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Journal Articles

Analysis of Tumor-Associated AXIN1 Missense Mutations Identifies Variants That Activate β-Catenin Signaling

Ruyi Zhang, Shanshan Li, Kelly Schippers, Yunlong Li, Boaz Eimers, Marla Lavrijsen, Ling Wang, Guofei Cui, Xin Chen, Maikel P. Peppelenbosch, Joyce H.G. Lebbink, Ron Smits

Cancer Res (2024) 84 (9): 1443–1459.

https://doi.org/10.1158/0008-5472.CAN-23-2268

Published: 02 May 2024

View articletitled, Analysis of Tumor-Associated AXIN1 Missense Mutations Identifies Variants That Activate β-Catenin Signaling

Includes: Supplementary data

Journal Articles

Abstract A29: Involvement of JAK-STAT signaling in human pancreatic adenocarcinoma cell lines and suitability for targeted therapy

Jesse Fest, Gwenny M. Fuhler, Peter M. van Koetsveld, Maikel P. Peppelenbosch, Casper HJ van Eijck

Cancer Res (2016) 76 (24_Supplement): A29.

https://doi.org/10.1158/1538-7445.PANCA16-A29

Published: 14 December 2016

View articletitled, Abstract A29: Involvement of JAK-STAT signaling in human pancreatic adenocarcinoma cell lines and suitability for targeted therapy

Journal Articles

Meeting Report Europhosphatase 2015: Phosphatases as Drug Targets in Cancer

Elmer Hoekstra, Maikel P. Peppelenbosch, Gwenny M. Fuhler

Cancer Res (2016) 76 (2): 193–196.

https://doi.org/10.1158/0008-5472.CAN-15-2091

Published: 14 January 2016

View articletitled, Meeting Report Europhosphatase 2015: Phosphatases as Drug Targets in Cancer

Journal Articles

Abstract 1941: TRAIL-induced kinase activation in Non small cell lung cancer cells

Kaamar Azijli, Saravanan Yuvaraaj, Maikel P. Peppelenbosch, Henk Dekker, Jos Joore, Godefridus J. Peters, Steven de Jong, Frank AE Kruyt

Cancer Res (2011) 71 (8_Supplement): 1941.

https://doi.org/10.1158/1538-7445.AM2011-1941

Published: 15 April 2011

View articletitled, Abstract 1941: TRAIL-induced kinase activation in Non small cell lung cancer cells

Journal Articles

Abstract 1974: EphB2 signaling activity plays a vital role in medulloblastoma cell adhesion and invasion

Arend H. Sikkema, Wilfred F.A. den Dunnen, Sander H. Diks, Kim R. Kampen, Frank J.G. Scherpen, Dannis G. van Vuurden, Esther Hulleman, Willem A. Kamps, Maikel P. Peppelenbosch, Eveline S.J.M. de Bont

Cancer Res (2011) 71 (8_Supplement): 1974.

https://doi.org/10.1158/1538-7445.AM2011-1974

Published: 15 April 2011

View articletitled, Abstract 1974: EphB2 signaling activity plays a vital role in medulloblastoma cell adhesion and invasion

Journal Articles

Abstract 2377: Aminopeptidase A plays a role in VEGF-induced migration and proliferation through direct activation by VEGFR2 kinase activity

Arend H. Sikkema, Eveline S. de Bont, Sander H. Diks, Arja ter Elst, Rob Ruijtenbeek, Piet J. Boender, Eelco W. Hoving, Willem A. Kamps, Wilfred F. den Dunnen, Maikel P. Peppelenbosch

Cancer Res (2010) 70 (8_Supplement): 2377.

https://doi.org/10.1158/1538-7445.AM10-2377

Published: 15 April 2010

View articletitled, Abstract 2377: Aminopeptidase A plays a role in VEGF-induced migration and proliferation through direct activation by VEGFR2 kinase activity

Journal Articles

Abstract 2386: High-throughput assessment of the VEGFR2 kinase activity profile in pediatric brain tumor tissue

Arend H. Sikkema, Eveline S. de Bont, Grietje Molema, Anna Dimberg, Peter J. Zwiers, Sander H. Diks, Eelco W. Hoving, Willem A. Kamps, Maikel P. Peppelenbosch, Wilfred F. den Dunnen

Cancer Res (2010) 70 (8_Supplement): 2386.

https://doi.org/10.1158/1538-7445.AM10-2386

Published: 15 April 2010

View articletitled, Abstract 2386: High-throughput assessment of the VEGFR2 kinase activity profile in pediatric brain tumor tissue

Journal Articles

Kinome Profiling of Clinical Cancer Specimens

Kaushal Parikh, Maikel P. Peppelenbosch

Cancer Res (2010) 70 (7): 2575–2578.

https://doi.org/10.1158/0008-5472.CAN-09-3989

Published: 31 March 2010

View articletitled, Kinome Profiling of Clinical Cancer Specimens

Journal Articles

Kinome Profiling in Pediatric Brain Tumors as a New Approach for Target Discovery

Arend H. Sikkema, Sander H. Diks, Wilfred F.A. den Dunnen, Arja ter Elst, Frank J.G. Scherpen, Eelco W. Hoving, Rob Ruijtenbeek, Piet J. Boender, Rik de Wijn, Willem A. Kamps, Maikel P. Peppelenbosch, Eveline S.J.M. de Bont

Cancer Res (2009) 69 (14): 5987–5995.

https://doi.org/10.1158/0008-5472.CAN-08-3660

Published: 15 July 2009

View articletitled, Kinome Profiling in Pediatric Brain Tumors as a New Approach for Target Discovery

Includes: Supplementary data

Journal Articles

Cyclooxygenase-2 Inhibition Inhibits c-Met Kinase Activity and Wnt Activity in Colon Cancer

Jurriaan B. Tuynman, Louis Vermeulen, Elles M. Boon, Kristel Kemper, Aeilko H. Zwinderman, Maikel P. Peppelenbosch, Dirk J. Richel

Cancer Res (2008) 68 (4): 1213–1220.

https://doi.org/10.1158/0008-5472.CAN-07-5172

Published: 15 February 2008

View articletitled, Cyclooxygenase-2 Inhibition Inhibits c-Met Kinase Activity and Wnt Activity in Colon Cancer

Journal Articles

Bone Morphogenetic Protein Signaling Suppresses Tumorigenesis at Gastric Epithelial Transition Zones in Mice

Sylvia A. Bleuming, Xi C. He, Liudmila L. Kodach, James C. Hardwick, Frieda A. Koopman, Fiebo J. ten Kate, Sander J.H. van Deventer, Daniel W. Hommes, Maikel P. Peppelenbosch, G. Johan Offerhaus, Linheng Li, Gijs R. van den Brink

Cancer Res (2007) 67 (17): 8149–8155.

https://doi.org/10.1158/0008-5472.CAN-06-4659

Published: 05 September 2007

View articletitled, Bone Morphogenetic Protein Signaling Suppresses Tumorigenesis at Gastric Epithelial Transition Zones in Mice

Journal Articles

Comparison of Kinome Profiles of Barrett's Esophagus with Normal Squamous Esophagus and Normal Gastric Cardia

Jantine W.P.M. van Baal, Sander H. Diks, Ronald J.A. Wanders, Agnieskza M. Rygiel, Francesca Milano, Jos Joore, Jacques J.G.H.M. Bergman, Maikel P. Peppelenbosch, Kausilia K. Krishnadath

Cancer Res (2006) 66 (24): 11605–11612.

https://doi.org/10.1158/0008-5472.CAN-06-1370

Published: 18 December 2006

View articletitled, Comparison of Kinome Profiles of Barrett's Esophagus with Normal Squamous Esophagus and Normal Gastric Cardia

Includes: Supplementary data

Journal Articles

Dendritic cell immunotherapy for esophageal adenocarcinoma: an ex-vivo validation study

Francesca Milano, Jantine Vanbaal, Agnieszka Rygiel, Jacques J. Bergman, Carine Sondermeijer, Maikel P. Peppelenbosch, Kausilia K. Krishnadath

Cancer Res (2006) 66 (8_Supplement): 743–744.

Published: 15 April 2006

View articletitled, Dendritic cell immunotherapy for esophageal adenocarcinoma: an ex-vivo validation study

Journal Articles

Bone Morphogenetic Protein (BMP)-4-mediated transformation of inflamed squamous esophageal mucosa into Barrett’s esophagus

Jantine W. Vanbaal, Francesca Milano, Navtej Buttar, Agnieszka Rygiel, Floor Dekort, Wilda Rosmolen, Jacques J. Bergman, Kenneth K. Wang, Maikel P. Peppelenbosch, Kausilia K. Krishnadath

Cancer Res (2006) 66 (8_Supplement): 398–399.

Published: 15 April 2006

View articletitled, Bone Morphogenetic Protein (BMP)-4-mediated transformation of inflamed squamous esophageal mucosa into Barrett’s esophagus

Journal Articles

Mesalazine acts directly on the Wnt/β-catenin pathway via protein phosphatase 2A

Carina L. Bos, Sander H. Diks, James C. H. Hardwick, Kimberley V. Walburg, Maikel P. Peppelenbosch, Dick J. Richel

Cancer Res (2005) 65 (9_Supplement): 1306.

Published: 01 May 2005

View articletitled, Mesalazine acts directly on the Wnt/β-catenin pathway via protein phosphatase 2A

Journal Articles

Celecoxib directly inhibits c-Met activation resulting in decreased oncogenic β-catenin signaling in colorectal cancer

Jurriaan B. Tuynman, Elles M. Boon, Kristel Kemper, Ronald Van der Neut, Maikel P. Peppelenbosch, Dirk J. Richel

Cancer Res (2005) 65 (9_Supplement): 605.

Published: 01 May 2005

View articletitled, Celecoxib directly inhibits c-Met activation resulting in decreased oncogenic β-catenin signaling in colorectal cancer

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Analysis of Tumor-Associated AXIN1 Missense Mutations Identifies Variants That Activate β-Catenin Signaling

Abstract A29: Involvement of JAK-STAT signaling in human pancreatic adenocarcinoma cell lines and suitability for targeted therapy

Meeting Report Europhosphatase 2015: Phosphatases as Drug Targets in Cancer

Abstract 1941: TRAIL-induced kinase activation in Non small cell lung cancer cells

Abstract 1974: EphB2 signaling activity plays a vital role in medulloblastoma cell adhesion and invasion

Abstract 2377: Aminopeptidase A plays a role in VEGF-induced migration and proliferation through direct activation by VEGFR2 kinase activity

Abstract 2386: High-throughput assessment of the VEGFR2 kinase activity profile in pediatric brain tumor tissue

Kinome Profiling of Clinical Cancer Specimens

Kinome Profiling in Pediatric Brain Tumors as a New Approach for Target Discovery

Cyclooxygenase-2 Inhibition Inhibits c-Met Kinase Activity and Wnt Activity in Colon Cancer

Bone Morphogenetic Protein Signaling Suppresses Tumorigenesis at Gastric Epithelial Transition Zones in Mice

Comparison of Kinome Profiles of Barrett's Esophagus with Normal Squamous Esophagus and Normal Gastric Cardia

Dendritic cell immunotherapy for esophageal adenocarcinoma: an ex-vivo validation study

Bone Morphogenetic Protein (BMP)-4-mediated transformation of inflamed squamous esophageal mucosa into Barrett’s esophagus

Mesalazine acts directly on the Wnt/β-catenin pathway via protein phosphatase 2A

Celecoxib directly inhibits c-Met activation resulting in decreased oncogenic β-catenin signaling in colorectal cancer

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