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Lisa Wright
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Journal Articles

Abstract #4684: NVP-BEP800 / VER-82576: A potent orally active Hsp90 chaperone inhibitor evolved by SBDD from Vernalis fragment (\#8220;SeeDs\#8221;) hits and in silco screening hits

Paul Brough, Andrew Massey, Michael Jensen, Joseph Schoepfer, Xavier Barril, Rod Hubbard, Brian Dymock, Alan Surgenor, Lisa Wright, Bob Cozens, Sue Eccles, Swee Sharp, Flo Raynaud, Paul Workman, Carlos Garcia-Echeverria, Mike Wood, Martin Drysdale
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 4684.
Published: 01 May 2009
View article titled, Abstract #4684: NVP-BEP800 / VER-82576: A potent orally active Hsp90 chaperone inhibitor evolved by SBDD from Vernalis fragment (\#8220;SeeDs\#8221;) hits and <em>in silco</em> screening hits
Journal Articles

Inducible Cutaneous Inflammation Reveals a Protumorigenic Role for Keratinocyte CXCR2 in Skin Carcinogenesis

Christophe Cataisson, Rebecca Ohman, Gopal Patel, Andrea Pearson, Margaret Tsien, Steve Jay, Lisa Wright, Henry Hennings, Stuart H. Yuspa
Journal: Cancer Research
Cancer Res (2009) 69 (1): 319–328.
https://doi.org/10.1158/0008-5472.CAN-08-2490
Published: 31 December 2008
View article titled, Inducible Cutaneous Inflammation Reveals a Protumorigenic Role for Keratinocyte CXCR2 in Skin Carcinogenesis
Open the PDF for Inducible Cutaneous Inflammation Reveals a Protumorigenic Role for Keratinocyte CXCR2 in Skin Carcinogenesis in another window
Includes: Supplementary data
Journal Articles

NVP-AUY922: A Novel Heat Shock Protein 90 Inhibitor Active against Xenograft Tumor Growth, Angiogenesis, and Metastasis

Suzanne A. Eccles, Andy Massey, Florence I. Raynaud, Swee Y. Sharp, Gary Box, Melanie Valenti, Lisa Patterson, Alexis de Haven Brandon, Sharon Gowan, Frances Boxall, Wynne Aherne, Martin Rowlands, Angela Hayes, Vanessa Martins, Frederique Urban, Kathy Boxall, Chrisostomos Prodromou, Laurence Pearl, Karen James, Thomas P. Matthews, Kwai-Ming Cheung, Andrew Kalusa, Keith Jones, Edward McDonald, Xavier Barril, Paul A. Brough, Julie E. Cansfield, Brian Dymock, Martin J. Drysdale, Harry Finch, Rob Howes, Roderick E. Hubbard, Alan Surgenor, Paul Webb, Mike Wood, Lisa Wright, Paul Workman
Journal: Cancer Research
Cancer Res (2008) 68 (8): 2850–2860.
https://doi.org/10.1158/0008-5472.CAN-07-5256
Published: 15 April 2008
View article titled, NVP-AUY922: A Novel Heat Shock Protein 90 Inhibitor Active against Xenograft Tumor Growth, Angiogenesis, and Metastasis
Open the PDF for NVP-AUY922: A Novel Heat Shock Protein 90 Inhibitor Active against Xenograft Tumor Growth, Angiogenesis, and Metastasis in another window
Includes: Supplementary data
Journal Articles

In vitro and in vivo inhibition of the HSP90 molecular chaperone by novel, synthetic, potent pyrazole/isoxazole resorcinol 5-amide analogs

Swee Sharp, Kathy Boxall, Chrisostomos Prodromou, Marissa Powers, Joanna Holmes, Gary Box, Thomas Matthews, Kwai-Ming Cheung, Andrew Kalusa, Angela Hayes, Anthea Hardcastle, Brian Dymock, Paul Brough, Julie Cansfield, Lisa Wright, Allan Surgenor, Nicolas Foloppe, Wynne Aherne, Laurence Pearl, Keith Jones, Edward McDonald, Florence Raynaud, Sue Eccles, Martin Drysdale, Paul Workman
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 5725.
Published: 01 May 2007
View article titled, <em>In vitro </em>and <em>in vivo </em>inhibition of the HSP90 molecular chaperone by novel, synthetic, potent pyrazole/isoxazole resorcinol 5-amide analogs
Journal Articles

Microarray analysis of Ras transformed keratinocytes genetically or pharmacologically ablated for the epidermal growth factor receptor (EGFR) reveals potential alternative target pathways and off target drug effects

Lisa Wright, Andrew Ryscavage, Stuart Yuspa
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 4023.
Published: 01 May 2007
View article titled, Microarray analysis of Ras transformed keratinocytes genetically or pharmacologically ablated for the epidermal growth factor receptor (EGFR) reveals potential alternative target pathways and off target drug effects
Journal Articles

Structural comparison of inhibitor binding to Hsp90 isoforms.

Xavier Barril, Martin Drysdale, Brian Dymock, Harry Finch, Rod Hubbard, Austin Lindley, Louisa Sheridan, Allan Surgenor, Paul Workman, Lisa Wright
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 575–576.
Published: 01 April 2004
View article titled, Structural comparison of inhibitor binding to Hsp90 isoforms.
Journal Articles

Comparison of inhibitor binding to various kinases.

Steven Athwal, I-Jen Chen, Pawel Dokurno, Mhairi Donohoe, Martin Drysdale, Harry Finch, Nicolas Foloppe, Rob Howes, Rod Hubbard, Austin Lindley, Christine Richardson, Alan Robertson, Louisa Sheridan, Chris Torrance, Stephen Walker, Lisa Wright
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 574.
Published: 01 April 2004
View article titled, Comparison of inhibitor binding to various kinases.