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Journal Articles

Multiomic Analysis of Subtype Evolution and Heterogeneity in High-Grade Serous Ovarian Carcinoma

Ludwig Geistlinger, Sehyun Oh, Marcel Ramos, Lucas Schiffer, Rebecca S. LaRue, Christine M. Henzler, Sarah A. Munro, Claire Daughters, Andrew C. Nelson, Boris J. Winterhoff, Zenas Chang, Shobhana Talukdar, Mihir Shetty, Sally A. Mullany, Martin Morgan, Giovanni Parmigiani, Michael J. Birrer, Li-Xuan Qin, Markus Riester, Timothy K. Starr, Levi Waldron
Journal: Cancer Research
Cancer Res (2020) 80 (20): 4335–4345.
https://doi.org/10.1158/0008-5472.CAN-20-0521
Published: 15 October 2020
View article titled, Multiomic Analysis of Subtype Evolution and Heterogeneity in High-Grade Serous Ovarian Carcinoma
Open the PDF for Multiomic Analysis of Subtype Evolution and Heterogeneity in High-Grade Serous Ovarian Carcinoma in another window
Includes: Supplementary data
Journal Articles

Rb and p53-Deficient Myxofibrosarcoma and Undifferentiated Pleomorphic Sarcoma Require Skp2 for Survival

George Z. Li, Tomoyo Okada, Young-Mi Kim, Narasimhan P. Agaram, Francisco Sanchez-Vega, Yawei Shen, Norifumi Tsubokawa, Jordan Rios, Axel S. Martin, Mark A. Dickson, Li-Xuan Qin, Nicholas D. Socci, Samuel Singer
Journal: Cancer Research
Cancer Res (2020) 80 (12): 2461–2471.
https://doi.org/10.1158/0008-5472.CAN-19-1269
Published: 15 June 2020
View article titled, Rb and p53-Deficient Myxofibrosarcoma and Undifferentiated Pleomorphic Sarcoma Require Skp2 for Survival
Open the PDF for Rb and p53-Deficient Myxofibrosarcoma and Undifferentiated Pleomorphic Sarcoma Require Skp2 for Survival in another window
Includes: Supplementary data
Journal Articles

miR-193b–Regulated Signaling Networks Serve as Tumor Suppressors in Liposarcoma and Promote Adipogenesis in Adipose-Derived Stem Cells

Ying Z. Mazzu, Yulan Hu, Rajesh K. Soni, Kelly M. Mojica, Li-Xuan Qin, Phaedra Agius, Zachary M. Waxman, Aleksandra Mihailovic, Nicholas D. Socci, Ronald C. Hendrickson, Thomas Tuschl, Samuel Singer
Journal: Cancer Research
Cancer Res (2017) 77 (21): 5728–5740.
https://doi.org/10.1158/0008-5472.CAN-16-2253
Published: 31 October 2017
View article titled, miR-193b–Regulated Signaling Networks Serve as Tumor Suppressors in Liposarcoma and Promote Adipogenesis in Adipose-Derived Stem Cells
Open the PDF for miR-193b–Regulated Signaling Networks Serve as Tumor Suppressors in Liposarcoma and Promote Adipogenesis in Adipose-Derived Stem Cells in another window
Includes: Supplementary data
Journal Articles

Abstract A35: A recurrent neomorphic mutation in MYOD1 defines a clinically aggressive subset of embryonal rhabdomyosarcoma

Neerav Shukla, Shinji Kohsaka, Nabahet Ameur, Angela Yannes, Agnes Viale, Li-Xuan Qin, Snjezana Dogan, Raf Sciot, Julia Bridge, Paul Meyers, Leonard Wexler, Jonathan Fletcher, Marc Ladanyi
Journal: Cancer Research
Cancer Res (2014) 74 (20_Supplement): A35.
https://doi.org/10.1158/1538-7445.PEDCAN-A35
Published: 09 October 2014
View article titled, Abstract A35: A recurrent neomorphic mutation in MYOD1 defines a clinically aggressive subset of embryonal rhabdomyosarcoma
Journal Articles

Abstract 5061: Genomic and functional analysis of Myxofibrosarcoma identifies novel prognostic markers and promising therapeutic targets

Ann Y. Lee, Aimee M. Crago, Narasimhan P. Agaram, Tomoyo Okada, Penelope DeCarolis, Rachael B. O'Connor, Li-Xuan Qin, Raya Khanin, Yevgeniy Antipin, Boris A. Reva, Nicholas D. Socci, Samuel Singer
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 5061.
https://doi.org/10.1158/1538-7445.AM2012-5061
Published: 15 April 2012
View article titled, Abstract 5061: Genomic and functional analysis of Myxofibrosarcoma identifies novel prognostic markers and promising therapeutic targets
Journal Articles

Expression Profiling of Liposarcoma Yields a Multigene Predictor of Patient Outcome and Identifies Genes That Contribute to Liposarcomagenesis

Ryan M. Gobble, Li-Xuan Qin, Elliott R. Brill, Christina V. Angeles, Stacy Ugras, Rachael B. O'Connor, Nicole H. Moraco, Penelope L. DeCarolis, Cristina Antonescu, Samuel Singer
Journal: Cancer Research
Cancer Res (2011) 71 (7): 2697–2705.
https://doi.org/10.1158/0008-5472.CAN-10-3588
Published: 31 March 2011
View article titled, Expression Profiling of Liposarcoma Yields a Multigene Predictor of Patient Outcome and Identifies Genes That Contribute to Liposarcomagenesis
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Includes: Supplementary data
Journal Articles

Abstract 785: Gene expression profiling identifies two stable clusters of lobular carcinoma in situ

Victor P. Andrade, Mary Morrogh, Giri Dilip, Li-Xuan Qin, Rita Sakr, Narciso Olvera, Wooyul Paik, Muhsen Shirin, Edi Brodi, Monica Morrow, Tari A. King
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 785.
https://doi.org/10.1158/1538-7445.AM10-785
Published: 15 April 2010
View article titled, Abstract 785: Gene expression profiling identifies two stable clusters of lobular carcinoma in situ
Journal Articles

KDR Activating Mutations in Human Angiosarcomas Are Sensitive to Specific Kinase Inhibitors

Cristina R. Antonescu, Akihiko Yoshida, Tianhuo Guo, Ning-En Chang, Lei Zhang, Narasimhan P. Agaram, Li-Xuan Qin, Murray F. Brennan, Samuel Singer, Robert G. Maki
Journal: Cancer Research
Cancer Res (2009) 69 (18): 7175–7179.
https://doi.org/10.1158/0008-5472.CAN-09-2068
Published: 14 September 2009
View article titled, <em>KDR</em> Activating Mutations in Human Angiosarcomas Are Sensitive to Specific Kinase Inhibitors
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Journal Articles

γ-Secretase Inhibitors Abrogate Oxaliplatin-Induced Activation of the Notch-1 Signaling Pathway in Colon Cancer Cells Resulting in Enhanced Chemosensitivity

Raymond D. Meng, Christopher C. Shelton, Yue-Ming Li, Li-Xuan Qin, Daniel Notterman, Philip B. Paty, Gary K. Schwartz
Journal: Cancer Research
Cancer Res (2009) 69 (2): 573–582.
https://doi.org/10.1158/0008-5472.CAN-08-2088
Published: 15 January 2009
View article titled, γ-Secretase Inhibitors Abrogate Oxaliplatin-Induced Activation of the Notch-1 Signaling Pathway in Colon Cancer Cells Resulting in Enhanced Chemosensitivity
Open the PDF for γ-Secretase Inhibitors Abrogate Oxaliplatin-Induced Activation of the Notch-1 Signaling Pathway in Colon Cancer Cells Resulting in Enhanced Chemosensitivity in another window
Includes: Supplementary data
Journal Articles

The Cyclin-Dependent Kinase Inhibitor Flavopiridol Potentiates the Effects of Topoisomerase I Poisons by Suppressing Rad51 Expression in a p53-Dependent Manner

Grazia Ambrosini, Sharon L. Seelman, Li-Xuan Qin, Gary K. Schwartz
Journal: Cancer Research
Cancer Res (2008) 68 (7): 2312–2320.
https://doi.org/10.1158/0008-5472.CAN-07-2395
Published: 01 April 2008
View article titled, The Cyclin-Dependent Kinase Inhibitor Flavopiridol Potentiates the Effects of Topoisomerase I Poisons by Suppressing Rad51 Expression in a p53-Dependent Manner
Open the PDF for The Cyclin-Dependent Kinase Inhibitor Flavopiridol Potentiates the Effects of Topoisomerase I Poisons by Suppressing Rad51 Expression in a p53-Dependent Manner in another window
Includes: Supplementary data