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Journal Articles

Abstract PO028: Embryonic protein NODAL as a potential modulator of the tumour microenvironment: Breast cancer secretome reprogramming and fibroblast activation

Dylan Dieters-Castator, Paola M. Dantonio, Matt Piaseczny, Guihua Zhang, Jiahui Liu, Miljan Kuljanin, Stephen Sherman, Michael Jewer, Katherine Quesnel, Eun-Young Kang, Martin Köbel, Gabrielle M. Siegers, Andrew Leask, David Hess, Gilles Lajoie, Lynne-Marie Postovit

Cancer Res (2021) 81 (5_Supplement): PO028.

DOI: https://doi.org/10.1158/1538-7445.TME21-PO028

Published: 01 March 2021

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Journal Articles

MNK1/NODAL Signaling Promotes Invasive Progression of Breast Ductal Carcinoma In Situ

Cancer Res (2019) 79 (7): 1646–1657.

DOI: https://doi.org/10.1158/0008-5472.CAN-18-1602

Published: 01 April 2019

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Includes: Supplementary data

Journal Articles

Abstract 3315: Breast cancer stem cell induction by COX-2 via EP4/PI3K-AKT/NOTCH-WNT axis: EP4 as therapeutic target

Mousumi Majumder, Xiping Xin, Ling Liu, Elena Tutunea-Fatan, Mauricio Rodriguez-Torres, Krista Vincent, Andrew Deweyert, Lynne-Marie Postovit, David Hess, Peeyush K. Lala

Cancer Res (2016) 76 (14_Supplement): 3315.

DOI: https://doi.org/10.1158/1538-7445.AM2016-3315

Published: 15 July 2016

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Journal Articles

Abstract 4812: A novel EGFL7-derived peptide, E7C13, is a potent anti-tumor agent that inhibits angiogenesis in a beta 1 integrin- and thrombospondin-dependent manner

Choi-Fong Cho, Laura A. Fung, Tienabe Nsiama, Lihai Yu, Alisha Kadam, Daniela F. Quail, Katia Carmine-Simmen, Desmond Pink, Lynne-Marie Postovit, Leonard G. Luyt, John D. Lewis

Cancer Res (2014) 74 (19_Supplement): 4812.

DOI: https://doi.org/10.1158/1538-7445.AM2014-4812

Published: 01 October 2014

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Journal Articles

Abstract 3905: Stem like cells in human breast cancer: EP4 as a therapeutic target

Mousumi Majumder, Xiping Xin, Ling Liu, Gillian Bell, Erin Landman, Mauricio Rodriguez- Torres, Lynne-Marie Postovit, David Hess, Peeyush K. Lala

Cancer Res (2014) 74 (19_Supplement): 3905.

DOI: https://doi.org/10.1158/1538-7445.AM2014-3905

Published: 01 October 2014

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Journal Articles

Abstract 1315: Regulation of Nodal expression by estrogen in hormone responsive human breast cancer cell lines.

Padmalaya Das, Daniela Quail, Lynne-Marie Postovit

Cancer Res (2013) 73 (8_Supplement): 1315.

DOI: https://doi.org/10.1158/1538-7445.AM2013-1315

Published: 15 April 2013

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Journal Articles

Embryonic Protein Nodal Promotes Breast Cancer Vascularization

Daniela F. Quail, Logan A. Walsh, Guihua Zhang, Scott D. Findlay, Juan Moreno, Laura Fung, Amber Ablack, John D. Lewis, Susan J. Done, David A. Hess, Lynne-Marie Postovit

Cancer Res (2012) 72 (15): 3851–3863.

DOI: https://doi.org/10.1158/0008-5472.CAN-11-3951

Published: 31 July 2012

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Includes: Supplementary data

Journal Articles

Abstract 3257: Nodal signalling in choriocarcinoma cells

Jeffrey Law, Alice Luca, Guihua Zhang, Lynne-Marie Postovit, Moshmi Bhattacharya

Cancer Res (2012) 72 (8_Supplement): 3257.

DOI: https://doi.org/10.1158/1538-7445.AM2012-3257

Published: 15 April 2012

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Journal Articles

Abstract 3354: Investigating the role of Nodal in the regulation of integrin α6β4high trophoblast progenitor cells

Alia Cloutier-Bosworth, Peeyush K. Lala, Lynne-Marie Postovit

Cancer Res (2012) 72 (8_Supplement): 3354.

DOI: https://doi.org/10.1158/1538-7445.AM2012-3354

Published: 15 April 2012

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Journal Articles

Regulation of the Embryonic Morphogen Nodal by Notch4 Facilitates Manifestation of the Aggressive Melanoma Phenotype

Katharine M. Hardy, Dawn A. Kirschmann, Elisabeth A. Seftor, Naira V. Margaryan, Lynne-Marie Postovit, Luigi Strizzi, Mary J.C. Hendrix

Cancer Res (2010) 70 (24): 10340–10350.

DOI: https://doi.org/10.1158/0008-5472.CAN-10-0705

Published: 14 December 2010

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Includes: Supplementary data

Journal Articles

Abstract 447: Hypoxia upregulates Nodal expression via the HIF-1 pathway in poorly metastatic breast cancer cells

Meghan J. Taylor, Lynne-Marie Postovit

Cancer Res (2010) 70 (8_Supplement): 447.

DOI: https://doi.org/10.1158/1538-7445.AM10-447

Published: 15 April 2010

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Journal Articles

Abstract 5204: Nodal regulates invasive phenotypes in extravillous and choriocarcinoma trophoblast cells

Guihua Zhang, Lynne Marie Postovit

Cancer Res (2010) 70 (8_Supplement): 5204.

DOI: https://doi.org/10.1158/1538-7445.AM10-5204

Published: 15 April 2010

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Journal Articles

Abstract 2375: Nodal regulates the angiogenic switch in breast cancer

Daniela Quail, Guihua Zhang, Lynne-Marie Postovit

Cancer Res (2010) 70 (8_Supplement): 2375.

DOI: https://doi.org/10.1158/1538-7445.AM10-2375

Published: 15 April 2010

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Journal Articles

Development and Cancer: At the Crossroads of Nodal and Notch Signaling

Luigi Strizzi, Katharine M. Hardy, Elisabeth A. Seftor, Fabricio F. Costa, Dawn A. Kirschmann, Richard E.B. Seftor, Lynne-Marie Postovit, Mary J.C. Hendrix

Cancer Res (2009) 69 (18): 7131–7134.

DOI: https://doi.org/10.1158/0008-5472.CAN-09-1199

Published: 14 September 2009

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Journal Articles

Abstract #252: The role of oxygen as a regulator of Nodal expression in breast cancer

Meghan Taylor, Lynne-Marie Postovit

Cancer Res (2009) 69 (9_Supplement): 252.

Published: 01 May 2009

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Journal Articles

Abstract #3073: Nodal promotes metastatic phenotypes in breast cancer cells.

Daniela Quail, Lynne-Marie Postovit

Cancer Res (2009) 69 (9_Supplement): 3073.

Published: 01 May 2009

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Journal Articles

Reprogramming metastatic tumor cells with embryonic microenvironments: Targeting tumor cell plasticity

Mary Hendrix, Elisabeth Seftor, Richard Seftor, Naira Margaryan, Jolanta Topczewska, Brian Nickoloff, Jacek Topczewski, Jennifer Kasemeier-Kulesa, Paul Kulesa, Lynne-Marie Postovit

Cancer Res (2007) 67 (9_Supplement): SY10-01.

Published: 01 May 2007

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Journal Articles

Epigenetic analysis of NODAL in multipotent tumor cells and embryonic stem cells

Fabricio Costa, Lynne-Marie Postovit, Jared Bischof, Sergey Malchenko, Elizabeth Seftor, Richard Seftor, Maria de Fatima Bonaldo, Marcelo Soares, Mary Hendrix

Cancer Res (2007) 67 (9_Supplement): 261.

Published: 01 May 2007

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Journal Articles

Influence of the Microenvironment on Melanoma Cell Fate Determination and Phenotype

Lynne-Marie Postovit, Elisabeth A. Seftor, Richard E.B. Seftor, Mary J.C. Hendrix

Cancer Res (2006) 66 (16): 7833–7836.

DOI: https://doi.org/10.1158/0008-5472.CAN-06-0731

Published: 15 August 2006

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Journal Articles

Focal Adhesion Kinase Promotes the Aggressive Melanoma Phenotype

Angela R. Hess, Lynne-Marie Postovit, Naira V. Margaryan, Elisabeth A. Seftor, Galen B. Schneider, Richard E.B. Seftor, Brian J. Nickoloff, Mary J.C. Hendrix

Cancer Res (2005) 65 (21): 9851–9860.

DOI: https://doi.org/10.1158/0008-5472.CAN-05-2172

Published: 01 November 2005

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Includes: Supplementary data

NARROW

Abstract PO028: Embryonic protein NODAL as a potential modulator of the tumour microenvironment: Breast cancer secretome reprogramming and fibroblast activation

MNK1/NODAL Signaling Promotes Invasive Progression of Breast Ductal Carcinoma In Situ

Abstract 3315: Breast cancer stem cell induction by COX-2 via EP4/PI3K-AKT/NOTCH-WNT axis: EP4 as therapeutic target

Abstract 4812: A novel EGFL7-derived peptide, E7C13, is a potent anti-tumor agent that inhibits angiogenesis in a beta 1 integrin- and thrombospondin-dependent manner

Abstract 3905: Stem like cells in human breast cancer: EP4 as a therapeutic target

Abstract 1315: Regulation of Nodal expression by estrogen in hormone responsive human breast cancer cell lines.

Embryonic Protein Nodal Promotes Breast Cancer Vascularization

Abstract 3257: Nodal signalling in choriocarcinoma cells

Abstract 3354: Investigating the role of Nodal in the regulation of integrin α6β4high trophoblast progenitor cells

Regulation of the Embryonic Morphogen Nodal by Notch4 Facilitates Manifestation of the Aggressive Melanoma Phenotype

Abstract 447: Hypoxia upregulates Nodal expression via the HIF-1 pathway in poorly metastatic breast cancer cells

Abstract 5204: Nodal regulates invasive phenotypes in extravillous and choriocarcinoma trophoblast cells

Abstract 2375: Nodal regulates the angiogenic switch in breast cancer

Development and Cancer: At the Crossroads of Nodal and Notch Signaling

Abstract #252: The role of oxygen as a regulator of Nodal expression in breast cancer

Abstract #3073: Nodal promotes metastatic phenotypes in breast cancer cells.

Reprogramming metastatic tumor cells with embryonic microenvironments: Targeting tumor cell plasticity

Epigenetic analysis of NODAL in multipotent tumor cells and embryonic stem cells

Influence of the Microenvironment on Melanoma Cell Fate Determination and Phenotype

Focal Adhesion Kinase Promotes the Aggressive Melanoma Phenotype

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