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Journal Articles

Inhibition of EGFR Overcomes Acquired Lenvatinib Resistance Driven by STAT3–ABCB1 Signaling in Hepatocellular Carcinoma

Beiyuan Hu, Tiantian Zou, Wei Qin, Xiaotian Shen, Yinghan Su, Jianhua Li, Yang Chen, Ze Zhang, Haoting Sun, Yan Zheng, Chao-Qun Wang, Zhengxin Wang, Tian-En Li, Shun Wang, Le Zhu, Xufeng Wang, Yan Fu, Xudong Ren, Qiongzhu Dong, Lun-Xiu Qin
Journal: Cancer Research
Cancer Res (2022) 82 (20): 3845–3857.
https://doi.org/10.1158/0008-5472.CAN-21-4140
Published: 17 October 2022
View articletitled, Inhibition of EGFR Overcomes Acquired Lenvatinib Resistance Driven by STAT3–ABCB1 Signaling in Hepatocellular Carcinoma
Open the PDF for Inhibition of EGFR Overcomes Acquired Lenvatinib Resistance Driven by STAT3–ABCB1 Signaling in Hepatocellular Carcinoma in another window
Includes: Supplementary data
Journal Articles

Genome-Wide RNAi Screen Identifies PMPCB as a Therapeutic Vulnerability in EpCAM+ Hepatocellular Carcinoma

Atsushi Takai, Hien Dang, Naoki Oishi, Subreen Khatib, Sean P. Martin, Dana A. Dominguez, Ji Luo, Rachel Bagni, Xiaolin Wu, Katie Powell, Qing-Hai Ye, Hu-Liang Jia, Lun-Xiu Qin, Jinqiu Chen, Gary A. Mitchell, Xiaoling Luo, Snorri S. Thorgeirsson, Xin Wei Wang
Journal: Cancer Research
Cancer Res (2019) 79 (9): 2379–2391.
https://doi.org/10.1158/0008-5472.CAN-18-3015
Published: 01 May 2019
View articletitled, Genome-Wide RNAi Screen Identifies PMPCB as a Therapeutic Vulnerability in EpCAM+ Hepatocellular Carcinoma
Open the PDF for Genome-Wide RNAi Screen Identifies PMPCB as a Therapeutic Vulnerability in EpCAM+ Hepatocellular Carcinoma in another window
Includes: Supplementary data
Journal Articles

Abstract A25: Array‐based comparative genomic hybridization of hepatocellular carcinoma reveals a unique genomic aberration pattern in tumors with poor prognosis

Stephanie Roessler, Lori Long, Anuradha Budhu, Yidong Chen, Xuelian Zhao, Robert Walker, Hu‐Liang Jia, Qing‐Hai Ye, Lun‐Xiu Qin, Zhao‐You Tang, Kent Hunter, Snorri Thorgeirsson, Paul Meltzer, Xin Wang
Journal: Cancer Research
Cancer Res (2009) 69 (23_Supplement): A25.
https://doi.org/10.1158/0008-5472.FBCR09-A25
Published: 28 October 2014
View articletitled, Abstract A25: Array‐based comparative genomic hybridization of hepatocellular carcinoma reveals a unique genomic aberration pattern in tumors with poor prognosis
Journal Articles

Abstract 5183: Modulation of miR-29 expression by alpha-fetoprotein is linked to the hepatocellular carcinoma epigenome

Sonya T. Parpart, Stephanie Roessler, Fei Dong, Vinay Rao, Junfang Ji, Lun–Xiu Qin, Qing–Hai Ye, Zhao–You Tang, Hu–Liang Jia, Xin Wei Wang
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 5183.
https://doi.org/10.1158/1538-7445.AM2014-5183
Published: 01 October 2014
View articletitled, Abstract 5183: Modulation of miR-29 expression by alpha-fetoprotein is linked to the hepatocellular carcinoma epigenome
Journal Articles

Abstract 2695: Osteopontin regulated epithelial-mesenchymal transition via PI3K/AKT signaling pathway in hepatocellular carcinoma.

Qiongzhu Dong, Xu-Chao Zhu, Chun Dai, Xiao-Fei Zhang, Hu-Liang Jia, Qing-Hai Ye, Lun-Xiu Qin
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 2695.
https://doi.org/10.1158/1538-7445.AM2013-2695
Published: 15 April 2013
View articletitled, Abstract 2695: Osteopontin regulated epithelial-mesenchymal transition via PI3K/AKT signaling pathway in hepatocellular carcinoma.
Journal Articles

Abstract 718: microRNA-29a* is a predictor for early recurrence hepatitis B virus-related hepatocellular carcinoma after surgical resection

Hai-Tao Zhu, Qiong-Zhu Dong, Yuan-Yuan Sheng, Jin-Wang Wei, Guan Wang, Hai-Jun Zhou, Ning Ren, Hu-Liang Jia, Qing-Hai Ye, Lun-Xiu Qin
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 718.
https://doi.org/10.1158/1538-7445.AM2012-718
Published: 15 April 2012
View articletitled, Abstract 718: microRNA-29a* is a predictor for early recurrence hepatitis B virus-related hepatocellular carcinoma after surgical resection
Journal Articles

Abstract 1058: Mutations in isocitrate dehydrogenase 1 and 2 are associated with DNA hypermethylation in intrahepatic cholangiocarcinomas

Pu Wang, Qiong-Zhu Dong, Chong Zhang, Pei-Fen Kuan, Yufeng Liu, William R. Jeck, Jesper B. Andersen, James Todd Auman, Janelle M. Hoskins, Jin Woo Kim, Kristian Cibulskis, Gad Getz, Heike V. Hunt, Snorri S. Thorgeirsson, Lewis R. Roberts, Dan Ye, Kun-Liang Guan, Yue Xiong, Lun-Xiu Qin, Derek Y. Chiang
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 1058.
https://doi.org/10.1158/1538-7445.AM2012-1058
Published: 15 April 2012
View articletitled, Abstract 1058: Mutations in isocitrate dehydrogenase 1 and 2 are associated with DNA hypermethylation in intrahepatic cholangiocarcinomas
Journal Articles

Association of Specific Genotypes in Metastatic Suppressor HTPAP with Tumor Metastasis and Clinical Prognosis in Hepatocellular Carcinoma

Ning Ren, Jin-Cai Wu, Qiong-Zhu Dong, Hai-Jing Sun, Hu-Liang Jia, Guo-Cai Li, Bing-Sheng Sun, Chun Dai, Jiong Shi, Jin-Wang Wei, Yuan-Yuan Sheng, Hai-Jun Zhou, Qing-Hai Ye, Lun-Xiu Qin
Journal: Cancer Research
Cancer Res (2011) 71 (9): 3278–3286.
https://doi.org/10.1158/0008-5472.CAN-10-3100
Published: 29 April 2011
View articletitled, Association of Specific Genotypes in Metastatic Suppressor HTPAP with Tumor Metastasis and Clinical Prognosis in Hepatocellular Carcinoma
Open the PDF for Association of Specific Genotypes in Metastatic Suppressor HTPAP with Tumor Metastasis and Clinical Prognosis in Hepatocellular Carcinoma in another window
Includes: Supplementary data
Journal Articles

A Unique Metastasis Gene Signature Enables Prediction of Tumor Relapse in Early-Stage Hepatocellular Carcinoma Patients

Stephanie Roessler, Hu-Liang Jia, Anuradha Budhu, Marshonna Forgues, Qing-Hai Ye, Ju-Seog Lee, Snorri S. Thorgeirsson, Zhongtang Sun, Zhao-You Tang, Lun-Xiu Qin, Xin Wei Wang
Journal: Cancer Research
Cancer Res (2010) 70 (24): 10202–10212.
https://doi.org/10.1158/0008-5472.CAN-10-2607
Published: 14 December 2010
View articletitled, A Unique Metastasis Gene Signature Enables Prediction of Tumor Relapse in Early-Stage Hepatocellular Carcinoma Patients
Open the PDF for A Unique Metastasis Gene Signature Enables Prediction of Tumor Relapse in Early-Stage Hepatocellular Carcinoma Patients in another window
Includes: Supplementary data
Journal Articles

Abstract 4818: Validation and clinical utility of a human hepatocellular carcinoma metastasis signature as prognostic classifier

Stephanie K. Roessler, Hu-Liang Jia, Anuradha S. Budhu, Lun-Xiu Qin, Qing-Hai Ye, Snorri Thorgeirsson, Zhao-You Tang, Xin W. Wang
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 4818.
https://doi.org/10.1158/1538-7445.AM10-4818
Published: 15 April 2010
View articletitled, Abstract 4818: Validation and clinical utility of a human hepatocellular carcinoma metastasis signature as prognostic classifier
Journal Articles

Abstract #1948: Bolstering hepatic cancer stem cells by wnt/\#946;-catenin signaling

Taro Yamashita, Junfang Ji, Anuradha Budhu, Marshonna Forgues, Huliang Jia, Qinghai Ye, Lun-Xiu Qin, Elaine Wauthier, Lola Reid, Hiroshi Minato, Masao Honda, Shuichi Kaneko, Wen Yang, Hongyang Wang, Zhao-You Tang, Xin Wang
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 1948.
Published: 01 May 2009
View articletitled, Abstract #1948: Bolstering hepatic cancer stem cells by wnt/\#946;-catenin signaling
Journal Articles

Abstract #4026: Human hepatocellular carcinoma tumor-derived endothelial cells present increased angiogenesis capability and drug resistance compared with normal endothelial cells

Sun Hui-Chuan, Yu-Quan Xiong, Wei Zhang, Xiao-Dong Zhu, Peng-Yuan Zhuang, Ju-Bo Zhang, Lu Wang, Wei-Zhong Wu, Lun-Xiu Qin, Zhao-You Tang
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 4026.
Published: 01 May 2009
View articletitled, Abstract #4026: Human hepatocellular carcinoma tumor-derived endothelial cells present increased angiogenesis capability and drug resistance compared with normal endothelial cells
Journal Articles

Array-CGH reveals a unique genomic aberration pattern in hepatocellular carcinoma with hepatic stem cell-like phenotype

Stephanie Roessler, Ezhou Lori Long, Yidong Chen, Taro Yamashita, Anuradha Budhu, Robert Walker, Qing-Hai Ye, Hu-Liang Jia, Lun-Xiu Qin, Zhao-You Tang, Paul Meltzer, Xin Wei Wang
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 1680.
Published: 01 May 2008
View articletitled, Array-CGH reveals a unique genomic aberration pattern in hepatocellular carcinoma with hepatic stem cell-like phenotype
Journal Articles

Knock-down of osteopontin expression through lentiviral-mediated RNA interference suppresses the proliferation and invasiveness of hepatocellular carcinoma

Bing-Sheng Sun, Qing-Hai Ye, Hai-Jing Sun, Hai-Jun Zhou, Hu-Liang Jia, Ning Ren, Lun-Xiu Qin
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 1961.
Published: 01 May 2008
View articletitled, Knock-down of osteopontin expression through lentiviral-mediated RNA interference suppresses the proliferation and invasiveness of hepatocellular carcinoma
Journal Articles

EpCAM and α-Fetoprotein Expression Defines Novel Prognostic Subtypes of Hepatocellular Carcinoma

Taro Yamashita, Marshonna Forgues, Wei Wang, Jin Woo Kim, Qinghai Ye, Huliang Jia, Anuradha Budhu, Krista A. Zanetti, Yidong Chen, Lun-Xiu Qin, Zhao-You Tang, Xin Wei Wang
Journal: Cancer Research
Cancer Res (2008) 68 (5): 1451–1461.
https://doi.org/10.1158/0008-5472.CAN-07-6013
Published: 03 March 2008
View articletitled, EpCAM and α-Fetoprotein Expression Defines Novel Prognostic Subtypes of Hepatocellular Carcinoma
Open the PDF for EpCAM and α-Fetoprotein Expression Defines Novel Prognostic Subtypes of Hepatocellular Carcinoma in another window
Includes: Supplementary data
Journal Articles

Novel prognostic subtypes of hepatocellular carcinoma with features of progenitor cells linked to wnt-β-catenin activation

Taro Yamashita, Marshonna Forgues, Wei Wang, Jin Woo Kim, Qinghai Ye, Huliang Jia, Anuradha Budhu, Vivian Takafuji, Krista Zanetti, Yidong Chen, Lun-Xiu Qin, Zhao-You Tang, Xin Wang
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 1262.
Published: 01 May 2007
View articletitled, Novel prognostic subtypes of hepatocellular carcinoma with features of progenitor cells linked to wnt-β-catenin activation
Journal Articles

Prediction of metastatic potential, recurrence and prognosis in hepatocellular carcinoma based on a unique immune response signature of the liver microenvironment

Anuradha S. Budhu, Marshonna Forgues, Qing-Hai Ye, Hu-Liang Jia, Ping He, Krista Zanetti, Udai Kammula, Yidong Chen, Lun-Xiu Qin, Zhao-You Tang, Xin Wang
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 349.
Published: 15 April 2006
View articletitled, Prediction of metastatic potential, recurrence and prognosis in hepatocellular carcinoma based on a unique immune response signature of the liver microenvironment
Journal Articles

The inhibitory effect of osteopontin down-regulated by siRNA on the invasion of human hepartocellular carcinoma cells

Lun-Xiu Qin, Xiao-Qun Zhu, Qing-Hai Ye, Yin-Kun Liu, Zhao-You Tang
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 806.
Published: 15 April 2006
View articletitled, The inhibitory effect of osteopontin down-regulated by siRNA on the invasion of human hepartocellular carcinoma cells
Journal Articles

The Association of Chromosome 8p Deletion and Tumor Metastasis in Human Hepatocellular Carcinoma

Lun-Xiu Qin, Zhao-You Tang, Jonathan S. T. Sham, Zeng-Chen Ma, Sheng-Long Ye, Xin-Da Zhou, Zhi-Quan Wu, Jeffrey M. Trent, Xin-Yuan Guan
Journal: Cancer Research
Cancer Res (1999) 59 (22): 5662–5665.
Published: 01 November 1999
View articletitled, The Association of Chromosome 8p Deletion and Tumor Metastasis in Human Hepatocellular Carcinoma
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