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Linda Clipson
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Journal Articles

Abstract 3842: Versican proteolysis is a predictive biomarker of tumor infiltrating lymphocytes within primary and metastatic colorectal cancer tumors

Sean G. Kraus, Kristina A. Matkowskyj, Philip B. Emmerich, Wei Zhang, Linda Clipson, Cheri A. Pasch, Dustin A. Deming
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 3842.
https://doi.org/10.1158/1538-7445.AM2022-3842
Published: 15 June 2022
View article titled, Abstract 3842: Versican proteolysis is a predictive biomarker of tumor infiltrating lymphocytes within primary and metastatic colorectal cancer tumors
Journal Articles

Abstract 3721: MTORC1/2 and HDAC1/2 inhibition as therapy for colorectal cancer with PIK3CA mutation

Autumn M. Olson, Rebecca A. DeStefanis, Alyssa K. DeZeeuw, Susan N. Payne, Cheri A. Pasch, Linda Clipson, Dustin A. Deming
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 3721.
https://doi.org/10.1158/1538-7445.AM2022-3721
Published: 15 June 2022
View article titled, Abstract 3721: MTORC1/2 and HDAC1/2 inhibition as therapy for colorectal cancer with PIK3CA mutation
Journal Articles

Abstract 3198: Validation and analysis of cancer associated fibroblast subtype markers in metastatic colorectal cancer

Anna L. Lippert, Katherine A. Johnson, Cheri A. Pasch, Sean G. Kraus, Philip B. Emmerich, Linda Clipson, Kristina A. Matkowskyj, Wei Zhang, Dustin A. Deming
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 3198.
https://doi.org/10.1158/1538-7445.AM2022-3198
Published: 15 June 2022
View article titled, Abstract 3198: Validation and analysis of cancer associated fibroblast subtype markers in metastatic colorectal cancer
Journal Articles

Abstract 3533: Effects of tyrosine kinase inhibitors imatinib, dasatinib, and nilotinib on cancer-associated fibroblast phenotypes in colorectal cancer

Katherine Anne Johnson, Anna L. Lippert, Sean G. Kraus, Grace E. McGrath, Philip B. Emmerich, Cheri A. Pasch, Linda Clipson, Kristina A. Matkowskyj, Wei Zhang, Dustin A. Deming
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 3533.
https://doi.org/10.1158/1538-7445.AM2022-3533
Published: 15 June 2022
View article titled, Abstract 3533: Effects of tyrosine kinase inhibitors imatinib, dasatinib, and nilotinib on cancer-associated fibroblast phenotypes in colorectal cancer
Journal Articles

Abstract 1128: MTORC1/2 and HDAC1/2 inhibition promote tumor response through inhibition of MYC

Rebecca A. DeStefanis, Autumn M. Olson, Alyssa K. DeZeeuw, Susan N. Payne, Cheri A. Pasch, Linda Clipson, Dustin A. Deming
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 1128.
https://doi.org/10.1158/1538-7445.AM2022-1128
Published: 15 June 2022
View article titled, Abstract 1128: MTORC1/2 and HDAC1/2 inhibition promote tumor response through inhibition of MYC
Journal Articles

Abstract 2673: Combined inhibition of PI3K and HDAC1/2 as a novel treatment strategy for RAS/RAF wildtype colorectal cancer in a patient derived organoid model

Alyssa K. DeZeeuw, Rebecca A. DeStefanis, Susan N. Payne, Autumn M. Olson, Cheri A. Pasch, Linda Clipson, Dustin A. Deming
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 2673.
https://doi.org/10.1158/1538-7445.AM2022-2673
Published: 15 June 2022
View article titled, Abstract 2673: Combined inhibition of PI3K and HDAC1/2 as a novel treatment strategy for RAS/RAF wildtype colorectal cancer in a patient derived organoid model
Journal Articles

Abstract 2734: Impact of the mutation profile and versican status on lymphocyte infiltration in early age onset colorectal cancer

Katherine A. Johnson, Philip B. Emmerich, Anna L. Lippert, Cheri A. Pasch, Linda Clipson, Wei Zhang, Kristina A. Matkowskyj, Dustin A. Deming
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2734.
https://doi.org/10.1158/1538-7445.AM2021-2734
Published: 01 July 2021
View article titled, Abstract 2734: Impact of the mutation profile and versican status on lymphocyte infiltration in early age onset colorectal cancer
Journal Articles

Abstract 1944: Navitoclax enhances the efficacy of copanlisib predominantly through inhibition of BCLxL in PIK3CA mutant colorectal cancer

Rebecca Anna DeStefanis, Alyssa DeZeeuw, Gioia Sha, Autumn Olson, Samantha J. Anderson, Christopher P. Babiarz, Cheri A. Pasch, Linda Clipson, Dustin A. Deming
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 1944.
https://doi.org/10.1158/1538-7445.AM2021-1944
Published: 01 July 2021
View article titled, Abstract 1944: Navitoclax enhances the efficacy of copanlisib predominantly through inhibition of BCLxL in <em>PIK3CA</em> mutant colorectal cancer
Journal Articles

Abstract 2969: Impact of baseline culture condition on the growth and treatment response of mouse derived cancer organoids

Autumn Olson, Rebecca A. DeStefanis, Alyssa DeZeeuw, Samantha Anderson, Gioia Sha, Jeremy Kratz, Cheri Pasch, Linda Clipson, Dustin A. Deming
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2969.
https://doi.org/10.1158/1538-7445.AM2021-2969
Published: 01 July 2021
View article titled, Abstract 2969: Impact of baseline culture condition on the growth and treatment response of mouse derived cancer organoids
Journal Articles

Abstract 3166: Impact of cancer associated fibroblast phenotypes on the infiltration of t-lymphocytes in early age onset colorectal cancer

Anna Lippert, Katherine A. Johnson, Philip B. Emmerich, Cheri A. Pasch, Linda Clipson, Kristina A. Matkowskyi, Wei Zhang, Dustin A. Deming
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 3166.
https://doi.org/10.1158/1538-7445.AM2021-3166
Published: 01 July 2021
View article titled, Abstract 3166: Impact of cancer associated fibroblast phenotypes on the infiltration of t-lymphocytes in early age onset colorectal cancer
Journal Articles

Abstract 3048: Murine-derived colorectal cancer organoid culture high-throughput drug screening to identify novel combinations targeting PIK3CA mutant cancers

Alyssa K. DeZeeuw, Rebecca A. DeStefanis, Gioia Sha, Cheri A. Pasch, Linda Clipson, Dustin A. Deming
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 3048.
https://doi.org/10.1158/1538-7445.AM2020-3048
Published: 15 August 2020
View article titled, Abstract 3048: Murine-derived colorectal cancer organoid culture high-throughput drug screening to identify novel combinations targeting <em>PIK3CA</em> mutant cancers
Journal Articles

Abstract 3294: PD-L1 status and versican proteolysis predict CD8+ T cell infiltration in esophageal cancer

Phillip B. Emmerich, Jacob Witt, Darya Buehler, Mitchell Depke, Nathaniel Verhagen, Linda Clipson, Kristina Matkowskyj, Nataliya Uboha, Andrew Baschnagel, Dustin Deming
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 3294.
https://doi.org/10.1158/1538-7445.AM2020-3294
Published: 15 August 2020
View article titled, Abstract 3294: PD-L1 status and versican proteolysis predict CD8<sup>+</sup> T cell infiltration in esophageal cancer
Journal Articles

Abstract 2701: Patient-derived colorectal cancer organoid therapeutic escalation: Tracking resistance to EGFR inhibition for predicting therapeutic sensitivity

Jeremy D. Kratz, Aishwarya Sunil, Meghan Conroy, Cheri A. Pasch, Nicole Lassen, Hannah Houtler, Kayla K. Lemmon, Linda Clipson, Daniel E. Abbott, Evie H. Carchman, Elise H. Lawson, Noelle K. Loconte, Sam J. Lubner, Kristina A. Matkowskyj, Daniel L. Mulkerin, Nataliya Uboha, Dustin A. Deming
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 2701.
https://doi.org/10.1158/1538-7445.AM2020-2701
Published: 15 August 2020
View article titled, Abstract 2701: Patient-derived colorectal cancer organoid therapeutic escalation: Tracking resistance to EGFR inhibition for predicting therapeutic sensitivity
Journal Articles

Abstract 1494: Etiologies of patient-derived colorectal cancer organoid growth heterogeneity across multiple patient samples and culture conditions

Aishwarya Sunil, Jeremy D. Kratz, Sarbjeet K. Makkar, Suhjah Rehman, Amani A. Gillette, Katherine A. Johnson, Cheri A. Pasch, Linda Clipson, Kristina A. Matkowskyj, Melissa C. Skala, Dustin A. Deming
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 1494.
https://doi.org/10.1158/1538-7445.AM2020-1494
Published: 15 August 2020
View article titled, Abstract 1494: Etiologies of patient-derived colorectal cancer organoid growth heterogeneity across multiple patient samples and culture conditions
Journal Articles

Abstract 5102: Gemcitabine and nab-paclitaxel increase immunosuppressive environment in PDAC

Hanna R. Rainiero, Philip B. Emmerich, Nathaniel Verhagen, Rebecca Destefanis, Cheri A. Pasch, Linda Clipson, Kristina A. Matkowskyj, Dustin A. Deming
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 5102.
https://doi.org/10.1158/1538-7445.AM2020-5102
Published: 15 August 2020
View article titled, Abstract 5102: Gemcitabine and nab-paclitaxel increase immunosuppressive environment in PDAC
Journal Articles

Abstract 5110: Cancer-associated fibroblast phenotypes vary across colorectal cancers and correlate with CD8+ T-cell infiltration

Katherine A. Johnson, Philip B. Emmerich, Cheri A. Pasch, Linda Clipson, Kristina A. Matkowskyj, Dustin A. Deming
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 5110.
https://doi.org/10.1158/1538-7445.AM2020-5110
Published: 15 August 2020
View article titled, Abstract 5110: Cancer-associated fibroblast phenotypes vary across colorectal cancers and correlate with CD8+ T-cell infiltration
Journal Articles

Abstract 75: BCL-xL inhibition enhances therapeutic response of MTORC1/2 inhibition and induction of apoptosis in PIK3CA mutant colorectal cancer

Rebecca A. DeStefanis, Alyssa DeZeeuw, Gioia Sha, Susan N. Payne, Christopher P. Babiarz, Devon Miller, Demetra K. Korkos, Cheri A. Pasch, Linda Clipson, Kristina Matkowskyj, Dustin A. Deming
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 75.
https://doi.org/10.1158/1538-7445.AM2020-75
Published: 15 August 2020
View article titled, Abstract 75: BCL-xL inhibition enhances therapeutic response of MTORC1/2 inhibition and induction of apoptosis in <em>PIK3CA</em> mutant colorectal cancer
Journal Articles

Abstract 1909: Stromal cell driven proteolysis of versican is limited by epithelial cells in pancreatic ductal adenocarcinoma

Philip B. Emmerich, Chelsie Sievers, Hanna Rainiero, Rosabella Pitera, Connor Maloney, Susan Payne, Mitchell Depke, Cheri Pasch, Linda Clipson, Jillian K. Johnson, Kristina Matkowskyj, Fotis Asimakopoulos, Dustin A. Deming
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 1909.
https://doi.org/10.1158/1538-7445.AM2019-1909
Published: 01 July 2019
View article titled, Abstract 1909: Stromal cell driven proteolysis of versican is limited by epithelial cells in pancreatic ductal adenocarcinoma
Journal Articles

Abstract 1904: Versican production is driven by both epithelial and stromal cells in pancreatic cancer

Hanna R. Rainiero, Philip B. Emmerich, Chelsie K. Sievers, Connor J. Maloney, Rosabella T. Pitera, Susan N. Payne, Mitchell G. Depke, Cheri A. Pasch, Linda Clipson, Jillian K. Johnson, Kristina A. Matkowskyj, Fotis Asimakopoulos, Dustin A. Deming
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 1904.
https://doi.org/10.1158/1538-7445.AM2019-1904
Published: 01 July 2019
View article titled, Abstract 1904: Versican production is driven by both epithelial and stromal cells in pancreatic cancer
Journal Articles

Abstract 3209: BLZ945 and anti-PD-1 combination immunotherapy modulates the immune landscape in pancreatic ductal adenocarcinoma

Chelsie K. Sievers, Philip B. Emmerich, Hanna R. Rainiero, Connor Maloney, Rosabella Pitera, Cheri A. Pasch, Linda Clipson, Kristina A. Matkowskyj, Fotis Asimakopoulos, Dustin A. Deming
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 3209.
https://doi.org/10.1158/1538-7445.AM2019-3209
Published: 01 July 2019
View article titled, Abstract 3209: BLZ945 and anti-PD-1 combination immunotherapy modulates the immune landscape in pancreatic ductal adenocarcinoma