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Journal Articles

Abstract 6316: Predictive performance comparison of foundational and CNN models for single-cell immune profiling

Free
Colwyn Jia Kang Lai, Wei Kit Tan, Marcia Zhang, Timothy Wang, Felicia Wee, Ai Lin Wang, Solomonraj Wilson, Tomotaka Ugai, Joe Sheng Yeong Poh, Jonathan A. Nowak, Shuji Ogino, Juha P. Väyrynen, Mai Chan Lau
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 6316.
https://doi.org/10.1158/1538-7445.AM2025-6316
Published: 21 April 2025
View articletitled, Abstract 6316: Predictive performance comparison of foundational and CNN models for single-cell immune profiling
Journal Articles

Abstract 5063: Hepatomap: An interactive shiny app for spatial transcriptomics insights in hepatocellular carcinoma

Free
Wei Lin Tang, Teresa J. Tye, Menaka Priyadharsani Rajapakse, Solomonraj Wilson, Olaf RÖtzschke, David Tai, Darren Wan-Teck Lim, Juha P. Väyrynen, Joe Poh Sheng Yeong, Mai Chan Lau
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 5063.
https://doi.org/10.1158/1538-7445.AM2025-5063
Published: 21 April 2025
View articletitled, Abstract 5063: Hepatomap: An interactive shiny app for spatial transcriptomics insights in hepatocellular carcinoma
Journal Articles

Abstract 151: Spatial patterns of APOBEC mutagenesis in the tumor microenvironment of Asian breast cancer

Free
Zi Ching Tan, Yang Wu, Zhen Wei Neo, Mai Chan Lau, Siow Wee Chang, Joe Poh Sheng Yeong, Soo-Hwang Teo, Jia Wern Pan
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 151.
https://doi.org/10.1158/1538-7445.AM2025-151
Published: 21 April 2025
View articletitled, Abstract 151: Spatial patterns of APOBEC mutagenesis in the tumor microenvironment of Asian breast cancer
Journal Articles

Abstract 5087: Single cell AI-prediction of protein biomarker on novel whole slide unstained blood smear images

Free
Felicia Wee, Willa Wen-You Yim, Jia Meng, Jeffrey Lim, Li Yen Chong, Craig Ryan Joseph, Lee Hong Song, Jabed Iqbal, Mai Chan Lau, Darren Wan-Teck Lim, Joe Yeong
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 5087.
https://doi.org/10.1158/1538-7445.AM2025-5087
Published: 21 April 2025
View articletitled, Abstract 5087: Single cell AI-prediction of protein biomarker on novel whole slide unstained blood smear images
Journal Articles

Abstract 3597: Tumor bacteria, tumor-infiltrating T cells, and colorectal cancer survival outcomes

Free
Tomotaka Ugai, Jennifer Borowsky, Yuxue Zhong, Satoko Ugai, Mai Chan Lau, Kota Arima, Koichiro Haruki, Marios Giannakis, Jonathan Nowak, Shuji Ogino
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 3597.
https://doi.org/10.1158/1538-7445.AM2025-3597
Published: 21 April 2025
View articletitled, Abstract 3597: Tumor bacteria, tumor-infiltrating T cells, and colorectal cancer survival outcomes
Journal Articles

Abstract LT09: Integrative Multi-Omics Enhancer Activity Profiling Identifies Therapeutic Vulnerabilities in Cholangiocarcinoma of Different Etiologies

Free
Jing Han Hong, Chern Han Yong, Hong Lee Heng, Jason Yongsheng Chan, Mai Chan Lau, Jianfeng Chen, Jing Yi Lee, Abner Herbert Lim, Zhimei Li, Peiyong Guan, Pek Lim Chu, Sheng Rong Ng, Xiaosai Yao, Peili Wang, Rong Xiao, Xian Zeng, Yichen Sun, Wei Liu, Joanna Koh, Felicia Yu Ting Wee, Jeffrey Chun Tatt Lim, Cedric Chuan Young Ng, Xiu Yi Kwek, Poramate Klanrit, Yaojun Zhang, Jiaming Lai, David Wai Meng Tai, Chawalit Pairojkul, Simona Dima, Irinel Popescu, Sen-Yung Hsieh, Ming-Chin Yu, Joe Yeong, Sarinya Kongpetch, Apinya Jusakul, Watcharin Loilome, Patrick Tan, Jing Tan, Bin Tean Teh
Journal: Cancer Research
Cancer Res (2024) 84 (8_Supplement): LT09.
https://doi.org/10.1158/1538-7445.FCS2023-LT09
Published: 15 April 2024
View articletitled, Abstract LT09: Integrative Multi-Omics Enhancer Activity Profiling Identifies Therapeutic Vulnerabilities in Cholangiocarcinoma of Different Etiologies
Journal Articles

Abstract LB252: iCellSight: An interactive tool for analyzing and visualizing in-situ high-plex cellular protein data

Free
Yancun Zhu, Felicia Wee, Menaka Priyadharsani Rajapakse, Esther Gek Teo, Nicholas Ang, Solomonraj Wilson, Zheng Yi Ho, Willa Wen-You Yim, Li Yen Chong, Craig Ryan Joseph, Jeffrey Chun Lim, Zhen Wei Neo, Chwee Ming Lim, Bernett Lee, Olaf Rotzschke, Joe Yeong, Mai Chan Lau
Journal: Cancer Research
Cancer Res (2024) 84 (7_Supplement): LB252.
https://doi.org/10.1158/1538-7445.AM2024-LB252
Published: 05 April 2024
View articletitled, Abstract LB252: iCellSight: An interactive tool for analyzing and visualizing in-situ high-plex cellular protein data
Journal Articles

Spatially Resolved Single-Cell Assessment of Pancreatic Cancer Expression Subtypes Reveals Co-expressor Phenotypes and Extensive Intratumoral Heterogeneity

Available to Purchase
Hannah L. Williams, Andressa Dias Costa, Jinming Zhang, Srivatsan Raghavan, Peter S. Winter, Kevin S. Kapner, Scott P. Ginebaugh, Sara A. Väyrynen, Juha P. Väyrynen, Chen Yuan, Andrew W. Navia, Junning Wang, Annan Yang, Timothy L. Bosse, Radha L. Kalekar, Kristen E. Lowder, Mai Chan Lau, Dalia Elganainy, Vicente Morales-Oyarvide, Douglas A. Rubinson, Harshabad Singh, Kimberly Perez, James M. Cleary, Thomas E. Clancy, Jiping Wang, Joseph D. Mancias, Lauren K. Brais, Emma R. Hill, Margaret M. Kozak, David C. Linehan, Richard F. Dunne, Daniel T. Chang, Albert C. Koong, Aram F. Hezel, William C. Hahn, Alex K. Shalek, Andrew J. Aguirre, Jonathan A. Nowak, Brian M. Wolpin
Journal: Cancer Research
Cancer Res (2023) 83 (3): 441–455.
https://doi.org/10.1158/0008-5472.CAN-22-3050
Published: 03 February 2023
View articletitled, Spatially Resolved Single-Cell Assessment of Pancreatic Cancer Expression Subtypes Reveals Co-expressor Phenotypes and Extensive Intratumoral Heterogeneity
Open the PDF for Spatially Resolved Single-Cell Assessment of Pancreatic Cancer Expression Subtypes Reveals Co-expressor Phenotypes and Extensive Intratumoral Heterogeneity in another window
Includes: Supplementary data
Journal Articles

Abstract 684: Body mass index throughout adulthood and incidence of colorectal cancer subclassified by T cell, macrophage, and myeloid cell infiltrates in cancer tissue

Free
Tomotaka Ugai, Juha P. Väyrynen, Yasutoshi Takashima, Seyed Mostafa Mousavi Kahaki, Benjamin Langworthy, Koichiro Haruki, Naohiko Akimoto, Mai Chan Lau, Rong Zhong, Sara A. Väyrynen, Melissa Zhao, Andressa Dias Costa, Jennifer Borowsky, Jennifer L. Guerriero, Xuehong Zhang, Andrew T. Chan, Molin Wang, Marios Giannakis, Jeffrey A. Meyerhardt, Edward L. Giovannucci, Jonathan A. Nowak, Shuji Ogino
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 684.
https://doi.org/10.1158/1538-7445.AM2022-684
Published: 15 June 2022
View articletitled, Abstract 684: Body mass index throughout adulthood and incidence of colorectal cancer subclassified by T cell, macrophage, and myeloid cell infiltrates in cancer tissue
Journal Articles

Abstract 2733: Smoking and colorectal cancer Iincidence by tumor microenvironment in cancer tissue

Free
Tomotaka Ugai, Juha P. Väyrynen, Koichiro Haruki, Naohiko Akimoto, Mai Chan Lau, Rong Zhong, Sara A. Väyrynen, Melissa Zhao, Andressa Dias Costa, Jennifer Borowsky, Jennifer L. Guerriero, Charles S. Fuchs, Xuehong Zhang, Molin Wang, Marios Giannakis, Jeffrey A. Meyerhardt, Jonathan A. Nowak, Shuji Ogino
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2733.
https://doi.org/10.1158/1538-7445.AM2021-2733
Published: 01 July 2021
View articletitled, Abstract 2733: Smoking and colorectal cancer Iincidence by tumor microenvironment in cancer tissue
Journal Articles

Abstract PR-006: Spatially resolved, single cell assessment of pancreatic ductal adenocarcinoma expression subtypes reveals mixed and hybrid basal-classical marker expression with prognostic significance and discrete spatial localization

Free
Hannah L. Williams, Jinming Zhang, Srivatsan Raghavan, Peter S. Winter, Kevin Kapner, Sara Vayrynen, Andressa Dias Costa, Chen Yuan, Mai Chan Lau, Vicente Morales-Oyarvide, Douglas Rubinson, Lauren Brais, Emma Reilly, Margaret Kozak, David Linehan, Richard Dunne, Daniel Chang, Albert Koong, Aram Hezel, William C. Hahn, Alek K. Shalek, Andrew J. Aguirre, Jonathan A. Nowak, Brian M Wolpin
Journal: Cancer Research
Cancer Res (2020) 80 (22_Supplement): PR-006.
https://doi.org/10.1158/1538-7445.PANCA20-PR-006
Published: 13 November 2020
View articletitled, Abstract PR-006: Spatially resolved, single cell assessment of pancreatic ductal adenocarcinoma expression subtypes reveals mixed and hybrid basal-classical marker expression with prognostic significance and discrete spatial localization
Journal Articles

Abstract PR-001: Neoadjuvant therapy is associated with altered composition of immune cell infiltration and an anti-tumorigenic microenvironment in resected pancreatic cancer

Free
Andressa Dias Costa, Sara Väyrynen, Akhil Chawla, Jinming Zhang, Juha P. Väyrynen, Mai Chan Lau, Hannah L. Williams, Chen Yuan, Vicente Morales-Oyarvide, Douglas A. Rubinson, Thomas E. Clancy, Lauren K. Brais, Emma Reilly, Margaret M. Kozak, David C. Linehan, Richard F. Dunne, Daniel T. Chang, Aram F. Hezel, Albert C. Koong, Andrew J. Aguirre, Brian M. Wolpin, Jonathan A. Nowak
Journal: Cancer Research
Cancer Res (2020) 80 (22_Supplement): PR-001.
https://doi.org/10.1158/1538-7445.PANCA20-PR-001
Published: 13 November 2020
View articletitled, Abstract PR-001: Neoadjuvant therapy is associated with altered composition of immune cell infiltration and an anti-tumorigenic microenvironment in resected pancreatic cancer