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Makoto Mark Taketo
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Journal Articles

The cAMP/PKA/CREB and TGFβ/SMAD4 Pathways Regulate Stemness and Metastatic Potential in Colorectal Cancer Cells

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Teruaki Fujishita, Yasushi Kojima, Rie Kajino-Sakamoto, Emi Mishiro-Sato, Yasuhiro Shimizu, Waki Hosoda, Rui Yamaguchi, Makoto Mark Taketo, Masahiro Aoki
Journal: Cancer Research
Cancer Res (2022) 82 (22): 4179–4190.
https://doi.org/10.1158/0008-5472.CAN-22-1369
Published: 15 November 2022
View articletitled, The cAMP/PKA/CREB and TGFβ/SMAD4 Pathways Regulate Stemness and Metastatic Potential in Colorectal Cancer Cells
Open the PDF for The cAMP/PKA/CREB and TGFβ/SMAD4 Pathways Regulate Stemness and Metastatic Potential in Colorectal Cancer Cells in another window
Includes: Supplementary data
Journal Articles

Concurrent Activation of Kras and Canonical Wnt Signaling Induces Premalignant Lesions That Progress to Extrahepatic Biliary Cancer in Mice

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Munemasa Nagao, Akihisa Fukuda, Mayuki Omatsu, Mio Namikawa, Makoto Sono, Yuichi Fukunaga, Tomonori Masuda, Osamu Araki, Takaaki Yoshikawa, Satoshi Ogawa, Kenji Masuo, Norihiro Goto, Yukiko Hiramatsu, Yu Muta, Motoyuki Tsuda, Takahisa Maruno, Yuki Nakanishi, Makoto Mark Taketo, Jorge Ferrer, Tatsuaki Tsuruyama, Yasuni Nakanuma, Kojiro Taura, Shinji Uemoto, Hiroshi Seno
Journal: Cancer Research
Cancer Res (2022) 82 (9): 1803–1817.
https://doi.org/10.1158/0008-5472.CAN-21-2176
Published: 03 May 2022
View articletitled, Concurrent Activation of Kras and Canonical Wnt Signaling Induces Premalignant Lesions That Progress to Extrahepatic Biliary Cancer in Mice
Open the PDF for Concurrent Activation of Kras and Canonical Wnt Signaling Induces Premalignant Lesions That Progress to Extrahepatic Biliary Cancer in Mice in another window
Includes: Supplementary data
Journal Articles

Abstract 440: Dual role of epithelial MyD88 inApc-mutant intestinal tumors

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Rie Kajino-Sakamoto, Teruaki Fujishita, Makoto Mark Taketo, Masahiro Aoki
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 440.
https://doi.org/10.1158/1538-7445.AM2020-440
Published: 15 August 2020
View articletitled, Abstract 440: Dual role of epithelial MyD88 inApc-mutant intestinal tumors
Journal Articles

Distinct Roles of HES1 in Normal Stem Cells and Tumor Stem-like Cells of the Intestine

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Norihiro Goto, Taro Ueo, Akihisa Fukuda, Kenji Kawada, Yoshiharu Sakai, Hiroyuki Miyoshi, Makoto Mark Taketo, Tsutomu Chiba, Hiroshi Seno
Journal: Cancer Research
Cancer Res (2017) 77 (13): 3442–3454.
https://doi.org/10.1158/0008-5472.CAN-16-3192
Published: 02 July 2017
View articletitled, Distinct Roles of HES1 in Normal Stem Cells and Tumor Stem-like Cells of the Intestine
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Includes: Supplementary data
Journal Articles

Suppressing TGFβ Signaling in Regenerating Epithelia in an Inflammatory Microenvironment Is Sufficient to Cause Invasive Intestinal Cancer

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Hiroko Oshima, Mizuho Nakayama, Tae-Su Han, Kuniko Naoi, Xiaoli Ju, Yusuke Maeda, Sylvie Robine, Kiichiro Tsuchiya, Toshiro Sato, Hiroshi Sato, Makoto Mark Taketo, Masanobu Oshima
Journal: Cancer Research
Series: Author Choice
Cancer Res (2015) 75 (4): 766–776.
https://doi.org/10.1158/0008-5472.CAN-14-2036
Published: 15 February 2015
View articletitled, Suppressing TGFβ Signaling in Regenerating Epithelia in an Inflammatory Microenvironment Is Sufficient to Cause Invasive Intestinal Cancer
Open the PDF for Suppressing TGFβ Signaling in Regenerating Epithelia in an Inflammatory Microenvironment Is Sufficient to Cause Invasive Intestinal Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract SY20-01: Role of Notch signaling in colon cancer invasion and metastasis

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Makoto Mark Taketo
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): SY20-01.
https://doi.org/10.1158/1538-7445.AM2014-SY20-01
Published: 01 October 2014
View articletitled, Abstract SY20-01: Role of Notch signaling in colon cancer invasion and metastasis
Journal Articles

Induction of Prostaglandin E2 Pathway Promotes Gastric Hamartoma Development with Suppression of Bone Morphogenetic Protein Signaling

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Hiroko Oshima, Hiraku Itadani, Hidehito Kotani, Makoto Mark Taketo, Masanobu Oshima
Journal: Cancer Research
Cancer Res (2009) 69 (7): 2729–2733.
https://doi.org/10.1158/0008-5472.CAN-08-4394
Published: 01 April 2009
View articletitled, Induction of Prostaglandin E2 Pathway Promotes Gastric Hamartoma Development with Suppression of Bone Morphogenetic Protein Signaling
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Includes: Supplementary data
Journal Articles

Hyperplastic Gastric Tumors with Spasmolytic Polypeptide–Expressing Metaplasia Caused by Tumor Necrosis Factor-α–Dependent Inflammation in Cyclooxygenase-2/Microsomal Prostaglandin E Synthase-1 Transgenic Mice

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Masanobu Oshima, Hiroko Oshima, Akihiro Matsunaga, Makoto Mark Taketo
Journal: Cancer Research
Cancer Res (2005) 65 (20): 9147–9151.
https://doi.org/10.1158/0008-5472.CAN-05-1936
Published: 17 October 2005
View articletitled, Hyperplastic Gastric Tumors with Spasmolytic Polypeptide–Expressing Metaplasia Caused by Tumor Necrosis Factor-α–Dependent Inflammation in Cyclooxygenase-2/Microsomal Prostaglandin E Synthase-1 Transgenic Mice
Open the PDF for Hyperplastic Gastric Tumors with Spasmolytic Polypeptide–Expressing Metaplasia Caused by Tumor Necrosis Factor-α–Dependent Inflammation in Cyclooxygenase-2/Microsomal Prostaglandin E Synthase-1 Transgenic Mice in another window
Journal Articles

Pivotal Role of CXCR3 in Melanoma Cell Metastasis to Lymph Nodes

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Kenji Kawada, Masahiro Sonoshita, Hiromi Sakashita, Arimichi Takabayashi, Yoshio Yamaoka, Toshiaki Manabe, Kayo Inaba, Nagahiro Minato, Masanobu Oshima, Makoto Mark Taketo
Journal: Cancer Research
Cancer Res (2004) 64 (11): 4010–4017.
https://doi.org/10.1158/0008-5472.CAN-03-1757
Published: 01 June 2004
View articletitled, Pivotal Role of CXCR3 in Melanoma Cell Metastasis to Lymph Nodes
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