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Journal Articles

Abstract 2108: Comparative analysis of fusion gene detection rates in tissue versus blood samples from Chinese diverse solid tumors

Jun-Ling Wang, Hong-Wei Li, Hong-Xia Liu, Xiu-Ping Li, Jian-Peng Hu, Qian Xiong, Jin-Si Yang, Zong-Sheng Wu, Ting Ji

Cancer Res (2025) 85 (8_Supplement_1): 2108.

https://doi.org/10.1158/1538-7445.AM2025-2108

Published: 21 April 2025

View articletitled, Abstract 2108: Comparative analysis of fusion gene detection rates in tissue versus blood samples from Chinese diverse solid tumors

Journal Articles

Abstract 2188: Enabling sensitivity, repeatability and reproducibility required for immuno-oncology research on the CyTOF XT Pro mass cytometer

Stephen Li, Rita Straus, Michael Sullivan, Andrea McEwan, Ling Wang, Christina Loh, Alexander Loboda

Cancer Res (2025) 85 (8_Supplement_1): 2188.

https://doi.org/10.1158/1538-7445.AM2025-2188

Published: 21 April 2025

View articletitled, Abstract 2188: Enabling sensitivity, repeatability and reproducibility required for immuno-oncology research on the CyTOF XT Pro mass cytometer

Journal Articles

Abstract 3195: Advancing CAR T clinical development with high-parameter CyTOF technology

Ling Wang, Shakir Hasan, Stephen Li, Michael Cohen, Deeqa Mahamed, Christina Loh

Cancer Res (2025) 85 (8_Supplement_1): 3195.

https://doi.org/10.1158/1538-7445.AM2025-3195

Published: 21 April 2025

View articletitled, Abstract 3195: Advancing CAR T clinical development with high-parameter CyTOF technology

Journal Articles

Abstract 7122: Accelerating immuno-oncology research with flexible workflows using modular flex-fit CyTOF panels

Shakir Hasan, Ling Wang, Stephen Li, Christina Loh

Cancer Res (2025) 85 (8_Supplement_1): 7122.

https://doi.org/10.1158/1538-7445.AM2025-7122

Published: 21 April 2025

View articletitled, Abstract 7122: Accelerating immuno-oncology research with flexible workflows using modular flex-fit CyTOF panels

Journal Articles

Abstract 5450: JSKN022, a first in class multi-specific ADC targeting PD-L1 and ITGB6/8 with an innovative DNA topoisomerase I inhibitor demonstrates encouraging efficacy in preclinical models

Ting Xu, Ling Wang, Yongli Dong, Chuankun Shan

Cancer Res (2025) 85 (8_Supplement_1): 5450.

https://doi.org/10.1158/1538-7445.AM2025-5450

Published: 21 April 2025

View articletitled, Abstract 5450: JSKN022, a first in class multi-specific ADC targeting PD-L1 and ITGB6/8 with an innovative DNA topoisomerase I inhibitor demonstrates encouraging efficacy in preclinical models

Journal Articles

Abstract 5755: Expansion of the known functional diversity of human T cells achieved due to the unprecedented resolution of intracellular proteins by mass cytometry (CyTOF)

Laura Polanco, Michael J. Cohen, Erika L. Smith-Mahoney, Ling Wang, David King, Madison Bailey, Christina Loh, Anna C. Belkina, Amedeo J. Cappione, Jennifer E. Snyder-Cappione

Cancer Res (2025) 85 (8_Supplement_1): 5755.

https://doi.org/10.1158/1538-7445.AM2025-5755

Published: 21 April 2025

View articletitled, Abstract 5755: Expansion of the known functional diversity of human T cells achieved due to the unprecedented resolution of intracellular proteins by mass cytometry (CyTOF)

Journal Articles

Analysis of Tumor-Associated AXIN1 Missense Mutations Identifies Variants That Activate β-Catenin Signaling

Ruyi Zhang, Shanshan Li, Kelly Schippers, Yunlong Li, Boaz Eimers, Marla Lavrijsen, Ling Wang, Guofei Cui, Xin Chen, Maikel P. Peppelenbosch, Joyce H.G. Lebbink, Ron Smits

Cancer Res (2024) 84 (9): 1443–1459.

https://doi.org/10.1158/0008-5472.CAN-23-2268

Published: 02 May 2024

View articletitled, Analysis of Tumor-Associated AXIN1 Missense Mutations Identifies Variants That Activate β-Catenin Signaling

Includes: Supplementary data

Journal Articles

Abstract 4514: Discovery of potent and orally bioavailable degraders of HPK1 based on a novel HPK1 binder

Zhimin Zhang, Mengqiang Wu, Ling Wang, Xi Yang, Zhiping Zhang, Liubin Guo, Hao Pan, Mengting Zhao, Linli Wang, Sirui Liu, Zhao Dong, Chunhua Jiang, Haowen Zheng, Dongzhou Liu

Cancer Res (2024) 84 (6_Supplement): 4514.

https://doi.org/10.1158/1538-7445.AM2024-4514

Published: 22 March 2024

View articletitled, Abstract 4514: Discovery of potent and orally bioavailable degraders of HPK1 based on a novel HPK1 binder

Journal Articles

Abstract 249: Deciphering the impact of TRIB3-ELF4 interaction in regulating CDK6 on cancer stem cell activity in endometrial cancer

Wen-Ling Wang, Wen-Wei Chang

Cancer Res (2024) 84 (6_Supplement): 249.

https://doi.org/10.1158/1538-7445.AM2024-249

Published: 22 March 2024

View articletitled, Abstract 249: Deciphering the impact of TRIB3-ELF4 interaction in regulating CDK6 on cancer stem cell activity in endometrial cancer

Journal Articles

Abstract 1656: ISM6331, a novel and potent pan-TEAD inhibitor, exhibits strong anti-tumor activity in preclinical models of Hippo pathway-dysregulated cancers

Qi Li, Jainfei Wan, Jinxin Liu, Jing Shang, Jiaojiao Yu, Wei Zhu, Celia X.-J. Chen, Junwen Qiao, Ling Wang, Man Zhang, Xiao Ding, Supriya Bavadekar, Sujata Rao, Feng Ren, Alex Zhavoronkov

Cancer Res (2024) 84 (6_Supplement): 1656.

https://doi.org/10.1158/1538-7445.AM2024-1656

Published: 22 March 2024

View articletitled, Abstract 1656: ISM6331, a novel and potent pan-TEAD inhibitor, exhibits strong anti-tumor activity in preclinical models of Hippo pathway-dysregulated cancers

Journal Articles

LILRB3 Modulates Acute Myeloid Leukemia Progression and Acts as an Effective Target for CAR T-cell Therapy

Cancer Res (2023) 83 (24): 4047–4062.

https://doi.org/10.1158/0008-5472.CAN-22-2483

Published: 15 December 2023

View articletitled, LILRB3 Modulates Acute Myeloid Leukemia Progression and Acts as an Effective Target for CAR T-cell Therapy

Includes: Supplementary data

Journal Articles

Abstract 502: ISM3091, a novel selective USP1 inhibitor as a targeted anticancer therapy

Yangguang Li, Jianping Wu, Jinxin Liu, Luoheng Qin, Xin Cai, Junwen Qiao, Ling Wang, Sujata Rao, Feng Ren, Alex Zhavoronkov

Cancer Res (2023) 83 (7_Supplement): 502.

https://doi.org/10.1158/1538-7445.AM2023-502

Published: 04 April 2023

View articletitled, Abstract 502: ISM3091, a novel selective USP1 inhibitor as a targeted anticancer therapy

Journal Articles

Abstract 1773: Preclinical characterization of allogeneic Vγ9Vδ2 HER2-TAC T cells for the treatment of HER2-positive solid tumors

Suzanna L. Prosser, Stacey X. Xu, Ling Wang, Ritu R. Randhawa, Sailaja Pirati, Laura Ravensbergen, Seungmi Yoo, Miyoung Jung, Laurentia Gheorghiu, Angel Gomez, Gurleen Sandhu, Chris Ayers, Donna Rill, Christopher W. Helsen, Andreas G. Bader

Cancer Res (2023) 83 (7_Supplement): 1773.

https://doi.org/10.1158/1538-7445.AM2023-1773

Published: 04 April 2023

View articletitled, Abstract 1773: Preclinical characterization of allogeneic Vγ9Vδ2 HER2-TAC T cells for the treatment of HER2-positive solid tumors

Journal Articles

Abstract 503: ISM3412, a novel and selective MAT2A inhibitor for the treatment of cancer

Qingyuan Meng, Xiao Ding, Xiaosong Liu, Hailong Wang, Ling Wang, Junwen Qiao, Hua Cao, Yushu Yin, Congcong Zhu, Xing Liang, Xin Cai, Yuanyuan Xu, Chenxi Xu, Shan Chen, Sujata Rao, Feng Ren, Alex Zhavoronkov

Cancer Res (2023) 83 (7_Supplement): 503.

https://doi.org/10.1158/1538-7445.AM2023-503

Published: 04 April 2023

View articletitled, Abstract 503: ISM3412, a novel and selective MAT2A inhibitor for the treatment of cancer

Journal Articles

Abstract 6123: Characterization of the synergistic tumor cytotoxicity of agonistic DR5 IgM antibody IGM-8444 with chemotherapeutic agents

Beatrice T. Wang, Thomas J. Matthew, Poonam Yakkundi, Miho Oyasu, Mélanie Desbois, Susan E. Calhoun, Ling Wang, Tasnim Kothambawala, Devinder K. Ubhi, Marvin S. Peterson, Eric W. Humke, Maya F. Kotturi, Bruce A. Keyt, Angus M. Sinclair

Cancer Res (2023) 83 (7_Supplement): 6123.

https://doi.org/10.1158/1538-7445.AM2023-6123

Published: 04 April 2023

View articletitled, Abstract 6123: Characterization of the synergistic tumor cytotoxicity of agonistic DR5 IgM antibody IGM-8444 with chemotherapeutic agents

Journal Articles

Abstract 2933: Novel CD123xCD3 bispecific IgM antibody, IGM-2537, potently induces T-cell mediated cytotoxicity of acute myeloid leukemia cells with minimal cytokine release

Gene Li, Ling Wang, Poonam Yakkundi, Paul Hinton, Deepal Pandya, Keerthana Sekar, Rodine Rosete, Zhongde Ye, Nardeen Hanna, Maya F. Kotturi, Liz Bogaert, Jiyoung Hong, Christina Tsai, Thomas Manley, Bruce A. Keyt, Angus M. Sinclair, Liqin Liu

Cancer Res (2023) 83 (7_Supplement): 2933.

https://doi.org/10.1158/1538-7445.AM2023-2933

Published: 04 April 2023

View articletitled, Abstract 2933: Novel CD123xCD3 bispecific IgM antibody, IGM-2537, potently induces T-cell mediated cytotoxicity of acute myeloid leukemia cells with minimal cytokine release

Journal Articles

Abstract 3188: Patient-derived TAC01-HER2 TAC T cells produced in Cocoon® Platform is highly functional in models of solid tumors

Ling Wang, Stacey X. Xu, Tania Benatar, Ritu R. Randhawa, Philbert Ip, Prabha Lal, Thanyashanthi Nitya-Nootan, Laura Ravensbergen, Heather MacGregor, Suzy Prosser, Sadhak Sengupta, Christopher W. Helsen, Andreas G. Bader

Cancer Res (2023) 83 (7_Supplement): 3188.

https://doi.org/10.1158/1538-7445.AM2023-3188

Published: 04 April 2023

View articletitled, Abstract 3188: Patient-derived TAC01-HER2 TAC T cells produced in Cocoon® Platform is highly functional in models of solid tumors

Journal Articles

Abstract 572: Pre-clinical evaluation of Claudin 18.2 TAC T cells for the treatment of gastric cancer

Tania Benatar, Ling Wang, Thanyashanthi Nitya-Nootan, Heather MacGregor, Suzanna Prosser, Philbert Ip, Prabha Lal, Laura Shaver, Sadhak Sengupta, Christopher W. Helsen, Andreas G. Bader

Cancer Res (2022) 82 (12_Supplement): 572.

https://doi.org/10.1158/1538-7445.AM2022-572

Published: 15 June 2022

View articletitled, Abstract 572: Pre-clinical evaluation of Claudin 18.2 TAC T cells for the treatment of gastric cancer

Journal Articles

Abstract 1792: FGFR3 mediated PARP1 tyrosine 158 phosphorylation promotes PARP inhibitor resistance

Cancer Res (2022) 82 (12_Supplement): 1792.

https://doi.org/10.1158/1538-7445.AM2022-1792

Published: 15 June 2022

View articletitled, Abstract 1792: FGFR3 mediated PARP1 tyrosine 158 phosphorylation promotes PARP inhibitor resistance

Journal Articles

Abstract 1068: Anti-DR5 agonist IgM antibody IGM-8444 combined with SMAC mimetic birinapant induces strong synergistic tumor cytotoxicity

Beatrice T. Wang, Melanie Desbois, Susan E. Calhoun, Thomas J. Matthew, Poonam Yakkundi, Ling Wang, Xingjie Chen, Tasnim Kothambawala, Miho Oyasu, Maya F. Kotturi, Genevive Hernandez, Xiaohan Liu, Marvin S. Peterson, Eric W. Humke, Bruce A. Keyt, Angus M. Sinclair

Cancer Res (2022) 82 (12_Supplement): 1068.

https://doi.org/10.1158/1538-7445.AM2022-1068

Published: 15 June 2022

View articletitled, Abstract 1068: Anti-DR5 agonist IgM antibody IGM-8444 combined with SMAC mimetic birinapant induces strong synergistic tumor cytotoxicity

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Abstract 2108: Comparative analysis of fusion gene detection rates in tissue versus blood samples from Chinese diverse solid tumors

Abstract 2188: Enabling sensitivity, repeatability and reproducibility required for immuno-oncology research on the CyTOF XT Pro mass cytometer

Abstract 3195: Advancing CAR T clinical development with high-parameter CyTOF technology

Abstract 7122: Accelerating immuno-oncology research with flexible workflows using modular flex-fit CyTOF panels

Abstract 5450: JSKN022, a first in class multi-specific ADC targeting PD-L1 and ITGB6/8 with an innovative DNA topoisomerase I inhibitor demonstrates encouraging efficacy in preclinical models

Abstract 5755: Expansion of the known functional diversity of human T cells achieved due to the unprecedented resolution of intracellular proteins by mass cytometry (CyTOF)

Analysis of Tumor-Associated AXIN1 Missense Mutations Identifies Variants That Activate β-Catenin Signaling

Abstract 4514: Discovery of potent and orally bioavailable degraders of HPK1 based on a novel HPK1 binder

Abstract 249: Deciphering the impact of TRIB3-ELF4 interaction in regulating CDK6 on cancer stem cell activity in endometrial cancer

Abstract 1656: ISM6331, a novel and potent pan-TEAD inhibitor, exhibits strong anti-tumor activity in preclinical models of Hippo pathway-dysregulated cancers

LILRB3 Modulates Acute Myeloid Leukemia Progression and Acts as an Effective Target for CAR T-cell Therapy

Abstract 502: ISM3091, a novel selective USP1 inhibitor as a targeted anticancer therapy

Abstract 1773: Preclinical characterization of allogeneic Vγ9Vδ2 HER2-TAC T cells for the treatment of HER2-positive solid tumors

Abstract 503: ISM3412, a novel and selective MAT2A inhibitor for the treatment of cancer

Abstract 6123: Characterization of the synergistic tumor cytotoxicity of agonistic DR5 IgM antibody IGM-8444 with chemotherapeutic agents

Abstract 2933: Novel CD123xCD3 bispecific IgM antibody, IGM-2537, potently induces T-cell mediated cytotoxicity of acute myeloid leukemia cells with minimal cytokine release

Abstract 3188: Patient-derived TAC01-HER2 TAC T cells produced in Cocoon® Platform is highly functional in models of solid tumors

Abstract 572: Pre-clinical evaluation of Claudin 18.2 TAC T cells for the treatment of gastric cancer

Abstract 1792: FGFR3 mediated PARP1 tyrosine 158 phosphorylation promotes PARP inhibitor resistance

Abstract 1068: Anti-DR5 agonist IgM antibody IGM-8444 combined with SMAC mimetic birinapant induces strong synergistic tumor cytotoxicity

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