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Luciano Cascione
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Journal Articles

Abstract 410: The BTK degrader BGB-16673 shows anti-tumor activity in marginal zone lymphoma models

Alberto J. Arribas, Elisa Civanelli, Camilla Scalise, Luciano Cascione, Andrea Rinaldi, Davide Rossi, Emanuele Zucca, Francesco Bertoni
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 410.
https://doi.org/10.1158/1538-7445.AM2025-410
Published: 21 April 2025
View articletitled, Abstract 410: The BTK degrader BGB-16673 shows anti-tumor activity in marginal zone lymphoma models
Journal Articles

Abstract 7332: Investigating genes and pathways determining sensitivity or resistance to anti-L1cam ADCs in lymphomas

Filippo Spriano, Giulio Sartori, Chiara Tarantelli, Luciano Cascione, Sara Napoli, Flavio Mehli, Gunther Spohn, Francesco Bertoni
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 7332.
https://doi.org/10.1158/1538-7445.AM2025-7332
Published: 21 April 2025
View articletitled, Abstract 7332: Investigating genes and pathways determining sensitivity or resistance to anti-L1cam ADCs in lymphomas
Journal Articles

Abstract 5836: CRISPR/Cas9 screening identifies genes affecting the sensitivity to the copanlisib/venetoclax combination in lymphoma cells

Sara Napoli, Alberto J. Arribas, Eleonora Cannas, Federica Fuzio, Luciano Cascione, Andrea Rinaldi, Emanuele Zucca, Andrea Alimonti, Anastasios Stathis, Francesco Bertoni
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 5836.
https://doi.org/10.1158/1538-7445.AM2024-5836
Published: 22 March 2024
View articletitled, Abstract 5836: CRISPR/Cas9 screening identifies genes affecting the sensitivity to the copanlisib/venetoclax combination in lymphoma cells
Journal Articles

Abstract 534: Novel marginal zone lymphoma models of resistance to the dual inhibition of PI3K and BCL2

Alberto J. Arribas, Luciano Cascione, Eleonora Cannas, Helen Bellerjeau, Federica Fuzio, Aleix Noguera, Andrea Rinaldi, Manel Esteller, Emanuele Zucca, Andrea Alimonti, Davide Rossi, Anastasios Stathis, Francesco Bertoni
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 534.
https://doi.org/10.1158/1538-7445.AM2024-534
Published: 22 March 2024
View articletitled, Abstract 534: Novel marginal zone lymphoma models of resistance to the dual inhibition of PI3K and BCL2
Journal Articles

Abstract 2721: FF01: a novel humanized heavy chain antibody targeting endogenous retroviruses with anti-lymphoma activity

Filippo Spriano, Luciano Cascione, Jacopo Sgrignani, Nikolai Bendik, Sara Napoli, Giulio Sartori, Eleonora Cannas, Tao Gongo, Alberto J. Arribas, Davide Rossi, Davide F. Robbiani, Andrea Cavalli, Francesco Bertoni
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 2721.
https://doi.org/10.1158/1538-7445.AM2024-2721
Published: 22 March 2024
View articletitled, Abstract 2721: FF01: a novel humanized heavy chain antibody targeting endogenous retroviruses with anti-lymphoma activity
Journal Articles

Abstract 463: The small nucleolar RNA SNORD46 and SNORD72 have tumor suppressor activity in diffuse large B cell lymphoma

Elaine YL Chung, Filippo Spriano, Sara Napoli, Giulio Sartori, Luciano Cascione, Francesco Bertoni
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 463.
https://doi.org/10.1158/1538-7445.AM2024-463
Published: 22 March 2024
View articletitled, Abstract 463: The small nucleolar RNA SNORD46 and SNORD72 have tumor suppressor activity in diffuse large B cell lymphoma
Journal Articles

Abstract 492: Pharmacological inhibition of CXCR4 increases the anti-tumor activity of conventional and targeted therapies in B cell lymphoma models

Laura Barnabei, Alberto J. Arribas, Luciano Cascione, Francesca Guidetti, Filippo Spriano, Chiara Tarantelli, Andrea Rinaldi, Anastasios Stathis, Davide Rossi, Emanuele Zucca, Johann Zimmermann, Francesco Bertoni
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 492.
https://doi.org/10.1158/1538-7445.AM2023-492
Published: 04 April 2023
View articletitled, Abstract 492: Pharmacological inhibition of CXCR4 increases the anti-tumor activity of conventional and targeted therapies in B cell lymphoma models
Journal Articles

Abstract 394: ERBB4-mediated signaling is a mediator of resistance to BTK and PI3K inhibitors in B cell lymphoid neoplasms

Alberto J. Arribas, Sara Napoli, Luciano Cascione, Laura Barnabei, Giulio Sartori, Eleonora Cannas, Eugenio Gaudio, Chiara Tarantelli, Afua A. Mensah, Filippo Spriano, Antonella Zucchetto, Francesca M. Rossi, Andrea Rinaldi, Manuel Castro de Moura, Anastasios Stathis, Georg Stussi, Valter Gattei, Jennifer R. Brown, Manel Esteller, Emanuele Zucca, Davide Rossi, Francesco Bertoni
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 394.
https://doi.org/10.1158/1538-7445.AM2023-394
Published: 04 April 2023
View articletitled, Abstract 394: ERBB4-mediated signaling is a mediator of resistance to BTK and PI3K inhibitors in B cell lymphoid neoplasms
Journal Articles

Abstract 3279: Dual inhibition of EZH2 and histone deacetylases for the treatment of lymphomas with epigenetic aberrations

Afua Adjeiwaa Mensah, Sergio Valente, Milos Matkovic, Giulio Sartori, Chiara Falzarano, Chiara Tarantelli, Luciano Cascione, Stefano A. Pileri, Andrea Cavalli, Antonello Mai, Francesco Bertoni
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 3279.
https://doi.org/10.1158/1538-7445.AM2022-3279
Published: 15 June 2022
View articletitled, Abstract 3279: Dual inhibition of EZH2 and histone deacetylases for the treatment of lymphomas with epigenetic aberrations
Journal Articles

Abstract 2575: Avanbulin, the active moiety of the tumor checkpoint controller lisavanbulin (BAL101553), has anti-lymphoma activity

Filippo Spriano, Luca Aresu, Luciano Cascione, Alberto J. Arribas, Nicole Forster-Gross, Felix Bachmann, Heidi Lane, Francesco Bertoni
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 2575.
https://doi.org/10.1158/1538-7445.AM2022-2575
Published: 15 June 2022
View articletitled, Abstract 2575: Avanbulin, the active moiety of the tumor checkpoint controller lisavanbulin (BAL101553), has anti-lymphoma activity
Journal Articles

Abstract 2655: The GPCR OR13A1 is essential for lymphoma cells

Giulio Sartori, Luciano Cascione, Milos Matkovic, Hiroaki Matsunami, Andrea Cavalli, Francesco Bertoni
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 2655.
https://doi.org/10.1158/1538-7445.AM2022-2655
Published: 15 June 2022
View articletitled, Abstract 2655: The GPCR OR13A1 is essential for lymphoma cells
Journal Articles

Abstract 2373: Expression of exosomal let-7g in biofluids and outcome in colon cancer patient treated with anti-EGFR therapy

Jens C. Hahne, Andrea Lampis, Michele Ghidini, Margherita Ratti, Chiara Senti, Rodolfo Passalacqua, Luciano Cascione, Chiara Braconi, Owen Sansom, Matteo Fassan, Nicola Valeri
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2373.
https://doi.org/10.1158/1538-7445.AM2021-2373
Published: 01 July 2021
View articletitled, Abstract 2373: Expression of exosomal let-7g in biofluids and outcome in colon cancer patient treated with anti-EGFR therapy
Journal Articles

Abstract 474: Extracellular vesicle - MDM2 as liquid biopsy biomarker for disease identification in retroperitoneal liposarcoma

Lucia Casadei, Patricia Sarchet, Luciano Cascione, Giovanni Nigita, Fernanda Costas Casal de Faria, Carlo Maria Croce, Valerie Grignol, Raphael E. Pollock
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 474.
https://doi.org/10.1158/1538-7445.AM2021-474
Published: 01 July 2021
View articletitled, Abstract 474: Extracellular vesicle - MDM2 as liquid biopsy biomarker for disease identification in retroperitoneal liposarcoma
Journal Articles

Abstract 1417: Development of a miRNA-based prediction tool to discriminate cutaneous blastic plasmacytoid dendritic cell neoplasm from cutaneous myeloid sarcoma

Maria Rosaria Sapienza, Fabio Fuligni, Federica Melle, Valentina Tabanelli, Valentina Indio, Alessandro Pileri, Lorenzo Cerroni, Francesco Bacci, Giovanna Motta, Maria Antonella Laginestra, Saveria Mazzara, Luciano Cascione, Alessandro Laganà, Claudio Agostinelli, Manuela Ferracin, Elena Sabattini, Carlo Croce, Stefano Pileri
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 1417.
https://doi.org/10.1158/1538-7445.AM2020-1417
Published: 15 August 2020
View articletitled, Abstract 1417: Development of a miRNA-based prediction tool to discriminate cutaneous blastic plasmacytoid dendritic cell neoplasm from cutaneous myeloid sarcoma
Journal Articles

Abstract 163: DNA methyltransferase modulation in lymphoma cells involves functional redundancy and maintains hypermethylation of selected regions

Raffaele Frazzi, Vincenza Ylenia Cusenza, Luciano Cascione, Andrea Rinaldi, Francesco Bertoni, Mariaelena Pistoni, Francesco Merli
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 163.
https://doi.org/10.1158/1538-7445.AM2020-163
Published: 15 August 2020
View articletitled, Abstract 163: DNA methyltransferase modulation in lymphoma cells involves functional redundancy and maintains hypermethylation of selected regions
Journal Articles

Abstract 5215: Inhibition of PIM kinases targets synthetic vulnerabilities and enhances antigen presentation in B cell lymphoma

Patrizia Mondello, Chiara Tarantelli, Luciano Cascione, Alberto J. Arribas, Andrea Rinaldi, Anas Younes, Francesco Bertoni
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 5215.
https://doi.org/10.1158/1538-7445.AM2020-5215
Published: 15 August 2020
View articletitled, Abstract 5215: Inhibition of PIM kinases targets synthetic vulnerabilities and enhances antigen presentation in B cell lymphoma
Journal Articles

Abstract 4206: EUD-GK-001 is a novel kinase inhibitor with in vitro anti-lymphoma activity

Lorenzo Scalise, Chiara Tarantelli, Fabio Zuccotto, Filippo Spriano, Michele Mascia, Luciano Cascione, Eugenio Gaudio, Mauro Angiolini, Francesco Bertoni
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 4206.
https://doi.org/10.1158/1538-7445.AM2020-4206
Published: 15 August 2020
View articletitled, Abstract 4206: EUD-GK-001 is a novel kinase inhibitor with in vitro anti-lymphoma activity
Journal Articles

Abstract 3829: NEO1132 and NEO2734, novel dual bromodomain inhibitors of both BET and CREBBP/EP300, compared to single BET or CREBB/EP300 inhibitors in diffuse large B cell lymphoma

Filippo Spriano, Eugenio Gaudio, Chiara Tarantelli, Gaetanina Golino, Luciano Cascione, Emanuele Zucca, Anastasios Stathis, Francis Giles, Francesco Bertoni
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 3829.
https://doi.org/10.1158/1538-7445.AM2019-3829
Published: 01 July 2019
View articletitled, Abstract 3829: NEO1132 and NEO2734, novel dual bromodomain inhibitors of both BET and CREBBP/EP300, compared to single BET or CREBB/EP300 inhibitors in diffuse large B cell lymphoma
Journal Articles

Abstract 274: The ATR inhibitor BAY 1895344 shows strong preclinical activity in lymphomas and appears associated with specific gene expression signatures

Eugenio Gaudio, Chiara Tarantelli, Filippo Spriano, Luciano Cascione, Alberto Arribas, Emanuele Zucca, Anastasios Stathis, Antje Margret Wengner, Francesco Bertoni
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 274.
https://doi.org/10.1158/1538-7445.AM2019-274
Published: 01 July 2019
View articletitled, Abstract 274: The ATR inhibitor BAY 1895344 shows strong preclinical activity in lymphomas and appears associated with specific gene expression signatures
Journal Articles

Abstract 1805: Integrative analysis of microRNAs in blastic plasmacytoid dendritic cell neoplasm

Maria Rosaria Sapienza, Manuela Ferracin, Fabio Fuligni, Federica Melle, Giovanna Motta, Maria Antonella Laginestra, Maura Rossi, Luciano Cascione, Alessandro Laganà, Claudio Agostinelli, Elena Sabattini, Alessandro Pileri, Carlo Maria Croce, Stefano Aldo Pileri
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 1805.
https://doi.org/10.1158/1538-7445.AM2019-1805
Published: 01 July 2019
View articletitled, Abstract 1805: Integrative analysis of microRNAs in blastic plasmacytoid dendritic cell neoplasm