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Lynn E. Heasley
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Journal Articles

EGFR Mediates Responses to Small-Molecule Drugs Targeting Oncogenic Fusion Kinases

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Aria Vaishnavi, Laura Schubert, Uwe Rix, Lindsay A. Marek, Anh T. Le, Stephen B. Keysar, Magdalena J. Glogowska, Matthew A. Smith, Severine Kako, Natalia J. Sumi, Kurtis D. Davies, Kathryn E. Ware, Marileila Varella-Garcia, Eric B. Haura, Antonio Jimeno, Lynn E. Heasley, Dara L. Aisner, Robert C. Doebele
Journal: Cancer Research
Cancer Res (2017) 77 (13): 3551–3563.
https://doi.org/10.1158/0008-5472.CAN-17-0109
Published: 02 July 2017
View articletitled, EGFR Mediates Responses to Small-Molecule Drugs Targeting Oncogenic Fusion Kinases
Open the PDF for EGFR Mediates Responses to Small-Molecule Drugs Targeting Oncogenic Fusion Kinases in another window
Includes: Supplementary data
Journal Articles

Kinome RNAi Screens Reveal Synergistic Targeting of MTOR and FGFR1 Pathways for Treatment of Lung Cancer and HNSCC

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Katherine R. Singleton, Trista K. Hinz, Emily K. Kleczko, Lindsay A. Marek, Jeff Kwak, Taylor Harp, Jihye Kim, Aik Choon Tan, Lynn E. Heasley
Journal: Cancer Research
Cancer Res (2015) 75 (20): 4398–4406.
https://doi.org/10.1158/0008-5472.CAN-15-0509
Published: 14 October 2015
View articletitled, Kinome RNAi Screens Reveal Synergistic Targeting of MTOR and FGFR1 Pathways for Treatment of Lung Cancer and HNSCC
Open the PDF for Kinome RNAi Screens Reveal Synergistic Targeting of MTOR and FGFR1 Pathways for Treatment of Lung Cancer and HNSCC in another window
Includes: Supplementary data
Journal Articles

Abstract 3387: Tyrosine kinase inhibitors induce TGF-β2 expression in head and neck squamous cell carcinoma cell lines as a mechanism of acquired resistance.

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Emily K. Kleczko, Lydia R. Heasley, Marianne E. Marshall, Katherine R. Singleton, Lynn E. Heasley
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 3387.
https://doi.org/10.1158/1538-7445.AM2013-3387
Published: 15 April 2013
View articletitled, Abstract 3387: Tyrosine kinase inhibitors induce TGF-β2 expression in head and neck squamous cell carcinoma cell lines as a mechanism of acquired resistance.
Journal Articles

Abstract 5594: ALK-driven lung cancer: Potential therapeutic strategies for treatment and prevention of drug resistance

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Amanda B. Pilling, Anh T. Le, Aik-Choon Tan, Jihye Kim, Katherine R. Singleton, Lynn E. Heasley, Barbara Helfrich, James DeGregori, Robert C. Doebele
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 5594.
https://doi.org/10.1158/1538-7445.AM2012-5594
Published: 15 April 2012
View articletitled, Abstract 5594: ALK-driven lung cancer: Potential therapeutic strategies for treatment and prevention of drug resistance
Journal Articles

Protein Kinase C δ Is a Downstream Effector of Oncogenic K-ras in Lung Tumors

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Jennifer M. Symonds, Angela M. Ohm, Cristan J. Carter, Lynn E. Heasley, Theresa A. Boyle, Wilbur A. Franklin, Mary E. Reyland
Journal: Cancer Research
Cancer Res (2011) 71 (6): 2087–2097.
https://doi.org/10.1158/0008-5472.CAN-10-1511
Published: 14 March 2011
View articletitled, Protein Kinase C δ Is a Downstream Effector of Oncogenic K-ras in Lung Tumors
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Includes: Supplementary data
Journal Articles

Loss of C-Jun N-terminal kinase (JNK) 1 or 2 delays normal mammary gland involution and lengthens mammary tumor latency in the MMTV-middle T antigen mouse model

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Peter M. Marietta, Lynn E. Heasley, Carla L. Van Den Berg
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 257.
Published: 01 May 2005
View articletitled, Loss of C-Jun N-terminal kinase (JNK) 1 or 2 delays normal mammary gland involution and lengthens mammary tumor latency in the MMTV-middle T antigen mouse model
Journal Articles

Synergistic Effects of New Chemopreventive Agents and Conventional Cytotoxic Agents against Human Lung Cancer Cell Lines

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Ariel F. Soriano, Barbara Helfrich, Daniel C. Chan, Lynn E. Heasley, Paul A. Bunn, Jr., Ting-Chao Chou
Journal: Cancer Research
Cancer Res (1999) 59 (24): 6178–6184.
Published: 15 December 1999
View articletitled, Synergistic Effects of New Chemopreventive Agents and Conventional Cytotoxic Agents against Human Lung Cancer Cell Lines
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Journal Articles

Expression of Catalytically Inactive Phospholipase Cβ Disrupts Phospholipase Cβ and Mitogen-activated Protein Kinase Signaling and Inhibits Small Cell Lung Cancer Growth

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Andrew Beekman, Barbara Helfrich, Paul A. Bunn, Jr., Lynn E. Heasley
Journal: Cancer Research
Cancer Res (1998) 58 (5): 910–913.
Published: 01 March 1998
View articletitled, Expression of Catalytically Inactive Phospholipase Cβ Disrupts Phospholipase Cβ and Mitogen-activated Protein Kinase Signaling and Inhibits Small Cell Lung Cancer Growth
Open the PDF for Expression of Catalytically Inactive Phospholipase Cβ Disrupts Phospholipase Cβ and Mitogen-activated Protein Kinase Signaling and Inhibits Small Cell Lung Cancer Growth in another window