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Journal Articles

Abstract 2863: CDKN1A prevents IR-induced apoptosis in rhabdomyosarcoma tumor via repressing the pro-apoptotic factor NOXA in a novel apoptotic regulatory axis

Paulomi S. Modi, Myron Ignatius, Long Wang, Prethish Sreenivas
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 2863.
https://doi.org/10.1158/1538-7445.AM2024-2863
Published: 22 March 2024
View article titled, Abstract 2863: <em>CDKN1A</em> prevents IR-induced apoptosis in rhabdomyosarcoma tumor via repressing the pro-apoptotic factor NOXA in a novel apoptotic regulatory axis
Journal Articles

Abstract 3762: 11,000-plex aptamer based proteomics of bladder cancer urine for the discovery of novel disease biomarkers

Chandra Mohan, Kamala Vanarsa, Jessica Castillo, Long Wang, Yair Lotan
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 3762.
https://doi.org/10.1158/1538-7445.AM2024-3762
Published: 22 March 2024
View article titled, Abstract 3762: 11,000-plex aptamer based proteomics of bladder cancer urine for the discovery of novel disease biomarkers
Journal Articles

Abstract 4596: Targeting arginine methylome in 9p21/MTAP-deleted malignant cancers with a next generation PRMT5-specific inhibitor CTS3497

Yilin Liu, Long Wang, Hui Shi, Yuanyuan Liu, Qiugeng Ouyang, Xingnian Fu, Meng Wang, Jiannan Guo, Yiqin Wang, Youzhen Wang, Guoliang Xu, Yuan Mi, Haiping Wu
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 4596.
https://doi.org/10.1158/1538-7445.AM2024-4596
Published: 22 March 2024
View article titled, Abstract 4596: Targeting arginine methylome in <em>9p21</em>/<em>MTAP</em>-deleted malignant cancers with a next generation PRMT5-specific inhibitor CTS3497
Journal Articles

PICH Activates Cyclin A1 Transcription to Drive S-Phase Progression and Chemoresistance in Gastric Cancer

Huili Ye, Wengui Shi, Jing Yang, Long Wang, Xiangyan Jiang, Huiming Zhao, Long Qin, Junjie Qin, Lianshun Li, Weiwen Cai, Junhong Guan, Hanteng Yang, Huinian Zhou, Zeyuan Yu, Hui Sun, Zuoyi Jiao
Journal: Cancer Research
Cancer Res (2023) 83 (22): 3767–3782.
https://doi.org/10.1158/0008-5472.CAN-23-1331
Published: 15 November 2023
View article titled, PICH Activates Cyclin A1 Transcription to Drive S-Phase Progression and Chemoresistance in Gastric Cancer
Open the PDF for PICH Activates Cyclin A1 Transcription to Drive S-Phase Progression and Chemoresistance in Gastric Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract 1465: A SNAI2/CDKN1A pathway protects rhabdomyosarcoma tumors from radiation

Paulomi S. Modi, Long Wang, Prethish Sreenivas, Myron Ignatius
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 1465.
https://doi.org/10.1158/1538-7445.AM2023-1465
Published: 04 April 2023
View article titled, Abstract 1465: A <em>SNAI2/CDKN1A</em> pathway protects rhabdomyosarcoma tumors from radiation
Journal Articles

Abstract 6278: Combination therapeutic strategy with type I PRMT inhibition in cancer treatment

Hui Shi, Xingnian Fu, Yilin Liu, Qiugeng Ouyang, Meng Wang, Jiaxin Huang, Long Wang, Youzhen Wang, Yuan Mi, Haiping Wu
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 6278.
https://doi.org/10.1158/1538-7445.AM2023-6278
Published: 04 April 2023
View article titled, Abstract 6278: Combination therapeutic strategy with type I PRMT inhibition in cancer treatment
Journal Articles

Abstract 6273: CTS3157, a novel MTA-cooperative PRMT5 inhibitor for targeting MTAP-deleted human tumors

Long Wang, Yilin Liu, Hui Shi, Yuanyuan Liu, Qiugeng Ouyang, Jiannan Guo, Yiqin Wang, Youzhen Wang, Guoliang Xu, Yuan Mi, Haiping Wu
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 6273.
https://doi.org/10.1158/1538-7445.AM2023-6273
Published: 04 April 2023
View article titled, Abstract 6273: CTS3157, a novel MTA-cooperative PRMT5 inhibitor for targeting <em>MTAP</em>-deleted human tumors
Journal Articles

SNAI2-Mediated Repression of BIM Protects Rhabdomyosarcoma from Ionizing Radiation

Long Wang, Nicole R. Hensch, Kathryn Bondra, Prethish Sreenivas, Xiang R. Zhao, Jiangfei Chen, Rodrigo Moreno Campos, Kunal Baxi, Angelina V. Vaseva, Benjamin D. Sunkel, Berkley E. Gryder, Silvia Pomella, Benjamin Z. Stanton, Siyuan Zheng, Eleanor Y. Chen, Rossella Rota, Javed Khan, Peter J. Houghton, Myron S. Ignatius
Journal: Cancer Research
Cancer Res (2021) 81 (21): 5451–5463.
https://doi.org/10.1158/0008-5472.CAN-20-4191
Published: 01 November 2021
View article titled, SNAI2-Mediated Repression of <em>BIM</em> Protects Rhabdomyosarcoma from Ionizing Radiation
Open the PDF for SNAI2-Mediated Repression of <em>BIM</em> Protects Rhabdomyosarcoma from Ionizing Radiation in another window
Includes: Supplementary data
Journal Articles

Abstract LB251: Vertical inhibition of the RAF MEK ERK cascade induces myogenic differentiation, apoptosis and tumor regression in H/NRAS Q61X mutant rhabdomyosarcoma

Natalia Garcia, Vanessa Del-Pozo, Marielle Yohe, Craig Goodwin, Terry Shackleford, Long Wang, Kunal Baxi, Yidong Chen, Myron Ignatius, Kris Wood, Peter Houghton, Angelina Vaseva
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): LB251.
https://doi.org/10.1158/1538-7445.AM2021-LB251
Published: 01 July 2021
View article titled, Abstract LB251: Vertical inhibition of the RAF MEK ERK cascade induces myogenic differentiation, apoptosis and tumor regression in H/NRAS Q61X mutant rhabdomyosarcoma
Journal Articles

Abstract 2711: Mechanism of natural progression from low grade glioma to glioblastoma: A case report

Long Wang, Xuegang Li, Tunan Chen, Feilong Zhao, Tonghui Ma, Hua Feng, Fei Li
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 2711.
https://doi.org/10.1158/1538-7445.AM2020-2711
Published: 15 August 2020
View article titled, Abstract 2711: Mechanism of natural progression from low grade glioma to glioblastoma: A case report
Journal Articles

Abstract B35: Liaison between SNAI2 and MYOD enhances oncogenesis and suppresses differentiation in fusion-negative rhabdomyosarcoma

Silvia Pomella, Prethish Sreenivas, Berkley E. Gryder, Long Wang, Matteo Cassandri, Kunal Baxi, Nicole R. Hensch, Elena Carcarino, Young Song, Marielle Yohe, Bruno Amadio, Ignazio Caruana, Cristiano De Stefanis, Rita De Vito, Franco Locatelli, Yidong Chen, Eleanor Y. Chen, Peter Houghton, Javed Khan, Rossella Rota, Myron S. Ignatius
Journal: Cancer Research
Cancer Res (2020) 80 (14_Supplement): B35.
https://doi.org/10.1158/1538-7445.PEDCA19-B35
Published: 15 July 2020
View article titled, Abstract B35: Liaison between <em>SNAI2</em> and <em>MYOD</em> enhances oncogenesis and suppresses differentiation in fusion-negative rhabdomyosarcoma
Journal Articles

Abstract 3124: SNAI2 function in embryonal RMS

Silvia Pomelo, Prethish Sreenivas, Berkley Gryder, Long Wang, Baxi Kunal, Nicole Hensch, Eleanor Chen, Peter Houghton, Rossella Rota, Javed Khan, Myron S. Ignatius
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 3124.
https://doi.org/10.1158/1538-7445.AM2019-3124
Published: 01 July 2019
View article titled, Abstract 3124: <em>SNAI2</em> function in embryonal RMS
Journal Articles

Abstract LB-064: The discovery of novel small molecular CXCR2 antagonist by using ligand-based pharmacophore model

Wen-Hai Huang, Zhi-Long Wang, Jin-Xin Che, Hai-Chao Sheng, Feng Huang, Yong-Zhou Hu, You-Hong Hu, Xin Xie, Xiao-Wu Dong
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): LB-064.
https://doi.org/10.1158/1538-7445.AM2018-LB-064
Published: 01 July 2018
View article titled, Abstract LB-064: The discovery of novel small molecular CXCR2 antagonist by using ligand-based pharmacophore model
Journal Articles

Abstract LB-288: An allosteric PRC2 inhibitor targeting the H3K27me3 binding pocket of EED

Wei Qi, Kehao Zhao, Justin Gu, Ying Huang, Youzhen Wang, Hailong Zhang, Man Zhang, Jeff Zhang, Zhengtian Yu, Ling Li, Lin Teng, Shannon Chuai, Chao Zhang, Mengxi Zhao, HoMan Chan, Zijun Chen, Douglas Fang, Fei Qi, Leying Feng, Lijian Feng, Yuan Gao, Hui Ge, Xinjian Ge, Andreas Lingel, Guobin Li, Ying Lin, Yueqin Liu, Fangjun Luo, Minlong Shi, Long Wang, Zhaofu Wang, Yanyan Yu, Jue Zeng, Chenhui Zeng, Lijun Zhang, Qiong Zhang, Shaolian Zhou, Counde Oyang, Peter Atadja, En Li
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): LB-288.
https://doi.org/10.1158/1538-7445.AM2017-LB-288
Published: 01 July 2017
View article titled, Abstract LB-288: An allosteric PRC2 inhibitor targeting the H3K27me3 binding pocket of EED
Journal Articles

Host miR155 Promotes Tumor Growth through a Myeloid-Derived Suppressor Cell–Dependent Mechanism

Siqi Chen, Long Wang, Jie Fan, Cong Ye, Donye Dominguez, Yi Zhang, Tyler J. Curiel, Deyu Fang, Timothy M. Kuzel, Bin Zhang
Journal: Cancer Research
Cancer Res (2015) 75 (3): 519–531.
https://doi.org/10.1158/0008-5472.CAN-14-2331
Published: 01 February 2015
View article titled, Host miR155 Promotes Tumor Growth through a Myeloid-Derived Suppressor Cell–Dependent Mechanism
Open the PDF for Host miR155 Promotes Tumor Growth through a Myeloid-Derived Suppressor Cell–Dependent Mechanism in another window
Includes: Supplementary data
Journal Articles

Abstract B18: Identification and characterization of NAC1 as a profilin1/actin-binding protein that is essential for effective cytokinesis in cancer cells

Kai Lee Yap, Stephanie I. Fraley, Michelle M. Thiaville, Natini Jinawath, Kentaro Nakayama, Jian-Long Wang, Denis Wirtz, Tian-Li Wang, le-Ming Shih
Journal: Cancer Research
Cancer Res (2011) 71 (18_Supplement): B18.
https://doi.org/10.1158/1538-7445.FBCR11-B18
Published: 28 October 2014
View article titled, Abstract B18: Identification and characterization of NAC1 as a profilin1/actin-binding protein that is essential for effective cytokinesis in cancer cells
Journal Articles

Abstract 1753: Comparison between early versus delayed treatment of breast cancer induced osteolytic bone metastasis by TGFβ inhibitors in a murine model

Abhik Bandyopadhyay, Joseph Agyin, Fernando Lopez-Casillas, Long Wang, Tanuka Biswas, Lu-Zhe Sun
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 1753.
https://doi.org/10.1158/1538-7445.AM2011-1753
Published: 15 April 2011
View article titled, Abstract 1753: Comparison between early versus delayed treatment of breast cancer induced osteolytic bone metastasis by TGFβ inhibitors in a murine model
Journal Articles

Abstract 2352: GSK3b can phosphorylate Slug and modulate cancer metastasis

Shih-Han Kao, Wen-Long Wang, Tse-Ming Hong, Pan-Chyr Yang
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 2352.
https://doi.org/10.1158/1538-7445.AM2011-2352
Published: 15 April 2011
View article titled, Abstract 2352: GSK3b can phosphorylate Slug and modulate cancer metastasis
Journal Articles

Extranuclear Functions of ER Impact Invasive Migration and Metastasis by Breast Cancer Cells

Dimple Chakravarty, Sujit S. Nair, Bindu Santhamma, Binoj C. Nair, Long Wang, Abhik Bandyopadhyay, Joseph K. Agyin, Darrell Brann, Lu-Zhe Sun, I-Tien Yeh, Francis Y. Lee, Rajeshwar Rao Tekmal, Rakesh Kumar, Ratna K. Vadlamudi
Journal: Cancer Research
Cancer Res (2010) 70 (10): 4092–4101.
https://doi.org/10.1158/0008-5472.CAN-09-3834
Published: 12 May 2010
View article titled, Extranuclear Functions of ER Impact Invasive Migration and Metastasis by Breast Cancer Cells
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Journal Articles

CD73 on Tumor Cells Impairs Antitumor T-Cell Responses: A Novel Mechanism of Tumor-Induced Immune Suppression

Dachuan Jin, Jie Fan, Long Wang, Linda F. Thompson, Aijie Liu, Benjamin J. Daniel, Tahiro Shin, Tyler J. Curiel, Bin Zhang
Journal: Cancer Research
Cancer Res (2010) 70 (6): 2245–2255.
https://doi.org/10.1158/0008-5472.CAN-09-3109
Published: 14 March 2010
View article titled, CD73 on Tumor Cells Impairs Antitumor T-Cell Responses: A Novel Mechanism of Tumor-Induced Immune Suppression
Open the PDF for CD73 on Tumor Cells Impairs Antitumor T-Cell Responses: A Novel Mechanism of Tumor-Induced Immune Suppression in another window
Includes: Supplementary data