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Lucio Miele
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Journal Articles

Abstract LB006: Cell marker-based classification of TNBC subtypes and patient outcomes

Zahra Mesrizadeh, Kavitha Mukund, Fokrul Hossain, Jovanny Zabaleta, Denise Danos, Luis Del Valle, Xiao-Cheng Wu, Chindo Hicks, Yuan Chun Ding, Augusto Ochoa, Lucio Miele, Victoria L. Seewaldt, Shankar Subramaniam
Journal: Cancer Research
Cancer Res (2024) 84 (7_Supplement): LB006.
https://doi.org/10.1158/1538-7445.AM2024-LB006
Published: 05 April 2024
View articletitled, Abstract LB006: Cell marker-based classification of TNBC subtypes and patient outcomes
Journal Articles

Abstract LB373: Pilot whole-exome sequencing data of formalin-fixed paraffin embedded endometrial tumors in the Epidemiology of Endometrial Cancer Consortium (E2C2)

Noah C. Peeri, Megan A. Clarke, Immaculata De Vivo, Mengmeng Du, Lucio Miele, Jeffin Naduparambil, Kathryn L. Penney, Venkat Seshan, Ronglai Shen, Veronica W. Setiawan, Nicolas Wentzensen, Xiao-Cheng Wu, Arnold Zea, Wenyu Zhang
Journal: Cancer Research
Cancer Res (2024) 84 (7_Supplement): LB373.
https://doi.org/10.1158/1538-7445.AM2024-LB373
Published: 05 April 2024
View articletitled, Abstract LB373: Pilot whole-exome sequencing data of formalin-fixed paraffin embedded endometrial tumors in the Epidemiology of Endometrial Cancer Consortium (E2C2)
Journal Articles

Abstract 5691: Identification of miRNA related to triple-negative breast cancer in African and European American women with obesity

Fokhrul Hossain, Martha Isabel González-Ramírez, Jone Garai, Xiao-Cheng Wu, Chindo Hicks, Luis Del Valle, Augusto Ochoa, Denise Danos, Lucio Miele, Jovanny Zabaleta
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 5691.
https://doi.org/10.1158/1538-7445.AM2024-5691
Published: 22 March 2024
View articletitled, Abstract 5691: Identification of miRNA related to triple-negative breast cancer in African and European American women with obesity
Journal Articles

Abstract 2064: Targeting Cblb-Notch1 axis as a novel strategy for cancer immunotherapy

Giulia Monticone, Fred Csibi, Silvana Leit, Jermaine E. Austin, Deniz A. Ucar, Fokhrul M. Hossain, Samarpan Majumder, Barbara A. Osborne, Christine Loh, Lucio Miele
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 2064.
https://doi.org/10.1158/1538-7445.AM2022-2064
Published: 15 June 2022
View articletitled, Abstract 2064: Targeting Cblb-Notch1 axis as a novel strategy for cancer immunotherapy
Journal Articles

Abstract 408: Development of a first-in-class notch transcription factor inhibitor CB-103 to overcome resistance to chemotherapy and targeted therapies

Michele Vigolo, Charlotte Urech, Sebastien Lamy, Samarpan Majumder, Lucio Miele, Rajwinder Lehal
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 408.
https://doi.org/10.1158/1538-7445.AM2022-408
Published: 15 June 2022
View articletitled, Abstract 408: Development of a first-in-class notch transcription factor inhibitor CB-103 to overcome resistance to chemotherapy and targeted therapies
Journal Articles

Abstract 4211: Minocycline-based metronomic therapy as a novel approach to enhance anti-tumor immune responses and reduce tumor burden in mouse models of colorectal cancer

Salome V. Ibba, Hanh H. Luu, Mohamed Ghonim, Cecilia Vittori, Matthew J. Dean, Giulia Monticone, Francesca Peruzzi, Augusto Ochoa, Lucio Miele, Hamid A. Boulares
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 4211.
https://doi.org/10.1158/1538-7445.AM2022-4211
Published: 15 June 2022
View articletitled, Abstract 4211: Minocycline-based metronomic therapy as a novel approach to enhance anti-tumor immune responses and reduce tumor burden in mouse models of colorectal cancer
Journal Articles

Abstract 2525: Understanding triple-negative breast cancer immune microenvironment by disease stages, obesity, and race

Fokhrul Hossain, Denise Danos, Jovanny Zabaleta, Jiande Wu, Mary Anne Lynch, Luis Del Valle, Xiao-Cheng Wu, Augusto Ochoa, Chindo Hicks, Lucio Miele
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 2525.
https://doi.org/10.1158/1538-7445.AM2022-2525
Published: 15 June 2022
View articletitled, Abstract 2525: Understanding triple-negative breast cancer immune microenvironment by disease stages, obesity, and race
Journal Articles

Abstract 668: A MYOD-SKP2 axis boosts oncogenic properties of fusion negative rhabdomyosarcoma and is counteracted by neddylation inhibition in vitro and in vivo

Silvia Pomella, Matteo Cassandri, Doris Phelps, Clara Perrone, Michele Pezzella, Marco Wachtel, Benjamin Sunkel, Antonella Cardinale, Zoe Walters, Cristina Cossetti, Sonia Rodriguez, Nadia Carlesso, Janet Shipley, Lucio Miele, Beat Schafer, Enrico Velardi, Peter Houghton, Berkley Gryder, Benjamin Stanton, Concetta Quintarelli, Biagio De Angelis, Franco Locatelli, Rossella Rota
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 668.
https://doi.org/10.1158/1538-7445.AM2022-668
Published: 15 June 2022
View articletitled, Abstract 668: A MYOD-SKP2 axis boosts oncogenic properties of fusion negative rhabdomyosarcoma and is counteracted by neddylation inhibition in vitro and in vivo
Journal Articles

Abstract 2729: Cell infiltration prediction of breast cancer tissues identifies basophils as potentially important immune cells in the tumor microenvironment

Jone Garai, Julie Dutil, Douglas W. Cress, Victoria Seewaldt, Jamie K. Teer, Laura Fejerman, Lucio Miele, Jovanny Zabaleta
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2729.
https://doi.org/10.1158/1538-7445.AM2021-2729
Published: 01 July 2021
View articletitled, Abstract 2729: Cell infiltration prediction of breast cancer tissues identifies basophils as potentially important immune cells in the tumor microenvironment
Journal Articles

Abstract 3866: Investigating tumor infiltrating immune cells signature in obese triple negative breast cancer

Fokhrul Hossain, Deniz A Ucar, Maria Sanchez-Pino, Matthew Dean, Samarpan Majumder, Dorota Wyczechowska, Giulia Monticone, Rachel Sabol, Keli Xu, Luis D Valle, Jovanny Zabaleta, Bruce Bunnell, Lucio Miele
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 3866.
https://doi.org/10.1158/1538-7445.AM2020-3866
Published: 15 August 2020
View articletitled, Abstract 3866: Investigating tumor infiltrating immune cells signature in obese triple negative breast cancer
Journal Articles

Abstract 6691: Delivering intra-tumoral immune modulators and targeting cancer stem cells using recombinant- AAVs

Deniz A. Ucar, Giulia Monticone, Fokhrul Hossain, Samarpan Majumder, Dorota Wyczechowska, Matthew J. Dean, Luis Del Valle, Jovanny Zabaleta, Yong Ran, Sudarvili Shanthalingam, Abraham Bert Chabot, Bridgette M. Collins-Burow, Matthew E. Burrow, Barbara Osborne, Todd Eliot Golde, Lucio Miele
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 6691.
https://doi.org/10.1158/1538-7445.AM2020-6691
Published: 15 August 2020
View articletitled, Abstract 6691: Delivering intra-tumoral immune modulators and targeting cancer stem cells using recombinant- AAVs
Journal Articles

Abstract 4517: Targeting Notch1 via adenosine A2A receptor to modulate tumor immunity

Giulia Monticone, Fokhrul M. Hossain, Deniz A. Ucar, Samarpan Majumder, Claudia Sorrentino, Paulo C. Rodriguez, Rosa A. Sierra, Antonio Pannuti, Stephen Hatfield, Barbara A. Osborne, Lisa M. Minter, Silvana Morello, Lucio Miele
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 4517.
https://doi.org/10.1158/1538-7445.AM2020-4517
Published: 15 August 2020
View articletitled, Abstract 4517: Targeting Notch1 via adenosine A2A receptor to modulate tumor immunity
Journal Articles

Abstract P5-04-19: Sulindac sulfide as a non-immune suppressive gamma secretase modifier to target triple negative breast cancer

Fokhrul Hossain, Deniz A Ucar, Samarpan Majumder, Margarite Matossian, Giulia Monticone, Keli Xu, Yong Ran, Lisa Minter, Yaguang Xi, Matthew Burow, Todd Golde, Barbara Osborne, Lucio Miele
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): P5-04-19.
https://doi.org/10.1158/1538-7445.SABCS19-P5-04-19
Published: 15 February 2020
View articletitled, Abstract P5-04-19: Sulindac sulfide as a non-immune suppressive gamma secretase modifier to target triple negative breast cancer
Journal Articles

Abstract P6-03-17: Effect of histone deacetylase inhibitors on patient-derived neoadjuvant chemotherapy resistant triple negative breast cancer xenografts that represent understudied patients

Margarite Matossian, Steven Elliott, Maryl Wright, Tiffany Chang, Madlin Alzoubi, Henri Wathieu, Rachel Sabol, Alex Alfortish, Hope Burks, Van Hoang, Deniz Ucar, Gabrielle Windsor, Thomas Yan, Jovanny Zabaleta, Fokhrul Hossain, Bruce Bunnell, Krzysztof Moroz, Arnold Zea, Adam Riker, Steven Jones, Elizabeth Martin, Lucio Miele, Bridgette Collins-Burow, Matthew Burow
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): P6-03-17.
https://doi.org/10.1158/1538-7445.SABCS19-P6-03-17
Published: 15 February 2020
View articletitled, Abstract P6-03-17: Effect of histone deacetylase inhibitors on patient-derived neoadjuvant chemotherapy resistant triple negative breast cancer xenografts that represent understudied patients
Journal Articles

Abstract 5250: Notch signaling in ER+ breast cancer in response to endocrine therapy agents

Ciera S. Singleton, Lucio Miele, Judy S. Crabtree
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 5250.
https://doi.org/10.1158/1538-7445.AM2019-5250
Published: 01 July 2019
View articletitled, Abstract 5250: Notch signaling in ER+ breast cancer in response to endocrine therapy agents
Journal Articles

Abstract 3439: Sulindac sulfide as a gamma secretase modifier to target triple negative breast cancer

Fokhrul Hossain, Deniz A Ucar, Samarpan Majumder, Margarite Matossian, Keli Xu, Yong Ran, Lisa Minter, Yaguang Xi, Matthew Burow, Todd Golde, Barbara Osborne, Lucio Miele
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 3439.
https://doi.org/10.1158/1538-7445.AM2019-3439
Published: 01 July 2019
View articletitled, Abstract 3439: Sulindac sulfide as a gamma secretase modifier to target triple negative breast cancer
Journal Articles

Abstract 967: Targeting notch one notch above

Deniz A. Ucar-Bilyeu, Margarite D. MATOSSIAN, VAN Hoang Barnes, Fokhrul M. Hossain, Mohit Gupta, HOPE E. BURKS, THOMAS D. WRIGHT, Jane Cavanaugh, Patrick Flaherty, Matthew E. Burow, Lucio Miele
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 967.
https://doi.org/10.1158/1538-7445.AM2018-967
Published: 01 July 2018
View articletitled, Abstract 967: Targeting notch one notch above
Journal Articles

Abstract 3010: Biobanking and genomic research: Understanding and acceptance of safety-net patients, primary care providers and minority groups

Terry Davis, Connie Arnold, Lucio Miele, Glenn Mills
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 3010.
https://doi.org/10.1158/1538-7445.AM2018-3010
Published: 01 July 2018
View articletitled, Abstract 3010: Biobanking and genomic research: Understanding and acceptance of safety-net patients, primary care providers and minority groups
Journal Articles

Abstract 157: Targeting cancer stem-like cells in triple negative breast cancer

Fokhrul Hossain, Ayse D Ucar Bilyeu, Claudia Sorrentino, Judy Crabtree, Antonio Pannuti, Margarite Matossian, Matthew Burow, Todd Golde, Barbara Osborne, Lucio Miele
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 157.
https://doi.org/10.1158/1538-7445.AM2018-157
Published: 01 July 2018
View articletitled, Abstract 157: Targeting cancer stem-like cells in triple negative breast cancer
Journal Articles

Anti-Jagged Immunotherapy Inhibits MDSCs and Overcomes Tumor-Induced Tolerance

Rosa A. Sierra, Jimena Trillo-Tinoco, Eslam Mohamed, Lolie Yu, Bhagelu R. Achyut, Ali Arbab, Jennifer W. Bradford, Barbara A. Osborne, Lucio Miele, Paulo C. Rodriguez
Journal: Cancer Research
Cancer Res (2017) 77 (20): 5628–5638.
https://doi.org/10.1158/0008-5472.CAN-17-0357
Published: 15 October 2017
View articletitled, Anti-Jagged Immunotherapy Inhibits MDSCs and Overcomes Tumor-Induced Tolerance
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Includes: Supplementary data