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Journal Articles

Faecalibacterium prausnitzii Abrogates Intestinal Toxicity and Promotes Tumor Immunity to Increase the Efficacy of Dual CTLA4 and PD-1 Checkpoint Blockade

Yaqi Gao, Pingping Xu, Danfeng Sun, Yi Jiang, Xiao-Lin Lin, Ting Han, Jun Yu, Chunquan Sheng, Haoyan Chen, Jie Hong, Yingxuan Chen, Xiu-Ying Xiao, Jing-Yuan Fang

Cancer Res (2023) 83 (22): 3710–3725.

https://doi.org/10.1158/0008-5472.CAN-23-0605

Published: 15 November 2023

View article titled, <em>Faecalibacterium prausnitzii</em> Abrogates Intestinal Toxicity and Promotes Tumor Immunity to Increase the Efficacy of Dual CTLA4 and PD-1 Checkpoint Blockade

Includes: Supplementary data

Journal Articles

Abstract 112: Multi-omics analysis of molecular landscape and heterogeneity in fetal adenocarcinoma of the lung

Wei Guo, Li Sun, Xiaoxi Chen, Haitao Zhou, Shi Yan, Gang Zhao, Haimeng Tang, Hua Bao, Xue Wu, Yang Shao, Lin Lin

Cancer Res (2023) 83 (7_Supplement): 112.

https://doi.org/10.1158/1538-7445.AM2023-112

Published: 04 April 2023

View article titled, Abstract 112: Multi-omics analysis of molecular landscape and heterogeneity in fetal adenocarcinoma of the lung

Journal Articles

Abstract 3870: TNF-MK2 signaling drives protective autophagy following MAPK pathway inhibition in pancreatic cancer

Iftikhar Ali Khawar, Qing Wei, Timothy Hung-Po Chen, Lin Lin, Patrick M. Grierson, Kian-Huat Lim

Cancer Res (2023) 83 (7_Supplement): 3870.

https://doi.org/10.1158/1538-7445.AM2023-3870

Published: 04 April 2023

View article titled, Abstract 3870: TNF-MK2 signaling drives protective autophagy following MAPK pathway inhibition in pancreatic cancer

Journal Articles

Computational Identification of Preneoplastic Cells Displaying High Stemness and Risk of Cancer Progression

Tianyuan Liu, Xuan Zhao, Yuan Lin, Qi Luo, Shaosen Zhang, Yiyi Xi, Yamei Chen, Lin Lin, Wenyi Fan, Jie Yang, Yuling Ma, Alok K. Maity, Yanyi Huang, Jianbin Wang, Jiang Chang, Dongxin Lin, Andrew E. Teschendorff, Chen Wu

Cancer Res (2022) 82 (14): 2520–2537.

https://doi.org/10.1158/0008-5472.CAN-22-0668

Published: 18 July 2022

View article titled, Computational Identification of Preneoplastic Cells Displaying High Stemness and Risk of Cancer Progression

Includes: Supplementary data

Journal Articles

Abstract PO-028: Pancreatic ductal adenocarcinoma is dependent on an unconventional pathway for polyamine synthesis

Min-Sik Lee, Insia Naqvi, Courtney Dennis, Lucas Dailey, Alireza Lorzadeh, Tamara Zaytouni, Ashley Adler, Daniel S. Hitchcock, Lin Lin, Unmesh Jadhav, Clary B. Clish, Nada Y. Kalaany

Cancer Res (2021) 81 (22_Supplement): PO-028.

https://doi.org/10.1158/1538-7445.PANCA21-PO-028

Published: 15 November 2021

View article titled, Abstract PO-028: Pancreatic ductal adenocarcinoma is dependent on an unconventional pathway for polyamine synthesis

Journal Articles

Contacts with Macrophages Promote an Aggressive Nanomechanical Phenotype of Circulating Tumor Cells in Prostate Cancer

Pawel A. Osmulski, Alessandra Cunsolo, Meizhen Chen, Yusheng Qian, Chun-Lin Lin, Chia-Nung Hung, Devalingam Mahalingam, Nameer B. Kirma, Chun-Liang Chen, Josephine A. Taverna, Michael A. Liss, Ian M. Thompson, Tim H.-M. Huang, Maria E. Gaczynska

Cancer Res (2021) 81 (15): 4110–4123.

https://doi.org/10.1158/0008-5472.CAN-20-3595

Published: 01 August 2021

View article titled, Contacts with Macrophages Promote an Aggressive Nanomechanical Phenotype of Circulating Tumor Cells in Prostate Cancer

Includes: Supplementary data

Journal Articles

Single-Cell Proteomic Profiling Identifies Combined AXL and JAK1 Inhibition as a Novel Therapeutic Strategy for Lung Cancer

Cancer Res (2020) 80 (7): 1551–1563.

https://doi.org/10.1158/0008-5472.CAN-19-3183

Published: 02 April 2020

View article titled, Single-Cell Proteomic Profiling Identifies Combined AXL and JAK1 Inhibition as a Novel Therapeutic Strategy for Lung Cancer

Includes: Supplementary data

Journal Articles

Abstract P4-05-17: ESR1 related chromothripsis enhances concordant gene transcription on chromosome 17q11.1-q24.1 in luminal breast cancer

Chun-Lin Lin

Cancer Res (2020) 80 (4_Supplement): P4-05-17.

https://doi.org/10.1158/1538-7445.SABCS19-P4-05-17

Published: 15 February 2020

View article titled, Abstract P4-05-17: ESR1 related chromothripsis enhances concordant gene transcription on chromosome 17q11.1-q24.1 in luminal breast cancer

Journal Articles

Abstract 2766: Amplification-associated upregulation of genes involved in oxidative phosphorylation for disseminated prostate cancer cells

Chun-Lin Lin, Tan Xi, Chia-Nung Hung, Pawel A. Osmulski, Chih-Wei Chou, Meizhen Chen, Chiou-Miin Wang, Kohzoh Mitsuya, Nameer Kirma, Maria E. Gaczynska, Chun-Liang Chen, Tim H.-M. Huang

Cancer Res (2019) 79 (13_Supplement): 2766.

https://doi.org/10.1158/1538-7445.AM2019-2766

Published: 01 July 2019

View article titled, Abstract 2766: Amplification-associated upregulation of genes involved in oxidative phosphorylation for disseminated prostate cancer cells

Journal Articles

Abstract 3943: Inhibition of ribosomal protein RPS6KB1 as a strategy to improve conventional therapy for prostate cancer

Alison D. Clark, Suleman S. Hussain, Shih-Bo Huang, Roble G. Bedolla, Mohammad A. Obeidat, Niko Papanikolaou, Chun Lin Lin, Tim H. Huang, Yogesh Gupta, Yidong Chen, Hiroshi Miyamoto, Rita Ghosh, Addanki P. Kumar

Cancer Res (2019) 79 (13_Supplement): 3943.

https://doi.org/10.1158/1538-7445.AM2019-3943

Published: 01 July 2019

View article titled, Abstract 3943: Inhibition of ribosomal protein RPS6KB1 as a strategy to improve conventional therapy for prostate cancer

Journal Articles

Abstract 4126: Inferring target occupancy from fitting nonlinear-PK data with mechanistic PKRO model for Pembrolizumab

Fei Hua, Lin Lin, Lore Gruenbaum, Bjorn L. Millard, John M. Burke, Joshua F. Apgar

Cancer Res (2019) 79 (13_Supplement): 4126.

https://doi.org/10.1158/1538-7445.AM2019-4126

Published: 01 July 2019

View article titled, Abstract 4126: Inferring target occupancy from fitting nonlinear-PK data with mechanistic PKRO model for Pembrolizumab

Journal Articles

Abstract 2193: AXL inhibitor TP-0903 attenuates AXL-TGFbeta Hippo signaling axis in lung adenocarcinoma cells

Josephine Amalia Taverna, Chia-Nung Hung, Chun-Lin Lin, Pawel Osmulski, Meizhen Chen, Chiou-Miin Wang, Nicholas L. L. Lucio, Nameer Kirma, Chih-Wei Chou, Maria E. Gaczynska, Alia Nazarullah, Mark Wade, Lars Mouritsen, Tim Huang

Cancer Res (2019) 79 (13_Supplement): 2193.

https://doi.org/10.1158/1538-7445.AM2019-2193

Published: 01 July 2019

View article titled, Abstract 2193: AXL inhibitor TP-0903 attenuates AXL-TGFbeta Hippo signaling axis in lung adenocarcinoma cells

Journal Articles

Abstract 685: Development of a multiscale QSP model to characterize the tumor suppressive effects of a cytokine mRNA immunotherapy in a preclinical melanoma mouse model

Kamau Pierre, Lin Lin, Lore Gruenbaum, Carissa Young, Joshua Apgar, Christian Hotz, Timothy Wagenaar, Spyros K. Stamatelos

Cancer Res (2019) 79 (13_Supplement): 685.

https://doi.org/10.1158/1538-7445.AM2019-685

Published: 01 July 2019

View article titled, Abstract 685: Development of a multiscale QSP model to characterize the tumor suppressive effects of a cytokine mRNA immunotherapy in a preclinical melanoma mouse model

Journal Articles

Abstract 684: A semi-mechanistic platform model to capture individual animal responses to checkpoint inhibitors in a syngeneic mouse model

Alison M. Betts, Lin Lin, Carissa L. Young, Wenlian Qiao, Jatin Narula, Peter O'Brien, Derek Bartlett, Andrea Hooper, Jason Williams, John M. Burke, Joshua Apgar, Fei Hua, Lore Gruenbaum

Cancer Res (2019) 79 (13_Supplement): 684.

https://doi.org/10.1158/1538-7445.AM2019-684

Published: 01 July 2019

View article titled, Abstract 684: A semi-mechanistic platform model to capture individual animal responses to checkpoint inhibitors in a syngeneic mouse model

Journal Articles

Abstract 5150: Adipose-derived stem cell disruption of gap junction intercellular communication in obesity-associated endometrial cancer

Li-Ling Lin, Srikanth Polusani, Guangcun Huang, Chun-Lin Lin, Chiou-Miin Wang, Nicholas Lucio, Mikhail Kolonin, Alexes Daquinag, Pawel Osmulski, Bruce Nicholson, Edward Kost, Tim Huang, Nameer B. Kirma

Cancer Res (2019) 79 (13_Supplement): 5150.

https://doi.org/10.1158/1538-7445.AM2019-5150

Published: 01 July 2019

View article titled, Abstract 5150: Adipose-derived stem cell disruption of gap junction intercellular communication in obesity-associated endometrial cancer

Journal Articles

Abstract 173: Upregulated EPHB2 and SRC pathways modulate spatial EGFR dynamics and malignant phenotypes and predict poor prognosis in prostate cancer

Yen-Liang Liu, Aaron M. Horning, Che-Kuang Lin, Brandon Lieberman, Chia-Nung Hung, Chih-Wei Chou, Chiou-Miin Wang, Michael A. Liss, Mirae Kim, Rohan Vasisht, Evan P. Perillo, Katherine Blocher, Hannah Horng, Xi Tian, Chun-Lin Lin, Andrew K. Dunn, Tim H.-M. Huang, Hsin-Chih Yeh, Chun-Liang Chen

Cancer Res (2019) 79 (13_Supplement): 173.

https://doi.org/10.1158/1538-7445.AM2019-173

Published: 01 July 2019

View article titled, Abstract 173: Upregulated EPHB2 and SRC pathways modulate spatial EGFR dynamics and malignant phenotypes and predict poor prognosis in prostate cancer

Journal Articles

Abstract SY43-03: Long-range epigenetic control of estrogen-responsive transcription

Chun-Lin Lin, Tim Hui-Ming Huang

Cancer Res (2019) 79 (13_Supplement): SY43-03.

https://doi.org/10.1158/1538-7445.AM2019-SY43-03

Published: 01 July 2019

View article titled, Abstract SY43-03: Long-range epigenetic control of estrogen-responsive transcription

Journal Articles

Adipokines Deregulate Cellular Communication via Epigenetic Repression of Gap Junction Loci in Obese Endometrial Cancer

Cancer Res (2019) 79 (1): 196–208.

https://doi.org/10.1158/0008-5472.CAN-18-1615

Published: 02 January 2019

View article titled, Adipokines Deregulate Cellular Communication via Epigenetic Repression of <em>Gap Junction</em> Loci in Obese Endometrial Cancer

Includes: Supplementary data

Journal Articles

miR-508 Defines the Stem-like/Mesenchymal Subtype in Colorectal Cancer

Cancer Res (2018) 78 (7): 1751–1765.

https://doi.org/10.1158/0008-5472.CAN-17-2101

Published: 01 April 2018

View article titled, miR-508 Defines the Stem-like/Mesenchymal Subtype in Colorectal Cancer

Includes: Supplementary data

Journal Articles

Single-Cell RNA-seq Reveals a Subpopulation of Prostate Cancer Cells with Enhanced Cell-Cycle–Related Transcription and Attenuated Androgen Response

Aaron M. Horning, Yao Wang, Che-Kuang Lin, Anna D. Louie, Rohit R. Jadhav, Chia-Nung Hung, Chiou-Miin Wang, Chun-Lin Lin, Nameer B. Kirma, Michael A. Liss, Addanki P. Kumar, LuZhe Sun, Zhijie Liu, Wei-Ting Chao, Qianben Wang, Victor X. Jin, Chun-Liang Chen, Tim H.-M. Huang

Cancer Res (2018) 78 (4): 853–864.

https://doi.org/10.1158/0008-5472.CAN-17-1924

Published: 14 February 2018

View article titled, Single-Cell RNA-seq Reveals a Subpopulation of Prostate Cancer Cells with Enhanced Cell-Cycle–Related Transcription and Attenuated Androgen Response

Includes: Supplementary data

NARROW

Faecalibacterium prausnitzii Abrogates Intestinal Toxicity and Promotes Tumor Immunity to Increase the Efficacy of Dual CTLA4 and PD-1 Checkpoint Blockade

Abstract 112: Multi-omics analysis of molecular landscape and heterogeneity in fetal adenocarcinoma of the lung

Abstract 3870: TNF-MK2 signaling drives protective autophagy following MAPK pathway inhibition in pancreatic cancer

Computational Identification of Preneoplastic Cells Displaying High Stemness and Risk of Cancer Progression

Abstract PO-028: Pancreatic ductal adenocarcinoma is dependent on an unconventional pathway for polyamine synthesis

Contacts with Macrophages Promote an Aggressive Nanomechanical Phenotype of Circulating Tumor Cells in Prostate Cancer

Single-Cell Proteomic Profiling Identifies Combined AXL and JAK1 Inhibition as a Novel Therapeutic Strategy for Lung Cancer

Abstract P4-05-17: ESR1 related chromothripsis enhances concordant gene transcription on chromosome 17q11.1-q24.1 in luminal breast cancer

Abstract 2766: Amplification-associated upregulation of genes involved in oxidative phosphorylation for disseminated prostate cancer cells

Abstract 3943: Inhibition of ribosomal protein RPS6KB1 as a strategy to improve conventional therapy for prostate cancer

Abstract 4126: Inferring target occupancy from fitting nonlinear-PK data with mechanistic PKRO model for Pembrolizumab

Abstract 2193: AXL inhibitor TP-0903 attenuates AXL-TGFbeta Hippo signaling axis in lung adenocarcinoma cells

Abstract 685: Development of a multiscale QSP model to characterize the tumor suppressive effects of a cytokine mRNA immunotherapy in a preclinical melanoma mouse model

Abstract 684: A semi-mechanistic platform model to capture individual animal responses to checkpoint inhibitors in a syngeneic mouse model

Abstract 5150: Adipose-derived stem cell disruption of gap junction intercellular communication in obesity-associated endometrial cancer

Abstract 173: Upregulated EPHB2 and SRC pathways modulate spatial EGFR dynamics and malignant phenotypes and predict poor prognosis in prostate cancer

Abstract SY43-03: Long-range epigenetic control of estrogen-responsive transcription

Adipokines Deregulate Cellular Communication via Epigenetic Repression of Gap Junction Loci in Obese Endometrial Cancer

miR-508 Defines the Stem-like/Mesenchymal Subtype in Colorectal Cancer

Single-Cell RNA-seq Reveals a Subpopulation of Prostate Cancer Cells with Enhanced Cell-Cycle–Related Transcription and Attenuated Androgen Response

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