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Louis M. Weiner
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Journal Articles

AACR Cancer Centers Alliance: Fostering Collaboration and Innovation to Advance Lifesaving Scientific Discoveries for Patients

Carlos L. Arteaga, John L. Cleveland, Margaret Foti, Ruben A. Mesa, Louis M. Weiner, Cheryl L. Willman, David A. Tuveson
Journal: Cancer Research
Cancer Res (2023) 83 (21): 3504–3506.
https://doi.org/10.1158/0008-5472.CAN-23-2803
Published: 01 November 2023
View article titled, AACR Cancer Centers Alliance: Fostering Collaboration and Innovation to Advance Lifesaving Scientific Discoveries for Patients
Open the PDF for AACR Cancer Centers Alliance: Fostering Collaboration and Innovation to Advance Lifesaving Scientific Discoveries for Patients in another window
Journal Articles

Abstract 6169: Identification of molecules mediating natural killer cell-pancreatic stellate cell interactions

Zoe X. Malchiodi, Allison Fitzgerald, Elena Galvano, Louis M. Weiner
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 6169.
https://doi.org/10.1158/1538-7445.AM2022-6169
Published: 15 June 2022
View article titled, Abstract 6169: Identification of molecules mediating natural killer cell-pancreatic stellate cell interactions
Journal Articles

Abstract 3413: Transfer learning identifies common cellular determinants of immune checkpoint inhibitor response between preclinical tumor models and patients

Emily F. Davis-Marcisak, Allison A. Fitzgerald, Neeha Zaidi, Elizabeth M. Jaffee, Louis M. Weiner, Elana J. Fertig
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 3413.
https://doi.org/10.1158/1538-7445.AM2020-3413
Published: 15 August 2020
View article titled, Abstract 3413: Transfer learning identifies common cellular determinants of immune checkpoint inhibitor response between preclinical tumor models and patients
Journal Articles

Abstract 6636: Therapy with BXCL701 (B), a DPP8, DPP9, DPPIV and FAP inhibitor, in combination with anti-PD1 antibody (PD1) in a syngeneic murine pancreatic ductal adenocarcinoma (PDAC) model improves treatment outcomes and induces intratumoral NK cell infiltrates and a marked reduction in tumor stromal fibrosis

Shangzi Wang, Allison Fitzgerald, Reham Ajina, Sandra A. Jablonsk, Louis M. Weiner, John MacDougall, Veena Agarwal, Vince J. O'Neill
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 6636.
https://doi.org/10.1158/1538-7445.AM2020-6636
Published: 15 August 2020
View article titled, Abstract 6636: Therapy with BXCL701 (B), a DPP8, DPP9, DPPIV and FAP inhibitor, in combination with anti-PD1 antibody (PD1) in a syngeneic murine pancreatic ductal adenocarcinoma (PDAC) model improves treatment outcomes and induces intratumoral NK cell infiltrates and a marked reduction in tumor stromal fibrosis
Journal Articles

Abstract 4584: Malignant pancreatic cancer cells respond to immune selection pressure to foster immunosuppression

Reham Ajina, Annie Zuo, Maha Moussa, Sarah J. Cooper, Yue Shen, Quentin R. Johnson, Jerry M. Parks, Jeremy C. Smith, Elana Fertig, Marta Catalfamo, Sandra A. Jablonski, Louis M. Weiner
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 4584.
https://doi.org/10.1158/1538-7445.AM2019-4584
Published: 01 July 2019
View article titled, Abstract 4584: Malignant pancreatic cancer cells respond to immune selection pressure to foster immunosuppression
Journal Articles

Abstract 633: Induction of ADCC resistance profoundly alters tumor cell phenotype and stress response

Dalal S. Aldeghaither, Joseph C. Murray, Sarah M. Roth, Elana J. Fertig, Shaojun Tang, Sandra A. Jablonski, Louis M. Weiner
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 633.
https://doi.org/10.1158/1538-7445.AM2017-633
Published: 01 July 2017
View article titled, Abstract 633: Induction of ADCC resistance profoundly alters tumor cell phenotype and stress response
Journal Articles

Abstract 2604: The Georgetown Database of Cancer (G-DOC): A web-based data sharing platform for precision medicine

Krithika Bhuvaneshwar, Anas Belouali, Shruti Rao, Adil Alaoui, Yuriy Gusev, Robert Clarke, Louis M. Weiner, Subha Madhavan
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 2604.
https://doi.org/10.1158/1538-7445.AM2017-2604
Published: 01 July 2017
View article titled, Abstract 2604: The Georgetown Database of Cancer (G-DOC): A web-based data sharing platform for precision medicine
Journal Articles

Abstract A77: Screening of conditionally reprogrammed patient-derived carcinoma cells identifies ERCC3-MYC interactions as a target in pancreatic cancer

Igor Astsaturov, Sandra A. Jablonski, Yan Zhou, Ilya Serebriiskii, Paz Keren, Louis M. Weiner, Erica Golemis, Vladimir Khazak
Journal: Cancer Research
Cancer Res (2016) 76 (24_Supplement): A77.
https://doi.org/10.1158/1538-7445.PANCA16-A77
Published: 14 December 2016
View article titled, Abstract A77: Screening of conditionally reprogrammed patient-derived carcinoma cells identifies ERCC3-MYC interactions as a target in pancreatic cancer
Journal Articles

Abstract 4023: Combination therapy with immune checkpoint inhibitor and CCK-receptor blockade increases survival of pancreatic cancer

Jill P. Smith, Shangzi Wang, Ajina Reham, Sandra A. Jablonski, Louis M. Weiner
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 4023.
https://doi.org/10.1158/1538-7445.AM2016-4023
Published: 15 July 2016
View article titled, Abstract 4023: Combination therapy with immune checkpoint inhibitor and CCK-receptor blockade increases survival of pancreatic cancer
Journal Articles

Abstract B44: Keratin-associated protein 5-5 controls cytoskeletal function and cancer cell vascular invasion

Eric B. Berens, Ghada M. Sharif, Marcel O. Schmidt, Casey W. Shuptrine, Louis M. Weiner, Eric Glasgow, Anna T. Riegel, Anton Wellstein
Journal: Cancer Research
Cancer Res (2016) 76 (7_Supplement): B44.
https://doi.org/10.1158/1538-7445.TUMMET15-B44
Published: 26 May 2016
View article titled, Abstract B44: Keratin-associated protein 5-5 controls cytoskeletal function and cancer cell vascular invasion
Journal Articles

Abstract 1465: Development of patient-derived platform to assess activity of anticancer agents in pancreatic cancer

Vladimir Khazak, Natalia Skobeleva, Natalia Beglyarova, Eugenia Banina, Elena Lysenko, Igor Astsaturov, Sandra A. Jablonski, Louis M. Weiner, Ilya Serebriiskii, David A. Proia
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 1465.
https://doi.org/10.1158/1538-7445.AM2015-1465
Published: 01 August 2015
View article titled, Abstract 1465: Development of patient-derived platform to assess activity of anticancer agents in pancreatic cancer
Journal Articles

Abstract 1716: Acquisition of estrogen independence induces TOB1-related mechanisms supporting breast cancer cell proliferation

Yong-Wei Zhang, Rochelle E. Nasto, Rency Varghese, Sandra A. Jablonski, Ilya G. Serebriiskii, Rishi Surana, Valerie S. Calvert, Ionut Bebu, Joseph Murray, Lu Jin, Michael Johnson, Rebecca Riggins, Habtom Ressom, Emmanuel Petricoin III, Robert Clarke, Erica A. Golemis, Louis M. Weiner
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 1716.
https://doi.org/10.1158/1538-7445.AM2015-1716
Published: 01 August 2015
View article titled, Abstract 1716: Acquisition of estrogen independence induces TOB1-related mechanisms supporting breast cancer cell proliferation
Journal Articles

Abstract 5362: Deficiencies in mismatch repair proteins induce elevated levels of acrolein-derived 1,N2-propanodeoxyguanosine and apoptosis in human colon cancer cells treated with acrolein

Jishen Pan, Zhuoli Xuan, Marcin Dyba, Yongwei Zhang, Ying Fu, Rabindra Roy, Louis M. Weiner, Fung-Lung Chung
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 5362.
https://doi.org/10.1158/1538-7445.AM2014-5362
Published: 01 October 2014
View article titled, Abstract 5362: Deficiencies in mismatch repair proteins induce elevated levels of acrolein-derived 1,<em>N</em><sup>2</sup>-propanodeoxyguanosine and apoptosis in human colon cancer cells treated with acrolein
Journal Articles

Abstract 2042: TOB1 promotes cell survival in estrogen-independent estrogen receptor-positive breast cancer.

Yong-Wei Zhang, Rochelle Nasto, Robert Clarke, Louis M. Weiner
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 2042.
https://doi.org/10.1158/1538-7445.AM2013-2042
Published: 15 April 2013
View article titled, Abstract 2042: TOB1 promotes cell survival in estrogen-independent estrogen receptor-positive breast cancer.
Journal Articles

Abstract 2689: Drivers of cancer cell invasion and metastasis.

Ghada M. Sharif, Marcel O. Schmidt, Casey Shuptrine, Louis M. Weiner, Zhang-Zhi Hu, Anna T. Riegel, Anton Wellstein
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 2689.
https://doi.org/10.1158/1538-7445.AM2013-2689
Published: 15 April 2013
View article titled, Abstract 2689: Drivers of cancer cell invasion and metastasis.
Journal Articles

Abstract 2847: Molecular determinants of sensitivity and resistance to tumor-directed antibody-dependent cellular cytotoxicity (ADCC).

Joseph C. Murray, Rochelle E. Nasto, Sandra A. Jablonski, Yong Tang, Louis M. Weiner
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 2847.
https://doi.org/10.1158/1538-7445.AM2013-2847
Published: 15 April 2013
View article titled, Abstract 2847: Molecular determinants of sensitivity and resistance to tumor-directed antibody-dependent cellular cytotoxicity (ADCC).
Journal Articles

Abstract 4667: Circulating microRNA profile predicts disease progression in patients receiving second-line treatment of lapatinib and capecitabine for metastatic pancreatic cancer.

Zheng Wu, Narayan Shivapurkar, John L. Marshall, Jimmy Hwang, Michael J. Pishvaian, Tingting Zhuang, Anton Wellstein, Louis M. Weiner, Lisa Ley, Aiwu R. He
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 4667.
https://doi.org/10.1158/1538-7445.AM2013-4667
Published: 15 April 2013
View article titled, Abstract 4667: Circulating microRNA profile predicts disease progression in patients receiving second-line treatment of lapatinib and capecitabine for metastatic pancreatic cancer.
Journal Articles

Abstract LB-128: Targeted RNAi screening of an EGFR network reveals molecular determinants of tumor cell sensitivity to antibody-dependent cellular cytotoxicity (ADCC)

Joseph C. Murray, Rochelle E. Nasto, Sandra A. Jablonski, Yong Tang, Louis M. Weiner
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): LB-128.
https://doi.org/10.1158/1538-7445.AM2012-LB-128
Published: 15 April 2012
View article titled, Abstract LB-128: Targeted RNAi screening of an EGFR network reveals molecular determinants of tumor cell sensitivity to antibody-dependent cellular cytotoxicity (ADCC)
Journal Articles

Influence of Affinity and Antigen Internalization on the Uptake and Penetration of Anti-HER2 Antibodies in Solid Tumors

Stephen I. Rudnick, Jianlong Lou, Calvin C. Shaller, Yong Tang, Andres J.P. Klein-Szanto, Louis M. Weiner, James D. Marks, Gregory P. Adams
Journal: Cancer Research
Cancer Res (2011) 71 (6): 2250–2259.
https://doi.org/10.1158/0008-5472.CAN-10-2277
Published: 14 March 2011
View article titled, Influence of Affinity and Antigen Internalization on the Uptake and Penetration of Anti-HER2 Antibodies in Solid Tumors
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Includes: Supplementary data
Journal Articles

Abstract 2014: An estrogen receptor - centered network for probing anti-estrogen drug resistance with siRNA screening technology

Rochelle E. Nasto, Ilya Serebriiskii, Sandra A. Jablonski, Michael D. Johnson, Robert Clarke, Louis M. Weiner, Erica A. Golemis
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 2014.
https://doi.org/10.1158/1538-7445.AM10-2014
Published: 15 April 2010
View article titled, Abstract 2014: An estrogen receptor - centered network for probing anti-estrogen drug resistance with siRNA screening technology