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Journal Articles

Abstract 4108: Safety and feasibility of personalized neoantigen DC vaccines in postoperative esophagus squamous cell carcinoma: A Phase 1b trial

Yueyun Chen, Hua-Shan Shi, Yang Hu, Yong Yuan, Yu-Shang Yang, Heng Xu, Li Yang, Zhen-Yu Ding
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 4108.
https://doi.org/10.1158/1538-7445.AM2024-4108
Published: 22 March 2024
View article titled, Abstract 4108: Safety and feasibility of personalized neoantigen DC vaccines in postoperative esophagus squamous cell carcinoma: A Phase 1b trial
Journal Articles

Abstract PR06: Uncovering nuclear expulsion: chromatin-bound signals from dying cancer cells accelerate metastatic outgrowth through S100A4-RAGE pathway

Wooyong Park, Justin M Gray, Ronald J Holewinski, Thorkell Andresson, Jae Young So, Carmelo M Carmona-Rivera, Mariana J Kaplan, Steven D Cappell, Li Yang
Journal: Cancer Research
Cancer Res (2024) 84 (3_Supplement_1): PR06.
https://doi.org/10.1158/1538-7445.ADVBC23-PR06
Published: 01 February 2024
View article titled, Abstract PR06: Uncovering nuclear expulsion: chromatin-bound signals from dying cancer cells accelerate metastatic outgrowth through S100A4-RAGE pathway
Journal Articles

Abstract 6016: A comprehensive analysis of gut microbiome mediated epigenetic regulation of intestinal stem cells

Robert Craig Peery, Jiejun Shi, Leah Farmer, Li Yang, Emily Lawrence, Yumei Li, Wei Li, Lanlan Shen
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 6016.
https://doi.org/10.1158/1538-7445.AM2023-6016
Published: 04 April 2023
View article titled, Abstract 6016: A comprehensive analysis of gut microbiome mediated epigenetic regulation of intestinal stem cells
Journal Articles

Abstract 6010: Targeting p16 epimutation during lung cancer progression for anticancer therapy

Xiaomin Chen, Emily Brisnna Lawrence, Leah Farmer, Li Yang, Robert Craig Perry, David Joel Sequeira, Lanjing Zhang, Lanlan Shen
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 6010.
https://doi.org/10.1158/1538-7445.AM2023-6010
Published: 04 April 2023
View article titled, Abstract 6010: Targeting <em>p16</em> epimutation during lung cancer progression for anticancer therapy
Journal Articles

Abstract 6007: p16 epimutation modulates the tumor microenvironment and promotes malignancy of Apc-mutant colon cancer

Li Yang, Xiaomin Chen, Christy Lee, Jiejun Shi, Emily B. Lawrence, Lanjing Zhang, Yumei Li, Nan Gao, Sung Yun Jung, Chad J. Creighton, Jingyi Jessica Li, Ya Cui, Sumimasa Arimura, Wei Li, Lanlan Shen
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 6007.
https://doi.org/10.1158/1538-7445.AM2023-6007
Published: 04 April 2023
View article titled, Abstract 6007: <em>p16</em> epimutation modulates the tumor microenvironment and promotes malignancy of <em>Apc</em>-mutant colon cancer
Journal Articles

Abstract P1-05-08: Targeting tumor heterogeneity and breast cancer metastasis through the metastatic microenvironment mediated epigenetic reprogramming

Li Yang, Jae Young So, Nicolas Skrypek, Anand Merchant, George Nelson, Howard Yang, Maxwell Lee
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P1-05-08.
https://doi.org/10.1158/1538-7445.SABCS21-P1-05-08
Published: 15 February 2022
View article titled, Abstract P1-05-08: Targeting tumor heterogeneity and breast cancer metastasis through the metastatic microenvironment mediated epigenetic reprogramming
Journal Articles

Abstract 1667: A pilot study correlating baseline plasma levels of adenosine 2A receptor (A2aR) with acute phase reactants in advanced non-small cell lung cancer (NSCLC) patients treated with immune-checkpoint inhibitors

Justin D. McCallen, Abdul R. Naqash, Mona A. Marie, Nitika Sharma, Mahvish Muzaffar, Paul R. Walker, Li Yang
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 1667.
https://doi.org/10.1158/1538-7445.AM2021-1667
Published: 01 July 2021
View article titled, Abstract 1667: A pilot study correlating baseline plasma levels of adenosine 2A receptor (A2aR) with acute phase reactants in advanced non-small cell lung cancer (NSCLC) patients treated with immune-checkpoint inhibitors
Journal Articles

Abstract PO-080: Predicting relapse in patients with triple negative breast cancer (TNBC) using a deep-learning approach

Guangyuan Yu, Xuefei Li, Ting-Fang He, Tina Gruosso, Dongmei Zuo, Margarita Souleimanova, Valentina Muñoz Ramos, Atilla Omeroglu, Sarkis Meterissian, Marie-Christine Guiot, Li Yang, Yuan Yuan, Morag Park, Peter P. Lee, Herbert Levine
Journal: Cancer Research
Cancer Res (2020) 80 (21_Supplement): PO-080.
https://doi.org/10.1158/1538-7445.TUMHET2020-PO-080
Published: 03 November 2020
View article titled, Abstract PO-080: Predicting relapse in patients with triple negative breast cancer (TNBC) using a deep-learning approach
Journal Articles

Abstract 5577: Effective personalized neoantigen-based cancer vaccine combined with immune checkpoint inhibitor in the treatment of a patients with advanced squamous cell lung cancer failed with multi-line treatments

Song Gao, Zhongzheng Zhu, Jiaqian Wang, Juemin Fang, Yu Zhao, Zhuqing Liu, Guochao Wei, Huanlong Qin, Yuquan Wei, Heng Xu, Li Yang, Qing Xu
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 5577.
https://doi.org/10.1158/1538-7445.AM2020-5577
Published: 15 August 2020
View article titled, Abstract 5577: Effective personalized neoantigen-based cancer vaccine combined with immune checkpoint inhibitor in the treatment of a patients with advanced squamous cell lung cancer failed with multi-line treatments
Journal Articles

Abstract 417: Developing mouse models to dissect the function of a driver gene epimutation in lung tumorigenesis

Li Yang, Anusha Mandala, Yi Chen, Lanlan Shen
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 417.
https://doi.org/10.1158/1538-7445.AM2020-417
Published: 15 August 2020
View article titled, Abstract 417: Developing mouse models to dissect the function of a driver gene epimutation in lung tumorigenesis
Journal Articles

Abstract 1251: Epigenetics in early onset colorectal cancer (EOCRC)

Karen Riggins, Benjamin Musher, Michael Scheurer, Li Yang, Patricia Castro, Neda Zarrin-Khameh, Lanlan Shen
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 1251.
https://doi.org/10.1158/1538-7445.AM2020-1251
Published: 15 August 2020
View article titled, Abstract 1251: Epigenetics in early onset colorectal cancer (EOCRC)
Journal Articles

Induction of DNMT3B by PGE2 and IL6 at Distant Metastatic Sites Promotes Epigenetic Modification and Breast Cancer Colonization

Jae Young So, Nicolas Skrypek, Howard H. Yang, Anand S. Merchant, George W. Nelson, Wei-Dong Chen, Hiroki Ishii, Jennifer M. Chen, Gangqing Hu, Bhagelu R. Achyut, Esther C. Yoon, Liying Han, Chuanshu Huang, Margaret C. Cam, Keji Zhao, Maxwell P. Lee, Li Yang
Journal: Cancer Research
Cancer Res (2020) 80 (12): 2612–2627.
https://doi.org/10.1158/0008-5472.CAN-19-3339
Published: 15 June 2020
View article titled, Induction of DNMT3B by PGE2 and IL6 at Distant Metastatic Sites Promotes Epigenetic Modification and Breast Cancer Colonization
Open the PDF for Induction of DNMT3B by PGE2 and IL6 at Distant Metastatic Sites Promotes Epigenetic Modification and Breast Cancer Colonization in another window
Includes: Supplementary data
Journal Articles

Low-Dose IFNγ Induces Tumor Cell Stemness in Tumor Microenvironment of Non–Small Cell Lung Cancer

Mengjia Song, Yu Ping, Kai Zhang, Li Yang, Feng Li, Chaoqi Zhang, Shaoyan Cheng, Dongli Yue, Nomathamsanqa Resegofetse Maimela, Jiao Qu, Shasha Liu, Ting Sun, Zihai Li, Jianchuan Xia, Bin Zhang, Liping Wang, Yi Zhang
Journal: Cancer Research
Cancer Res (2019) 79 (14): 3737–3748.
https://doi.org/10.1158/0008-5472.CAN-19-0596
Published: 15 July 2019
View article titled, Low-Dose IFNγ Induces Tumor Cell Stemness in Tumor Microenvironment of Non–Small Cell Lung Cancer
Open the PDF for Low-Dose IFNγ Induces Tumor Cell Stemness in Tumor Microenvironment of Non–Small Cell Lung Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract LB-035: p16 epimutation cooperates with Apc mutation to promote colon cancer initiation and progression

Li Yang, Yue Chen, Matthew V. Holt, Feng Jin, Jong Min Choi, Sung Yun Jung, Anusha Mandala, Lanjing Zhang, Sayantani Goswami, Nan Gao, Yi Wang, Lanlan Shen
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): LB-035.
https://doi.org/10.1158/1538-7445.AM2019-LB-035
Published: 01 July 2019
View article titled, Abstract LB-035: <em>p16</em> epimutation cooperates with <em>Apc</em> mutation to promote colon cancer initiation and progression
Journal Articles

Abstract 4096: Clinical study of personalized neoantigen-based cancer vaccine in the treatment of advanced SCLC patients with brain metastasis: A case report

Song Gao, Yongchao Li, Zhenyu Ding, Heng Xu, Jiaqian Wang, Xianling Guo, Juemin Fang, Guochao Wei, Huanlong Qin, Yuquan Wei, Qing Xu, Li Yang
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 4096.
https://doi.org/10.1158/1538-7445.AM2019-4096
Published: 01 July 2019
View article titled, Abstract 4096: Clinical study of personalized neoantigen-based cancer vaccine in the treatment of advanced SCLC patients with brain metastasis: A case report
Journal Articles

Abstract 4500: Mechanisms of tumor-associated myeloid cells in modulating host immune microenvironment and metastatic progression

Hiroki Ishii, Christine Hollander, Tim Greten, Li Yang
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 4500.
https://doi.org/10.1158/1538-7445.AM2019-4500
Published: 01 July 2019
View article titled, Abstract 4500: Mechanisms of tumor-associated myeloid cells in modulating host immune microenvironment and metastatic progression
Journal Articles

Abstract 1055: Evaluation of immune checkpoint inhibitor efficacy in EGFR mutant tumors

Xuzhen Tang, Li Yang, Hui Qi, Xianzhi Zhai, Fuyang Wang, Xiangnan Qiang, Jie Xu, Xiaoran Qin, Qingyang Gu, Shaoyu Yan, Qunsheng Ji
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 1055.
https://doi.org/10.1158/1538-7445.AM2019-1055
Published: 01 July 2019
View article titled, Abstract 1055: Evaluation of immune checkpoint inhibitor efficacy in EGFR mutant tumors
Journal Articles

Abstract LB-348: Negative roles of C/EBPα in MDSC-mediated tumor angiogenesis and immune suppression

Peng Qu, Yongfen Min, Li Yang, Charles Lin
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): LB-348.
https://doi.org/10.1158/1538-7445.AM2018-LB-348
Published: 01 July 2018
View article titled, Abstract LB-348: Negative roles of C/EBPα in MDSC-mediated tumor angiogenesis and immune suppression
Journal Articles

Metformin-Induced Reduction of CD39 and CD73 Blocks Myeloid-Derived Suppressor Cell Activity in Patients with Ovarian Cancer

Lifeng Li, Liping Wang, Jieyao Li, Zhirui Fan, Li Yang, Zhen Zhang, Chaoqi Zhang, Dongli Yue, Guohui Qin, Tengfei Zhang, Feng Li, Xinfeng Chen, Yu Ping, Dan Wang, Qun Gao, Qianyi He, Lan Huang, Hong Li, Jianmin Huang, Xuan Zhao, Wenhua Xue, Zhi Sun, Jingli Lu, Jane J. Yu, Jie Zhao, Bin Zhang, Yi Zhang
Journal: Cancer Research
Series: Author Choice
Cancer Res (2018) 78 (7): 1779–1791.
https://doi.org/10.1158/0008-5472.CAN-17-2460
Published: 01 April 2018
View article titled, Metformin-Induced Reduction of CD39 and CD73 Blocks Myeloid-Derived Suppressor Cell Activity in Patients with Ovarian Cancer
Open the PDF for Metformin-Induced Reduction of CD39 and CD73 Blocks Myeloid-Derived Suppressor Cell Activity in Patients with Ovarian Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract 2843: DNMT3B mediated DNA methylation and epigenetic reprogramming of metastatic cancer cells

Jae Young So, Nicolas Skrypek, Xiang Wang, Anand Merchant, Howard Yang, Wei-Dong Chen, Gangqing Hu, Bhagelu R Achyut, Meggie Cam, Keji Zhao, Maxwell Lee, Li Yang
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 2843.
https://doi.org/10.1158/1538-7445.AM2017-2843
Published: 01 July 2017
View article titled, Abstract 2843: DNMT3B mediated DNA methylation and epigenetic reprogramming of metastatic cancer cells