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M. Isabel Chiu
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Journal Articles

Abstract 2224: Discovery, development and characterization of a new class of therapeutic anti-PD-1 antibody

Lei Wang, Najmia Amirina, Fellix Scheuplein, Vikki Spaulding, Yanyan Wang, Sri Vadde, M. Isabel Chiu, Daniel Doty, Thomas McQuade, Bin Feng, Sheila Ranganath, Anhco “Cokey” Nguyen.
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 2224.
https://doi.org/10.1158/1538-7445.AM2016-2224
Published: 15 July 2016
View articletitled, Abstract 2224: Discovery, development and characterization of a new class of therapeutic anti-PD-1 antibody
Journal Articles

Abstract 2737: Spontaneous genomic alterations identified in a chimeric model of colorectal cancer guide effective combinatorial therapy.

Yinghui Zhou, William M. Rideout, Angela Bressel, Sireesha Yalavarthi, Tong Zi, Anthony Monti, Steve Bottega, Bin Feng, M. Isabel Chiu, Marcus Bosenberg, Joerg Heyer
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 2737.
https://doi.org/10.1158/1538-7445.AM2013-2737
Published: 15 April 2013
View articletitled, Abstract 2737: Spontaneous genomic alterations identified in a chimeric model of colorectal cancer guide effective combinatorial therapy.
Journal Articles

Abstract 1631: Tumorigenicity of IGF-1R and IR: Rationale for co-targeting IGF-1R and IR in cancer

Lorena Lerner, Qing Liu, Nianjun Tao, John Yang, Eric Brown, Susan Koujak, Brian Krieger, Lu Huang, Maryland Rosenfeld-Franklin, Mark Miglarese, Jonathan Pachter, Murray O. Robinson, M. Isabel Chiu, David Epstein, Elizabeth Buck
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 1631.
https://doi.org/10.1158/1538-7445.AM2011-1631
Published: 15 April 2011
View articletitled, Abstract 1631: Tumorigenicity of IGF-1R and IR: Rationale for co-targeting IGF-1R and IR in cancer
Journal Articles

Abstract 1727: Preclinical evaluation of pan-VEGFR inhibitor tivozanib in combination with capecitabine, sirolimus or erlotinib in genetically engineered tumor models support combinations based on complementary mechanisms

Feng Jiang, Luhua Shen, Xiaojian Sun, Guangmu Li, Angela Bressel, William M. Rideout, Yinghui Zhou, Joerg Heyer, M. Isabel Chiu, Murray O. Robinson, Jie Lin
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 1727.
https://doi.org/10.1158/1538-7445.AM2011-1727
Published: 15 April 2011
View articletitled, Abstract 1727: Preclinical evaluation of pan-VEGFR inhibitor tivozanib in combination with capecitabine, sirolimus or erlotinib in genetically engineered tumor models support combinations based on complementary mechanisms
Journal Articles

Abstract 646: Identification of FURIN as a tumor maintenance gene in solid tumors by in vivo Retroviral Mutagenesis and Directed Complementation

Lerner Lorena, Qing Liu, John Yang, Brian Krieger, Nianjun Tao, Jodi Zarycki, Fanglei You, Omar Kabbarah, Murray O. Robinson, M. Isabel Chiu
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 646.
https://doi.org/10.1158/1538-7445.AM10-646
Published: 15 April 2010
View articletitled, Abstract 646: Identification of FURIN as a tumor maintenance gene in solid tumors by in vivo Retroviral Mutagenesis and Directed Complementation
Journal Articles

Abstract 3267: Human population based engineered breast tumor model for in vivo biomarker discovery

Min Wu, Kimberly Clark, Nanhua Deng, Zuhua Cai, Megan E. Serpa, Tong Zi, Xiaojian Sun, Richard Nicoletti, Kathryn Sun, Bing Feng, Jie Lin, Joerg Heyer, M Isabel Chiu, Murray O. Robinson
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 3267.
https://doi.org/10.1158/1538-7445.AM10-3267
Published: 15 April 2010
View articletitled, Abstract 3267: Human population based engineered breast tumor model for in vivo biomarker discovery
Journal Articles

De novo Discovery of a γ-Secretase Inhibitor Response Signature Using a Novel In vivo Breast Tumor Model

James W. Watters, Chun Cheng, Pradip K. Majumder, Ruojie Wang, Sireesha Yalavarthi, Carol Meeske, Lingxin Kong, Wenping Sun, Jie Lin, Joerg Heyer, Chris Ware, Christopher Winter, John F. Reilly, Tim Demuth, Steve Clark, M. Isabel Chiu, Murray O. Robinson, Nancy Kohl, Karuppiah Kannan
Journal: Cancer Research
Cancer Res (2009) 69 (23): 8949–8957.
https://doi.org/10.1158/0008-5472.CAN-09-1544
Published: 30 November 2009
View articletitled, De novo Discovery of a γ-Secretase Inhibitor Response Signature Using a Novel In vivo Breast Tumor Model
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Includes: Supplementary data
Journal Articles

Abstract #4979: Identification of a gene signature of epithelial to mesenchymal transition

Julie Kan, Gretchen Argast, Stuart Thomson, John Haley, Richard Nicoletti, James Abraham, Matthew O'Connor, Regina Sennello, G. David Young, Maryland Rosenfeld-Franklin, Karuppiah Kannan, Joerg Heyer, M. Isabel Chiu, David Epstein, Murray Robinson
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 4979.
Published: 01 May 2009
View articletitled, Abstract #4979: Identification of a gene signature of epithelial to mesenchymal transition