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Journal Articles

Targeting STAT5 or STAT5-Regulated Pathways Suppresses Leukemogenesis of Ph+ Acute Lymphoblastic Leukemia

Valentina Minieri, Marco De Dominici, Patrizia Porazzi, Samanta A. Mariani, Orietta Spinelli, Alessandro Rambaldi, Luke F. Peterson, Pierluigi Porcu, Marja T. Nevalainen, Bruno Calabretta

Cancer Res (2018) 78 (20): 5793–5807.

https://doi.org/10.1158/0008-5472.CAN-18-0195

Published: 15 October 2018

View articletitled, Targeting STAT5 or STAT5-Regulated Pathways Suppresses Leukemogenesis of Ph+ Acute Lymphoblastic Leukemia

Includes: Supplementary data

Journal Articles

Targeting CDK6 and BCL2 Exploits the “MYB Addiction” of Ph⁺ Acute Lymphoblastic Leukemia

Marco De Dominici, Patrizia Porazzi, Angela Rachele Soliera, Samanta A. Mariani, Sankar Addya, Paolo Fortina, Luke F. Peterson, Orietta Spinelli, Alessandro Rambaldi, Giovanni Martinelli, Anna Ferrari, Ilaria Iacobucci, Bruno Calabretta

Cancer Res (2018) 78 (4): 1097–1109.

https://doi.org/10.1158/0008-5472.CAN-17-2644

Published: 14 February 2018

View articletitled, Targeting CDK6 and BCL2 Exploits the “MYB Addiction” of Ph+ Acute Lymphoblastic Leukemia

Includes: Supplementary data

Journal Articles

Abstract 5083: A novel and highly efficacious small-molecule degrader of BET-BRD proteins for the treatment of acute leukemia

Ester Fernandez-Salas, Zhuo Chen, Mei Lin, Bing Zhou, Donna McEachern, Sally Przybranowski, Karson Kump, Luke F. Peterson, Malathi Kandarpa, Jiantao Hu, Fuming Xu, Liu Liu, Longchuan Bai, Bo Wen, Duxin Sun, Moshe Talpaz, Shaomeng Wang

Cancer Res (2017) 77 (13_Supplement): 5083.

https://doi.org/10.1158/1538-7445.AM2017-5083

Published: 01 July 2017

View articletitled, Abstract 5083: A novel and highly efficacious small-molecule degrader of BET-BRD proteins for the treatment of acute leukemia

Journal Articles

Abstract 2881: Deubiquitinase Usp9x controls tumorigenicity through regulation of the Ets-1 transcription factor in melanoma

Harish Potu, Luke F. Peterson Peterson, Malathi Kandarpa Kandarpa, Anupama Pal Pal, Hanshi Sun Sun, Paul W. Harms Harms, Peter C. Hollenhorst Hollenhorst, Ugur Eskiocak Eskiocak, Moshe Talpaz Talpaz, Nicholas J. Donato Donato

Cancer Res (2016) 76 (14_Supplement): 2881.

https://doi.org/10.1158/1538-7445.AM2016-2881

Published: 15 July 2016

View articletitled, Abstract 2881: Deubiquitinase Usp9x controls tumorigenicity through regulation of the Ets-1 transcription factor in melanoma

Journal Articles

Abstract 3621: Deubiquitination of AXIN1 by USP9X promotes apoptosis in melanoma in response to BRAF or MEK inhibition

Harish Potu, Luke F. Peterson, Malathi Kandarpa, Eric Fearon, Moshe Talpaz, Nicholas J. Donato

Cancer Res (2015) 75 (15_Supplement): 3621.

https://doi.org/10.1158/1538-7445.AM2015-3621

Published: 01 August 2015

View articletitled, Abstract 3621: Deubiquitination of AXIN1 by USP9X promotes apoptosis in melanoma in response to BRAF or MEK inhibition

Journal Articles

Abstract 2323: Mutant B-Raf-mediated activation of deubiquitinases in melanoma defines Usp5 as a potential therapeutic target.

Harish Potu, Luke F. Peterson, Monique Verhaegen, Moshe Talpaz, Nicholas J. Donato

Cancer Res (2013) 73 (8_Supplement): 2323.

https://doi.org/10.1158/1538-7445.AM2013-2323

Published: 15 April 2013

View articletitled, Abstract 2323: Mutant B-Raf-mediated activation of deubiquitinases in melanoma defines Usp5 as a potential therapeutic target.

Journal Articles

Deubiquitinase Inhibition by Small-Molecule WP1130 Triggers Aggresome Formation and Tumor Cell Apoptosis

Vaibhav Kapuria, Luke F. Peterson, Dexing Fang, William G. Bornmann, Moshe Talpaz, Nicholas J. Donato

Cancer Res (2010) 70 (22): 9265–9276.

https://doi.org/10.1158/0008-5472.CAN-10-1530

Published: 14 November 2010

View articletitled, Deubiquitinase Inhibition by Small-Molecule WP1130 Triggers Aggresome Formation and Tumor Cell Apoptosis

Includes: Supplementary data

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Targeting STAT5 or STAT5-Regulated Pathways Suppresses Leukemogenesis of Ph+ Acute Lymphoblastic Leukemia

Targeting CDK6 and BCL2 Exploits the “MYB Addiction” of Ph⁺ Acute Lymphoblastic Leukemia

Abstract 5083: A novel and highly efficacious small-molecule degrader of BET-BRD proteins for the treatment of acute leukemia

Abstract 2881: Deubiquitinase Usp9x controls tumorigenicity through regulation of the Ets-1 transcription factor in melanoma

Abstract 3621: Deubiquitination of AXIN1 by USP9X promotes apoptosis in melanoma in response to BRAF or MEK inhibition

Abstract 2323: Mutant B-Raf-mediated activation of deubiquitinases in melanoma defines Usp5 as a potential therapeutic target.

Deubiquitinase Inhibition by Small-Molecule WP1130 Triggers Aggresome Formation and Tumor Cell Apoptosis

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AACR Journals

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Targeting STAT5 or STAT5-Regulated Pathways Suppresses Leukemogenesis of Ph+ Acute Lymphoblastic Leukemia

Targeting CDK6 and BCL2 Exploits the “MYB Addiction” of Ph+ Acute Lymphoblastic Leukemia

Abstract 5083: A novel and highly efficacious small-molecule degrader of BET-BRD proteins for the treatment of acute leukemia

Abstract 2881: Deubiquitinase Usp9x controls tumorigenicity through regulation of the Ets-1 transcription factor in melanoma

Abstract 3621: Deubiquitination of AXIN1 by USP9X promotes apoptosis in melanoma in response to BRAF or MEK inhibition

Abstract 2323: Mutant B-Raf-mediated activation of deubiquitinases in melanoma defines Usp5 as a potential therapeutic target.

Deubiquitinase Inhibition by Small-Molecule WP1130 Triggers Aggresome Formation and Tumor Cell Apoptosis

Email alerts

AACR Journals

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Targeting CDK6 and BCL2 Exploits the “MYB Addiction” of Ph⁺ Acute Lymphoblastic Leukemia