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Lindy G. Durrant
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Journal Articles

Abstract CT256: Modi-1, anti-citrullinated neoepitope vaccine alone and combined with checkpoint inhibitors in patients with head and neck, breast, renal and ovarian carcinoma: protocol for the ModiFY phase I/II basket clinical Ttial

Lindy G. Durrant, Fayaz Masters, Samantha Paston, Robert Miller, David J. Pinato, Rebecca Herbertson, Anne Armstrong, Stefan Symeonides, Christian Ottensmeier
Journal: Cancer Research
Cancer Res (2023) 83 (8_Supplement): CT256.
https://doi.org/10.1158/1538-7445.AM2023-CT256
Published: 14 April 2023
View article titled, Abstract CT256: Modi-1, anti-citrullinated neoepitope vaccine alone and combined with checkpoint inhibitors in patients with head and neck, breast, renal and ovarian carcinoma: protocol for the ModiFY phase I/II basket clinical Ttial
Journal Articles

Engineering the Human Fc Region Enables Direct Cell Killing by Cancer Glycan–Targeting Antibodies without the Need for Immune Effector Cells or Complement

Mireille Vankemmelbeke, Richard S. McIntosh, Jia Xin Chua, Thomas Kirk, Ian Daniels, Marilena Patsalidou, Robert Moss, Tina Parsons, David Scott, Gemma Harris, Judith M. Ramage, Ian Spendlove, Lindy G. Durrant
Journal: Cancer Research
Series: Author Choice
Cancer Res (2020) 80 (16): 3399–3412.
https://doi.org/10.1158/0008-5472.CAN-19-3599
Published: 14 August 2020
View article titled, Engineering the Human Fc Region Enables Direct Cell Killing by Cancer Glycan–Targeting Antibodies without the Need for Immune Effector Cells or Complement
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Includes: Supplementary data
Journal Articles

Citrullinated Vimentin Presented on MHC-II in Tumor Cells Is a Target for CD4+ T-Cell–Mediated Antitumor Immunity

Victoria A. Brentville, Rachael L. Metheringham, Barbara Gunn, Peter Symonds, Ian Daniels, Mohamed Gijon, Katherine Cook, Wei Xue, Lindy G. Durrant
Journal: Cancer Research
Series: Author Choice
Cancer Res (2016) 76 (3): 548–560.
https://doi.org/10.1158/0008-5472.CAN-15-1085
Published: 31 January 2016
View article titled, Citrullinated Vimentin Presented on MHC-II in Tumor Cells Is a Target for CD4<sup>+</sup> T-Cell–Mediated Antitumor Immunity
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Includes: Supplementary data
Journal Articles

Abstract 1348: CD4 T cells targeting citrullinated vimentin reject advanced tumors

Lindy G. Durrant, Victoria A. Brentville, Rachael L. Metheringham, Ian Daniels, Peter Symonds, Mohamed Gijon, Wei Xue
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 1348.
https://doi.org/10.1158/1538-7445.AM2015-1348
Published: 01 August 2015
View article titled, Abstract 1348: CD4 T cells targeting citrullinated vimentin reject advanced tumors
Journal Articles

Abstract CT331: Phase I/II trial of a novel antibody DNA immunotherapy, targeting CD64, in the treatment of Melanoma

Lindy G. Durrant, Christian H. Ottensmeier, Paul Lorigan, Clive Mulatero, Ruth Plummer, Michelle Cunell, Rachael Metheringham, Victoria Brentville, Lee Machado, Poulam Patel
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): CT331.
https://doi.org/10.1158/1538-7445.AM2014-CT331
Published: 01 October 2014
View article titled, Abstract CT331: Phase I/II trial of a novel antibody DNA immunotherapy, targeting CD64, in the treatment of Melanoma
Journal Articles

Abstract 2402: Stimulation of high avidity T cell responses are an essential pre-requisite for a cancer vaccine

Lindy G. Durrant, Victoria Pudney, Barbra Gunn, Ian Spendlove, Rachael L. Metheringham
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 2402.
https://doi.org/10.1158/1538-7445.AM10-2402
Published: 15 April 2010
View article titled, Abstract 2402: Stimulation of high avidity T cell responses are an essential pre-requisite for a cancer vaccine
Journal Articles

A New Anticancer Glycolipid Monoclonal Antibody, SC104, which Directly Induces Tumor Cell Apoptosis

Lindy G. Durrant, Stephen J. Harding, Nicola H. Green, Lorraine D. Buckberry, Tina Parsons
Journal: Cancer Research
Cancer Res (2006) 66 (11): 5901–5909.
https://doi.org/10.1158/0008-5472.CAN-05-3812
Published: 01 June 2006
View article titled, A New Anticancer Glycolipid Monoclonal Antibody, SC104, which Directly Induces Tumor Cell Apoptosis
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Journal Articles

Prognostic significance of SC101, a monoclonal Antibody against Lewisy/b in breast tumors

Zahra Madjd, Ian Spendlove, Ian Ellis, Tina Parsons, Lindy G. Durrant
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 360–361.
Published: 01 May 2005
View article titled, Prognostic significance of SC101, a monoclonal Antibody against Lewis<sup>y/b</sup> in breast tumors
Journal Articles

Loss of MHC Class I is an independent indicator of good prognosis in breast cancer

Zahra Madjd, Ian Spendlove, Sarah E. Pinder, Ian O. Ellis, Lindy G. Durrant
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 1424.
Published: 01 May 2005
View article titled, Loss of MHC Class I is an independent indicator of good prognosis in breast cancer
Journal Articles

Prognostic significance of membrane cofactor protein (CD46) on breast tumors.

Zahra Madjd, Ian Spendlove, Sarah E. Pinder, Neil K. Rushmere, B. Paul Morgan, Lindy G. Durrant
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 506.
Published: 01 April 2004
View article titled, Prognostic significance of membrane cofactor protein (CD46) on breast tumors.
Journal Articles

A Tie-2 DNA vaccine targeting tumor endothelium

Judith M. Ramage, Ian Spendlove, Rachael Metheringham, Robert S. Moss, Selman Ali, Peter Hewett, Lindy G. Durrant
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 1119.
Published: 01 April 2004
View article titled, A Tie-2 DNA vaccine targeting tumor endothelium
Journal Articles

Vaccine-induced Apoptosis: A Novel Clinical Trial End Point?

Schwann Amin, R. Adrian Robins, Charles A. Maxwell-Armstrong, John H. Scholefield, Lindy G. Durrant
Journal: Cancer Research
Cancer Res (2000) 60 (12): 3132–3136.
Published: 15 June 2000
View article titled, Vaccine-induced Apoptosis: A Novel Clinical Trial End Point?
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Journal Articles

Decay Accelerating Factor (CD55): A Target for Cancer Vaccines?

Ian Spendlove, Li Li, James Carmichael, Lindy G. Durrant
Journal: Cancer Research
Cancer Res (1999) 59 (10): 2282–2286.
Published: 15 May 1999
View article titled, Decay Accelerating Factor (CD55): <subtitle>A Target for Cancer Vaccines?</subtitle>
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Journal Articles

Antitumor Immune Response and Interleukin 2 Production Induced in Colorectal Cancer Patients by Immunization with Human Monoclonal Anti-Idiotypic Antibody

R. Adrian Robins, Gavin W. L. Denton, Jack D. Hardcastle, Eric B. Austin, Robert W. Baldwin, Lindy G. Durrant
Journal: Cancer Research
Cancer Res (1991) 51 (19): 5425–5429.
Published: 01 October 1991
View article titled, Antitumor Immune Response and Interleukin 2 Production Induced in Colorectal Cancer Patients by Immunization with Human Monoclonal Anti-Idiotypic Antibody
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Journal Articles

Association of Antigen Expression and DNA Ploidy in Human Colorectal Tumors

Lindy G. Durrant, R. Adrian Robins, Nicholas C. Armitage, Anthony Brown, Robert W. Baldwin, Jack D. Hardcastle
Journal: Cancer Research
Cancer Res (1986) 46 (7): 3543–3549.
Published: 01 July 1986
View article titled, Association of Antigen Expression and DNA Ploidy in Human Colorectal Tumors
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