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Lynn Moscinski
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Journal Articles

Abstract PR008: Cell state transitions drive the evolution of disease progression in B-cell acute lymphoblastic leukemia

Free
Curtis Gravenmier, Ling Zhang, Lynn Moscinski, Jeffrey West
Journal: Cancer Research
Cancer Res (2024) 84 (3_Supplement_2): PR008.
https://doi.org/10.1158/1538-7445.CANEVOL23-PR008
Published: 01 February 2024
View articletitled, Abstract PR008: Cell state transitions drive the evolution of disease progression in B-cell acute lymphoblastic leukemia
Journal Articles

Abstract 4944: Combined treatment of BTK and PI3K inhibitors synergistically disrupts BCR-signaling, overcomes microenviroment-mediated survival and drug resistance in mantle cell lymphoma.

Free
Jiangchuan Tao, Tint Lwin, Xiaohong Zhao, Bijal Shah, Ling Zhang, Lynn Moscinski, William Dalton, Eduardo M. Sotomayor, Jianguo Tao
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 4944.
https://doi.org/10.1158/1538-7445.AM2013-4944
Published: 15 April 2013
View articletitled, Abstract 4944: Combined treatment of BTK and PI3K inhibitors synergistically disrupts BCR-signaling, overcomes microenviroment-mediated survival and drug resistance in mantle cell lymphoma.
Journal Articles

Abstract 2097: microRNA profile and identification of miR-29 as a prognostic marker and pathogenetic factor by targeting CDK6 in mantle cell lymphoma

Free
Jian-jun Zhao, Jianhong Lin, Tint Lwin, Hua Yang, Jianping Guo, William Kong, Sophie Dessureault, Lynn Moscinski, Dorna Rezania, William S. Dalton, Eduardo Sotomayor, Jianguo Tao, Jin Q. Cheng
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 2097.
https://doi.org/10.1158/1538-7445.AM10-2097
Published: 15 April 2010
View articletitled, Abstract 2097: microRNA profile and identification of miR-29 as a prognostic marker and pathogenetic factor by targeting CDK6 in mantle cell lymphoma
Journal Articles

Abstract #4302: TGF\#946;-mediated growth inhibition of human myeloid leukemia cells is p53-p21 pathway independent

Free
Alessandra Angelini, Anjali Ramkissoon, Shakima St. Clair, Lynn Moscinski, Xiaotang Hu
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 4302.
Published: 01 May 2009
View articletitled, Abstract #4302: TGF\#946;-mediated growth inhibition of human myeloid leukemia cells is p53-p21 pathway independent
Journal Articles

Bone marrow stromal cells protect non-Hodgkin’s B lymphoma cells from apoptosis through B cell-activating factor of the TNF family (BAFF)

Free
Tint Lwin, Amy Wu, Luis Crespo, Sophie Dessureault, Lynn Moscinski, Eduardo Sotomayor, Dalton William, Jianguo Tao
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 5524.
Published: 01 May 2008
View articletitled, Bone marrow stromal cells protect non-Hodgkin’s B lymphoma cells from apoptosis through B cell-activating factor of the TNF family (BAFF)
Journal Articles

Cotreatment with 17-Allylamino-Demethoxygeldanamycin and FLT-3 Kinase Inhibitor PKC412 Is Highly Effective against Human Acute Myelogenous Leukemia Cells with Mutant FLT-3

Free
Prince George, Purva Bali, Pamela Cohen, Jianguo Tao, Fei Guo, Celia Sigua, Anasuya Vishvanath, Warren Fiskus, Anna Scuto, Srinivas Annavarapu, Lynn Moscinski, Kapil Bhalla
Journal: Cancer Research
Cancer Res (2004) 64 (10): 3645–3652.
https://doi.org/10.1158/0008-5472.CAN-04-0006
Published: 17 May 2004
View articletitled, Cotreatment with 17-Allylamino-Demethoxygeldanamycin and FLT-3 Kinase Inhibitor PKC412 Is Highly Effective against Human Acute Myelogenous Leukemia Cells with Mutant FLT-3
Open the PDF for Cotreatment with 17-Allylamino-Demethoxygeldanamycin and FLT-3 Kinase Inhibitor PKC412 Is Highly Effective against Human Acute Myelogenous Leukemia Cells with Mutant FLT-3 in another window
Journal Articles

A combination of histone deacetylase inhibitor LBH589 and the hsp90 inhibitor 17-AAG is highly active against human CML-BC and AML cells with constitutively active mutant FLT-3 tyrosine kinase.

Free
Ravi Gutti, Prince George, Purva Bali, Jianguo Tao, Fei Guo, Celia Sigua, Yunqing Li, Lynn Moscinski, Peter Atadja, Kapil N. Bhalla
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 699.
Published: 01 April 2004
View articletitled, A combination of histone deacetylase inhibitor LBH589 and the hsp90 inhibitor 17-AAG is highly active against human CML-BC and AML cells with constitutively active mutant FLT-3 tyrosine kinase.
Journal Articles

Bone marrow stromal cells prevent apoptosis of lymphoma cells by up-regulation of anti-apoptotic proteins via activation of NF-κB

Free
Tint Lwin, Lori A. Hazlehurst, Zhiwei Li, Lynn Moscinski, William S. Dalton, Jianguo Tao
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 276.
Published: 01 April 2004
View articletitled, Bone marrow stromal cells prevent apoptosis of lymphoma cells by up-regulation of anti-apoptotic proteins via activation of NF-κB
Journal Articles

Cotreatment with Histone Deacetylase Inhibitor LAQ824 Enhances Apo-2L/Tumor Necrosis Factor-Related Apoptosis Inducing Ligand-Induced Death Inducing Signaling Complex Activity and Apoptosis of Human Acute Leukemia Cells

Free
Fei Guo, Celia Sigua, Jianguo Tao, Purva Bali, Prince George, Yunqing Li, Sylvie Wittmann, Lynn Moscinski, Peter Atadja, Kapil Bhalla
Journal: Cancer Research
Cancer Res (2004) 64 (7): 2580–2589.
https://doi.org/10.1158/0008-5472.CAN-03-2629
Published: 01 April 2004
View articletitled, Cotreatment with Histone Deacetylase Inhibitor LAQ824 Enhances Apo-2L/Tumor Necrosis Factor-Related Apoptosis Inducing Ligand-Induced Death Inducing Signaling Complex Activity and Apoptosis of Human Acute Leukemia Cells
Open the PDF for Cotreatment with Histone Deacetylase Inhibitor LAQ824 Enhances Apo-2L/Tumor Necrosis Factor-Related Apoptosis Inducing Ligand-Induced Death Inducing Signaling Complex Activity and Apoptosis of Human Acute Leukemia Cells in another window
Journal Articles

Genotypic and Phenotypic Comparisons of de Novo and Acquired Melphalan Resistance in an Isogenic Multiple Myeloma Cell Line Model

Free
Lori A. Hazlehurst, Steven A. Enkemann, Craig A. Beam, Raul F. Argilagos, Jeffrey Painter, Kenneth H. Shain, Sara Saporta, David Boulware, Lynn Moscinski, Melissa Alsina, William S. Dalton
Journal: Cancer Research
Cancer Res (2003) 63 (22): 7900–7906.
Published: 21 November 2003
View articletitled, Genotypic and Phenotypic Comparisons of de Novo and Acquired Melphalan Resistance in an Isogenic Multiple Myeloma Cell Line Model
Open the PDF for Genotypic and Phenotypic Comparisons of de Novo and Acquired Melphalan Resistance in an Isogenic Multiple Myeloma Cell Line Model in another window
Journal Articles

Histone Deacetylase Inhibitor LAQ824 Both Lowers Expression and Promotes Proteasomal Degradation of Bcr-Abl and Induces Apoptosis of Imatinib Mesylate-sensitive or -refractory Chronic Myelogenous Leukemia-Blast Crisis Cells

Free
Ramadevi Nimmanapalli, Lianne Fuino, Purva Bali, Maura Gasparetto, Michele Glozak, Jianguo Tao, Lynn Moscinski, Clayton Smith, Jie Wu, Richard Jove, Peter Atadja, Kapil Bhalla
Journal: Cancer Research
Cancer Res (2003) 63 (16): 5126–5135.
Published: 26 August 2003
View articletitled, Histone Deacetylase Inhibitor LAQ824 Both Lowers Expression and Promotes Proteasomal Degradation of Bcr-Abl and Induces Apoptosis of Imatinib Mesylate-sensitive or -refractory Chronic Myelogenous Leukemia-Blast Crisis Cells
Open the PDF for Histone Deacetylase Inhibitor LAQ824 Both Lowers Expression and Promotes Proteasomal Degradation of Bcr-Abl and Induces Apoptosis of Imatinib Mesylate-sensitive or -refractory Chronic Myelogenous Leukemia-Blast Crisis Cells in another window