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Journal Articles

Abstract LB174: REST-USP37 axis controls GLI1 levels in sonic hedgehog medulloblastoma cells

Free
Ashutosh Singh, Donghang Cheng, Lei Guo, Amanda Haltom, Tara Dobson, Veena Rajaram, Lin Xu, Vidya Gopalakrishnan
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_2): LB174.
https://doi.org/10.1158/1538-7445.AM2025-LB174
Published: 25 April 2025
View articletitled, Abstract LB174: REST-USP37 axis controls GLI1 levels in sonic hedgehog medulloblastoma cells
Journal Articles

CLK1 Activates YAP to Promote Intrahepatic Cholangiocarcinogenesis

Available to Purchase
Shuai Xue, Xiangzheng Chen, Guoteng Qiu, Haotian Liao, Zeyuan Qiang, Zheng Zhang, Xuping Feng, Lin Xu, Rui Xie, Hongyu Zhou, Jiwei Huang, Yong Zeng, Haichuan Wang
Journal: Cancer Research
Cancer Res (2025) 85 (6): 1035–1048.
https://doi.org/10.1158/0008-5472.CAN-24-0147
Published: 14 March 2025
View articletitled, CLK1 Activates YAP to Promote Intrahepatic Cholangiocarcinogenesis
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Includes: Supplementary data
Journal Articles

The circRNA cEMSY Induces Immunogenic Cell Death and Boosts Immunotherapy Efficacy in Lung Adenocarcinoma

Open Access
Yijian Zhang, Xuming Song, Yipeng Feng, Yuxian Qian, Bing Chen, Te Zhang, Hui Wang, Yuzhong Chen, Xinnian Yu, Hanlin Ding, Rutao Li, Pengfei Ge, Lin Xu, Gaochao Dong, Feng Jiang
Journal: Cancer Research
Cancer Res (2025) 85 (3): 497–514.
https://doi.org/10.1158/0008-5472.CAN-24-1484
Published: 01 February 2025
View articletitled, The circRNA cEMSY Induces Immunogenic Cell Death and Boosts Immunotherapy Efficacy in Lung Adenocarcinoma
Open the PDF for The circRNA cEMSY Induces Immunogenic Cell Death and Boosts Immunotherapy Efficacy in Lung Adenocarcinoma in another window
Includes: Supplementary data
Journal Articles

Neuroendocrine Differentiation in Prostate Cancer Requires ASCL1

Available to Purchase
Kathia E. Rodarte, Shaked Nir Heyman, Lei Guo, Lydia Flores, Trisha K. Savage, Juan Villarreal, Su Deng, Lin Xu, Rajal B. Shah, Trudy G. Oliver, Jane E. Johnson
Journal: Cancer Research
Cancer Res (2024) 84 (21): 3522–3537.
https://doi.org/10.1158/0008-5472.CAN-24-1388
Published: 04 November 2024
View articletitled, Neuroendocrine Differentiation in Prostate Cancer Requires ASCL1
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Includes: Supplementary data
Journal Articles

Abstract PS03-04: Tumor immune microenvironment modulates resistance to estrogen suppression in ER+ breast cancer

Free
Fabiana Napolitano, Yunguan Wang, Dhivya Sudhan, Paula Gonzalez-Ericsson, Luigi Formisano, Lei Guo, M Rosario Chica-Parrado, Chang-Ching Lin, Kyung-Min Lee, Hongli Ma, Nathaniel Evans, Alberto Servetto, Saurabh Mendiratta, Spencer Barnes, Yisheng Fang, Lin Xu, Justin Balko, Gordon Mills, Marilyne Labrie, Ariella Hanker, Carlos Arteaga
Journal: Cancer Research
Cancer Res (2024) 84 (9_Supplement): PS03-04.
https://doi.org/10.1158/1538-7445.SABCS23-PS03-04
Published: 02 May 2024
View articletitled, Abstract PS03-04: Tumor immune microenvironment modulates resistance to estrogen suppression in ER+ breast cancer
Journal Articles

Abstract LB257: Possible involvement of PDL1 intrinsic signaling to acquired resistance to immunotherapy for renal cell carcinoma (RCC)

Free
Jin-Sung Chung, Lei Guo, Vinita Popat, Ponciano D. Cruz, Lin Xu, Hans Hammers, Kiyoshi Ariizumi
Journal: Cancer Research
Cancer Res (2024) 84 (7_Supplement): LB257.
https://doi.org/10.1158/1538-7445.AM2024-LB257
Published: 05 April 2024
View articletitled, Abstract LB257: Possible involvement of PDL1 intrinsic signaling to acquired resistance to immunotherapy for renal cell carcinoma (RCC)
Journal Articles

Abstract LB311: Multimodal spatial profiling reveals the emergence of an immune suppressive microenvironment at the initial stages of high-grade serous ovarian cancer development

Free
Tanjina Kader, Jia-Ren Lin, Shannon Coy, Clemens Hug, Yu-An Chen, Roxanne J. Pelletier, Mariana Leon, John Lee, Yi-Lin Xu, Clarence Yapp, Natalie Shih, Gabriel Mingo, Euihye Jung, Srishti Rathore, Judith Agudo, Charles Drescher, Peter K. Sorger, Ronny Drapkin, Sandro Santagata
Journal: Cancer Research
Cancer Res (2024) 84 (7_Supplement): LB311.
https://doi.org/10.1158/1538-7445.AM2024-LB311
Published: 05 April 2024
View articletitled, Abstract LB311: Multimodal spatial profiling reveals the emergence of an immune suppressive microenvironment at the initial stages of high-grade serous ovarian cancer development
Journal Articles

Abstract 5708: Silence exportin 7 sensitizes esophageal squamous cell cancer to CDK4/6 inhibition through block the cell cycle coresectory

Free
Zhong Wu, Lin Xu, Chuang Jiang, Adam Bass, Jin Zhou
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 5708.
https://doi.org/10.1158/1538-7445.AM2024-5708
Published: 22 March 2024
View articletitled, Abstract 5708: Silence exportin 7 sensitizes esophageal squamous cell cancer to CDK4/6 inhibition through block the cell cycle coresectory
Journal Articles

Abstract 131: Utilizing human induced pluripotent stem cells (hiPSCs) as a model to study the genetic drivers of rhabdomyosarcoma

Free
Celeste Romero, Yanbin Zheng, Lin Xu, Stephen Skapek
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 131.
https://doi.org/10.1158/1538-7445.AM2024-131
Published: 22 March 2024
View articletitled, Abstract 131: Utilizing human induced pluripotent stem cells (hiPSCs) as a model to study the genetic drivers of rhabdomyosarcoma
Journal Articles

Abstract 1097: CD73 contributes to the pathogenesis of fusion-negative rhabdomyosarcoma through the purinergic signaling pathway

Free
Karla Gabriela Cano Hernandez, Akansha Shah, Victor Lopez, Vincent Tagliabracci, Kenian Chen, Lin Xu, Rhonda Bassel-Duby, Eric Olson, Ning Liu
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 1097.
https://doi.org/10.1158/1538-7445.AM2024-1097
Published: 22 March 2024
View articletitled, Abstract 1097: CD73 contributes to the pathogenesis of fusion-negative rhabdomyosarcoma through the purinergic signaling pathway
Journal Articles

Abstract 4750: TWIST2 mediated chromatin remodeling promotes fusion-negative rhabdomyosarcoma

Free
Akansha M. Shah, Lei Guo, Maria Gabriella Morales, Priscilla Jaichander, Kenian Chen, Huocong Huang, Karla Cano Hernandez, Lin Xu, Rhonda Bassel-Duby, Eric N. Olson, Ning Liu
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 4750.
https://doi.org/10.1158/1538-7445.AM2023-4750
Published: 04 April 2023
View articletitled, Abstract 4750: TWIST2 mediated chromatin remodeling promotes fusion-negative rhabdomyosarcoma
Journal Articles

Abstract 3572: Genomic profiling of subcutaneous patient derived xenograft models of solid childhood cancer

Free
Funan He, Abhik M. Bandyopadhyay, Laura Klesse, Anna Rogojina, Erin Butler, Taylor Hartshorne, Trevor Holland, Luz Perez Prado, Anne-Marie Langevan, Allison C. Grimes, Chatchawin Assanasen, Zhao Lai, Yi Zou, Dias Kurmashev, Lin Xu, Yang Xie, Yidong Chen, Xiaojing Wang, Gail E. Tomlinson, Stephen X. Skapek, Raushan T. Kurmasheva, Peter J. Houghton, Siyuan Zheng
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 3572.
https://doi.org/10.1158/1538-7445.AM2023-3572
Published: 04 April 2023
View articletitled, Abstract 3572: Genomic profiling of subcutaneous patient derived xenograft models of solid childhood cancer
Journal Articles

Abstract 3525: VGLL2-NCOA2 leverages developmental programs for pediatric sarcomagenesis

Free
Sarah Watson, Collette A. LaVigne, Lin Xu, Didier Surdez, Joanna Cyrta, Delia Calderon, Matthew V. Cannon, Matthew R. Kent, Katherine M. Silvius, Jack P. Kucinski, Emma N. Harrison, Whitney Murchison, Dinesh Rakheja, Franck Tirode, Olivier Delattre, James F. Amatruda, Genevieve C. Kendall
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 3525.
https://doi.org/10.1158/1538-7445.AM2023-3525
Published: 04 April 2023
View articletitled, Abstract 3525: VGLL2-NCOA2 leverages developmental programs for pediatric sarcomagenesis
Journal Articles

Abstract 3934: PRMT5 is an actionable target in CDK4/6 inhibitor-resistant ER+/Rb-deficient breast cancer

Free
Chang-Ching Lin, Tsung-Cheng Chang, Yunguan Wang, Yanfeng Zhang, Andrew Lemoff, Yisheng V. Fang, He Zhang, Dan Ye, Isabel Soria-Bretones, Alberto Servetto, Kyung-min Lee, Xuemei Luo, Joseph J. Otto, Hiroaki Akamatsu, David W. Cescon, Lin Xu, Yang Xie, Joshua T. Mendell, Ariella B. Hanker, Carlos L. Arteaga
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 3934.
https://doi.org/10.1158/1538-7445.AM2023-3934
Published: 04 April 2023
View articletitled, Abstract 3934: PRMT5 is an actionable target in CDK4/6 inhibitor-resistant ER+/Rb-deficient breast cancer
Journal Articles

Abstract GS5-06: InteractPrint predicts clinically meaningful interactions between cancer epithelial cells and immune cells: Lessons from a single-cell breast cancer atlas

Free
Lily Xu, Kaitlyn Saunders, Hildur Knutsdottir, Kenian Chen, Julia Maues, Christine Hodgdon, Evanthia T. Roussos Torres, Sangeetha Reddy, Lin Xu, Isaac Chan
Journal: Cancer Research
Cancer Res (2023) 83 (5_Supplement): GS5-06.
https://doi.org/10.1158/1538-7445.SABCS22-GS5-06
Published: 01 March 2023
View articletitled, Abstract GS5-06: InteractPrint predicts clinically meaningful interactions between cancer epithelial cells and immune cells: Lessons from a single-cell breast cancer atlas
Journal Articles

Abstract 6193: TWIST2 promotes tumor progression and represses myogenic differentiation in rhabdomyosarcoma

Free
Akansha Shah, Lei Guo, Priscilla Jaichander, Kenian Chen, Karla Cano Hernandez, Lin Xu, Rhonda Bassel-Duby, Eric Olson, Ning Liu
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 6193.
https://doi.org/10.1158/1538-7445.AM2022-6193
Published: 15 June 2022
View articletitled, Abstract 6193: TWIST2 promotes tumor progression and represses myogenic differentiation in rhabdomyosarcoma
Journal Articles

Genetic Risk for Overall Cancer and the Benefit of Adherence to a Healthy Lifestyle

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Meng Zhu, Tianpei Wang, Yanqian Huang, Xiaoyu Zhao, Yuqing Ding, Mengyi Zhu, Mengmeng Ji, Cheng Wang, Juncheng Dai, Rong Yin, Lin Xu, Hongxia Ma, Qingyi Wei, Guangfu Jin, Zhibin Hu, Hongbing Shen
Journal: Cancer Research
Cancer Res (2021) 81 (17): 4618–4627.
https://doi.org/10.1158/0008-5472.CAN-21-0836
Published: 01 September 2021
View articletitled, Genetic Risk for Overall Cancer and the Benefit of Adherence to a Healthy Lifestyle
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Includes: Supplementary data
Journal Articles

Abstract 2832: Targeted genomic landscape of metastases compared to primary tumors in non-small-cell lung cancer

Free
Bing Chen, Gaochao Dong, Yingkuan Liang, Te Zhang, Junling Zhang, Shiqing Chen, Feng Jiang, Lin Xu
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2832.
https://doi.org/10.1158/1538-7445.AM2021-2832
Published: 01 July 2021
View articletitled, Abstract 2832: Targeted genomic landscape of metastases compared to primary tumors in non-small-cell lung cancer
Journal Articles

Computational Staining of Pathology Images to Study the Tumor Microenvironment in Lung Cancer

Available to Purchase
Shidan Wang, Ruichen Rong, Donghan M. Yang, Junya Fujimoto, Shirley Yan, Ling Cai, Lin Yang, Danni Luo, Carmen Behrens, Edwin R. Parra, Bo Yao, Lin Xu, Tao Wang, Xiaowei Zhan, Ignacio I. Wistuba, John Minna, Yang Xie, Guanghua Xiao
Journal: Cancer Research
Cancer Res (2020) 80 (10): 2056–2066.
https://doi.org/10.1158/0008-5472.CAN-19-1629
Published: 15 May 2020
View articletitled, Computational Staining of Pathology Images to Study the Tumor Microenvironment in Lung Cancer
Open the PDF for Computational Staining of Pathology Images to Study the Tumor Microenvironment in Lung Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract 872: Genetic models reveal that the novel VGLL2-NCOA2 fusion oncogene leverages embryonic programs for sarcomagenesis

Free
Genevieve C. Kendall, Sarah Watson, Lin Xu, Collette LaVigne, Whitney Murchison, Dinesh Rakheja, Franck Tirode, Olivier Delattre, James Amatruda
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 872.
https://doi.org/10.1158/1538-7445.AM2019-872
Published: 01 July 2019
View articletitled, Abstract 872: Genetic models reveal that the novel VGLL2-NCOA2 fusion oncogene leverages embryonic programs for sarcomagenesis