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Manuela Iezzi
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Journal Articles

Abstract 2609: Vesicular LGALS3BP is a neuroblastoma biomarker and a therapeutic target for combination therapy with antibody-drug conjugate and checkpoint inhibitors

Gianluca Sala, Emily Capone, Ilaria Cela, Giulio Lovato, Alessia Lamolinara, Manuela Iezzi, Cosmo Rossi, Vincenzo De Laurenzi, Rodolfo Ippoliti, Stefano Iacobelli
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 2609.
https://doi.org/10.1158/1538-7445.AM2024-2609
Published: 22 March 2024
View article titled, Abstract 2609: Vesicular LGALS3BP is a neuroblastoma biomarker and a therapeutic target for combination therapy with antibody-drug conjugate and checkpoint inhibitors
Journal Articles

Pyrvinium Pamoate Induces Death of Triple-Negative Breast Cancer Stem–Like Cells and Reduces Metastases through Effects on Lipid Anabolism

Rosanna Dattilo, Carla Mottini, Emanuela Camera, Alessia Lamolinara, Noam Auslander, Ginevra Doglioni, Michela Muscolini, Wei Tang, Melanie Planque, Cristiana Ercolani, Simonetta Buglioni, Isabella Manni, Daniela Trisciuoglio, Alessandra Boe, Sveva Grande, Anna Maria Luciani, Manuela Iezzi, Gennaro Ciliberto, Stefan Ambs, Ruggero De Maria, Sarah-Maria Fendt, Eytan Ruppin, Luca Cardone
Journal: Cancer Research
Series: Author Choice
Cancer Res (2020) 80 (19): 4087–4102.
https://doi.org/10.1158/0008-5472.CAN-19-1184
Published: 02 October 2020
View article titled, Pyrvinium Pamoate Induces Death of Triple-Negative Breast Cancer Stem–Like Cells and Reduces Metastases through Effects on Lipid Anabolism
Open the PDF for Pyrvinium Pamoate Induces Death of Triple-Negative Breast Cancer Stem–Like Cells and Reduces Metastases through Effects on Lipid Anabolism in another window
Includes: Supplementary data
Journal Articles

Predictive Signatures Inform the Effective Repurposing of Decitabine to Treat KRAS–Dependent Pancreatic Ductal Adenocarcinoma

Carla Mottini, Hideo Tomihara, Diego Carrella, Alessia Lamolinara, Manuela Iezzi, Justin K. Huang, Carla A. Amoreo, Simonetta Buglioni, Isabella Manni, Frederick S. Robinson, Rosalba Minelli, Ya'an Kang, Jason B. Fleming, Michael P. Kim, Christopher A. Bristow, Daniela Trisciuoglio, Antonella Iuliano, Donatella Del Bufalo, Diego Di Bernardo, Davide Melisi, Giulio F. Draetta, Gennaro Ciliberto, Alessandro Carugo, Luca Cardone
Journal: Cancer Research
Series: Author Choice
Cancer Res (2019) 79 (21): 5612–5625.
https://doi.org/10.1158/0008-5472.CAN-19-0187
Published: 01 November 2019
View article titled, Predictive Signatures Inform the Effective Repurposing of Decitabine to Treat KRAS–Dependent Pancreatic Ductal Adenocarcinoma
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Includes: Supplementary data
Journal Articles

Abstract 41: An Antibody Drug Conjugate targeting HER-3 demonstrates promising antitumor efficacy in a wide range of human cancer

Gianluca Sala, Manuela Iezzi, Alessia Lamolinara, Emily Capone, Stefano Iacobelli, Jean-Fred Sauniere, Sara Ponziani, Francesco Giansanti, Rodolfo Ippoliti
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 41.
https://doi.org/10.1158/1538-7445.AM2017-41
Published: 01 July 2017
View article titled, Abstract 41: An Antibody Drug Conjugate targeting HER-3 demonstrates promising antitumor efficacy in a wide range of human cancer
Journal Articles

Abstract 1200: HER-2 isoform interaction in mammary carcinoma onset and progression

Arianna Palladini, Massimiliano Dall’Ora, Tania Balboni, Giordano Nicoletti, Marianna Ianzano, Roberta Laranga, Lorena Landuzzi, Veronica Giusti, Alessia Lamolinara, Carla De Giovanni, Augusto Amici, Serenella M. Pupa, Manuela Iezzi, Patrizia Nanni, Pier-Luigi Lollini
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 1200.
https://doi.org/10.1158/1538-7445.AM2016-1200
Published: 15 July 2016
View article titled, Abstract 1200: HER-2 isoform interaction in mammary carcinoma onset and progression
Journal Articles

Abstract 3826: Phenethyl isothiocyanate hampers growth and progression of HER2-positive breast cancers

Ada Koschorke, Lorenzo Castagnoli, Gaia C. Ghedini, Tiziana Triulzi, Claudia Chiodoni, Rossella Canese, Egidio Iorio, Manuela Iezzi, Patrizia Nanni, Elda Tagliabue, Serenella M. Pupa
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 3826.
https://doi.org/10.1158/1538-7445.AM2016-3826
Published: 15 July 2016
View article titled, Abstract 3826: Phenethyl isothiocyanate hampers growth and progression of HER2-positive breast cancers
Journal Articles

Feasibility of Telomerase-Specific Adoptive T-cell Therapy for B-cell Chronic Lymphocytic Leukemia and Solid Malignancies

Sara Sandri, Sara Bobisse, Kelly Moxley, Alessia Lamolinara, Francesco De Sanctis, Federico Boschi, Andrea Sbarbati, Giulio Fracasso, Giovanna Ferrarini, Rudi W. Hendriks, Chiara Cavallini, Maria Teresa Scupoli, Silvia Sartoris, Manuela Iezzi, Michael I. Nishimura, Vincenzo Bronte, Stefano Ugel
Journal: Cancer Research
Series: Author Choice
Cancer Res (2016) 76 (9): 2540–2551.
https://doi.org/10.1158/0008-5472.CAN-15-2318
Published: 01 May 2016
View article titled, Feasibility of Telomerase-Specific Adoptive T-cell Therapy for B-cell Chronic Lymphocytic Leukemia and Solid Malignancies
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Includes: Supplementary data
Journal Articles

Abstract 2314: d16HER2 splice variant regulates the activity of HER2-positive breast cancer-initiating cells

Lorenzo Castagnoli, Ada Koschorke, Gaia C. Ghedini, Lorenzo Galvani, Valentina Ciravolo, Cristina Ghirelli, Arianna Palladini, Alessia Lamolinara, Manuela Iezzi, Pier Luigi Lollini, Tiziana Triulzi, Patrizia Nanni, Elda Tagliabue, Serenella M. Pupa
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 2314.
https://doi.org/10.1158/1538-7445.AM2015-2314
Published: 01 August 2015
View article titled, Abstract 2314: d16HER2 splice variant regulates the activity of HER2-positive breast cancer-initiating cells
Journal Articles

Activated d16HER2 Homodimers and SRC Kinase Mediate Optimal Efficacy for Trastuzumab

Lorenzo Castagnoli, Manuela Iezzi, Gaia C. Ghedini, Valentina Ciravolo, Giulia Marzano, Alessia Lamolinara, Roberta Zappasodi, Patrizia Gasparini, Manuela Campiglio, Augusto Amici, Claudia Chiodoni, Arianna Palladini, Pier Luigi Lollini, Tiziana Triulzi, Sylvie Menard, Patrizia Nanni, Elda Tagliabue, Serenella M. Pupa
Journal: Cancer Research
Series: Author Choice
Cancer Res (2014) 74 (21): 6248–6259.
https://doi.org/10.1158/0008-5472.CAN-14-0983
Published: 30 October 2014
View article titled, Activated d16HER2 Homodimers and SRC Kinase Mediate Optimal Efficacy for Trastuzumab
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Includes: Supplementary data
Journal Articles

Abstract 2774: Coexpression of Delta16 isoform and full-length HER-2 in F1 hybrid transgenic mice: effects on tumor growth and malignancy

Pier-Luigi Lollini, Valentina Grosso, Dario Ranieri, Arianna Palladini, Marianna Ianzano, Massimiliano Dall'Ora, Lorena Landuzzi, Giordano Nicoletti, Tania Balboni, Roberta Laranga, Carla D. Giovanni, Augusto Amici, Serenella M. Pupa, Manuela Iezzi, Patrizia Nanni
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 2774.
https://doi.org/10.1158/1538-7445.AM2014-2774
Published: 01 October 2014
View article titled, Abstract 2774: Coexpression of Delta16 isoform and full-length HER-2 in F1 hybrid transgenic mice: effects on tumor growth and malignancy
Journal Articles

Abstract 1820: Dynamics of HER-2 loss in mammary carcinoma of human HER-2 trangenic mice

Patrizia Nanni, Arianna Palladini, Lorena Landuzzi, Massimiliano Dall'Ora, Marianna Ianzano, Valentina Grosso, Dario Ranieri, Giordano Nicoletti, Roberta Laranga, Carla D. Giovanni, Manuela Iezzi, Pier-Luigi Lollini
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 1820.
https://doi.org/10.1158/1538-7445.AM2014-1820
Published: 01 October 2014
View article titled, Abstract 1820: Dynamics of HER-2 loss in mammary carcinoma of human HER-2 trangenic mice
Journal Articles

Abstract 2637: Role of d16HER2 splice variant in HER2-positive breast cancer

Gaia C. Ghedini, Arianna Palladini, Valentina Ciravolo, Lorenzo Castagnoli, Giulia Marzano, Roberta Zappasodi, Guido Santilli, Augusto Amici, Alessia Lamolinara, Manuela Iezzi, Patrizia Nanni, Elda Tagliabue, Serenella M. Pupa
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 2637.
https://doi.org/10.1158/1538-7445.AM2014-2637
Published: 01 October 2014
View article titled, Abstract 2637: Role of d16HER2 splice variant in HER2-positive breast cancer
Journal Articles

Abstract 1403: Multiorogan metastasis of human HER-2+ breast cancer in immunodeficient mice

Pier-Luigi Lollini, Giordano Nicoletti, Marianna Ianzano, Stefania Croci, Valentina Grosso, Arianna Palladini, Manuela Iezzi, Lorena Landuzzi, Carla De Giovanni, Patrizia Nanni
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 1403.
https://doi.org/10.1158/1538-7445.AM2012-1403
Published: 15 April 2012
View article titled, Abstract 1403: Multiorogan metastasis of human HER-2+ breast cancer in immunodeficient mice
Journal Articles

Abstract 916: Role of delta16HER2 splice variant in HER2-driven tumor progression and response to targeted therapy

Serenella M. Pupa, Lorenzo Castagnoli, Gaia Cristina Ghedini, Roberta Zappasodi, Valentina Ciravolo, Giulia Marzano, Guido Santilli, Augusto Amici, Cristina Marchini, Massimo Di Nicola, Rossella Canese, Egidio Iorio, Manuela Iezzi, Elda Tagliabue
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 916.
https://doi.org/10.1158/1538-7445.AM2012-916
Published: 15 April 2012
View article titled, Abstract 916: Role of delta16HER2 splice variant in HER2-driven tumor progression and response to targeted therapy
Journal Articles

A Better Immune Reaction to Erbb-2 Tumors Is Elicited in Mice by DNA Vaccines Encoding Rat/Human Chimeric Proteins

Elena Quaglino, Cristina Mastini, Augusto Amici, Cristina Marchini, Manuela Iezzi, Stefania Lanzardo, Carla De Giovanni, Maura Montani, Pier-Luigi Lollini, Giuseppe Masucci, Guido Forni, Federica Cavallo
Journal: Cancer Research
Cancer Res (2010) 70 (7): 2604–2612.
https://doi.org/10.1158/0008-5472.CAN-09-2548
Published: 31 March 2010
View article titled, A Better Immune Reaction to Erbb-2 Tumors Is Elicited in Mice by DNA Vaccines Encoding Rat/Human Chimeric Proteins
Open the PDF for A Better Immune Reaction to Erbb-2 Tumors Is Elicited in Mice by DNA Vaccines Encoding Rat/Human Chimeric Proteins in another window
Includes: Supplementary data
Journal Articles

Phospholipase Cγ1 Is Required for Metastasis Development and Progression

Gianluca Sala, Francesco Dituri, Claudio Raimondi, Sara Previdi, Tania Maffucci, Marco Mazzoletti, Cosmo Rossi, Manuela Iezzi, Rossano Lattanzio, Mauro Piantelli, Stefano Iacobelli, Massimo Broggini, Marco Falasca
Journal: Cancer Research
Cancer Res (2008) 68 (24): 10187–10196.
https://doi.org/10.1158/0008-5472.CAN-08-1181
Published: 15 December 2008
View article titled, Phospholipase Cγ1 Is Required for Metastasis Development and Progression
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Includes: Supplementary data
Journal Articles

Preventive Vaccination with Telomerase Controls Tumor Growth in Genetically Engineered and Carcinogen-Induced Mouse Models of Cancer

Carmela Mennuni, Stefano Ugel, Federica Mori, Barbara Cipriani, Manuela Iezzi, Tania Pannellini, Domenico Lazzaro, Gennaro Ciliberto, Nicola La Monica, Paola Zanovello, Vincenzo Bronte, Elisa Scarselli
Journal: Cancer Research
Cancer Res (2008) 68 (23): 9865–9874.
https://doi.org/10.1158/0008-5472.CAN-08-1603
Published: 01 December 2008
View article titled, Preventive Vaccination with Telomerase Controls Tumor Growth in Genetically Engineered and Carcinogen-Induced Mouse Models of Cancer
Open the PDF for Preventive Vaccination with Telomerase Controls Tumor Growth in Genetically Engineered and Carcinogen-Induced Mouse Models of Cancer in another window
Journal Articles

Long-term prevention of HER-2/p53 driven salivary gland carcinogenesis through a multi-DNA vaccine

Arianna Palladini, Lorena Landuzzi, Stefania Croci, Giordano Nicoletti, Agnese Antognoli, Annalisa Murgo, Annalisa Astolfi, Silvano Ferrini, Marina Fabbi, Augusto Amici, Manuela Iezzi, Piero Musiani, Patrizia Nanni, Pier-Luigi Lollini, Carla De Giovanni
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 5301.
Published: 01 May 2008
View article titled, Long-term prevention of HER-2/p53 driven salivary gland carcinogenesis through a multi-DNA vaccine
Journal Articles

Antimetastatic Activity of a Preventive Cancer Vaccine

Patrizia Nanni, Giordano Nicoletti, Arianna Palladini, Stefania Croci, Annalisa Murgo, Agnese Antognoli, Lorena Landuzzi, Marina Fabbi, Silvano Ferrini, Piero Musiani, Manuela Iezzi, Carla De Giovanni, Pier-Luigi Lollini
Journal: Cancer Research
Cancer Res (2007) 67 (22): 11037–11044.
https://doi.org/10.1158/0008-5472.CAN-07-2499
Published: 15 November 2007
View article titled, Antimetastatic Activity of a Preventive Cancer Vaccine
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Journal Articles

Host Perforin Reduces Tumor Number but Does Not Increase Survival in Oncogene-Driven Mammary Adenocarcinoma

Shayna E.A. Street, Nadeen Zerafa, Manuela Iezzi, Jennifer A. Westwood, John Stagg, Piero Musiani, Mark J. Smyth
Journal: Cancer Research
Cancer Res (2007) 67 (11): 5454–5460.
https://doi.org/10.1158/0008-5472.CAN-06-4084
Published: 01 June 2007
View article titled, Host Perforin Reduces Tumor Number but Does Not Increase Survival in Oncogene-Driven Mammary Adenocarcinoma
Open the PDF for Host Perforin Reduces Tumor Number but Does Not Increase Survival in Oncogene-Driven Mammary Adenocarcinoma in another window
Includes: Supplementary data