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Journal Articles

Abstract 973: Comparative single cell transcriptome profiling of primary tumors, CTCs and metastatic sites from a bladder cancer PDX model

Tomas Vilimas, Brandie Fullmer, Alyssa Chapman, Rini Pauly, Ting-Chia Chang, Li Chen, Biswajit Das, Chris Karlovich, Yvonne Evrard, Melinda Hollingshead, Howard Stotler, Michelle Ahalt-Gottholm, Tara Grinnage-Pulley, Mickey Williams, James H. Doroshow
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 973.
DOI: https://doi.org/10.1158/1538-7445.AM2022-973
Published: 15 June 2022
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Journal Articles

Abstract 1913: Quality control workflows developed for the NCI Patient-Derived Models Repository using low pass whole genome sequencing and whole exome sequencing

Ting-Chia Chang, Li Chen, Biswajit Das, Yvonne A. Evrard, Chris A. Karlovich, Tomas Vilimas, Alyssa Chapman, Nikitha Nair, Luis Romero, Anna J. Lee Fong, Amanda Peach, Brandie Fullmer, Lindsay Dutko, Kelly Benauer, Gloryvee Rivera, Erin Cantu, Shahanawaz Jiwani, Nastaran Neishaboori, Tomas Forbes, Corinne Camalier, Luke Stockwin, Michael Mullendore, Michelle A. Eugeni, Dianne Newton, Melinda G. Hollingshead, Mickey P. Williams, James H. Doroshow
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 1913.
DOI: https://doi.org/10.1158/1538-7445.AM2022-1913
Published: 15 June 2022
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Journal Articles

Abstract 80: Genomic characterization of PDX models from rare cancer patients in the NCI Patient-Derived Models Repository

Li Chen, Rini Pauly, Ting-Chia Chang, Biswajit Das, Yvonne A. Evrard, Chris A. Karlovich, Tomas Vilimas, Alyssa Chapman, Nikitha Nair, Luis Romero, Anna Lee Fong, Amanda Peach, Shahanawaz Jiwani, Nastaran Neishaboori, Lindsay Dutko, Kelly Benauer, Gloryvee Rivera, Erin Cantu, Corinne Camalier, Thomas Forbes, Michelle Gottholm-Ahalt, John Carter, Suzanne Borgel, Chelsea McGlynn, Candace Mallow, Emily Delaney, Tiffanie Miner, Michelle A. Eugeni, Dianne Newton, Melinda G. Hollingshead, P. Mickey Williams, James H. Doroshow
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 80.
DOI: https://doi.org/10.1158/1538-7445.AM2022-80
Published: 15 June 2022
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Journal Articles

Abstract 3120: Method development for generation of PDX models from rapid autopsy samples for the NCI patient-derived models repository

Yvonne A. Evrard, Michelle Eugeni, Michelle Ahalt-Gottholm, Carrie Bonomi, Suzanne Borgel, Thomas C. Caffrey, John Carter, Ting-Chia Chang, Li Chen, Kevin Cooper, Biswajit Das, Emily Delaney, Kelly Dougherty, Eleonora Duregon, Stephanie Ecker, Joe Geraghty, Marion Gibson, Lauren Hicks, Jenna Hull, Sharon Int Veldt, Shahanawaz Jiwani, Chris A. Karlovich, Jade Loewenstein, Candace Mallow, Chelsea McGlynn, Justine Mills, Tiffanie Miner, Jowaly Schneider, Tia Shearer, Savanna Styers, Shannon Uzelac, Paul Grandgenett, Michael Hollingsworth, Jody E. Hooper, P. Mickey Williams, Melinda Hollingshead, James H. Doroshow
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 3120.
DOI: https://doi.org/10.1158/1538-7445.AM2022-3120
Published: 15 June 2022
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Journal Articles

Abstract P2-12-19: Platinum is essential in neoadjuvant treatment of triple negative breast cancer: A network meta-analysis

Junjie Li, Li Chen, Wei Tan, Fang Qi, Yang Zhang, Zhonghua Wang, Zhimin Shao
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P2-12-19.
DOI: https://doi.org/10.1158/1538-7445.SABCS21-P2-12-19
Published: 15 February 2022
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Journal Articles

Abstract P2-14-04: Updated data from FUTURE-C-PLUS: Combination of famitinib with camrelizumab plus nab-paclitaxel as first-line treatment for advanced, immunomodulatory triple-negative breast cancer, an open-label, single-arm, phase 2 trial

Li Chen, Yi-Zhou Jiang, Songyang Wu, Jiong Wu, Genhong Di, Guangyu Liu, Keda Yu, Lei Fan, Junjie Li, Yifeng Hou, Zhen Hu, Canming Chen, Xiaoyan Huang, Ayong Cao, Xin Hu, Shen Zhao, Xiaoyan Ma, Xiaoyu Zhu, Jianjun Zou, Wentao Yang, Zhonghua Wang, Zhi-ming Shao
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P2-14-04.
DOI: https://doi.org/10.1158/1538-7445.SABCS21-P2-14-04
Published: 15 February 2022
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Journal Articles

Abstract 3010: Single agent response comparisons in a large-scale, preclinical trial of rare cancer PDXs by the National Cancer Institute's patient-derived models repository

Yvonne A. Evrard, Sergio Y. Alcoser, Suzanne Borgel, Devynn Breen, John Carter, Tiffanie Chase, Alice Chen, Li Chen, Kristen Cooley, Biswajit Das, Emily Delaney, Lyndsay Dutko, Shannon Ecker, Thomas Forbes, Kyle Georgius, Michelle M. Gottholm-Ahalt, Tara Grinnage-Pulley, Sierra Hoffman, Chris Karlovich, Kimberly Klarmann, Shahanawaz Jiwani, Justine Mills, Malorie Morris, Michael Mullendore, Dianne Newton, Gloryvee Rivera, Howard Stotler, Jesse Stottlemyer, Savanna Styers, Cindy R. Timme, Debbie Trail, Shannon Uzelac, Tomas Vilimas, Thomas Walsh, Nikki Walters, P. Mickey Williams, Melinda G. Hollingshead, James H. Doroshow
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 3010.
DOI: https://doi.org/10.1158/1538-7445.AM2021-3010
Published: 01 July 2021
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Journal Articles

Abstract 3012: Patient-derived models of rare cancers in the National Cancer Institute's patient-derived models repository

Cindy R. Timme, Sergio Y. Alcoser, Devynn Breen, John Carter, Ting-Chia Chang, Alice Chen, Li Chen, Kristen Cooley, Biswajit Das, Emily Delaney, Michelle A. Eugeni, Michelle M. Gottholm-Ahalt, Tara Grinnage-Polley, Jenna Hull, Chris Karlovich, Kimberly Klarmann, Shahanawaz Jiwani, Candace Mallow, Chelsea McGlynn, Justine Mills, Malorie Morris, Michael Mullendore, Dianne Newton, Tia Shearer, Jesse Stottlemyer, Shannon Uzelac, Thomas Walsh, P. Mickey Williams, Yvonne A. Evrard, Melinda G. Hollingshead, James H. Doroshow
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 3012.
DOI: https://doi.org/10.1158/1538-7445.AM2021-3012
Published: 01 July 2021
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Journal Articles

Abstract 3139: Study of tumor heterogeneity and subclonality in primary pancreatic and metastatic sites from rapid autopsy patients in PDMR

Li Chen, Biswajit Das, Yvonne A. Evrard, Chris A. Karlovich, Tomas Vilimas, Amanda Peach, Chapman Alyssa, Nikitha Nair, Anna L. Fong, Luis Romero, Ting-Chia Chang, Shahanawaz Jiwani, Lindsay Dutko, Kelly Benauer, Marianne Morton, Kelly Dougherty, Michelle A. Eugeni, Dianne Newton, Melinda G. Hollingshead, P. Mickey Williams, James H. Doroshow
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 3139.
DOI: https://doi.org/10.1158/1538-7445.AM2021-3139
Published: 01 July 2021
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Journal Articles

Abstract 365: Detection of homologous recombination deficiency across cancer types by a real-time activity-based functional biomarker

Chih-Ying Lee, Kai-Hang Lei, Shih-Han Huang, Min-Yu Ko, Ko-Yu Chang, Po-Han Lin, Yu-Li Chen, Wen-Fang Cheng, Peter Chi
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 365.
DOI: https://doi.org/10.1158/1538-7445.AM2021-365
Published: 01 July 2021
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Journal Articles

Abstract 1328: Using whole-genome CRISPR-Cas9 screening to identify resistance networks in glioblastoma

Shreya Budhiraja, Shivani Baisiwala, Ella Perrault, Li Chen, Cheol Park, Chidiebere Awah, Crismita Dmello, Andrew Zolp, Adam Sonabend, Atique Ahmed
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 1328.
DOI: https://doi.org/10.1158/1538-7445.AM2021-1328
Published: 01 July 2021
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Journal Articles

Abstract PS6-21: High expression of MicroRNA-223 indicates better prognosis in triple negative breast cancer

Li Chen, Xiuzhi Zhu, Ling Yao, Zonghua Wang
Journal: Cancer Research
Cancer Res (2021) 81 (4_Supplement): PS6-21.
DOI: https://doi.org/10.1158/1538-7445.SABCS20-PS6-21
Published: 15 February 2021
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Journal Articles

Abstract PS4-39: Efficacy of combined CDK4/6 inhibitor and PARP inhibitor in the treatment of BRCA1 mutant triple negative breast cancer

Xiuzhi Zhu, Li Chen, Zhonghua Wang
Journal: Cancer Research
Cancer Res (2021) 81 (4_Supplement): PS4-39.
DOI: https://doi.org/10.1158/1538-7445.SABCS20-PS4-39
Published: 15 February 2021
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Journal Articles

Abstract 3275: GLS-010, a novel fully human anti-PD-1 mAb in patients with advanced tumor: Preliminary results of a Phase Ib clinical trial

Lin Shen, Jifang Gong, Yuqin Song, Dingwei Ye, Zhihao Lu, Siyang Wang, Peijian Peng, Jianhua Chen, Ou Jiang, Guojun Zhang, Yuxian Bai, Jianji Pan, Chunguang Ma, Li Chen, Yi Ba, Qi Li, Ping Lu, Lingli Zhang, Xianli Yin, Shanzhi Gu, Huilai Zhang, Hang Su, Yongsheng Jiang, Bangwei Cao, Weiqing Han, Yan Sun, Feng Zhang, Weiwei Ouyang, Haiying Dong, Jianming Guo, Yabing Guo, Chongyuan Xu, Junyuan Qi, Li Wang, Jun Lv, Xiang Wang, Chris Chen, Jing Li, Yong Zheng, Ge Jin, Yining Yang, Guodong Zhao, Fan Yang, Kehui Xu, Xiangying Liang, Zhaoyang Pan, Haijin Meng
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 3275.
DOI: https://doi.org/10.1158/1538-7445.AM2020-3275
Published: 15 August 2020
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Abstract 3916: Patient-derived organoid and cell culture models from the NCI Patient-Derived Models Repository (NCI PDMR) preserve genomic stability and heterogeneity of patient tumor specimens

Biswajit Das, Yvonne A. Evrard, Li Chen, Rajesh Patidar, Tomas Vilimas, Justine N. McCutcheon, Amanda L. Peach, Nikitha V. Nair, Thomas D. Forbes, Brandie A. Fullmer, Anna J. Lee Fong, Luis E. Romero, Alyssa K. Chapman, Kelsey A. Conley, Robin D. Harrington, Shahanawaz S. Jiwani, Peng Wang, Michelle M. Gottholm-Ahalt, Erin N. Cantu, Gloryvee Rivera, Lindsay M. Dutko, Kelly M. Benauer, Vishnuprabha R. Kannan, Carrie A. Bonomi, Kelly M. Dougherty, Joseph P. Geraghty, Marion V. Gibson, Savanna S. Styers, Abigail J. Walke, Jenna E. Moyer, Anna Wade, Mariah L. Baldwin, Kaitlyn A. Arthur, Kevin J. Plater, Luke Stockwin, Matthew R. Murphy, Michael E. Mullendore, Dianne L. Newton, Melinda G. Hollingshead, Chris A. Karlovich, Paul M. Williams, James H. Doroshow
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 3916.
DOI: https://doi.org/10.1158/1538-7445.AM2020-3916
Published: 15 August 2020
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Journal Articles

Abstract 5906: NUAK2 is highly overexpressed in ovarian cancer and the overexpression of its nuclear form correlates with tumor aggressiveness

Li Chen, Oscar Gee-Wan Wong, Ivy Tsz-Lo Wong, Annie Nga-Yin Cheung
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 5906.
DOI: https://doi.org/10.1158/1538-7445.AM2020-5906
Published: 15 August 2020
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Journal Articles

Abstract 3554: Genomic landscape of acquired uniparental disomy in NCI PDMR patient derived xenograft models

Rajesh Patidar, Li Chen, Chris A. Karlovich, Biswajit Das, Yvonne A. Evrard, Tomas Vilimas, Justine N. McCutcheon, Amanda L. Peach, Nikitha V. Nair, Thomas D. Forbes, Brandie A. Fullmer, Anna J. Lee Fong, Luis E. Romero, Alyssa K. Chapman, Kelsey A. Conley, Robin D. Harrington, Shahanawaz S. Jiwani, Peng Wang, Michelle M. Gottholm Ahalt, Erin N. Cantu, Gloryvee Rivera, Lindsay M. Dutko, Kelly M. Benauer, Vishnuprabha R. Kannan, Suzanne D. Borgel, John P. Carter, Jesse M. Stottlemyer, Tiffanie L. Miner, Devynn R. Breen, Emily T. Delaney, Chelsea A. McGlynn, Candace N. Mallow, Marianne Radzyminski, Shannon N. Uzelac, Sergio Y. Alcoser, Tara L. Grinnage-Pulley, Michelle A. Eugeni, Dianne L. Newton, Melinda G. Hollingshead, Paul M. Williams, James H. Doroshow
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 3554.
DOI: https://doi.org/10.1158/1538-7445.AM2020-3554
Published: 15 August 2020
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Journal Articles

Clinical Evolution of Epithelial–Mesenchymal Transition in Human Carcinomas

Tony Navas, Robert J. Kinders, Scott M. Lawrence, Katherine V. Ferry-Galow, Suzanne Borgel, Melinda G. Hollingshead, Apurva K. Srivastava, Sergio Y. Alcoser, Hala R. Makhlouf, Rodrigo Chuaqui, Deborah F. Wilsker, Mariam M. Konaté, Sarah B. Miller, Andrea Regier Voth, Li Chen, Tomas Vilimas, Jyothi Subramanian, Lawrence Rubinstein, Shivaani Kummar, Alice P. Chen, Donald P. Bottaro, James H. Doroshow, Ralph E. Parchment
Journal: Cancer Research
Cancer Res (2020) 80 (2): 304–318.
DOI: https://doi.org/10.1158/0008-5472.CAN-18-3539
Published: 15 January 2020
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Journal Articles

Abstract LB-266: A novel computational combination-therapy prediction algorithm (secDrug) identifies the Nampt inhibitor FK866 reverses PI-resistant multiple myeloma

Harish Kumar, Ujjal Kumar Mukherjee, Sayak Chakravarti, Li Chen, Brian Van ness, Amit Kumar Mitra
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): LB-266.
DOI: https://doi.org/10.1158/1538-7445.AM2019-LB-266
Published: 01 July 2019
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Abstract 1056: Xenograft-associated B cell lymphoproliferative disease (XABLD) as a surrogate model to study Epstein-Barr virus (EBV) driven B cell Diseases

Tomas Vilimas, Gloryvee Rivera, Brandie Fullmer, Wiem Lassoued, Lindsay Dutko, Amanda Peach, Corinne Camalier, Li Chen, Rajesh Patidar, Suzanne Borgel, John Carter, Howard Stotler, Raymond Divelbiss, Jesse Stottlemyer, Michelle M. Gottholm-Ahalt, Michelle Crespo-Eugeni, Sean McDermott, William Jacob, Liqiang Xi, Pallavi Galera, Yvonne A. Evrard, Melinda G. Hollingshead, Elaine S. Jaffe, Mark Raffeld, Biswajit Das, Chris Karlovich, Vivekananda Datta, James H. Doroshow, P. Mickey Williams
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 1056.
DOI: https://doi.org/10.1158/1538-7445.AM2019-1056
Published: 01 July 2019
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