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Mahvash Zakikhani
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Journal Articles

Abstract 520: Therapeutic antibodies against parathyroid hormone-related peptide (PTHrP) inhibit the growth of established skeletal metastasis in mice transplanted with human triple negative breast cancer cell lines

Free
Jiarong Li, Anne Camirand, Mahvash Zakikhani, Karine Sellin, Richard Kremer
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 520.
https://doi.org/10.1158/1538-7445.AM2020-520
Published: 15 August 2020
View article titled, Abstract 520: Therapeutic antibodies against parathyroid hormone-related peptide (PTHrP) inhibit the growth of established skeletal metastasis in mice transplanted with human triple negative breast cancer cell lines
Journal Articles

Serine Deprivation Enhances Antineoplastic Activity of Biguanides

Free
Simon-Pierre Gravel, Laura Hulea, Nader Toban, Elena Birman, Marie-José Blouin, Mahvash Zakikhani, Yunhua Zhao, Ivan Topisirovic, Julie St-Pierre, Michael Pollak
Journal: Cancer Research
Cancer Res (2014) 74 (24): 7521–7533.
https://doi.org/10.1158/0008-5472.CAN-14-2643-T
Published: 14 December 2014
View article titled, Serine Deprivation Enhances Antineoplastic Activity of Biguanides
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Journal Articles

Abstract 4615: The hyperinsulinemia caused by PI3K inhibitors attenuates their antineoplastic efficacy, but can be minimized by co-administration of metformin.

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Marie-José Blouin, Elena Birman, Yunhua Zhao, Mahvash Zakikhani, Michael N. Pollak
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 4615.
https://doi.org/10.1158/1538-7445.AM2013-4615
Published: 15 April 2013
View article titled, Abstract 4615: The hyperinsulinemia caused by PI3K inhibitors attenuates their antineoplastic efficacy, but can be minimized by co-administration of metformin.
Journal Articles

Carbon Source and Myc Expression Influence the Antiproliferative Actions of Metformin

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Shiva Javeshghani, Mahvash Zakikhani, Shane Austin, Miguel Bazile, Marie-José Blouin, Ivan Topisirovic, Julie St-Pierre, Michael N. Pollak
Journal: Cancer Research
Cancer Res (2012) 72 (23): 6257–6267.
https://doi.org/10.1158/0008-5472.CAN-12-2907
Published: 29 November 2012
View article titled, Carbon Source and Myc Expression Influence the Antiproliferative Actions of Metformin
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Journal Articles

Abstract 2300: Insulin receptor kinase inhibition is better tolerated than hypoinsulinemia and more effective than metformin in treating breast cancer

Free
Carly Dool, Haider Mashhedi, Mahvash Zakikhani, Stephanie David, Yunhua Zhao, Elena Birman, Joan M. Carboni, Marco Gottardis, Marie-Jose Blouin, Michael N. Pollak
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 2300.
https://doi.org/10.1158/1538-7445.AM2011-2300
Published: 15 April 2011
View article titled, Abstract 2300: Insulin receptor kinase inhibition is better tolerated than hypoinsulinemia and more effective than metformin in treating breast cancer
Journal Articles

Abstract 65: Metformin inhibits in vivo growth of MC38 colon carcinoma in the absence of LKB1 expression

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Carolyn Algire, Lilian Amrein, Miguel Bazile, Mahvash Zakikhani, Stephanie David, Michael Pollak
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 65.
https://doi.org/10.1158/1538-7445.AM10-65
Published: 15 April 2010
View article titled, Abstract 65: Metformin inhibits in vivo growth of MC38 colon carcinoma in the absence of LKB1 expression
Journal Articles

Abstract #LB-189: Metformin diminishes the stimulatory effect of a high energy diet on colon cancer growth in vivo and is associated with reduced expression of fatty acid synthase

Free
Carolyn Algire, Mahvash Zakikhani, Michael Pollak
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): LB-189.
Published: 01 May 2009
View article titled, Abstract #LB-189: Metformin diminishes the stimulatory effect of a high energy diet on colon cancer growth in vivo and is associated with reduced expression of fatty acid synthase
Journal Articles

Insulin Receptor Isoform A and Insulin-like Growth Factor II as Additional Treatment Targets in Human Osteosarcoma

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Sofia Avnet, Laura Sciacca, Manuela Salerno, Giovanni Gancitano, Maria Francesca Cassarino, Alessandra Longhi, Mahvash Zakikhani, Joan M. Carboni, Marco Gottardis, Armando Giunti, Michael Pollak, Riccardo Vigneri, Nicola Baldini
Journal: Cancer Research
Cancer Res (2009) 69 (6): 2443–2452.
https://doi.org/10.1158/0008-5472.CAN-08-2645
Published: 17 March 2009
View article titled, Insulin Receptor Isoform A and Insulin-like Growth Factor II as Additional Treatment Targets in Human Osteosarcoma
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Journal Articles

Metformin attenuates the stimulatory effect of a high energy diet on in vivo H59 carcinoma growth

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Carolyn Algire, Mahvash Zakikhani, Marie-Jose Blouin, Jianhua Shuai, Michael Pollak
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 4349.
Published: 01 May 2008
View article titled, Metformin attenuates the stimulatory effect of a high energy diet on in vivo H59 carcinoma growth
Journal Articles

Metformin Inhibits Mammalian Target of Rapamycin–Dependent Translation Initiation in Breast Cancer Cells

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Ryan J.O. Dowling, Mahvash Zakikhani, I. George Fantus, Michael Pollak, Nahum Sonenberg
Journal: Cancer Research
Cancer Res (2007) 67 (22): 10804–10812.
https://doi.org/10.1158/0008-5472.CAN-07-2310
Published: 15 November 2007
View article titled, Metformin Inhibits Mammalian Target of Rapamycin–Dependent Translation Initiation in Breast Cancer Cells
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Journal Articles

Metformin mediated AMPK activation inhibits translation initiation in breast cancer cells

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Ryan Dowling, Mahvash Zakikhani, Nahum Sonenberg, Michael Pollak
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 4470.
Published: 01 May 2007
View article titled, Metformin mediated AMPK activation inhibits translation initiation in breast cancer cells
Journal Articles

Adiponectin and metformin inhibit prostate and colon cancer cell proliferation via AMP kinase (AMPK)- dependent mechanisms

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Mahvash Zakikhani, Michael Pollak
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 4467.
Published: 01 May 2007
View article titled, Adiponectin and metformin inhibit prostate and colon cancer cell proliferation via AMP kinase (AMPK)- dependent mechanisms
Journal Articles

Metformin Is an AMP Kinase–Dependent Growth Inhibitor for Breast Cancer Cells

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Mahvash Zakikhani, Ryan Dowling, I. George Fantus, Nahum Sonenberg, Michael Pollak
Journal: Cancer Research
Cancer Res (2006) 66 (21): 10269–10273.
https://doi.org/10.1158/0008-5472.CAN-06-1500
Published: 01 November 2006
View article titled, Metformin Is an AMP Kinase–Dependent Growth Inhibitor for Breast Cancer Cells
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Includes: Supplementary data