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Manel Esteller
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Journal Articles

Abstract 534: Novel marginal zone lymphoma models of resistance to the dual inhibition of PI3K and BCL2

Alberto J. Arribas, Luciano Cascione, Eleonora Cannas, Helen Bellerjeau, Federica Fuzio, Aleix Noguera, Andrea Rinaldi, Manel Esteller, Emanuele Zucca, Andrea Alimonti, Davide Rossi, Anastasios Stathis, Francesco Bertoni
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 534.
https://doi.org/10.1158/1538-7445.AM2024-534
Published: 22 March 2024
View article titled, Abstract 534: Novel marginal zone lymphoma models of resistance to the dual inhibition of PI3K and BCL2
Journal Articles

Abstract LB130: Single-cell multiomics analysis of myelodysplastic syndrome predicts clinical response to DNA methylation inhibitor therapy

Ignacio Campillo-Marcos, Marta Casado-Pelaez, Veronica Davalos, Gerardo Ferrer, Caterina Mata, Elisabetta Mereu, David Valcarcel, Antonieta Molero, Lurdes Zamora, Laura Palomo, Pamela Acha, Ana Manzanares, Francesc Solé, Manel Esteller
Journal: Cancer Research
Cancer Res (2023) 83 (8_Supplement): LB130.
https://doi.org/10.1158/1538-7445.AM2023-LB130
Published: 14 April 2023
View article titled, Abstract LB130: Single-cell multiomics analysis of myelodysplastic syndrome predicts clinical response to DNA methylation inhibitor therapy
Journal Articles

Abstract 394: ERBB4-mediated signaling is a mediator of resistance to BTK and PI3K inhibitors in B cell lymphoid neoplasms

Alberto J. Arribas, Sara Napoli, Luciano Cascione, Laura Barnabei, Giulio Sartori, Eleonora Cannas, Eugenio Gaudio, Chiara Tarantelli, Afua A. Mensah, Filippo Spriano, Antonella Zucchetto, Francesca M. Rossi, Andrea Rinaldi, Manuel Castro de Moura, Anastasios Stathis, Georg Stussi, Valter Gattei, Jennifer R. Brown, Manel Esteller, Emanuele Zucca, Davide Rossi, Francesco Bertoni
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 394.
https://doi.org/10.1158/1538-7445.AM2023-394
Published: 04 April 2023
View article titled, Abstract 394: ERBB4-mediated signaling is a mediator of resistance to BTK and PI3K inhibitors in B cell lymphoid neoplasms
Journal Articles

Abstract 153: Epigenetic loss of NSUN5 in glioma drives a global protein synthesis depletion along with the emergence of a stress adaptive translational program

Vanessa Ortiz Barahona, Maxime Janin, Manel Esteller
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 153.
https://doi.org/10.1158/1538-7445.AM2020-153
Published: 15 August 2020
View article titled, Abstract 153: Epigenetic loss of NSUN5 in glioma drives a global protein synthesis depletion along with the emergence of a stress adaptive translational program
Journal Articles

Abstract 1422: Clinical association of miR-155-5p with breast cancer and its relevance for treatment with PARP inhibitors

Barbara Pasculli, Raffaela Barbano, Andrea Fontana, Tommaso Biagini, Maria Pia Di Viesti, Michelina Rendina, Vanna Maria Valori, Maria Morritti, Sara Bravaccini, Sara Ravaioli, Evaristo Maiello, Paolo Graziano, Roberto Murgo, Massimiliano Copetti, Tommaso Mazza, Vito Michele Fazio, Manel Esteller, Paola Parrella
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 1422.
https://doi.org/10.1158/1538-7445.AM2020-1422
Published: 15 August 2020
View article titled, Abstract 1422: Clinical association of miR-155-5p with breast cancer and its relevance for treatment with PARP inhibitors
Journal Articles

Abstract 5416: Positioning the NQO1-bioactivatable drug isobutyl-deoxynyboquinone in diffuse intrinsic pontine glioma (DIPG): an exceptional therapeutic opportunity in pediatric brain tumor

Maxime Henri Janin, Vanessa Ortiz Barahona, Pere Llinas Arias, Carolina De La Torre, Angel Montero Carcaboso, Andres Morales La Madrid, Paul Hergenrother, Manel Esteller
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 5416.
https://doi.org/10.1158/1538-7445.AM2020-5416
Published: 15 August 2020
View article titled, Abstract 5416: Positioning the NQO1-bioactivatable drug isobutyl-deoxynyboquinone in diffuse intrinsic pontine glioma (DIPG): an exceptional therapeutic opportunity in pediatric brain tumor
Journal Articles

Epigenetic SMAD3 Repression in Tumor-Associated Fibroblasts Impairs Fibrosis and Response to the Antifibrotic Drug Nintedanib in Lung Squamous Cell Carcinoma

Rafael Ikemori, Marta Gabasa, Paula Duch, Miguel Vizoso, Paloma Bragado, Marselina Arshakyan, Iuliana-Cristiana Luis, Albert Marín, Sebastian Morán, Manuel Castro, Gemma Fuster, Sabrina Gea-Sorli, Toni Jauset, Laura Soucek, Luis M. Montuenga, Manel Esteller, Eduard Monsó, Victor Ivo Peinado, Pere Gascon, Cristina Fillat, Frank Hilberg, Noemí Reguart, Jordi Alcaraz
Journal: Cancer Research
Cancer Res (2020) 80 (2): 276–290.
https://doi.org/10.1158/0008-5472.CAN-19-0637
Published: 15 January 2020
View article titled, Epigenetic <em>SMAD3</em> Repression in Tumor-Associated Fibroblasts Impairs Fibrosis and Response to the Antifibrotic Drug Nintedanib in Lung Squamous Cell Carcinoma
Open the PDF for Epigenetic <em>SMAD3</em> Repression in Tumor-Associated Fibroblasts Impairs Fibrosis and Response to the Antifibrotic Drug Nintedanib in Lung Squamous Cell Carcinoma in another window
Includes: Supplementary data
Journal Articles

Abstract 1225: Aberrant SMAD3 signaling in tumor-associated fibroblasts modulates fibrosis and response to the anti-fibrotic drug nintedanib in non-small cell lung cancer

Rafael Ikemori, Marta Gabasa, Miguel Vizoso, Paula Duch, Sebastian Moran, Sabrina Gea-Sorli, Paloma Bragado, Toni Jauset, Manel Esteller, Laura Soucek, Eduard Monsó, Víctor Peinado, Cristina Fillat, Frank Hilberg, Noemí Reguart, Jordi Alcaraz
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 1225.
https://doi.org/10.1158/1538-7445.AM2019-1225
Published: 01 July 2019
View article titled, Abstract 1225: Aberrant SMAD3 signaling in tumor-associated fibroblasts modulates fibrosis and response to the anti-fibrotic drug nintedanib in non-small cell lung cancer
Journal Articles

Abstract 4904: High levels of microRNA-210-3p are associated with increased risk of disease progression in breast cancer patients treated with docetaxel

BARBARA PASCULLI, RAFFAELA BARBANO, MICHELINA RENDINA, ANDREA FONTANA, MASSIMILIANO COPETTI, VANNA MARIA VALORI, MARIA MORRITTI, EVARISTO MAIELLO, VITO MICHELE FAZIO, MANEL ESTELLER, PAOLA PARRELLA
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 4904.
https://doi.org/10.1158/1538-7445.AM2019-4904
Published: 01 July 2019
View article titled, Abstract 4904: High levels of microRNA-210-3p are associated with increased risk of disease progression in breast cancer patients treated with docetaxel
Journal Articles

Abstract 466: A novel DNA methylation-based approach for molecular subtyping and improved prognostication of colorectal cancer using formalin-fixed and paraffin-embedded tissue

Trine B. Mattesen, Mads H. Rasmussen, Juan Sandoval, Halit Ongen, Sigrid S. Árnadóttir, Anders H. Madsen, Søren Laurberg, Emmanouil T. Dermitzakis, Manel Esteller, Claus L. Andersen, Jesper B. Bramsen
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 466.
https://doi.org/10.1158/1538-7445.AM2019-466
Published: 01 July 2019
View article titled, Abstract 466: A novel DNA methylation-based approach for molecular subtyping and improved prognostication of colorectal cancer using formalin-fixed and paraffin-embedded tissue
Journal Articles

Abstract 4725: Efficacy of a new small-molecule inhibitor of histone deacetylase 6 (HDAC6) in preclinical models of B-cell lymphoma and acute myeloid leukemia

Lorea Villanueva, Montserrat Perez-Salvia, Eneko Aldaba, Yosu Vara, Myriam Fabre, Cristina Ferrer, Carme Masdeu, Aizpea Zubia, Eider San Sebastian, Dorleta Otaegui, Pere Llinàs-Arias, Margalida Rosselló-Tortella, María Berdasco, Fernando Setien, Catia Moutinho, Alberto Villanueva, Eva González-Barca, Josep Muncunill, José Tomás Navarro, Miguel Ángel Piris, Fernando Cossio, Manel Esteller
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 4725.
https://doi.org/10.1158/1538-7445.AM2019-4725
Published: 01 July 2019
View article titled, Abstract 4725: Efficacy of a new small-molecule inhibitor of histone deacetylase 6 (HDAC6) in preclinical models of B-cell lymphoma and acute myeloid leukemia
Journal Articles

Abstract 474: Genome-wide DNA methylation profiling reveals novel candidate epigenetic gatekeepers in hepatocarcinogenesis

Gabriela Hernandez Meza, Johann von Felden, Amanda Craig, Sergi Sayols, Anna Portela, Manel Esteller, Myron Schwartz, Vincenzo Mazzaferro, Josep Llovet, Augusto Villanueva
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 474.
https://doi.org/10.1158/1538-7445.AM2019-474
Published: 01 July 2019
View article titled, Abstract 474: Genome-wide DNA methylation profiling reveals novel candidate epigenetic gatekeepers in hepatocarcinogenesis
Journal Articles

Abstract 1819: Non-coding RNAs as key players for understanding oncogenic pathways in ovarian cancer: Studying new therapeutic strategies

Anaís Sánchez Castillo, Cristina Oliveira Mateos, Marta Soler Riera, Manel Esteller, Sonia Guil
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 1819.
https://doi.org/10.1158/1538-7445.AM2019-1819
Published: 01 July 2019
View article titled, Abstract 1819: Non-coding RNAs as key players for understanding oncogenic pathways in ovarian cancer: Studying new therapeutic strategies
Journal Articles

Disruption of Long Noncoding RNAs Targets Cancer Hallmark Pathways in Lung Tumorigenesis

Veronica Davalos, Manel Esteller
Journal: Cancer Research
Cancer Res (2019) 79 (12): 3028–3030.
https://doi.org/10.1158/0008-5472.CAN-19-0910
Published: 14 June 2019
View article titled, Disruption of Long Noncoding RNAs Targets Cancer Hallmark Pathways in Lung Tumorigenesis
Open the PDF for Disruption of Long Noncoding RNAs Targets Cancer Hallmark Pathways in Lung Tumorigenesis in another window
Journal Articles

Abstract 5394: Initial results from TRANSCAN ERA-NET BREMIR project: MicroRNAs expression profiling for identification of breast cancer patients at high risk to develop distant metastases

Paola Parrella, Raffaela Barbano, Ella Evron, Barbara Pasculli, Orazio Palumbo, Michelina Rendina, Raffaella Stallone, Michela Coco, Andrea Fontana, Tommaso Mazza, Massimiliano Copetti, Vanna Maria Valori, Maria Morritti, Paolo Graziano, Roberto Murgo, Evaristo Maiello, Massimo Carella, Vito Michele Fazio, Manel Esteller
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 5394.
https://doi.org/10.1158/1538-7445.AM2018-5394
Published: 01 July 2018
View article titled, Abstract 5394: Initial results from TRANSCAN ERA-NET BREMIR project: MicroRNAs expression profiling for identification of breast cancer patients at high risk to develop distant metastases
Journal Articles

Abstract 2936: Molecular characterization of the immune subclass of hepatocellualr carcinoma

Daniela Sia, Yang Jiao, Iris Martinez, Olga Kuchuk, Carlos Villacorta Martin, Manuel Castro de Moura, Juan Putra, Genis Camprecios, Swan Thung, Samuel Waxman, Vincenzo Mazzaferro, Manel Esteller, Augusto Villanueva, Josep Maria Llovet
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 2936.
https://doi.org/10.1158/1538-7445.AM2017-2936
Published: 01 July 2017
View article titled, Abstract 2936: Molecular characterization of the immune subclass of hepatocellualr carcinoma
Journal Articles

Abstract 612: Methylation changes in DNA of CD8 T cells following CD137 costimulation

M. Angela Aznar, Sara Labiano, Angel Diaz-Lagares, Manel Esteller, Juan Sandoval, Ignacio Melero
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 612.
https://doi.org/10.1158/1538-7445.AM2017-612
Published: 01 July 2017
View article titled, Abstract 612: Methylation changes in DNA of CD8 T cells following CD137 costimulation
Journal Articles

Abstract 3483: Genome-wide analysis of the antisense transcriptome in cancer

Raquel Boque-Sastre, Manuel Castro de Moura, Antonio Gomez, Sònia Guil, Manel Esteller
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 3483.
https://doi.org/10.1158/1538-7445.AM2017-3483
Published: 01 July 2017
View article titled, Abstract 3483: Genome-wide analysis of the antisense transcriptome in cancer
Journal Articles

Abstract 4734: miR-9-5p expression in breast cancer correlates with hormone receptor status and affects patients survival

Raffaela Barbano, Barbara Pasculli, Michelina Rendina, Andrea Fontana, Caterina Fusilli, Massimiliano Copetti, Stefamo Castellana, Vanna Maria Valori, Maria Morritti, Paolo Graziano, Luigi Ciuffreda, Michelina Coco, Francesco Picardo, Tommaso Mazza, Ella Evron, Roberto Murgo, Evaristo Maiello, Manel Esteller, Vito Michele Fazio, Paola Parrella
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 4734.
https://doi.org/10.1158/1538-7445.AM2017-4734
Published: 01 July 2017
View article titled, Abstract 4734: miR-9-5p expression in breast cancer correlates with hormone receptor status and affects patients survival
Journal Articles

Abstract 484: Epigenetic regulation of hsa-miR-3663 in colon cancer

Laia Pique, Humberto Jorge Ferrerira, Manel Esteller
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 484.
https://doi.org/10.1158/1538-7445.AM2017-484
Published: 01 July 2017
View article titled, Abstract 484: Epigenetic regulation of hsa-miR-3663 in colon cancer