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Journal Articles

Abstract 3145: Mechanisms of resistance to FGFR-targeted therapy in bladder cancer

Geoffrey A. Pettitt, Helen R. McPherson, Carolyn D. Hurst, Julie E. Burns, Olivia A. Alder, Matthew C. Dunning, Margaret A. Knowles

Cancer Res (2017) 77 (13_Supplement): 3145.

DOI: https://doi.org/10.1158/1538-7445.AM2017-3145

Published: 01 July 2017

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Journal Articles

Abstract LB-323: The genomic landscape of non-muscle-invasive bladder cancer: implications for molecular classification and treatment

Carolyn D. Hurst, Olivia Alder, Fiona M. Platt, Alastair Droop, Lucy F. Stead, Julie E. Burns, George J. Burghel, Sunjay Jain, Leszek J. Klimczak, Helen Lindsay, Jo-An Roulson, Claire F. Taylor, Helene Thygesen, Angus J. Cameron, Anne J. Ridley, Helene R. Mott, Dmitry A. Gordenin, Margaret A. Knowles

Cancer Res (2016) 76 (14_Supplement): LB-323.

DOI: https://doi.org/10.1158/1538-7445.AM2016-LB-323

Published: 15 July 2016

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Journal Articles

Abstract 2240: TERT promoter mutations are highly prevalent in bladder cancer and represent a potential new urinary biomarker

Carolyn D. Hurst, Fiona M. Platt, Margaret A. Knowles

Cancer Res (2014) 74 (19_Supplement): 2240.

DOI: https://doi.org/10.1158/1538-7445.AM2014-2240

Published: 01 October 2014

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Journal Articles

Abstract 821: Subgroups of urothelial carcinoma of the bladder defined by genomic analysis.

Carolyn D. Hurst, Fiona M. Platt, Claire F. Taylor, Margaret A. Knowles

Cancer Res (2013) 73 (8_Supplement): 821.

DOI: https://doi.org/10.1158/1538-7445.AM2013-821

Published: 15 April 2013

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Journal Articles

Abstract 5310: Activation of FGFR3 by genomic fusion in urothelial carcinoma of the bladder.

Sarah V. Williams, Carolyn D. Hurst, Margaret A. Knowles

Cancer Res (2013) 73 (8_Supplement): 5310.

DOI: https://doi.org/10.1158/1538-7445.AM2013-5310

Published: 15 April 2013

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Journal Articles

Imatinib Radiosensitizes Bladder Cancer by Targeting Homologous Recombination

Boling Qiao, Martin Kerr, Blaz Groselj, Mark T.W. Teo, Margaret A. Knowles, Robert G. Bristow, Roger M. Phillips, Anne E. Kiltie

Cancer Res (2013) 73 (5): 1611–1620.

DOI: https://doi.org/10.1158/0008-5472.CAN-12-1170

Published: 03 March 2013

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Includes: Supplementary data

Journal Articles

Abstract LB-152: PIK3CA mutation spectrum in urothelial carcinoma reflects cell context-dependent signalling and phenotypic outputs

Rebecca L. Ross, Jon M. Askham, Margaret A. Knowles

Cancer Res (2012) 72 (8_Supplement): LB-152.

DOI: https://doi.org/10.1158/1538-7445.AM2012-LB-152

Published: 15 April 2012

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Journal Articles

MRE11 Expression Is Predictive of Cause-Specific Survival following Radical Radiotherapy for Muscle-Invasive Bladder Cancer

Ananya Choudhury, Louisa D. Nelson, Mark T.W. Teo, Sameer Chilka, Selina Bhattarai, Colin F. Johnston, Faye Elliott, Johanna Lowery, Claire F. Taylor, Michael Churchman, Johanne Bentley, Margaret A. Knowles, Patricia Harnden, Robert G. Bristow, D. Timothy Bishop, Anne E. Kiltie

Cancer Res (2010) 70 (18): 7017–7026.

DOI: https://doi.org/10.1158/0008-5472.CAN-10-1202

Published: 14 September 2010

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Includes: Supplementary data

Journal Articles

Distinct MicroRNA Alterations Characterize High- and Low-Grade Bladder Cancer

James W.F. Catto, Saiful Miah, Helen C. Owen, Helen Bryant, Katie Myers, Ewa Dudziec, Stéphane Larré, Marta Milo, Ishtiaq Rehman, Derek J. Rosario, Erica Di Martino, Margaret A. Knowles, Mark Meuth, Adrian L. Harris, Freddie C. Hamdy

Cancer Res (2009) 69 (21): 8472–8481.

DOI: https://doi.org/10.1158/0008-5472.CAN-09-0744

Published: 28 October 2009

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Includes: Supplementary data

Journal Articles

Fibroblast Growth Factor Receptor 1 Promotes Proliferation and Survival via Activation of the Mitogen-Activated Protein Kinase Pathway in Bladder Cancer

Darren C. Tomlinson, Fiona R. Lamont, Steve D. Shnyder, Margaret A. Knowles

Cancer Res (2009) 69 (11): 4613–4620.

DOI: https://doi.org/10.1158/0008-5472.CAN-08-2816

Published: 01 June 2009

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Journal Articles

Bladder tumor derived TSC1 missense mutants show defective control of mTOR signalling

Louis S. Pymar, Fiona M. Platt, Ewan E. Morrison, Margaret A. Knowles

Cancer Res (2006) 66 (8_Supplement): 933.

Published: 15 April 2006

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Journal Articles

expression and functional analysis of Neuregulin1 and its receptors in human bladder cancer

James A. Forster, Alan B. Paul, Margaret A. Knowles

Cancer Res (2006) 66 (8_Supplement): 974.

Published: 15 April 2006

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Journal Articles

Assessment of candidate oncogenes from the 6p22.3 region amplified in bladder cancer

Carolyn D. Hurst, Sarah Williams, Darren Tomlinson, Margaret A. Knowles

Cancer Res (2006) 66 (8_Supplement): 608.

Published: 15 April 2006

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Journal Articles

Alternative Splicing of Fibroblast Growth Factor Receptor 3 Produces a Secreted Isoform That Inhibits Fibroblast Growth Factor–Induced Proliferation and Is Repressed in Urothelial Carcinoma Cell Lines

Darren C. Tomlinson, Corine G. L'Hôte, Wendy Kennedy, Eva Pitt, Margaret A. Knowles

Cancer Res (2005) 65 (22): 10441–10449.

DOI: https://doi.org/10.1158/0008-5472.CAN-05-1718

Published: 15 November 2005

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Journal Articles

Functional characterisation of DBC1, a tumor suppressor gene involved in bladder cancer

Hilda A. Pickett, Eva Pitt, Jari Louhelainen, Margaret A. Knowles

Cancer Res (2005) 65 (9_Supplement): 679.

Published: 01 May 2005

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Journal Articles

Expression and characterization of FGFR3 splice variants in the normal urothelium and urothelial tumors

Darren C. Tomlinson, Wendy Kennedy, Corine G. L’Hote, Eva Pitt, Margaret A. Knowles

Cancer Res (2005) 65 (9_Supplement): 242.

Published: 01 May 2005

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Journal Articles

Uroplakin promoters for tissue-specific adenovirus-mediated suicide gene therapy in bladder cancer

Drew Burdon, Tracy J. Harvey, Margaret A. Knowles, Peter J. Selby, John D. Chester

Cancer Res (2005) 65 (9_Supplement): 791.

Published: 01 May 2005

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Journal Articles

Loss of Heterozygosity Analysis and DNA Copy Number Measurement on 8p in Bladder Cancer Reveals Two Mechanisms of Allelic Loss

Jacqui Adams, Sarah V. Williams, Joanne S. Aveyard, Margaret A. Knowles

Cancer Res (2005) 65 (1): 66–75.

DOI: https://doi.org/10.1158/0008-5472.66.65.1

Published: 21 January 2005

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Journal Articles

The effect of cisplatin adducts on double strand break repair by non-homologous end joining

Christine P. Diggle, Johanne Bentley, Margaret A. Knowles, Anne E. Kiltie

Cancer Res (2004) 64 (7_Supplement): 615.

Published: 01 April 2004

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Journal Articles

Analysis of genomic copy number alterations in bladder cancer by array-based comparative genomic hybridisation

Carolyn D. Hurst, Heike Fiegler, Philippa Carr, Sarah Williams, Nigel P. Carter, Margaret A. Knowles

Cancer Res (2004) 64 (7_Supplement): 652.

Published: 01 April 2004

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NARROW

Abstract 3145: Mechanisms of resistance to FGFR-targeted therapy in bladder cancer

Abstract LB-323: The genomic landscape of non-muscle-invasive bladder cancer: implications for molecular classification and treatment

Abstract 2240: TERT promoter mutations are highly prevalent in bladder cancer and represent a potential new urinary biomarker

Abstract 821: Subgroups of urothelial carcinoma of the bladder defined by genomic analysis.

Abstract 5310: Activation of FGFR3 by genomic fusion in urothelial carcinoma of the bladder.

Imatinib Radiosensitizes Bladder Cancer by Targeting Homologous Recombination

Abstract LB-152: PIK3CA mutation spectrum in urothelial carcinoma reflects cell context-dependent signalling and phenotypic outputs

MRE11 Expression Is Predictive of Cause-Specific Survival following Radical Radiotherapy for Muscle-Invasive Bladder Cancer

Distinct MicroRNA Alterations Characterize High- and Low-Grade Bladder Cancer

Fibroblast Growth Factor Receptor 1 Promotes Proliferation and Survival via Activation of the Mitogen-Activated Protein Kinase Pathway in Bladder Cancer

Bladder tumor derived TSC1 missense mutants show defective control of mTOR signalling

expression and functional analysis of Neuregulin1 and its receptors in human bladder cancer

Assessment of candidate oncogenes from the 6p22.3 region amplified in bladder cancer

Alternative Splicing of Fibroblast Growth Factor Receptor 3 Produces a Secreted Isoform That Inhibits Fibroblast Growth Factor–Induced Proliferation and Is Repressed in Urothelial Carcinoma Cell Lines

Functional characterisation of DBC1, a tumor suppressor gene involved in bladder cancer

Expression and characterization of FGFR3 splice variants in the normal urothelium and urothelial tumors

Uroplakin promoters for tissue-specific adenovirus-mediated suicide gene therapy in bladder cancer

Loss of Heterozygosity Analysis and DNA Copy Number Measurement on 8p in Bladder Cancer Reveals Two Mechanisms of Allelic Loss

The effect of cisplatin adducts on double strand break repair by non-homologous end joining

Analysis of genomic copy number alterations in bladder cancer by array-based comparative genomic hybridisation

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