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Abstract 3424: IL-18 immunotherapy is efficacious against checkpoint-immunotherapy refractory tumors by promoting the maturation of highly proliferative, polyfunctional NK cells

Orr-El Weizman, Ting Zhou, William Damsky, Meaghan McGeary, Marcus W. Bosenberg, Aaron M. Ring

Cancer Res (2020) 80 (16_Supplement): 3424.

DOI: https://doi.org/10.1158/1538-7445.AM2020-3424

Published: 15 August 2020

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Journal Articles

Abstract 2156: IL-18 pathway agonism expands intratumoral PD1+ Tcf1+ stem-like CD8+ cells and their polyfunctional effector progeny to promote anti-tumor immunity

Ting Zhou, Orr-El Weizman, William Damsky, Meaghan McGeary, Marcus W. Bosenberg, Aaron M. Ring

Cancer Res (2020) 80 (16_Supplement): 2156.

DOI: https://doi.org/10.1158/1538-7445.AM2020-2156

Published: 15 August 2020

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Journal Articles

Abstract 4622: The YUMMER.G mouse melanoma model recapitulates the heterogeneous response to immune checkpoint blockade based on patient sex

Julie Y. Ramseier, Alexandra Charos, Koonam Park, William Damsky, Marcus W. Bosenberg

Cancer Res (2019) 79 (13_Supplement): 4622.

DOI: https://doi.org/10.1158/1538-7445.AM2019-4622

Published: 01 July 2019

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Journal Articles

Extracorporeal Photochemotherapy Drives Monocyte-to-Dendritic Cell Maturation to Induce Anticancer Immunity

Alessandra Ventura, Aaron Vassall, Eve Robinson, Renata Filler, Douglas Hanlon, Katrina Meeth, Harib Ezaldein, Michael Girardi, Olga Sobolev, Marcus W. Bosenberg, Richard L. Edelson

Cancer Res (2018) 78 (14): 4045–4058.

DOI: https://doi.org/10.1158/0008-5472.CAN-18-0171

Published: 15 July 2018

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Includes: Supplementary data

Journal Articles

Abstract 2768: Global DNA hypomethylation is an important feature of melanoma

Goran Micevic, Nicholas Theodosakis, Janis M. Taube, Marcus W. Bosenberg, Nemanja Rodic

Cancer Res (2016) 76 (14_Supplement): 2768.

DOI: https://doi.org/10.1158/1538-7445.AM2016-2768

Published: 15 July 2016

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Journal Articles

Abstract 2529: Debio 1143 synergizes with taxanes, topoisomerase and bromodomain inhibitors to inhibit growth of lung adenocarcinoma

Casey G. Langdon, Norbert Wiedemann, Matthew A. Held, James T. Platt, Ramanaiah Mamillapalli, Pinar Iyidogan, Nicholas Theodosakis, Frederic Levy, Denis Robichon, Claudio Zanna, Gregoire Vuagniaux, Mel Sorensen, Shaomeng Wang, Marcus W. Bosenberg, David F. Stern

Cancer Res (2015) 75 (15_Supplement): 2529.

DOI: https://doi.org/10.1158/1538-7445.AM2015-2529

Published: 01 August 2015

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Journal Articles

Abstract 5441: Debio 1143, an oral antagonist of the inhibitor of apoptosis proteins, synergistically enhances the effects of multiple standard of care agents in human lung cancer models

Casey G. Langdon, Norbert Wiedemann, Mathew A. Held, James T. Platt, Frédéric Lévy, Denis Robichon, Claudio Zanna, Grégoire Vuagniaux, Mel Sorensen, Shaomeng Wang, Marcus W. Bosenberg, David F. Stern

Cancer Res (2014) 74 (19_Supplement): 5441.

DOI: https://doi.org/10.1158/1538-7445.AM2014-5441

Published: 01 October 2014

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Journal Articles

Abstract 1792: Identification of synergistic drug combinations with the oral HSP90 inhibitor Debio 0932 in non-small cell lung cancer and renal cell cancer

Casey G. Langdon, Norbert Wiedemann, Hélène Maby-El Hajjami, Mathew A. Held, James T. Platt, Grégoire Vuagniaux, Marcus W. Bosenberg, David F. Stern, Frédéric Lévy

Cancer Res (2014) 74 (19_Supplement): 1792.

DOI: https://doi.org/10.1158/1538-7445.AM2014-1792

Published: 01 October 2014

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Journal Articles

Immune-Based Antitumor Effects of BRAF Inhibitors Rely on Signaling by CD40L and IFNγ

Ping-Chih Ho, Katrina M. Meeth, Yao-Chen Tsui, Bhaskar Srivastava, Marcus W. Bosenberg, Susan M. Kaech

Cancer Res (2014) 74 (12): 3205–3217.

DOI: https://doi.org/10.1158/0008-5472.CAN-13-3461

Published: 12 June 2014

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Includes: Supplementary data

Journal Articles

Abstract 1116: Sleeping Beauty mutagenesis identifies genes and pathways that cooperate with BrafV600E in melanoma initiation and progression.

Michael B. Mann, Michael A. Black, Jerrold M. Ward, Marcus W. Bosenberg, Martin McMahon, Cristin G. Print, David J. Adams, Neal G. Copeland, Nancy A. Jenkins

Cancer Res (2013) 73 (8_Supplement): 1116.

DOI: https://doi.org/10.1158/1538-7445.AM2013-1116

Published: 15 April 2013

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Journal Articles

Abstract 1534: CD163-expressing macrophages constitute a distinct malignancy-promoting phenotype in melanoma facilitating tumor development, progression, and metastasis: Implications for novel anticancer therapy.

Maciej B. Maniecki, Anders Etzerodt, William E. Damsky, Jr., Aisha Rafique, David Gonzalez, Lars Dyrskjøt, Holger J. Møller, Marcus W. Bosenberg, Søren K. Moestrup

Cancer Res (2013) 73 (8_Supplement): 1534.

DOI: https://doi.org/10.1158/1538-7445.AM2013-1534

Published: 15 April 2013

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Journal Articles

Abstract 539: The expression of monocyte/macrophage-restricted scavenger receptor CD163 by malignant cells may be a consequence of cell fusion with tumor-associated macrophages: A novel target for cancer therapy

Maciej B. Maniecki, William E. Damsky, Benedicte P. Ulhøi, Torben Steiniche, Torben F. Ørntoft, Lars Dyrskjøt, Michael Borre, Eigil Kjeldsen, Marcus W. Bosenberg, Holger J. Møller

Cancer Res (2011) 71 (8_Supplement): 539.

DOI: https://doi.org/10.1158/1538-7445.AM2011-539

Published: 15 April 2011

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Journal Articles

Characterization of Melanoma Cells Capable of Propagating Tumors from a Single Cell

Matthew A. Held, David P. Curley, David Dankort, Martin McMahon, Viswanathan Muthusamy, Marcus W. Bosenberg

Cancer Res (2010) 70 (1): 388–397.

DOI: https://doi.org/10.1158/0008-5472.CAN-09-2153

Published: 04 January 2010

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Includes: Supplementary data

Journal Articles

LKB1 Deficiency Sensitizes Mice to Carcinogen-Induced Tumorigenesis

Sushma Gurumurthy, Aram F. Hezel, Justin H. Berger, Marcus W. Bosenberg, Nabeel Bardeesy

Cancer Res (2008) 68 (1): 55–63.

DOI: https://doi.org/10.1158/0008-5472.CAN-07-3225

Published: 02 January 2008

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Journal Articles

Loss of Xeroderma Pigmentosum C (Xpc) Enhances Melanoma Photocarcinogenesis in Ink4a-Arf–Deficient Mice

Guang Yang, David Curley, Marcus W. Bosenberg, Hensin Tsao

Cancer Res (2007) 67 (12): 5649–5657.

DOI: https://doi.org/10.1158/0008-5472.CAN-06-3806

Published: 15 June 2007

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Includes: Supplementary data

Journal Articles

Deregulated Akt3 Activity Promotes Development of Malignant Melanoma

Jill M. Stahl, Arati Sharma, Mitchell Cheung, Melissa Zimmerman, Jin Q. Cheng, Marcus W. Bosenberg, Mark Kester, Lakshman Sandirasegarane, Gavin P. Robertson

Cancer Res (2004) 64 (19): 7002–7010.

DOI: https://doi.org/10.1158/0008-5472.CAN-04-1399

Published: 01 October 2004

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NARROW

Abstract 3424: IL-18 immunotherapy is efficacious against checkpoint-immunotherapy refractory tumors by promoting the maturation of highly proliferative, polyfunctional NK cells

Abstract 2156: IL-18 pathway agonism expands intratumoral PD1+ Tcf1+ stem-like CD8+ cells and their polyfunctional effector progeny to promote anti-tumor immunity

Abstract 4622: The YUMMER.G mouse melanoma model recapitulates the heterogeneous response to immune checkpoint blockade based on patient sex

Extracorporeal Photochemotherapy Drives Monocyte-to-Dendritic Cell Maturation to Induce Anticancer Immunity

Abstract 2768: Global DNA hypomethylation is an important feature of melanoma

Abstract 2529: Debio 1143 synergizes with taxanes, topoisomerase and bromodomain inhibitors to inhibit growth of lung adenocarcinoma

Abstract 5441: Debio 1143, an oral antagonist of the inhibitor of apoptosis proteins, synergistically enhances the effects of multiple standard of care agents in human lung cancer models

Abstract 1792: Identification of synergistic drug combinations with the oral HSP90 inhibitor Debio 0932 in non-small cell lung cancer and renal cell cancer

Immune-Based Antitumor Effects of BRAF Inhibitors Rely on Signaling by CD40L and IFNγ

Abstract 1116: Sleeping Beauty mutagenesis identifies genes and pathways that cooperate with BrafV600E in melanoma initiation and progression.

Abstract 1534: CD163-expressing macrophages constitute a distinct malignancy-promoting phenotype in melanoma facilitating tumor development, progression, and metastasis: Implications for novel anticancer therapy.

Abstract 539: The expression of monocyte/macrophage-restricted scavenger receptor CD163 by malignant cells may be a consequence of cell fusion with tumor-associated macrophages: A novel target for cancer therapy

Characterization of Melanoma Cells Capable of Propagating Tumors from a Single Cell

LKB1 Deficiency Sensitizes Mice to Carcinogen-Induced Tumorigenesis

Loss of Xeroderma Pigmentosum C (Xpc) Enhances Melanoma Photocarcinogenesis in Ink4a-Arf–Deficient Mice

Deregulated Akt3 Activity Promotes Development of Malignant Melanoma

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