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Makoto M. Taketo
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Journal Articles

Abstract 5449: Exploring signaling pathways essential for stemness and metastasis of colorectal cancer cells

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Teruaki Fujishita, Makoto M. Taketo, Masahiro Aoki
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 5449.
https://doi.org/10.1158/1538-7445.AM2024-5449
Published: 22 March 2024
View articletitled, Abstract 5449: Exploring signaling pathways essential for stemness and metastasis of colorectal cancer cells
Journal Articles

CDC42 Inhibition Suppresses Progression of Incipient Intestinal Tumors

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Ryotaro Sakamori, Shiyan Yu, Xiao Zhang, Andrew Hoffman, Jiaxin Sun, Soumyashree Das, Pavan Vedula, Guangxun Li, Jiang Fu, Francesca Walker, Chung S. Yang, Zheng Yi, Wei Hsu, Da-Hai Yu, Lanlan Shen, Alexis J. Rodriguez, Makoto M. Taketo, Edward M. Bonder, Michael P. Verzi, Nan Gao
Journal: Cancer Research
Series: Author Choice
Cancer Res (2014) 74 (19): 5480–5492.
https://doi.org/10.1158/0008-5472.CAN-14-0267
Published: 30 September 2014
View articletitled, CDC42 Inhibition Suppresses Progression of Incipient Intestinal Tumors
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Includes: Supplementary data
Journal Articles

KLF5 Regulates the Integrity and Oncogenicity of Intestinal Stem Cells

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Takeo Nakaya, Seishi Ogawa, Ichiro Manabe, Masami Tanaka, Masashi Sanada, Toshiro Sato, Makoto M. Taketo, Kazuki Nakao, Hans Clevers, Masashi Fukayama, Masahiko Kuroda, Ryozo Nagai
Journal: Cancer Research
Series: Author Choice
Cancer Res (2014) 74 (10): 2882–2891.
https://doi.org/10.1158/0008-5472.CAN-13-2574
Published: 14 May 2014
View articletitled, KLF5 Regulates the Integrity and Oncogenicity of Intestinal Stem Cells
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Includes: Supplementary data
Journal Articles

Significance and Mechanism of Lymph Node Metastasis in Cancer Progression

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Kenji Kawada, Makoto M. Taketo
Journal: Cancer Research
Cancer Res (2011) 71 (4): 1214–1218.
https://doi.org/10.1158/0008-5472.CAN-10-3277
Published: 14 February 2011
View articletitled, Significance and Mechanism of Lymph Node Metastasis in Cancer Progression
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Journal Articles

Suppression of Colonic Polyposis by Homeoprotein CDX2 through its Nontranscriptional Function that Stabilizes p27Kip1

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Koji Aoki, Fumihiko Kakizaki, Hiromi Sakashita, Toshiaki Manabe, Masahiro Aoki, Makoto M. Taketo
Journal: Cancer Research
Cancer Res (2011) 71 (2): 593–602.
https://doi.org/10.1158/0008-5472.CAN-10-2842
Published: 13 January 2011
View articletitled, Suppression of Colonic Polyposis by Homeoprotein CDX2 through its Nontranscriptional Function that Stabilizes p27Kip1
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Includes: Supplementary data
Journal Articles

Keeping Out the Bad Guys: Gateway to Cellular Target Therapy

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Takanori Kitamura, Makoto M. Taketo
Journal: Cancer Research
Cancer Res (2007) 67 (21): 10099–10102.
https://doi.org/10.1158/0008-5472.CAN-07-2100
Published: 01 November 2007
View articletitled, Keeping Out the Bad Guys: Gateway to Cellular Target Therapy
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Journal Articles

TNF-α-dependent inflammation causes development of hyperplastic gastric tumors in transgenic mice expressing COX-2 and mPGES-1

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Masanobu Oshima, Hiroko Oshima, Akihiko Matsunaga, Makoto M. Taketo
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 556.
Published: 15 April 2006
View articletitled, TNF-α-dependent inflammation causes development of hyperplastic gastric tumors in transgenic mice expressing COX-2 and mPGES-1
Journal Articles

Misregulated Wnt/β-Catenin Signaling Leads to Ovarian Granulosa Cell Tumor Development

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Derek Boerboom, Marilene Paquet, Minnie Hsieh, Jinsong Liu, Soazik P. Jamin, Richard R. Behringer, Jean Sirois, Makoto M. Taketo, JoAnne S. Richards
Journal: Cancer Research
Cancer Res (2005) 65 (20): 9206–9215.
https://doi.org/10.1158/0008-5472.CAN-05-1024
Published: 17 October 2005
View articletitled, Misregulated Wnt/β-Catenin Signaling Leads to Ovarian Granulosa Cell Tumor Development
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Includes: Supplementary data
Journal Articles

The Threshold Level of Adenomatous Polyposis Coli Protein for Mouse Intestinal Tumorigenesis

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Qin Li, Tomo-o Ishikawa, Masanobu Oshima, Makoto M. Taketo
Journal: Cancer Research
Cancer Res (2005) 65 (19): 8622–8627.
https://doi.org/10.1158/0008-5472.CAN-05-2145
Published: 03 October 2005
View articletitled, The Threshold Level of Adenomatous Polyposis Coli Protein for Mouse Intestinal Tumorigenesis
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Journal Articles

Hyperplastic tumors in grandular stomach of COX-2/mPGES-1 transgenic mice.

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Masanobu Oshima, Hiroko Oshima, Makoto M. Taketo
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 547.
Published: 01 April 2004
View articletitled, Hyperplastic tumors in grandular stomach of COX-2/mPGES-1 transgenic mice.
Journal Articles

Hepatocarcinogenesis in Mice with β-Catenin and Ha-Ras Gene Mutations

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Naomoto Harada, Hiroko Oshima, Masahiro Katoh, Yositaka Tamai, Masanobu Oshima, Makoto M. Taketo
Journal: Cancer Research
Cancer Res (2004) 64 (1): 48–54.
https://doi.org/10.1158/0008-5472.CAN-03-2123
Published: 16 January 2004
View articletitled, Hepatocarcinogenesis in Mice with β-Catenin and Ha-Ras Gene Mutations
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Journal Articles

Cooperation of Cyclooxygenase 1 and Cyclooxygenase 2 in Intestinal Polyposis

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Haruna Takeda, Masahiro Sonoshita, Hiroko Oshima, Ken-ichi Sugihara, Patricia C. Chulada, Robert Langenbach, Masanobu Oshima, Makoto M. Taketo
Journal: Cancer Research
Cancer Res (2003) 63 (16): 4872–4877.
Published: 26 August 2003
View articletitled, Cooperation of Cyclooxygenase 1 and Cyclooxygenase 2 in Intestinal Polyposis
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Journal Articles

Cyclooxygenase-2 Expression in Fibroblasts and Endothelial Cells of Intestinal Polyps

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Masahiro Sonoshita, Kazuaki Takaku, Masanobu Oshima, Ken-ichi Sugihara, Makoto M. Taketo
Journal: Cancer Research
Cancer Res (2002) 62 (23): 6846–6849.
Published: 01 December 2002
View articletitled, Cyclooxygenase-2 Expression in Fibroblasts and Endothelial Cells of Intestinal Polyps
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Journal Articles

Hepatocellular Carcinoma Caused by Loss of Heterozygosity in Lkb1 Gene Knockout Mice

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Masayuki Nakau, Hiroyuki Miyoshi, Michael F. Seldin, Masayuki Imamura, Masanobu Oshima, Makoto M. Taketo
Journal: Cancer Research
Cancer Res (2002) 62 (16): 4549–4553.
Published: 15 August 2002
View articletitled, Hepatocellular Carcinoma Caused by Loss of Heterozygosity in Lkb1 Gene Knockout Mice
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Journal Articles

No Effects of Smad2 ( Madh2 ) Null Mutation on Malignant Progression of Intestinal Polyps in Apc Δ716 Knockout Mice

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Kazuaki Takaku, Jeffrey L. Wrana, Elizabeth J. Robertson, Makoto M. Taketo
Journal: Cancer Research
Cancer Res (2002) 62 (16): 4558–4561.
Published: 15 August 2002
View articletitled, No Effects of Smad2 ( Madh2 ) Null Mutation on Malignant Progression of Intestinal Polyps in Apc Δ716 Knockout Mice
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Journal Articles

Gastrointestinal Hamartomatous Polyposis in Lkb1 Heterozygous Knockout Mice

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Hiroyuki Miyoshi, Masayuki Nakau, Tomo-o Ishikawa, Michael F. Seldin, Masanobu Oshima, Makoto M. Taketo
Journal: Cancer Research
Cancer Res (2002) 62 (8): 2261–2266.
Published: 01 April 2002
View articletitled, Gastrointestinal Hamartomatous Polyposis in Lkb1 Heterozygous Knockout Mice
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Journal Articles

Lack of Tumorigenesis in the Mouse Liver after Adenovirus-mediated Expression of a Dominant Stable Mutant of β-Catenin

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Naomoto Harada, Hiroyuki Miyoshi, Naomi Murai, Hiroko Oshima, Yoshitaka Tamai, Masanobu Oshima, Makoto M. Taketo
Journal: Cancer Research
Cancer Res (2002) 62 (7): 1971–1977.
Published: 01 April 2002
View articletitled, Lack of Tumorigenesis in the Mouse Liver after Adenovirus-mediated Expression of a Dominant Stable Mutant of β-Catenin
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Journal Articles

Cyclooxygenase 2- and Prostaglandin E2 Receptor EP2-dependent Angiogenesis in ApcΔ716 Mouse Intestinal Polyps

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Hiroshi Seno, Masanobu Oshima, Tomo-o Ishikawa, Hiroko Oshima, Kazuaki Takaku, Tsutomu Chiba, Shuh Narumiya, Makoto M. Taketo
Journal: Cancer Research
Cancer Res (2002) 62 (2): 506–511.
Published: 01 January 2002
View articletitled, Cyclooxygenase 2- and Prostaglandin E2 Receptor EP2-dependent Angiogenesis in ApcΔ716 Mouse Intestinal Polyps
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Journal Articles

Chemoprevention of Intestinal Polyposis in the ApcΔ716 Mouse by Rofecoxib, a Specific Cyclooxygenase-2 Inhibitor

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Masanobu Oshima, Naomi Murai(Hata), Stacia Kargman, Meztli Arguello, Pauline Luk, Elizabeth Kwong, Makoto M. Taketo, Jilly F. Evans
Journal: Cancer Research
Cancer Res (2001) 61 (4): 1733–1740.
Published: 02 February 2001
View articletitled, Chemoprevention of Intestinal Polyposis in the ApcΔ716 Mouse by Rofecoxib, a Specific Cyclooxygenase-2 Inhibitor
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Journal Articles

Gastric and Duodenal Polyps in Smad4 (Dpc4) Knockout Mice

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Kazuaki Takaku, Hiroyuki Miyoshi, Akihiro Matsunaga, Masanobu Oshima, Nobuya Sasaki, Makoto M. Taketo
Journal: Cancer Research
Cancer Res (1999) 59 (24): 6113–6117.
Published: 15 December 1999
View articletitled, Gastric and Duodenal Polyps in Smad4 (Dpc4) Knockout Mice
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