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Manuel Perucho
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Journal Articles

Abstract 1381: Somatic DNA demethylation and epigenetic reprogramming of SST1 pericentromeric repeats associate with genomic damage in colorectal cancer

Johanna Samuelsson, Gabrijela Dumbovic, Sergio Alonso, Sonia Forcales, Manuel Perucho
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 1381.
https://doi.org/10.1158/1538-7445.AM2014-1381
Published: 01 October 2014
View article titled, Abstract 1381: Somatic DNA demethylation and epigenetic reprogramming of SST1 pericentromeric repeats associate with genomic damage in colorectal cancer
Journal Articles

Abstract 2792: Pericentromeric repeats undergo genome-wide DNA hypomethylation associated with older colorectal cancer patients without mutant p53 and are target for a reverse epigenetic switching

Johanna K. Samuelsson, Sergio Alonso, Koichi Suzuki, Manuel Perucho
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 2792.
https://doi.org/10.1158/1538-7445.AM2011-2792
Published: 15 April 2011
View article titled, Abstract 2792: Pericentromeric repeats undergo genome-wide DNA hypomethylation associated with older colorectal cancer patients without mutant p53 and are target for a reverse epigenetic switching
Journal Articles

Downregulation of EGFR gene expression in colon cancer with microsatellite instability

Svetlana Baranovskaya, Yolanda Martin, Mario Falchetti, Ksenia Pisarchuk, Yuichi Dai, Sophia Khaldoyanidi, Stan Krajewski, Manuel Perucho, Sergei Malkhosyan
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): LB-154.
Published: 01 May 2008
View article titled, Downregulation of EGFR gene expression in colon cancer with microsatellite instability
Journal Articles

Epigenetic silencing of ADAMTS19 in human cancer

Sergio Alonso, Tatiana Ruiz-Larroya, Mercedes Duran-Dominguez, Jose Bautista-Saldana, Akihiro Matsunaga, August Vidal, Enric Condom, Pepita Gimenez-Bonafe, Manuel Perucho
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 4287.
Published: 01 May 2008
View article titled, Epigenetic silencing of ADAMTS19 in human cancer
Journal Articles

Hypersensitivity of Tumor Cell Lines with Microsatellite Instability to DNA Double Strand Break Producing Chemotherapeutic Agent Bleomycin

Hai-Ri Li, Elena I. Shagisultanova, Kentaro Yamashita, Zhe Piao, Manuel Perucho, Sergei R. Malkhosyan
Journal: Cancer Research
Cancer Res (2004) 64 (14): 4760–4767.
https://doi.org/10.1158/0008-5472.CAN-04-0975
Published: 15 July 2004
View article titled, Hypersensitivity of Tumor Cell Lines with Microsatellite Instability to DNA Double Strand Break Producing Chemotherapeutic Agent Bleomycin
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Journal Articles

Low Mutation Incidence in Polymorphic Noncoding Short Mononucleotide Repeats in Gastrointestinal Cancer of the Microsatellite Mutator Phenotype Pathway

Koichi Suzuki, Tomoko Dai, Ikuko Suzuki, Yuichi Dai, Kentaro Yamashita, Manuel Perucho
Journal: Cancer Research
Cancer Res (2002) 62 (7): 1961–1965.
Published: 01 April 2002
View article titled, Low Mutation Incidence in Polymorphic Noncoding Short Mononucleotide Repeats in Gastrointestinal Cancer of the Microsatellite Mutator Phenotype Pathway
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Journal Articles

Genetic and Clinical Features of Human Pancreatic Ductal Adenocarcinomas with Widespread Microsatellite Instability

Hiroyuki Yamamoto, Fumio Itoh, Hideaki Nakamura, Hiroshi Fukushima, Shigeru Sasaki, Manuel Perucho, Kohzoh Imai
Journal: Cancer Research
Cancer Res (2001) 61 (7): 3139–3144.
Published: 01 April 2001
View article titled, Genetic and Clinical Features of Human Pancreatic Ductal Adenocarcinomas with Widespread Microsatellite Instability
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Journal Articles

Frequent Frameshift Mutations of RIZ in Sporadic Gastrointestinal and Endometrial Carcinomas with Microsatellite Instability

Zhe Piao, Wei Fang, Sergei Malkhosyan, Hoguen Kim, Akira Horii, Manuel Perucho, Shi Huang
Journal: Cancer Research
Cancer Res (2000) 60 (17): 4701–4704.
Published: 01 September 2000
View article titled, Frequent Frameshift Mutations of <em>RIZ</em> in Sporadic Gastrointestinal and Endometrial Carcinomas with Microsatellite Instability
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Journal Articles

Frameshift Mutations at Mononucleotide Repeats in caspase-5 and Other Target Genes in Endometrial and Gastrointestinal Cancer of the Microsatellite Mutator Phenotype

Simó Schwartz, Jr., Hiroyuki Yamamoto, Manuel Navarro, Marisa Maestro, Jaume Reventós, Manuel Perucho
Journal: Cancer Research
Cancer Res (1999) 59 (12): 2995–3002.
Published: 15 June 1999
View article titled, Frameshift Mutations at Mononucleotide Repeats in <em>caspase-5</em> and Other Target Genes in Endometrial and Gastrointestinal Cancer of the Microsatellite Mutator Phenotype
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Journal Articles

Impairment of the Proapoptotic Activity of Bax by Missense Mutations Found in Gastrointestinal Cancers

Joan Gil, Hiroyuki Yamamoto, Juan M. Zapata, John C. Reed, Manuel Perucho
Journal: Cancer Research
Cancer Res (1999) 59 (9): 2034–2037.
Published: 01 May 1999
View article titled, Impairment of the Proapoptotic Activity of Bax by Missense Mutations Found in Gastrointestinal Cancers
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Journal Articles

Correspondence re: C. R. Boland et al. A National Cancer Institute Workshop on Microsatellite Instability for Cancer Detection and Familial Predisposition: Development of International Criteria for the Determination of Microsatellite Instability in Colorectal Cancer. Cancer Res., 58: 5248–5257, 1998

Manuel Perucho
Journal: Cancer Research
Cancer Res (1999) 59 (1): 249–256.
Published: 01 January 1999
View article titled, Correspondence re: C. R. Boland <em>et al.</em> A National Cancer Institute Workshop on Microsatellite Instability for Cancer Detection and Familial Predisposition: Development of International Criteria for the Determination of Microsatellite Instability in Colorectal Cancer. Cancer Res., <em>58:</em> 5248–5257, 1998
Open the PDF for Correspondence re: C. R. Boland <em>et al.</em> A National Cancer Institute Workshop on Microsatellite Instability for Cancer Detection and Familial Predisposition: Development of International Criteria for the Determination of Microsatellite Instability in Colorectal Cancer. Cancer Res., <em>58:</em> 5248–5257, 1998 in another window
Journal Articles

Somatic Frameshift Mutations in DNA Mismatch Repair and Proapoptosis Genes in Hereditary Nonpolyposis Colorectal Cancer

Hiroyuki Yamamoto, Hisako Sawai, Thomas K. Weber, Miguel A. Rodriguez-Bigas, Manuel Perucho
Journal: Cancer Research
Cancer Res (1998) 58 (5): 997–1003.
Published: 01 March 1998
View article titled, Somatic Frameshift Mutations in DNA Mismatch Repair and Proapoptosis Genes in Hereditary Nonpolyposis Colorectal Cancer
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Journal Articles

Frameshift Somatic Mutations in Gastrointestinal Cancer of the Microsatellite Mutator Phenotype

Hiroyuki Yamamoto, Hisako Sawai, Manuel Perucho
Journal: Cancer Research
Cancer Res (1997) 57 (19): 4420–4426.
Published: 01 October 1997
View article titled, Frameshift Somatic Mutations in Gastrointestinal Cancer of the Microsatellite Mutator Phenotype
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Journal Articles

Chromosome 7q Allelic Losses in Pancreatic Carcinoma

Alberto Achille, Maria O. Biasi, Giuseppe Zamboni, Giuseppe Bogina, Alba R. Magalini, Paolo Pederzoli, Manuel Perucho, Aldo Scarpa
Journal: Cancer Research
Cancer Res (1996) 56 (16): 3808–3813.
Published: 01 August 1996
View article titled, Chromosome 7q Allelic Losses in Pancreatic Carcinoma
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Journal Articles

Differential Expression of the Normal and Mutated K-ras Alleles in Chemically Induced Thymic Lymphomas

Montserrat Corominas, Manuel Perucho, Elizabeth W. Newcomb, Angel Pellicer
Journal: Cancer Research
Cancer Res (1991) 51 (19): 5129–5133.
Published: 01 October 1991
View article titled, Differential Expression of the Normal and Mutated K-<em>ras</em> Alleles in Chemically Induced Thymic Lymphomas
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Journal Articles

Detection of c-K-ras Mutations in Fine Needle Aspirates from Human Pancreatic Adenocarcinomas

Darryl Shibata, Concepcion Almoguera, Kathleen Forrester, Jordan Dunitz, Sue Ellen Martin, Michele M. Cosgrove, Manuel Perucho, Norman Arnheim
Journal: Cancer Research
Cancer Res (1990) 50 (4): 1279–1283.
Published: 01 February 1990
View article titled, Detection of c-K-<em>ras</em> Mutations in Fine Needle Aspirates from Human Pancreatic Adenocarcinomas
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