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Journal Articles

Abstract 3331: Highly sensitive blood-based multi-cancer screening device with tiered specificity based on diagnostic workflow

Yupeng He, Anton Valouev, Liyang Xiong, William W. Young Greenwald, Victoria M. Raymond, Sven Duenwald, AmirAli Talasaz
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 3331.
https://doi.org/10.1158/1538-7445.AM2023-3331
Published: 04 April 2023
View article titled, Abstract 3331: Highly sensitive blood-based multi-cancer screening device with tiered specificity based on diagnostic workflow
Journal Articles

Abstract PS18-28: Genomic heterogeneity and associated clinical outcomes of breast cancers treated with CDK4/6 inhibitors: Insights from real-world clinical genomic data

Junhua Yu, Christopher Ton, Enrique Marino, Naveen Kumar, Rajesh Kucharlapati, Rajesh Chavali, Gautam Nayak, David Hanna, Aaron Hardin, Victoria M Raymond, Kathryn Lang
Journal: Cancer Research
Cancer Res (2021) 81 (4_Supplement): PS18-28.
https://doi.org/10.1158/1538-7445.SABCS20-PS18-28
Published: 15 February 2021
View article titled, Abstract PS18-28: Genomic heterogeneity and associated clinical outcomes of breast cancers treated with CDK4/6 inhibitors: Insights from real-world clinical genomic data
Journal Articles

Abstract PS18-15: Real-world clinical-genomic data identifies the ESR1 clonal and subclonal circulating tumor DNA (ctDNA) landscape and provides insight into clinical outcomes

David Hanna, Jamie Hutchins, Junhua Yu, Enrique Marino, Naveen Kumar, Rajesh Kucharlapati, Rajesh Chavali, Gautam Nayak, Aaron Hardin, Stephen Fairclough, Victoria M Raymond, Kathryn Lang
Journal: Cancer Research
Cancer Res (2021) 81 (4_Supplement): PS18-15.
https://doi.org/10.1158/1538-7445.SABCS20-PS18-15
Published: 15 February 2021
View article titled, Abstract PS18-15: Real-world clinical-genomic data identifies the ESR1 clonal and subclonal circulating tumor DNA (ctDNA) landscape and provides insight into clinical outcomes
Journal Articles

Abstract OT-07-01: Guardant360® related clinical outcomes in patients who share medical records-breast cancer (GRECO-B)

Aaron Fuchs, Matthew Muia, Vicky Ho, Kristi Ashton, Naveen Kumar, Enrique Marino, Junhua Yu, Kathryn Lang, Victoria M Raymond
Journal: Cancer Research
Cancer Res (2021) 81 (4_Supplement): OT-07-01.
https://doi.org/10.1158/1538-7445.SABCS20-OT-07-01
Published: 15 February 2021
View article titled, Abstract OT-07-01: Guardant360<sup>®</sup> related clinical outcomes in patients who share medical records-breast cancer (GRECO-B)
Journal Articles

Abstract 2316: Integrated genomic and epigenomic cell-free DNA (cfDNA) analysis for the detection of early-stage colorectal cancer

Oscar Westesson, Haley Axelrod, Jason Dean, Yupeng He, Paul Sample, Elena Zotenko, Ruth McCole, Mohit Goel, Charbel Eid, Jessica Kurata, Yu Kong, Anna Hartwig, Matthew Snyder, Will Greenleaf, Victoria M. Raymond, Darya Chudova, Ariel Jaimovich, AmirAli Talasaz
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 2316.
https://doi.org/10.1158/1538-7445.AM2020-2316
Published: 15 August 2020
View article titled, Abstract 2316: Integrated genomic and epigenomic cell-free DNA (cfDNA) analysis for the detection of early-stage colorectal cancer
Journal Articles

Abstract 4421: Development of a clinical-genomic database to study tumor evolution and molecular biomarkers of drug resistance in a real-world setting

Naveen Kumar, Rajesh Kucharlapati, Aaron Hardin, Victoria M. Raymond, Stephen Fairclough, Kathryn Lang
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 4421.
https://doi.org/10.1158/1538-7445.AM2020-4421
Published: 15 August 2020
View article titled, Abstract 4421: Development of a clinical-genomic database to study tumor evolution and molecular biomarkers of drug resistance in a real-world setting
Journal Articles

Abstract 734: Monitoring of dynamic changes and clonal evolution in circulating tumor DNA from patients with IDH-mutated cholangiocarcinoma treated with IDH inhibitors

Morten Lapin, Helen J. Huang, Milind Javle, Rachna T. Shroff, Shubham Pant, Anjali Raina, Kiran Madwani, Veronica R. Holley, S. Greg Call, Richard B. Lanman, Lawrence Kwong, Funda Meric-Bernstam, Victoria M. Raymond, Filip Janku
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 734.
https://doi.org/10.1158/1538-7445.AM2020-734
Published: 15 August 2020
View article titled, Abstract 734: Monitoring of dynamic changes and clonal evolution in circulating tumor DNA from patients with IDH-mutated cholangiocarcinoma treated with IDH inhibitors
Journal Articles

Abstract 4813: Comparative activity profiling of tyrosine kinase inhibitors (TKIs) against exon 20 insertions and the wild-type form of epidermal growth factor receptor (EGFR)

Richard A. Ward, Ambra Bianco, Nicola Colclough, Darren Cross, Emanuela M. Cuomo, M. Raymond V. Finlay, Martina Fitzek, Nicolas Floc’h, Sladjana Gagrica, Beverley Hammond, Matthew J. Martin, Darren McKerrecher, Daniel J. O’Neill, Jonathan P. Orme, Paul D. Smith, Anna D. Staniszewska, Jelena Urosevic, Nicky Whalley, James W. Yates
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 4813.
https://doi.org/10.1158/1538-7445.AM2019-4813
Published: 01 July 2019
View article titled, Abstract 4813: Comparative activity profiling of tyrosine kinase inhibitors (TKIs) against exon 20 insertions and the wild-type form of epidermal growth factor receptor (EGFR)
Journal Articles

Abstract 435: Cell-free circulating tumor DNA (ctDNA) detects somatic copy number loss in homologous recombination repair genes

Catalin Barbacioru, Victoria M. Raymond, Marcin Sikora, Elena Helman, Sante Gnerre, Stephen Fairclough, Darya Chudova, Richard B. Lanman, AmirAli Talasaz
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 435.
https://doi.org/10.1158/1538-7445.AM2019-435
Published: 01 July 2019
View article titled, Abstract 435: Cell-free circulating tumor DNA (ctDNA) detects somatic copy number loss in homologous recombination repair genes
Journal Articles

Abstract 450: Novel genomic differences in cell-free circulating tumor DNA (cfDNA) profiles of early versus older onset colorectal cancer (CRC)

Afsaneh Barzi, Carin R. Espenschied, Victoria M. Raymond, Richard B. Lanman, Heinz-Josef Lenz
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 450.
https://doi.org/10.1158/1538-7445.AM2019-450
Published: 01 July 2019
View article titled, Abstract 450: Novel genomic differences in cell-free circulating tumor DNA (cfDNA) profiles of early versus older onset colorectal cancer (CRC)
Journal Articles

Abstract 4460: Clinical utility of comprehensive cell-free DNA (cfDNA) analysis to identify genomic biomarkers in newly diagnosed metastatic non-small cell lung cancer (mNSCLC)

Natasha Leighl, Ray D. Page, Victoria M. Raymond, Davey Daniel, Stephen Divers, Karen L. Reckamp, Miguel A. Villalona-Calero, Daniel Dix, Matthew Jackson, Justin I. Odegaard, Vassiliki A. Papadimitrakopoulou
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 4460.
https://doi.org/10.1158/1538-7445.AM2019-4460
Published: 01 July 2019
View article titled, Abstract 4460: Clinical utility of comprehensive cell-free DNA (cfDNA) analysis to identify genomic biomarkers in newly diagnosed metastatic non-small cell lung cancer (mNSCLC)
Journal Articles

Abstract 4451: Evaluation of the therapeutic potential of phosphine oxide pyrazole inhibitors in tumors harboring EGFR C797S mutation

Nicolas Floch, M. Raymond V. Finlay, Ambra Bianco, Sue Bickerton, Nicola Colclough, Darren A. Cross, Emanuela M. Cuomo, Carine M. Guerot, David Hargreaves, Matthew J. Martin, Darren McKerrecher, Daniel J. O’Neill, Jonathan P. Orme, Amar Rahi, Paul D. Smith, Richard A. Ward
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 4451.
https://doi.org/10.1158/1538-7445.AM2019-4451
Published: 01 July 2019
View article titled, Abstract 4451: Evaluation of the therapeutic potential of phosphine oxide pyrazole inhibitors in tumors harboring EGFR C797S mutation
Journal Articles

Abstract 916: Combined genomic and epigenomic assessment of cell-free circulating tumor DNA (ctDNA) improves assay sensitivity in early-stage colorectal cancer (CRC)

Seung-Tae Kim, Victoria M. Raymond, Joon Oh Park, Elena Zotenko, Young Suk Park, Matthew Schultz, Won Ki Kang, Oscar Westesson, Hee-Cheol Kim, Yupeng He, Justin I. Odegaard, Stefanie A. Mortimer, William J. Greenleaf, Ariel Jaimovich, Jeeyun Lee, AmirAli Talasaz
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 916.
https://doi.org/10.1158/1538-7445.AM2019-916
Published: 01 July 2019
View article titled, Abstract 916: Combined genomic and epigenomic assessment of cell-free circulating tumor DNA (ctDNA) improves assay sensitivity in early-stage colorectal cancer (CRC)
Journal Articles

Abstract 3662: Cell-free DNA sequencing demonstrates persistence of nucleic acid-based therapy—opportunities for detection and monitoring

Marcin Sikora, Alexander Artyomenko, James Strauss, Richard B. Lanman, Victoria M. Raymond, Justin Odegaard
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 3662.
https://doi.org/10.1158/1538-7445.AM2018-3662
Published: 01 July 2018
View article titled, Abstract 3662: Cell-free DNA sequencing demonstrates persistence of nucleic acid-based therapy—opportunities for detection and monitoring
Journal Articles

Abstract 936: Analysis of cell-free DNA from 32,991 advanced cancers reveals novel co-occurring activating RET alterations and oncogenic signaling pathway aberrations

Karen L. Reckamp, Thereasa A. Rich, Young Kwang Chae, Robert C. Doebele, Wade T. Iams, Michael Oh, Victoria M. Raymond, Richard B. Lanman, Thomas E. Stinchcombe, Vivek Subbiah, David R. Trevarthen, Oliver P. Gautschi
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 936.
https://doi.org/10.1158/1538-7445.AM2018-936
Published: 01 July 2018
View article titled, Abstract 936: Analysis of cell-free DNA from 32,991 advanced cancers reveals novel co-occurring activating <em>RET</em> alterations and oncogenic signaling pathway aberrations
Journal Articles

Abstract 916: A screen to target EGFR (C797S) in osimertinib-resistant lung cancer identifies brigatinib-based combinations that synergistically inhibit cell growth

Matthew J. Martin, Nicolas Floc'h, Chrysiis Michaloglou, M Raymond Finlay, Richard A. Ward, Paul D. Smith, Darren A. Cross
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 916.
https://doi.org/10.1158/1538-7445.AM2018-916
Published: 01 July 2018
View article titled, Abstract 916: A screen to target EGFR (C797S) in osimertinib-resistant lung cancer identifies brigatinib-based combinations that synergistically inhibit cell growth
Journal Articles

Abstract 2737: Development of a clinically actionable, ultra-sensitive multi-oncogene panel compatible with ctDNA testing in urine and plasma

Karena A. Kosco, Matthew Wiggin, Peter J. Croucher, David Broemeling, Shiloh Guerrero, Laura Mai, Kurt Krummel, Victoria M. Raymond, Mark G. Erlander, Andre Marziali, Karsten Schmidt
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 2737.
https://doi.org/10.1158/1538-7445.AM2017-2737
Published: 01 July 2017
View article titled, Abstract 2737: Development of a clinically actionable, ultra-sensitive multi-oncogene panel compatible with ctDNA testing in urine and plasma
Journal Articles

Abstract 2079: Osimertinib, an irreversible mutant selective EGFR tyrosine kinase inhibitor, exerts anti tumor activity in NSCLC harbouring exon 20 insertion mutant-EGFR

Nicolas Floc'h, Susan Ashton, Ambra Bianco, Nicola Colclough, Darren AE Cross, Maria Emanuela Cuomo, M. Raymond V. Finlay, Matthew J Martin, Ludovic Menard, Darren McKerrecher, Daniel J O'Neill, Jonathan P Orme, Anna D Staniszewska, Richard A Ward, James W T Yates
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 2079.
https://doi.org/10.1158/1538-7445.AM2017-2079
Published: 01 July 2017
View article titled, Abstract 2079: Osimertinib, an irreversible mutant selective EGFR tyrosine kinase inhibitor, exerts anti tumor activity in NSCLC harbouring exon 20 insertion mutant-EGFR
Journal Articles

Abstract A20: Detection and quantification of ctDNA KRAS mutations from patients with unresectable pancreatic cancer

Inna Chen, Victoria M. Raymond, Jennifer A. Geis, Sandeep Pingle, Eric A. Collisson, Vlada Melnikova, Mark G. Erlander, Julia A. Johansen, Fernando Blanco
Journal: Cancer Research
Cancer Res (2016) 76 (24_Supplement): A20.
https://doi.org/10.1158/1538-7445.PANCA16-A20
Published: 14 December 2016
View article titled, Abstract A20: Detection and quantification of ctDNA KRAS mutations from patients with unresectable pancreatic cancer
Journal Articles

Abstract 3676: Influence of early toxicology assessment on the selection of azd9291

Mark J. Anderton, Richard A. Ward, Paula Daunt, Anne Galer, Darren A. E. Cross, Louise Marks, M. Raymond V. Finlay
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 3676.
https://doi.org/10.1158/1538-7445.AM2014-3676
Published: 01 October 2014
View article titled, Abstract 3676: Influence of early toxicology assessment on the selection of azd9291