusion Tyrosine Kinase Activates a SH2 Domain–Containing Phosphatase-2/Phosphatidylinositol 3-Kinase/Mammalian Target of Rapamycin Signaling Axis to Form Glioblastoma in Mice

Al Charest, Erik W. Wilker, Margaret E. McLaughlin, Keara Lane, Ram Gowda, Shanie Coven, Kevin McMahon, Steven Kovach, Yun Feng, Michael B. Yaffe, Tyler Jacks, David Housman
Journal: Cancer Research
Cancer Res (2006) 66 (15): 7473–7481.
https://doi.org/10.1158/0008-5472.CAN-06-1193
Published: 02 August 2006
View articletitled, ROS Fusion Tyrosine Kinase Activates a SH2 Domain–Containing Phosphatase-2/Phosphatidylinositol 3-Kinase/Mammalian Target of Rapamycin Signaling Axis to Form Glioblastoma in Mice
Open the PDF for ROS Fusion Tyrosine Kinase Activates a SH2 Domain–Containing Phosphatase-2/Phosphatidylinositol 3-Kinase/Mammalian Target of Rapamycin Signaling Axis to Form Glioblastoma in Mice in another window
Includes: Supplementary data
Journal Articles

The role of the HPV16 E7/E2F6 interaction in viral oncogenesis

Margaret E. Mclaughlin-Drubin, Kyung-Won Huh, Karl Munger
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 1040.
Published: 15 April 2006
View articletitled, The role of the HPV16 E7/E2F6 interaction in viral oncogenesis
Journal Articles

Comparative Pathology of Nerve Sheath Tumors in Mouse Models and Humans

Anat O. Stemmer-Rachamimov, David N. Louis, Gunnlaugur P. Nielsen, Cristina R. Antonescu, Alexander D. Borowsky, Roderick T. Bronson, Dennis K. Burns, Pascale Cervera, Margaret E. McLaughlin, Guido Reifenberger, Michael C. Schmale, Mia MacCollin, Richard C. Chao, Karen Cichowski, Michel Kalamarides, Shanta M. Messerli, Andrea I. McClatchey, Michiko Niwa-Kawakita, Nancy Ratner, Karlyne M. Reilly, Yuan Zhu, Marco Giovannini
Journal: Cancer Research
Cancer Res (2004) 64 (10): 3718–3724.
https://doi.org/10.1158/0008-5472.CAN-03-4079
Published: 17 May 2004
View articletitled, Comparative Pathology of Nerve Sheath Tumors in Mouse Models and Humans
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Journal Articles

Gene Expression-based Classification of Malignant Gliomas Correlates Better with Survival than Histological Classification

Catherine L. Nutt, D. R. Mani, Rebecca A. Betensky, Pablo Tamayo, J. Gregory Cairncross, Christine Ladd, Ute Pohl, Christian Hartmann, Margaret E. McLaughlin, Tracy T. Batchelor, Peter M. Black, Andreas von Deimling, Scott L. Pomeroy, Todd R. Golub, David N. Louis
Journal: Cancer Research
Cancer Res (2003) 63 (7): 1602–1607.
Published: 01 April 2003
View articletitled, Gene Expression-based Classification of Malignant Gliomas Correlates Better with Survival than Histological Classification
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Journal Articles

Progesterone Receptor Expression in Neurofibromas

Margaret E. McLaughlin, Tyler Jacks
Journal: Cancer Research
Cancer Res (2003) 63 (4): 752–755.
Published: 15 February 2003
View articletitled, Progesterone Receptor Expression in Neurofibromas
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