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Journal Articles

Thymosin α-1 Reverses M2 Polarization of Tumor-Associated Macrophages during Efferocytosis

Yi-ting Wei, Xu-ru Wang, Chunguang Yan, Fang Huang, Yunpeng Zhang, Xueming Liu, Zhi-fa Wen, Xiao-tong Sun, Yue Zhang, Yong-qiang Chen, Rong Gao, Ning Pan, Li-xin Wang

Cancer Res (2022) 82 (10): 1991–2002.

DOI: https://doi.org/10.1158/0008-5472.CAN-21-4260

Published: 16 May 2022

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Includes: Supplementary data

Journal Articles

Abstract 2478: A mAb with in vivo therapeutic activity against spontaneous breast tumors in FVB-neuN mice recognizes SLP-2

Li-Xin Wang, Michael Berk, Gregory E. Plautz

Cancer Res (2015) 75 (15_Supplement): 2478.

DOI: https://doi.org/10.1158/1538-7445.AM2015-2478

Published: 01 August 2015

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Journal Articles

Abstract A85: Passenger genes on tumor-associated amplicons function as tumor rejection antigens

Michael Berk, Arun Modi, Mona Patel, Li-Xin Wang, Gregory Plautz

Cancer Res (2014) 74 (20_Supplement): A85.

DOI: https://doi.org/10.1158/1538-7445.PEDCAN-A85

Published: 09 October 2014

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Journal Articles

Abstract 2897: ERBB2 amplicon passenger genes: A novel class of breast cancer antigens

Gregory E. Plautz, Arun Modi, Li-Xin Wang

Cancer Res (2014) 74 (19_Supplement): 2897.

DOI: https://doi.org/10.1158/1538-7445.AM2014-2897

Published: 01 October 2014

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Journal Articles

Abstract 2551: B cells induced during CD4⁺ T-cell mediated destruction of primary tumors in neuN mice produce mAbs that are capable of inhibiting spontaneous tumor growth

Li-Xin Wang, Mona Patel, Michael Berk, Gregory Plautz

Cancer Res (2014) 74 (19_Supplement): 2551.

DOI: https://doi.org/10.1158/1538-7445.AM2014-2551

Published: 01 October 2014

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Journal Articles

Abstract 2853: Monoclonal antibodies derived in neuN mice following successful T cell therapy of spontaneous breast tumors are specific for tumor progenitor cells.

Li-Xin Wang, Mona Patel, Michael Berk, Gregory E. Plautz

Cancer Res (2013) 73 (8_Supplement): 2853.

DOI: https://doi.org/10.1158/1538-7445.AM2013-2853

Published: 15 April 2013

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Journal Articles

Abstract 771: Therapy of spontaneous primary breast tumors in neu-N transgenic mice by adoptive transfer of vaccine-primed LN T cells also induces a humoral response

Li-Xin Wang, Gregory E. Plautz

Cancer Res (2011) 71 (8_Supplement): 771.

DOI: https://doi.org/10.1158/1538-7445.AM2011-771

Published: 15 April 2011

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Journal Articles

Abstract 1929: CD4⁺ and CD8⁺ neu-reactive T cells are sensitized by breast cancer stem-like cells (BCSC) in tolerized Her-2/neu transgenic mice and can mediate tumor regression upon adoptive transfer

Li-Xin Wang, Gary K. Koski, Gregory E. Plautz

Cancer Res (2010) 70 (8_Supplement): 1929.

DOI: https://doi.org/10.1158/1538-7445.AM10-1929

Published: 15 April 2010

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Journal Articles

Abstract #2414: Tumor antigen-specific CD62L^lowCD4+ T cells adoptively transferred to normal hosts develop effector and central memory phenotypes and retain therapeutic function

Li-Xin Wang, Gregory Plautz

Cancer Res (2009) 69 (9_Supplement): 2414.

Published: 01 May 2009

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Journal Articles

Efficient Cross-presentation Depends on Autophagy in Tumor Cells

Yuhuan Li, Li-Xin Wang, Guojun Yang, Fang Hao, Walter J. Urba, Hong-Ming Hu

Cancer Res (2008) 68 (17): 6889–6895.

DOI: https://doi.org/10.1158/0008-5472.CAN-08-0161

Published: 28 August 2008

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Includes: Supplementary data

Journal Articles

Tumor-infiltrating lymphocytes (TIL) contain a subset of suppressor CD8⁺ T cells which can inhibit primary sensitization of tumor-specific effector T cells

Li-Xin Wang, Suyu Shu, Gregory Plautz

Cancer Res (2008) 68 (9_Supplement): 4634.

Published: 01 May 2008

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Journal Articles

Tumor-induced CD11b⁺Gr-1⁺ myeloid cells promote tumor growth and regulate T cell sensitization in the draining lymph node

Satoshi Watanabe, Rongxiu Zheng, Katsuya Deguchi, Li-Xin Wang, Peter Cohen, Suyu Shu

Cancer Res (2007) 67 (9_Supplement): 218.

Published: 01 May 2007

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Journal Articles

Tumor-infiltrating lymphocytes (TIL) contain effector and regulatory subsets that can be effectively segregated and hyperexpanded in vitro with maintenance of distinct functional properties.

Li-Xin Wang, Suyu Shu, Gregory Plautz

Cancer Res (2007) 67 (9_Supplement): 964.

Published: 01 May 2007

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Journal Articles

CD4 tumor-reactive T cells enhance intratumoral proliferation and effector function of CD8 cells and synergistically mediate tumor regression.

Li-Xin Wang, Suyu Shu, Gregory E. Plautz

Cancer Res (2006) 66 (8_Supplement): 1308–1309.

Published: 15 April 2006

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Journal Articles

Interleukin-7-Dependent Expansion and Persistence of Melanoma-Specific T Cells in Lymphodepleted Mice Lead to Tumor Regression and Editing

Li-Xin Wang, Rui Li, Guojun Yang, May Lim, Aisling O'Hara, Yiwei Chu, Bernard A. Fox, Nicholas P. Restifo, Walter J. Urba, Hong-Ming Hu

Cancer Res (2005) 65 (22): 10569–10577.

DOI: https://doi.org/10.1158/0008-5472.CAN-05-2117

Published: 15 November 2005

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Journal Articles

Host Lymphodepletion Augments T Cell Adoptive Immunotherapy through Enhanced Intratumoral Proliferation of Effector Cells

Li-Xin Wang, Suyu Shu, Gregory E. Plautz

Cancer Res (2005) 65 (20): 9547–9554.

DOI: https://doi.org/10.1158/0008-5472.CAN-05-1175

Published: 17 October 2005

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Journal Articles

Active immunotherapy of advanced intracranial tumors through intrasplenic vaccination with DC-tumor electrofusion heterokaryons

Jorgen Kjaergaard, Gregory Plautz, Li-Xin Wang, Hideyuki Kuriyama, Keiji Shimizu, David Weng, Suyu Shu

Cancer Res (2004) 64 (7_Supplement): 294.

Published: 01 April 2004

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Journal Articles

Adoptive immunotherapy with polyclonal tumor-reactive CD8 T cells hyperexpanded to greater than 10⁸-fold.

Gregory E. Plautz, Li-Xin Wang, Suyu Shu

Cancer Res (2004) 64 (7_Supplement): 501.

Published: 01 April 2004

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NARROW

Thymosin α-1 Reverses M2 Polarization of Tumor-Associated Macrophages during Efferocytosis

Abstract 2478: A mAb with in vivo therapeutic activity against spontaneous breast tumors in FVB-neuN mice recognizes SLP-2

Abstract A85: Passenger genes on tumor-associated amplicons function as tumor rejection antigens

Abstract 2897: ERBB2 amplicon passenger genes: A novel class of breast cancer antigens

Abstract 2551: B cells induced during CD4⁺ T-cell mediated destruction of primary tumors in neuN mice produce mAbs that are capable of inhibiting spontaneous tumor growth

Abstract 2853: Monoclonal antibodies derived in neuN mice following successful T cell therapy of spontaneous breast tumors are specific for tumor progenitor cells.

Abstract 771: Therapy of spontaneous primary breast tumors in neu-N transgenic mice by adoptive transfer of vaccine-primed LN T cells also induces a humoral response

Abstract 1929: CD4⁺ and CD8⁺ neu-reactive T cells are sensitized by breast cancer stem-like cells (BCSC) in tolerized Her-2/neu transgenic mice and can mediate tumor regression upon adoptive transfer

Abstract #2414: Tumor antigen-specific CD62L^lowCD4+ T cells adoptively transferred to normal hosts develop effector and central memory phenotypes and retain therapeutic function

Efficient Cross-presentation Depends on Autophagy in Tumor Cells

Tumor-infiltrating lymphocytes (TIL) contain a subset of suppressor CD8⁺ T cells which can inhibit primary sensitization of tumor-specific effector T cells

Tumor-induced CD11b⁺Gr-1⁺ myeloid cells promote tumor growth and regulate T cell sensitization in the draining lymph node

Tumor-infiltrating lymphocytes (TIL) contain effector and regulatory subsets that can be effectively segregated and hyperexpanded in vitro with maintenance of distinct functional properties.

CD4 tumor-reactive T cells enhance intratumoral proliferation and effector function of CD8 cells and synergistically mediate tumor regression.

Interleukin-7-Dependent Expansion and Persistence of Melanoma-Specific T Cells in Lymphodepleted Mice Lead to Tumor Regression and Editing

Host Lymphodepletion Augments T Cell Adoptive Immunotherapy through Enhanced Intratumoral Proliferation of Effector Cells

Active immunotherapy of advanced intracranial tumors through intrasplenic vaccination with DC-tumor electrofusion heterokaryons

Adoptive immunotherapy with polyclonal tumor-reactive CD8 T cells hyperexpanded to greater than 10⁸-fold.

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